Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 5/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059315 | 0.82 | MAPT (0.54) | CDK2MAPK1EGFRCDK1KDM4E | |
| SCHEMBL9828697 | 0.80 | DRD4 (0.56) | CDK2LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL19064636 | 0.78 | SMN1; SMN2 (0.55) | LMNACYP1A2TSHRMAPK1CDK1 | |
| SCHEMBL29829331 | 0.78 | SMN1; SMN2 (0.55) | LMNACYP1A2TSHRMAPK1CDK1 | |
| SCHEMBL15960527 | 0.77 | DPP4 (0.36) | UTS2RTSHRDRD2DRD4DRD3 | |
| 6-Benzylaminopurine SCHEMBL28824679 | 0.77 | LMNA (0.62) | CDK2LMNACYP1A2CYP2D6TSHR | |
| 6-Benzylaminopurine SCHEMBL37357 | 0.77 | LMNA (0.62) | CDK2LMNACYP1A2CYP2D6TSHR | |
| 6-Benzylaminopurine SCHEMBL29772173 | 0.77 | LMNA (0.62) | CDK2LMNACYP1A2CYP2D6TSHR | |
| 6-Benzylaminopurine SCHEMBL11477799 | 0.76 | LMNA (0.61) | CDK2LMNACYP1A2CYP2D6TSHR | |
| 6-Benzylaminopurine SCHEMBL218732 | 0.76 | LMNA (0.61) | CDK2LMNACYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020206363-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ,INC. (US) | 2020-10-08 | — | — | WO | disclosed |
| US-20090306388-A1 | METHOD FOR SUBSTITUTED IH-IMIDAZO[4,5-C] PYRIDINES | PFIZER INC. | 2009-12-10 | — | — | US | disclosed |
| EP-0038569-B1 | DEAZAPURINE NUCLEOSIDES, FORMULATIONS AND PREPARATION THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-01-30 | — | — | EP | disclosed |
| US-4481197-A | ANTIARTHRITIC, ANTIBODY INHIBITORS | BURROUGHS WELLCOME CO. (US) | 1984-11-06 | — | — | US | disclosed |
| EP-0038568-B1 | SYNTHESIS OF DEAZAPURINE NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-07-20 | — | — | EP | disclosed |
| US-4381344-A | Process for producing deoxyribosides using bacterial phosphorylase | BURROUGHS WELLCOME CO. (US) | 1983-04-26 | — | — | US | disclosed |
| US-4347315-A | FORMING 4-SUBSTITUTED 1-B-D-RIBOFURANOSYL-1H-IMIDAZO(4,5-C)PYRIDINES FROM RIBOSE-1-PHOSPHATE | BURROUGHS WELLCOME CO. (US) | 1982-08-31 | — | — | US | disclosed |
| EP-0038568-A1 | Synthesis of deazapurine nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-28 | — | — | EP | disclosed |
| EP-0038569-A2 | Deazapurine nucleosides, formulations and preparation thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306388-A1 | METHOD FOR SUBSTITUTED IH-IMIDAZO[4,5-C] PYRIDINES | PAH, IDH3A, IPO4 | UTS2R 1428/4885CDK2 1031/4885LMNA 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.