SCHEMBL43977

SCHEMBL43977

N[C@@H](Cc1ccccc1Cl)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.58
ALPI P09923 1/20 0.58
PTGS1 P23219 1/20 0.58
XIAP P98170 1/20 0.58
SLC7A5 Q01650 1/20 0.58
NOS3 P29474 3/20 0.57
NOS1 P29475 3/20 0.57
NOS2 P35228 3/20 0.57
PPARG P37231 1/20 0.53
PPARA Q07869 1/20 0.53
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
MAPT P10636 3/20 0.51
KDM4E B2RXH2 2/20 0.51
LMNA P02545 2/20 0.51
BLM P54132 2/20 0.51
PMP22 Q01453 2/20 0.51
HIF1A Q16665 2/20 0.51
MPO P05164 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35491891 1.00 PKM (0.58) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL29351556 1.00 PKM (0.58) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL298903 1.00 PKM (0.58) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL43976 1.00 PKM (0.58) PKMALPIPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL21904241 0.98 PKM (0.56) PKMALPIPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL1514957 0.98 PKM (0.56) PKMALPIPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL27479478 0.98 PKM (0.56) PKMALPIPTGS1XIAPSLC7A5
Methyl Alcohol SCHEMBL28880032 0.96 NOS3 (0.56) PKMALPIPTGS1XIAPSLC7A5
Methyl Alcohol SCHEMBL29067173 0.95 NOS3 (0.55) PKMALPIPTGS1XIAPSLC7A5
SCHEMBL13971424 0.86 SLC7A5 (0.69) PKMALPIPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3092 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122017084-A Full component and blood-entering component of cough relieving powder and detection method thereof 山西中医药大学 2026-05-12 CN claimed
EP-4729520-A1 CONFORMATIONALLY FIXED DIPROLINE MIMETICS AND THEIR USE Prosion GmbH (DE) 2026-04-22 EP claimed
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
WO-2025128149-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-19 WO claimed
US-20250186630-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING PEPTIDES VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-12 US claimed
CN-116359390-B Method for identifying three kinds of medicinal rhizoma polygonati varieties 杭州市农业科学研究院 2025-06-03 CN claimed
CN-120064483-A Detection method for targeting neurotransmitter and metabolite thereof 深圳市中医院 2025-05-30 CN claimed
WO-2025109003-A1 P-CADHERIN LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-05-30 WO claimed
CN-119757607-A Biomarker, application, kit and identification method for identifying high-virulence klebsiella pneumoniae 苏州木芮生物科技有限公司 2025-04-04 CN claimed
CN-1176102-A Use of nonpeptide bradykinin antagonists for treatment and prevention of chronic fibrogenetic liver disorders acute liver disorders and complications associated therewith HOECHST AG (DE) 1998-03-18 CN claimed
CN-1169992-A Sulfur-containing heterocyclic brad-ykinin antagcnists, process for their preparation and their use HOECHST AG (DE) 1998-01-14 CN claimed
EP-0808838-A1 Sulfur-containing heterocyclic bradykinin antagonists, processes for their production and use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-26 EP claimed
EP-0808627-A2 Use of non-peptide bradykinin antagonists for treating and preventing chronic fibrogenetic liver diseases, acute liver diseases and complications thereof HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-26 EP claimed
EP-0808628-A2 Use of non-peptide bradykinin antagonists for treating and preventing chronic fibrogenetic liver diseases, acute liver diseases and complications thereof HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-26 EP claimed
US-5648333-A POLYPEPTIDES FOR ANTIINFLAMMATORY AGENTS, WOUND HEALING AGENTS, ANTIALLERGENS OR CARDIOVASCULAR DISORDERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-15 US claimed
EP-0370453-B1 Peptides having a Brady kinine-inhibiting activity HOECHST AG (DE) 1994-06-15 EP claimed
CN-1049505-A Peptide class with bradykinin antagonistic action HOECHST AG (DE) 1991-02-27 CN claimed
EP-0413277-A1 Peptide antagonists of bradykinin HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-20 EP claimed
EP-0370453-A2 Peptides having a Brady kinine-inhibiting activity HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed