SCHEMBL4400839

SCHEMBL4400839

COc1ccc(N(c2ccc(C)cc2)c2ccc(C=Cc3cccc(C=Cc4ccc(N(c5ccc(C)cc5)c5ccc(OC)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 6/20 0.67
NFE2L2 Q16236 4/20 0.56
APP P05067 1/20 0.56
TRPA1 O75762 1/20 0.54
CYP19A1 P11511 2/20 0.49
TUBB1 Q9H4B7 3/20 0.49
TUBB4A P04350 2/20 0.49
TUBB P07437 2/20 0.49
TUBA3C P0DPH7 2/20 0.49
TUBA1B P68363 2/20 0.49
TUBA4A P68366 2/20 0.49
TUBB4B P68371 2/20 0.49
TUBB3 Q13509 2/20 0.49
TUBB2A Q13885 2/20 0.49
TUBB8 Q3ZCM7 2/20 0.49
TUBA3E Q6PEY2 2/20 0.49
TUBA1A Q71U36 2/20 0.49
TUBA1C Q9BQE3 2/20 0.49
TUBB6 Q9BUF5 2/20 0.49
TUBB2B Q9BVA1 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12576253 1.00 RELA (0.67) RELANFE2L2APPTRPA1CYP19A1
SCHEMBL7905696 0.94 RELA (0.71) RELANFE2L2APPTRPA1CYP19A1
SCHEMBL7905694 0.94 RELA (0.71) RELANFE2L2APPTRPA1CYP19A1
SCHEMBL5494942 0.91 RELA (0.82) RELANFE2L2APPTRPA1CYP19A1
SCHEMBL5494946 0.91 RELA (0.82) RELANFE2L2APPTRPA1CYP19A1
SCHEMBL7905688 0.91 RELA (0.66) RELANFE2L2APPCYP19A1TUBB1
SCHEMBL7905686 0.91 RELA (0.66) RELANFE2L2APPCYP19A1TUBB1
SCHEMBL4237316 0.91 RELA (0.66) RELANFE2L2APPCYP19A1TUBB1
SCHEMBL4237317 0.91 RELA (0.66) RELANFE2L2APPCYP19A1TUBB1
SCHEMBL12680433 0.91 RELA (0.68) RELANFE2L2APPTRPA1TUBB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8192905-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed
US-8192905-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
EP-2138899-A1 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor Ricoh Company, Limited (JP) 2009-12-30 EP disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20070248901-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-25 US disclosed
US-20070248901-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-25 US disclosed