Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397875 | 1.00 | HRH3 (0.64) | HRH3SIGMAR1 | |
| SCHEMBL776337 | 0.86 | HRH3 (0.72) | HRH3SIGMAR1 | |
| SCHEMBL11084414 | 0.85 | SIGMAR1 (0.67) | HRH3SIGMAR1 | |
| SCHEMBL775581 | 0.85 | HRH3 (0.71) | HRH3SIGMAR1 | |
| SCHEMBL11084417 | 0.85 | SIGMAR1 (0.67) | HRH3SIGMAR1 | |
| SCHEMBL776259 | 0.82 | HRH3 (0.64) | HRH3SIGMAR1 | |
| SCHEMBL4388673 | 0.82 | CNR1 (0.56) | — | |
| SCHEMBL19403634 | 0.82 | CNR1 (0.56) | — | |
| SCHEMBL19403770 | 0.82 | CNR1 (0.56) | — | |
| SCHEMBL4388676 | 0.82 | CNR1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247499-A1 | SULFONYLATED PIPERAZINES AS CANNABINOID-1 RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247499-A1 | SULFONYLATED PIPERAZINES AS CANNABINOID-1 RECEPTOR MODULATORS | CNR1, CNR2, FAAH | HRH3 233/4885SIGMAR1 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.