SCHEMBL4400265

SCHEMBL4400265

c1ccc2c(c1)c1ccccc1n2-c1cc(-c2cc(-n3c4ccccc4c4ccccc43)nc(-n3c4ccccc4c4ccccc43)c2)cc(-n2c3ccccc3c3ccccc32)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
GPR3 P46089 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
POLB P06746 1/20 0.38
MKNK1 Q9BUB5 1/20 0.37
MKNK2 Q9HBH9 1/20 0.37
ALDH1A1 P00352 3/20 0.36
DUSP3 P51452 1/20 0.34
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.33
HPGD P15428 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30232779 0.94 KDM4E (0.47) KDM4EL3MBTL1ATMGPR3CYP1A2
SCHEMBL11992467 0.94 KDM4E (0.47) KDM4EL3MBTL1ATMGPR3CYP1A2
SCHEMBL24609446 0.92 KDM4E (0.45) KDM4EL3MBTL1ATMGPR3POLB
SCHEMBL14426138 0.92 KDM4E (0.41) KDM4EL3MBTL1ATMGPR3CYP1A2
SCHEMBL14426136 0.91 KDM4E (0.44) KDM4EL3MBTL1ATMPOLBMKNK1
SCHEMBL14426139 0.91 KDM4E (0.44) KDM4EL3MBTL1ATMPOLBMKNK1
SCHEMBL14426140 0.91 KDM4E (0.44) KDM4EL3MBTL1ATMPOLBMKNK1
SCHEMBL14426137 0.91 KDM4E (0.44) KDM4EL3MBTL1ATMPOLBMKNK1
SCHEMBL14426130 0.89 KDM4E (0.38) KDM4EL3MBTL1ATMGPR3MKNK1
SCHEMBL14426132 0.89 KDM4E (0.38) KDM4EL3MBTL1ATMGPR3MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10276637-B2 Organic EL multi-color light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-30 US disclosed
US-RE46368-E1 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-18 US disclosed
US-RE46368-E1 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-18 US disclosed
EP-1858094-B1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE PIONEER CORP (JP) 2017-03-08 EP disclosed
US-8911886-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-12-16 US disclosed
US-8911886-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-12-16 US disclosed
US-20140159023-A1 ORGANIC EL MULTI-COLOR LIGHT-EMITTING DEVICE Idemitsu Co., Ltd. (JP) 2014-06-12 US disclosed
US-20140159023-A1 ORGANIC EL MULTI-COLOR LIGHT-EMITTING DEVICE Idemitsu Co., Ltd. (JP) 2014-06-12 US disclosed
US-8580398-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-11-12 US disclosed
US-8580398-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-11-12 US disclosed
US-20120235129-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICES AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-09-20 US disclosed
US-20120235129-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICES AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-09-20 US disclosed
US-8168307-B2 Organic compound, charge transport material and organic electroluminescent device PIONEER CORPORATION (JP) 2012-05-01 US disclosed
US-8168307-B2 Organic compound, charge transport material and organic electroluminescent device PIONEER CORPORATION (JP) 2012-05-01 US disclosed
US-20110309338-A1 Materical for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-12-22 US disclosed
US-20110309338-A1 Materical for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-12-22 US disclosed
US-7990046-B2 Material for organic electroluminescent devices and organic electroluminescent devices made by using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-08-02 US disclosed
US-20090021146-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE PIONEER CORPORATION (JP) 2009-01-22 US disclosed
US-20090021146-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE PIONEER CORPORATION (JP) 2009-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090021146-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE SLC25A21, SLCO2A1, OCIAD2 KDM4E 2880/4885L3MBTL1 690/4885ATM 4296/4885
US-20110309338-A1 Materical for organic electroluminescent devices and organic electroluminescent devices made by using the same EML4, BMI1, L1CAM KDM4E 512/4885L3MBTL1 1480/4885ATM 3100/4885
US-20120235129-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICES AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME EED, BMI1, EZH2 KDM4E 624/4885L3MBTL1 1169/4885ATM 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.