Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | RHEB | Q15382 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27350271 | 0.75 | DAO (0.50) | ALDH1A1L3MBTL1FFAR1DAORHEB | |
| SCHEMBL29941707 | 0.71 | ALDH1A1 (0.77) | ALDH1A1L3MBTL1NPSR1MAPTKDM4E | |
| SCHEMBL15312177 | 0.71 | SRD5A2 (0.59) | ALDH1A1DAORHEBPOLBMAPT | |
| SCHEMBL3875107 | 0.71 | ALDH1A1 (0.77) | ALDH1A1L3MBTL1NPSR1MAPTKDM4E | |
| SCHEMBL29761766 | 0.71 | SRD5A2 (0.59) | ALDH1A1DAORHEBPOLBMAPT | |
| SCHEMBL4180872 | 0.70 | HPGD (0.57) | ALDH1A1L3MBTL1POLBMAPTKDM4E | |
| SCHEMBL13949499 | 0.69 | PIN1 (0.49) | ALDH1A1DAOMAPTKDM4EHPGD | |
| SCHEMBL23395630 | 0.69 | PTPN1 (0.49) | ALDH1A1L3MBTL1POLBNPSR1KDM4E | |
| SCHEMBL1244211 | 0.68 | DAO (0.47) | ALDH1A1DAOMAPTKDM4ESRD5A2 | |
| Lithium SCHEMBL30975927 | 0.68 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1SCN9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306169-A1 | Use of Fused Pyrrole Carboxylic Acids for the Treatment of Neurodegenerative and Psychiatric Diseases and D-Amino Acid Oxidase Inhibitors | BRANDISH PHILIP E | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306169-A1 | Use of Fused Pyrrole Carboxylic Acids for the Treatment of Neurodegenerative and Psychiatric Diseases and D-Amino Acid Oxidase Inhibitors | DAO, DDO, MAOB | ALDH1A1 337/4885L3MBTL1 4422/4885FFAR1 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.