Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252387 | 0.96 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAKDM4EPKMKMT2A | |
| SCHEMBL4250993 | 0.89 | MAOB (0.47) | SMN1; SMN2LMNAKDM4EKMT2ASMO | |
| SCHEMBL4247565 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAKDM4EKMT2ASMO | |
| SCHEMBL4398189 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAKDM4EKMT2ASMO | |
| SCHEMBL4245119 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKDM4EKMT2ASMO | |
| SCHEMBL4071799 | 0.85 | MAOB (0.50) | SMN1; SMN2LMNAKMT2ASMODRD4 | |
| SCHEMBL4070453 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAKDM4EKMT2AL3MBTL1 | |
| SCHEMBL4244857 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAKDM4EKMT2AOPRM1 | |
| SCHEMBL4252058 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAKDM4EKMT2ASMO | |
| SCHEMBL4246582 | 0.83 | DRD3 (0.54) | LMNAKDM4EOPRM1OPRK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-12-10 | — | — | US | claimed |
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306039-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IP6K1, IP6K2, IP6K3 | SMN1; SMN2 3497/4885LMNA 2895/4885KDM4E 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.