SCHEMBL4400932

SCHEMBL4400932

Cc1cccc(P(=O)(c2ccccc2)c2cccc(C)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.46
ACP3 P15309 1/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
MAPT P10636 3/20 0.42
POLB P06746 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HTT P42858 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
RAB9A P51151 4/20 0.42
NPSR1 Q6W5P4 3/20 0.42
TSHR P16473 2/20 0.42
ALOX12 P18054 1/20 0.42
RECQL P46063 1/20 0.41
NPC1 O15118 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HPGD P15428 1/20 0.40
KCNK3 O14649 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31212643 1.00 ACHE (0.46) ACHEACP3LMNASMN1; SMN2MEN1
SCHEMBL31212639 1.00 ACHE (0.46) ACHEACP3LMNASMN1; SMN2MEN1
SCHEMBL260337 1.00 ACHE (0.46) ACHEACP3LMNASMN1; SMN2MEN1
SCHEMBL14339300 0.93 ACHE (0.48) ACHEACP3LMNASMN1; SMN2MEN1
SCHEMBL29968470 0.93 ACHE (0.52) ACHEACP3LMNASMN1; SMN2MEN1
SCHEMBL1003285 0.93 ACHE (0.52) ACHEACP3LMNASMN1; SMN2MEN1
Triphenylphosphine Oxide SCHEMBL29014409 0.86 LMNA (0.58) ACHELMNASMN1; SMN2MEN1KMT2A
SCHEMBL25797628 0.85 NPSR1 (0.44) ACHEACP3LMNASMN1; SMN2MEN1
SCHEMBL25797520 0.85 NPSR1 (0.44) ACHEACP3LMNASMN1; SMN2MEN1
SCHEMBL31212644 0.84 LMNA (0.47) ACHELMNASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675930-B1 NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2018-05-30 EP disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed