Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398747 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL13897067 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL10388301 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL14213298 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL27009939 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL12228739 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL18901456 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL5403101 | 0.74 | ALDH1A1 (0.49) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL17107938 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDPOLBKMT2AHSD17B10 | |
| SCHEMBL4402661 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDPOLBKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | DNMT3B, HMBS, MMAB | ALDH1A1 454/4885HPGD 463/4885POLB 65/4885 |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | MMAB, DNMT3B, RHEB | ALDH1A1 4132/4885HPGD 3718/4885POLB 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.