Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441577 | 0.88 | ALDH1A1 (0.44) | IRAK4GRM5CCR1ALDH1A1KDM4E | |
| SCHEMBL14837551 | 0.85 | ALDH1A1 (0.37) | GRM5CCR1ALDH1A1KDM4ERECQL | |
| SCHEMBL441326 | 0.84 | TTR (0.41) | IRAK4ALDH1A1MAPTMEN1GAA | |
| SCHEMBL440227 | 0.82 | ALDH1A1 (0.40) | IRAK4ALDH1A1KDM4EFLT3KCNH2 | |
| SCHEMBL14837507 | 0.81 | CCR1 (0.37) | GRM5CCR1ALDH1A1KDM4ERECQL | |
| SCHEMBL440115 | 0.80 | HRH3 (0.35) | IRAK4GRM5ALDH1A1FLT3MAPT | |
| SCHEMBL14837937 | 0.77 | HAO1 (0.35) | CCR1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL14837508 | 0.76 | ELANE (0.35) | GRM5CCR1ALDH1A1KDM4ERECQL | |
| SCHEMBL30404348 | 0.76 | TSHR (0.47) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL2000959 | 0.75 | ALDH1A1 (0.41) | CCR1ALDH1A1MAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748420-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-8604040-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| EP-2576539-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2011147765-A1 | PYRIDINYLCARBOXYLIC ACID DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | IRAK4 3410/4885GRM5 1444/4885CCR1 488/4885 |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | IRAK4 3478/4885GRM5 1220/4885CCR1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.