Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886131 | 0.90 | PTGER1 (0.43) | KDM4ETAAR1ALDH1A1HPGDCTBP2 | |
| SCHEMBL16542314 | 0.86 | TAAR1 (0.44) | KDM4ETAAR1ALDH1A1HPGDCTBP2 | |
| SCHEMBL8088574 | 0.85 | TAAR1 (0.47) | KDM4ETAAR1ALDH1A1HPGDCTBP2 | |
| SCHEMBL13886097 | 0.82 | MAOB (0.49) | KDM4EALDH1A1HPGDCTBP2THRA | |
| SCHEMBL9181973 | 0.81 | TAAR1 (0.58) | KDM4ETAAR1ALOX5PTGS2HCAR2 | |
| SCHEMBL3082606 | 0.80 | POLB (0.56) | TAAR1L3MBTL1ALOX5KMT2A | |
| SCHEMBL13886118 | 0.80 | TAAR1 (0.47) | KDM4ETAAR1L3MBTL1CHRM1FFAR4 | |
| SCHEMBL3891807 | 0.79 | KMT2A (0.47) | TAAR1CTBP2L3MBTL1FFAR1KMT2A | |
| SCHEMBL13886094 | 0.79 | TAAR1 (0.46) | KDM4ETAAR1ALDH1A1ALOX5FFAR4 | |
| SCHEMBL16542334 | 0.79 | FFAR4 (0.40) | L3MBTL1FFAR4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007372-B1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2015-03-04 | — | — | EP | disclosed |
| EP-2007372-B1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8703821-B2 | Dialkyl ether delivery agents | EMISPHERE TECHNOLOGIES INC. (US) | 2014-04-22 | — | — | US | disclosed |
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2009-04-09 | — | — | US | disclosed |
| EP-2007372-A2 | DIALKYL ETHER DELIVERY AGENTS | Emisphere Technologies, Inc. (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007121471-A2 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121471-A2 | DIALKYL ETHER DELIVERY AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
| US-6080869-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-06-27 | — | — | US | disclosed |
| EP-0850232-B1 | BENZOTHIAZOLONE DERIVATIVES | ASTRA PHARMA PROD (GB) | 2000-03-15 | — | — | EP | disclosed |
| US-6008365-A | ADRENORECEPTOR AGONISTS AND DOPAMINE DA2-RECEPTOR AGONISTS, USEFUL IN THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-12-28 | — | — | US | disclosed |
| US-5977384-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| US-5973167-A | Intermediates for making benzothiazolone derivatives | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-10-26 | — | — | US | disclosed |
| US-5846989-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |
| EP-0850232-A1 | BENZOTHIAZOLONE DERIVATIVES | Astra Pharmaceuticals Limited (GB) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997010227-A1 | BENZOTHIAZOLONE DERIVATIVES | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090092580-A1 | DIALKYL ETHER DELIVERY AGENTS | LIPA, SLC10A1, ABCB11 | KDM4E 1435/4885TAAR1 3015/4885ALDH1A1 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.