SCHEMBL4401114

SCHEMBL4401114

Cc1ccc(C)c(P(=O)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HTT P42858 2/20 0.42
KMT2A Q03164 6/20 0.41
MEN1 O00255 4/20 0.41
HCRTR1 O43613 1/20 0.41
HPGD P15428 3/20 0.41
NPSR1 Q6W5P4 2/20 0.40
APOBEC3A P31941 1/20 0.38
CASP6 P55212 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4401222 0.85 HPGD (0.48) POLBMAPTKDM4EHTTKMT2A
SCHEMBL4403134 0.84 POLB (0.47) POLBMAPTKDM4EHTTKMT2A
SCHEMBL9001542 0.83 TDP1 (0.42) KDM4EHTTKMT2AMEN1HCRTR1
SCHEMBL15565247 0.81 TSHR (0.48) POLBMAPTKDM4EHTTKMT2A
SCHEMBL25797515 0.81 POLB (0.50) POLBMAPTKDM4EHTTKMT2A
SCHEMBL25797516 0.81 POLB (0.50) POLBMAPTKDM4EHTTKMT2A
SCHEMBL25797520 0.80 NPSR1 (0.44) POLBMAPTKDM4EHTTKMT2A
SCHEMBL25797628 0.80 NPSR1 (0.44) POLBMAPTKDM4EHTTKMT2A
SCHEMBL16653023 0.80 POLB (0.45) POLBMAPTKDM4EHTTKMT2A
SCHEMBL471978 0.79 NPSR1 (0.49) POLBMAPTKDM4EHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2880041-B1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL SCIENT IND RES (IN) 2018-10-10 EP disclosed
US-9200018-B2 Process for preparation of aryl phosphorous compounds COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-01 US disclosed
US-9200018-B2 Process for preparation of aryl phosphorous compounds COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-01 US disclosed
US-9200018-B2 Process for preparation of aryl phosphorous compounds COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-01 US disclosed
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-30 US disclosed
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-30 US disclosed
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-30 US disclosed
EP-2880041-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS Council of Scientific & Industrial Research (IN) 2015-06-10 EP disclosed
WO-2014024212-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-02-13 WO disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS PFAS, PAICS, INPP5B POLB 1492/4885MAPT 2473/4885KDM4E 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.