Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439795 | 0.84 | IRAK4 (0.40) | ALDH1A1IRAK4MEN1GAAMAPT | |
| SCHEMBL440227 | 0.74 | ALDH1A1 (0.40) | ALDH1A1IRAK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2638900 | 0.70 | HSD11B1 (0.56) | TTRHSD11B1PRKCQCYP1A2CYP2D6 | |
| SCHEMBL440115 | 0.70 | HRH3 (0.35) | ALDH1A1IRAK4HRH3MEN1LMNA | |
| SCHEMBL14837551 | 0.69 | ALDH1A1 (0.37) | ALDH1A1MEN1GAAMAPTKMT2A | |
| SCHEMBL27665047 | 0.69 | PRKCQ (0.62) | TTRIRAK4HSD11B1PRKCQCYP1A2 | |
| SCHEMBL31078476 | 0.67 | GNE (0.44) | TTRHSD11B1HSD17B14GAA | |
| SCHEMBL9005452 | 0.67 | PRKCQ (0.63) | TTRIRAK4HSD11B1PRKCQCYP1A2 | |
| SCHEMBL836939 | 0.67 | GNE (0.60) | TTRALDH1A1HSD11B1PRKCQHSD17B14 | |
| SCHEMBL14879835 | 0.67 | GNE (0.56) | TTRALDH1A1HSD11B1PRKCQHSD17B14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748420-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-8604040-B2 | Pyridinylcarboxylic acid derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2013-12-10 | — | — | US | disclosed |
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065197-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | TTR 1986/4885ALDH1A1 1009/4885IRAK4 3410/4885 |
| US-20140066442-A1 | Pyridinylcarboxylic Acid Derivatives as Fungicides | PNPO, CYP1A1, CHRM1 | TTR 2238/4885ALDH1A1 1051/4885IRAK4 3478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.