Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 6/20 | 0.51 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160859 | 0.86 | CYP17A1 (0.51) | CYP17A1SSTR4GSK3BMAPTPDE2A | |
| Ammonia Solution, Strong SCHEMBL28408262 | 0.84 | CYP17A1 (0.50) | CYP17A1SSTR4GSK3BMAPTPDE2A | |
| SCHEMBL15733041 | 0.79 | CYP17A1 (0.42) | CYP17A1SSTR4GSK3BMAPTGSK3A | |
| SCHEMBL15791321 | 0.79 | MAPT (0.52) | CYP17A1GSK3BMAPTGSK3AKDM4E | |
| SCHEMBL4079147 | 0.77 | CA12 (0.54) | SSTR4MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL4076045 | 0.76 | PDE10A (0.40) | CYP17A1SSTR4PDE2APDE10ACYP1A2 | |
| SCHEMBL17610600 | 0.75 | CYP17A1 (0.40) | CYP17A1SSTR4GSK3BMAPTGSK3A | |
| SCHEMBL28151932 | 0.75 | CYP17A1 (0.45) | CYP17A1SSTR4GSK3BMAPTGSK3A | |
| SCHEMBL29530887 | 0.75 | GSK3B (0.43) | CYP17A1GSK3BMAPTGSK3AKDM4E | |
| SCHEMBL4070510 | 0.74 | PDE5A (0.40) | SSTR4MAPTKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104257680-A | Pill for eradicating helicobacter pylori | WANG DEPU | 2015-01-07 | — | — | CN | claimed |
| EP-2308492-B1 | Process for preparing lansoprazole | KRKA TOVARNA ZDRAVIL D D NOVO MESTO (SI) | 2016-09-14 | — | — | EP | disclosed |
| CN-103202820-B | A kind of stable lansoprazole intestine dissolving capsule and preparation method thereof | Zhejiang Yatai Pharmaceutical Co., Ltd. (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-103271884-B | Lansoprazole composition and preparation method thereof | YOUCARE PHARMACEUTICAL GROUP Co.,Ltd. (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-104257680-A | Pill for eradicating helicobacter pylori | WANG DEPU | 2015-01-07 | — | — | CN | disclosed |
| US-8829014-B2 | Thiazole and thiophene analogues, and their use in treating autoimmune diseases and cancers | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2007393-B1 | THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS | UNIV LOUISIANA STATE (US) | 2013-08-21 | — | — | EP | disclosed |
| CN-101884629-B | Controlled release preparation | TAKEDA PHARMACEUTICAL | 2013-08-21 | — | — | CN | disclosed |
| US-20120283268-A1 | Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers | GIORDANO ANTHONY (US) | 2012-11-08 | — | — | US | disclosed |
| US-8217037-B2 | Thiazole and thiophene analogues, and their use in treating autoimmune diseases and cancers | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2012-07-10 | — | — | US | disclosed |
| EP-2308492-A1 | Process for preparing lansoprazole | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2011-04-13 | — | — | EP | disclosed |
| EP-1838314-B1 | PROCESS FOR PREPARING LANSOPRAZOLE | KRKA TOVARNA ZDRAVIL D D NOVO (SI) | 2010-07-28 | — | — | EP | disclosed |
| US-7662968-B2 | Process for preparing lansoprazole | KRKA tovarna zdravil, d.d.. (SI) | 2010-02-16 | — | — | US | disclosed |
| US-7662968-B2 | Process for preparing lansoprazole | KRKA tovarna zdravil, d.d.. (SI) | 2010-02-16 | — | — | US | disclosed |
| US-20090306073-A1 | Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers | B.V. PATEL PHARMACEUTICAL EDUCATION & RESEARCH DEVELOPMENT (PERD) CENTRE (IN) | 2009-12-10 | — | — | US | disclosed |
| US-20070259049-A1 | Process for preparing lansoprazole | KRKA, TOVARNA ZDRAVIL, D.D. | 2007-11-08 | — | — | US | disclosed |
| US-20070259049-A1 | Process for preparing lansoprazole | KRKA, TOVARNA ZDRAVIL, D.D. | 2007-11-08 | — | — | US | disclosed |
| EP-1368338-A4 | METHOD OF PREPARING LANSOPRAZOLE AND ITS INTERMEDIATE | HANSOL CHEMIENCE CO LTD (KR) | 2004-09-15 | — | — | EP | disclosed |
| EP-1368338-A1 | METHOD OF PREPARING LANSOPRAZOLE AND ITS INTERMEDIATE | Chemtech Research Incorporation (KR) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002074766-A1 | METHOD OF PREPARING LANSOPRAZOLE AND ITS INTERMEDIATE | CHEMTECH RESEARCH INCORPORATION (KR) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259049-A1 | Process for preparing lansoprazole | CYP51A1, CYP2D6, CYP3A4 | CYP17A1 836/4885SSTR4 264/4885GSK3B 3535/4885 |
| US-20090306073-A1 | Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers | TPMT, TST, SSB | CYP17A1 3266/4885SSTR4 1993/4885GSK3B 4203/4885 |
| US-20120283268-A1 | Thiazole and Thiophene Analogues, and Their Use in Treating Autoimmune Diseases and Cancers | TPMT, TST, SSB | CYP17A1 3266/4885SSTR4 1993/4885GSK3B 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.