SCHEMBL4398874

SCHEMBL4398874

CCCCOc1cc2ccccc2cc1[C]=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.50
GAA P10253 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
PPARG P37231 6/20 0.44
PPARA Q07869 6/20 0.44
LTA4H P09960 2/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
MCHR1 Q99705 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27768841 0.82 TLR8 (0.62) TLR8GAATDP1L3MBTL1CYP1A2
SCHEMBL1790720 0.80 ALDH1A1 (0.44) GAAL3MBTL1CYP1A2CYP2C9CYP2C19
SCHEMBL195415 0.80 CYP1A2 (0.55) TLR8GAATDP1L3MBTL1CYP1A2
SCHEMBL347826 0.79 TLR8 (0.58) TLR8GAATDP1L3MBTL1CYP1A2
SCHEMBL8050540 0.77 TDP1 (0.43) GAATDP1L3MBTL1LTA4HCNR1
SCHEMBL31290761 0.77 TLR8 (0.63) TLR8GAATDP1L3MBTL1CYP1A2
SCHEMBL19549638 0.76 ALDH1A1 (0.48)
SCHEMBL8749651 0.76 ALDH1A1 (0.48)
SCHEMBL28664729 0.76 ALDH1A1 (0.48)
SCHEMBL19549611 0.76 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2924053-B1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID COMPOUND OR SALT THEREOF GLYTECH INC (JP) 2020-11-11 EP disclosed
US-9708413-B2 Glycosylated linker, compound containing glycosylated linker moiety and physiologically active substance moiety or salt thereof, and methods for producing said compound or salt thereof GLYTECH, INC. (JP) 2017-07-18 US disclosed
US-20150299337-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID U OR SALT THEREOF GLYTECH INC (JP) 2015-10-22 US disclosed
EP-2924053-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID COMPOUND OR SALT THEREOF Glytech, Inc. (JP) 2015-09-30 EP disclosed
CN-104918962-A Glycosylated linker, compound containing glycosylated linker moiety and physiologically active substance moiety or salt thereof, and methods for producing said compound or salt thereof GLYTECH INC 2015-09-16 CN disclosed
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME MITSUI CHEMICALS, INC. (JP) 2009-12-10 US disclosed
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
CN-100401400-C Rewritable optical information recording medium and recording/reproducing method, recording/reproducing device SONY CORP MITSUI CHEMICALS INC (JP) 2008-07-09 CN disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
US-20030194646-A1 Mono-, di-, and triazaporphyrin compounds optionally in the form of a metal or metalloid complex MITSUI CHEMICALS, INC. (JP) 2003-10-16 US disclosed
US-6627288-B1 Optical recording medium and porphycene compound MITSUI CHEMICALS, INC. (JP) 2003-09-30 US disclosed
CN-1434771-A Optical recording medium and azaporphyrin compound MITSUI CHEMICALS INC (JP) 2003-08-06 CN disclosed
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
CN-1406182-A Benzodiazolyl compound, optical recording medium compound MITSUI CHEMICALS INC (JP) 2003-03-26 CN disclosed
EP-1262966-A2 Optical recording medium and novel azaporphyrin compound Mitsui Chemicals, Inc. (JP) 2002-12-04 EP disclosed
EP-1247655-A1 OPTICAL RECORDING MEDIUM AND NOVEL AZAPORPHYRIN COMPOUNDS Mitsui Chemicals, Inc. (JP) 2002-10-09 EP disclosed
EP-1245571-A1 BENZBISAZOLE COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE COMPOUND Mitsui Chemicals, Inc. (JP) 2002-10-02 EP disclosed
CN-1338738-A Optical recording media and porphinoid compound MITSUI CHEMICALS INC (JP) 2002-03-06 CN disclosed
EP-1180765-A1 Optical recording medium and porphycene compound Mitsui Chemicals, Inc. (JP) 2002-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299337-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID U OR SALT THEREOF CD44, CSGALNACT1, UGGT1 TLR8 101/4885GAA 187/4885TDP1 4046/4885
US-20090306376-A1 OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME CACNA1B, KCNN4, KCNN2 TLR8 2761/4885GAA 4637/4885TDP1 4127/4885
US-20030091931-A1 Benzbisazole compound and optical recording medium containing the compound DAO, CACNA1I, KCNB2 TLR8 2849/4885GAA 2352/4885TDP1 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.