Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400953 | 0.84 | ESR2 (0.73) | ESR2ESR1SMN1; SMN2HTR3EHTR3B | |
| SCHEMBL11774153 | 0.81 | CYP2D6 (0.66) | SMN1; SMN2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11774159 | 0.81 | CYP2D6 (0.66) | SMN1; SMN2HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL11769769 | 0.80 | CYP2D6 (0.64) | SMN1; SMN2HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL11769765 | 0.80 | CYP2D6 (0.64) | SMN1; SMN2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20198257 | 0.80 | ESR2 (0.66) | ESR2ESR1SMN1; SMN2HTR3EHTR3B | |
| SCHEMBL25693071 | 0.80 | ESR2 (0.66) | ESR2ESR1SMN1; SMN2HTR3EHTR3B | |
| SCHEMBL4450591 | 0.79 | ESR2 (0.74) | ESR2ESR1HTR3EHTR3BHTR3A | |
| SCHEMBL12336909 | 0.78 | ESR2 (0.69) | ESR2ESR1HTR3EHTR3BHTR3A | |
| SCHEMBL434736 | 0.78 | ALDH1A1 (0.52) | ESR2ESR1SMN1; SMN2POLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20100102305-A1 | MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100102305-A1 | MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-7659540-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2010-02-09 | — | — | US | disclosed |
| US-7659540-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20070080343-A1 | New materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070080343-A1 | New materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |