Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethoxycarbonyl Group. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL2639322 | 0.91 | — | — | |
| Ethoxycarbonyl Group SCHEMBL3225173 | 0.90 | — | — | |
| Ethoxycarbonyl Group SCHEMBL1332384 | 0.90 | — | — | |
| Ethoxycarbonyl Group SCHEMBL453 | 0.90 | — | — | |
| Ethoxycarbonyl Group SCHEMBL5306888 | 0.90 | ALDH1A1 (0.38) | — | |
| Ethoxycarbonyl Group SCHEMBL27878173 | 0.88 | — | — | |
| Ethoxycarbonyl Group SCHEMBL28219143 | 0.88 | — | — | |
| Ethoxycarbonyl Group SCHEMBL9718469 | 0.88 | — | — | |
| Ethoxycarbonyl Group SCHEMBL1653351 | 0.87 | — | — | |
| Ethoxycarbonyl Group SCHEMBL5482235 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-213527478-U | Ethanol extraction equipment among ethyl formate | 抚顺顺特化工有限公司 | 2021-06-25 | — | — | CN | disclosed |
| EP-3266450-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | Abraxis BioScience, LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| CN-101579335-B | The preparation of medicament and methods for making and using same thereof | 阿布拉科斯生物科学有限公司 | 2016-08-03 | — | — | CN | disclosed |
| US-20160151325-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | ABRAXIS BIOSCIENCE LLC (US) | 2016-06-02 | — | — | US | disclosed |
| US-20150111960-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | ABRAXIS BIOSCIENCE LLC (US) | 2015-04-23 | — | — | US | disclosed |
| US-20150104521-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | ABRAXIS BIOSCIENCE, LLC (US) | 2015-04-16 | — | — | US | disclosed |
| US-8853260-B2 | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof | ABRAXIS BIOSCIENCE, LLC (US) | 2014-10-07 | — | — | US | disclosed |
| EP-1023050-B1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | ABRAXIS BIOSCIENCE LLC (US) | 2013-09-25 | — | — | EP | disclosed |
| US-20120231082-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | DESAI NEIL P (US) | 2012-09-13 | — | — | US | disclosed |
| US-8137684-B2 | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof | ABRAXIS BIOSCIENCE, LLC (US) | 2012-03-20 | — | — | US | disclosed |
| WO-2003000775-A2 | REACTIVE DILUENT IN MOISTURE CURABLE SYSTEM | CROMPTON CORPORATION (US) | 2003-01-03 | — | — | WO | disclosed |
| US-20020115811-A1 | Reactive diluent in moisture curable system | CROMPTON CORPORATION | 2002-08-22 | — | — | US | disclosed |
| CN-1077093-C | Preparation of polyalcohols | BASF AG (DE) | 2002-01-02 | — | — | CN | disclosed |
| CN-1267214-A | Novel preparation of medicament and preparation and application method thereof | VIVORX PHARMACEUTICALS INC (US) | 2000-09-20 | — | — | CN | disclosed |
| EP-1023050-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | Vivorx Pharmaceuticals, Inc. (US) | 2000-08-02 | — | — | EP | disclosed |
| US-6018074-A | PREPARING A FORMATE CONTAINING POLYALCOHOL BY REACTING AN AQUEOUS SOLUTION OF ALKANAL OR KETONE WITH FORMALDEHYDE USING TERTIARY AMINE CATALYST, WITHOUT HYDROGENATION, USING INCREASING TEMPERATURE GRADIENT IN A THREE-STAGE REACTOR | BASF AKTIENGESELLSHCAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| WO-1999000113-A9 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | VIVORX PHARMACEUTICALS INC (US) | 1999-04-08 | — | — | WO | disclosed |
| WO-1999000113-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | VIVORX PHARMACEUTICALS, INC. (US) | 1999-01-07 | — | — | WO | disclosed |
| CN-1202146-A | Preparation of polyalcohols | BASF AG (DE) | 1998-12-16 | — | — | CN | disclosed |
| US-4628108-A | Production of 2-substituted-1,3-dioxolanes from 1,3-dioxolane and formaldehyde | TEXACO INC. (US) | 1986-12-09 | — | — | US | disclosed |