Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 4/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | BRD2 | P25440 | 2/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440061 | 0.92 | MEN1 (0.41) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL438611 | 0.89 | ALOX5 (0.36) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL440624 | 0.88 | ALOX5 (0.36) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL437601 | 0.88 | ESR1 (0.40) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL437631 | 0.88 | ALOX5 (0.37) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL27449415 | 0.88 | KDM4E (0.33) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL438792 | 0.87 | ALOX5 (0.36) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL440085 | 0.86 | ESR1 (0.41) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL440100 | 0.85 | PRKDC (0.41) | ESR1ESR2KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL440102 | 0.84 | PRKDC (0.39) | ESR1ESR2KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9564597-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-9564597-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20150243899-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150243899-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-08-27 | — | — | US | disclosed |
| US-8993127-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993127-B2 | Fluorene compound, light-emitting element, light-emitting device, electronic device, lighting device, and organic compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20120061714-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-15 | — | — | US | disclosed |
| US-20120061714-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150243899-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | CYP1A1, CYP1B1, DRD1 | ESR1 138/4885ESR2 90/4885KDM4E 3710/4885 |
| US-20120061714-A1 | Fluorene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Organic Compound | CYP1A1, CYP1B1, DRD1 | ESR1 138/4885ESR2 90/4885KDM4E 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.