Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565247 | 0.85 | TSHR (0.48) | HPGDESR1HTTMAPTKDM4E | |
| SCHEMBL4401114 | 0.85 | POLB (0.50) | HPGDHTTMAPTKDM4EPOLB | |
| SCHEMBL25797392 | 0.85 | HPGD (0.48) | HPGDESR1HTTMAPTKDM4E | |
| SCHEMBL25797505 | 0.79 | ESR1 (0.54) | HPGDESR1MEN1KMT2ACA2 | |
| SCHEMBL25797391 | 0.79 | ESR1 (0.54) | HPGDESR1MEN1KMT2ACA2 | |
| SCHEMBL3787009 | 0.79 | ESR1 (0.54) | HPGDESR1MEN1KMT2ACA2 | |
| SCHEMBL30085199 | 0.79 | ESR1 (0.54) | HPGDESR1MEN1KMT2ACA2 | |
| SCHEMBL4403108 | 0.77 | HPGD (0.41) | HPGDHTTMEN1KMT2AHCRTR1 | |
| SCHEMBL22695474 | 0.76 | MEN1 (0.52) | HPGDHTTMAPTKDM4EMEN1 | |
| SCHEMBL967941 | 0.75 | LMNA (0.48) | HTTMEN1KMT2AHCRTR1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20100102305-A1 | MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-7659540-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20070080343-A1 | New materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |