SCHEMBL4401064

SCHEMBL4401064

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc(-c3ccc(N(c4cccc(N(c5ccc(-c6ccc(-n7c8ccc(-c9ccccc9)cc8c8cc(-c9ccccc9)ccc87)cc6)cc5)c5cccc6ccccc56)c4)c4cccc5ccccc45)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSPO P30536 2/20 0.35
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SIGMAR1 Q99720 4/20 0.33
NR3C1 P04150 1/20 0.31
HDAC4 P56524 1/20 0.31
PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4401070 1.00 TSPO (0.35) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL10819233 1.00 TSPO (0.35) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL4401067 1.00 TSPO (0.35) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL4400902 1.00 TSPO (0.35) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL10819231 0.99 TSPO (0.34) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL10819212 0.98 TSPO (0.34) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL4400906 0.98 KDM4E (0.33) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL4398142 0.98 KDM4E (0.33) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL20707444 0.98 TSPO (0.36) TSPOKDM4EATML3MBTL1SIGMAR1
SCHEMBL10029867 0.98 TSPO (0.36) TSPOKDM4EATML3MBTL1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8704242-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-8704242-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-20120181523-A1 AROMATIC AMINE COMPOUND, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING AROMATIC AMINE COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-19 US disclosed
US-20120181523-A1 AROMATIC AMINE COMPOUND, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING AROMATIC AMINE COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-19 US disclosed
US-8178885-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 US disclosed
US-8178885-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 US disclosed
US-20100308319-A1 AROMATIC AMINE COMPOUND, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING AROMATIC AMINE COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-12-09 US disclosed
US-20100308319-A1 AROMATIC AMINE COMPOUND, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING AROMATIC AMINE COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-12-09 US disclosed
US-7795449-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-09-14 US disclosed
US-7795449-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-09-14 US disclosed
US-20080312454-A1 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-12-18 US disclosed
US-7442803-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-28 US disclosed
US-7442803-B2 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-28 US disclosed
US-20070096639-A1 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-05-03 US disclosed
US-20070096639-A1 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312454-A1 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound TYR, HEATR1, HSF1 TSPO 3463/4885KDM4E 1642/4885ATM 295/4885
US-20070096639-A1 Aromatic amine compound, and light emitting element, light emitting device, and electronic device using aromatic amine compound TYR, HEATR1, HSF1 TSPO 3463/4885KDM4E 1642/4885ATM 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.