SCHEMBL4397929

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4400652	0.91	OPRK1 (0.46)	POLBOPRK1EPHX2MAPTNPC1
	SCHEMBL4401002	0.91	OPRK1 (0.46)	POLBOPRK1EPHX2MAPTNPC1
	SCHEMBL13880959	0.89	POLB (0.46)	POLBMAPTNPC1SMN1; SMN2HSD17B10
	SCHEMBL13643855	0.88	OPRK1 (0.41)	POLBOPRK1EPHX2MAPTNPC1
	SCHEMBL4400114	0.87	POLB (0.39)	POLBOPRK1EPHX2MAPTNPC1
	SCHEMBL14968453	0.86	POLB (0.46)	POLBOPRK1EPHX2MAPTNPC1
	SCHEMBL4400107	0.86	POLB (0.43)	POLBOPRK1EPHX2MAPTNPC1
	SCHEMBL13643867	0.85	OPRK1 (0.44)	POLBOPRK1EPHX2MAPTALDH1A1
	SCHEMBL13643854	0.85	POLB (0.39)	POLBOPRK1EPHX2MAPTNPC1
	SCHEMBL13880962	0.85	ALDH1A1 (0.44)	POLBMAPTSMN1; SMN2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.