Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL4399595 | 0.92 | TDP1 (0.40) | TDP1AKR1B1HSD17B10 | |
| Ethoxycarbonyl Group SCHEMBL17825894 | 0.87 | — | — | |
| Glycerin SCHEMBL28841130 | 0.86 | LMNA (0.43) | AKR1B1 | |
| Ethoxycarbonyl Group SCHEMBL15375848 | 0.82 | TDP1 (0.42) | TDP1HSD17B10 | |
| Ethoxycarbonyl Group SCHEMBL728941 | 0.82 | — | — | |
| Ethoxycarbonyl Group SCHEMBL15376197 | 0.80 | TDP1 (0.43) | TDP1 | |
| Ethoxycarbonyl Group SCHEMBL27704872 | 0.79 | LMNA (0.32) | TDP1 | |
| Ethoxycarbonyl Group SCHEMBL2639322 | 0.79 | — | — | |
| Ethoxycarbonyl Group SCHEMBL3225173 | 0.79 | — | — | |
| Ethoxycarbonyl Group SCHEMBL1332384 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136405-A1 | Method for Decomposition and Removal of Organic Compound in Air Using Platinum as Main Catalysis, Method for Formation of Photocatalytic Article and Photocatalytic Layer, and Photocatalyst | KABUSHIKI KAISHA ZEN WORLD (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1867382-A9 | METHOD FOR DECOMPOSITION AND REMOVAL OF ORGANIC COMPOUND IN AIR USING PLATINUM AS MAIN CATALYSIS, METHOD FOR FORMATION OF PHOTOCATALYTIC ARTICLE AND PHOTOCATALYTIC LAYER, AND PHOTOCATALYST | Kabushiki Kaisha Zen World (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-1867382-A2 | METHOD FOR DECOMPOSITION AND REMOVAL OF ORGANIC COMPOUND IN AIR USING PLATINUM AS MAIN CATALYSIS, METHOD FOR FORMATION OF PHOTOCATALYTIC ARTICLE AND PHOTOCATALYTIC LAYER, AND PHOTOCATALYST | Kabushiki Kaisha Zen World (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-5439998-A | Water and oil repellent | ELF ATOCHEM (FR) | 1995-08-08 | — | — | US | disclosed |