SCHEMBL4400822

SCHEMBL4400822

Cc1ccc(N(c2ccccc2)c2ccc(C=Cc3ccc(C=Cc4ccc(N(c5ccccc5)c5ccc(C)cc5C)cc4)cc3)cc2)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.44
TRPM8 Q7Z2W7 2/20 0.42
NFE2L2 Q16236 4/20 0.41
CTDSP1 Q9GZU7 1/20 0.39
APP P05067 3/20 0.39
ALOX5 P09917 2/20 0.39
PTGS1 P23219 2/20 0.39
PTGS2 P35354 2/20 0.39
TTR P02766 1/20 0.39
INSR P06213 3/20 0.38
MEN1 O00255 1/20 0.36
S1PR4 O95977 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HPGD P15428 1/20 0.36
S1PR1 P21453 1/20 0.36
MAPK1 P28482 1/20 0.36
CCR6 P51684 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14445153 1.00 RELA (0.44) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL13010108 1.00 RELA (0.44) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL14727230 0.97 RELA (0.49) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL18418091 0.97 RELA (0.49) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL12680417 0.95 RELA (0.47) RELATRPM8NFE2L2CTDSP1ALOX5
SCHEMBL18353269 0.94 RELA (0.44) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL14727235 0.94 RELA (0.44) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL14727229 0.92 RELA (0.45) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL14727239 0.92 RELA (0.45) RELATRPM8NFE2L2CTDSP1APP
SCHEMBL15496768 0.92 RELA (0.45) RELATRPM8NFE2L2CTDSP1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20070248901-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-25 US disclosed
US-20070248901-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-25 US disclosed