Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298673 | 0.89 | DGAT1 (0.72) | DGAT1EPHX2 | |
| SCHEMBL4305430 | 0.79 | DGAT1 (0.79) | DGAT1EPHX2 | |
| SCHEMBL4406451 | 0.76 | DGAT1 (0.52) | DGAT1EPHX2PDCD1CD274SCN9A | |
| SCHEMBL4407981 | 0.74 | DGAT1 (0.47) | DGAT1EPHX2PDCD1CD274SCN9A | |
| SCHEMBL4298316 | 0.73 | DGAT1 (1.00) | DGAT1EPHX2 | |
| SCHEMBL4297509 | 0.72 | DGAT1 (0.79) | DGAT1EPHX2SCN9A | |
| SCHEMBL4300131 | 0.72 | DGAT1 (0.81) | DGAT1EPHX2 | |
| SCHEMBL4293202 | 0.72 | DGAT1 (0.77) | DGAT1EPHX2 | |
| SCHEMBL4300240 | 0.72 | DGAT1 (0.77) | DGAT1EPHX2 | |
| SCHEMBL4407117 | 0.71 | DGAT1 (0.49) | DGAT1EPHX2PDCD1CD274SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |