Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758335 | 1.00 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| Toluene SCHEMBL8772784 | 0.87 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1402481 | 0.81 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13066221 | 0.80 | CA1 (0.50) | CA12CA1CA2CA7CA9 | |
| 1,2,4-Trimethoxybenzene SCHEMBL27777905 | 0.77 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| 1,2,4-Trimethoxybenzene SCHEMBL29350371 | 0.77 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| 1,2,4-Trimethoxybenzene SCHEMBL481491 | 0.77 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1402590 | 0.77 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9188740 | 0.76 | ACHE (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL32675289 | 0.76 | CA12 (0.46) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106833406-A | A kind of high refractive index nano inorganic matter hydridization photovoltaic encapsulation material | 杭州福斯特光伏材料股份有限公司 | 2017-06-13 | — | — | CN | claimed |
| US-9487553-B2 | Boranophosphate analogues of cyclic nucleotides | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2016-11-08 | — | — | US | claimed |
| EP-2691403-B1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INST FORSCHUNGSLABOR UND BIOCHEMICA VERTRIEB GMBH (DE) | 2016-05-18 | — | — | EP | claimed |
| EP-1511757-B1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | UNIV MEDISCH CENTRUM UTRECHT (NL) | 2015-11-04 | — | — | EP | claimed |
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2014-03-27 | — | — | US | claimed |
| EP-2691403-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG Life Science Institute Forschungslabor Und Biochemica-Vertrieb GmbH (DE) | 2014-02-05 | — | — | EP | claimed |
| WO-2012130829-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| US-7906491-B2 | Compounds for modulating the activity of exchange proteins directly activated by cAMP (Epacs) | UNIVISITAIR MEDISCH CENTRUM UTRECHT (NL) | 2011-03-15 | — | — | US | claimed |
| WO-2007006544-A2 | CYCLIC ADENOSINE MONOPHOSPHATE COMPOUNDS FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS | VRIJE UNIVERSITEIT BRUSSEL (BE) | 2007-01-18 | — | — | WO | claimed |
| CN-1260210-C | 2,5-dimethoxy-4-ethyl benzaldehyde sulfide and preparation process and use thereof | UNIV WUHAN (CN) | 2006-06-21 | — | — | CN | claimed |
| CN-1228320-C | 2,5-dimethoxy-4-ethyl sulfide-beta-nitrostyrolene and preparation process and use thereof | UNIV WUHAN (CN) | 2005-11-23 | — | — | CN | claimed |
| CN-1206214-C | 2,5-dimethoxy phenylmercaptan and synthesis process and use thereof | UNIV WUHAN (CN) | 2005-06-15 | — | — | CN | claimed |
| CN-1193012-C | 2,5-dimethoxy-4-ethyl phenethyl amine sulfide hydrochloride and preparation process and use thereof | UNIV WUHAN (CN) | 2005-03-16 | — | — | CN | claimed |
| EP-1511757-A1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | Kylix B.V. (NL) | 2005-03-09 | — | — | EP | claimed |
| WO-2003104250-A1 | NEW COMPOUNDS FOR MODULATING THE ACTIVITY OF EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPACS) | KYLIX, B. V. (NL) | 2003-12-18 | — | — | WO | claimed |
| CN-1434030-A | 2,5-dimethoxy ethyl phenyl sulfide and synthesis method and use thereof | UNIV WUHAN (CN) | 2003-08-06 | — | — | CN | claimed |
| CN-1434032-A | 2,5-dimethoxy phenylmercaptan and synthesis process and use thereof | UNIV WUHAN (CN) | 2003-08-06 | — | — | CN | claimed |
| CN-1434029-A | 2,5-dimethoxy-4-ethyl benzaldehyde sulfide and preparation process and use thereof | UNIV WUHAN (CN) | 2003-08-06 | — | — | CN | claimed |
| CN-1434031-A | 2,5-dimethoxy-4-ethyl sulfide-beta-nitrostyrolene and preparation process and use thereof | UNIV WUHAN (CN) | 2003-08-06 | — | — | CN | claimed |
| CN-1434033-A | 2,5-dimethoxy-4-ethyl phenethyl amine sulfide hydrochloride and preparation process and use thereof | UNIV WUHAN (CN) | 2003-08-06 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | NT5C2, NT5E, ENPP3 | CA12 2522/4885CA1 2453/4885CA2 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.