Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | MASP2 | O00187 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL20495955 | 0.90 | LMNA (0.42) | LMNACASP1CYP1A2SMN1; SMN2PDPK1 | |
| Sulfuric Acid SCHEMBL27603434 | 0.85 | KDM4E (0.42) | LMNACASP1CYP1A2PDPK1 | |
| Hydrogen Peroxide SCHEMBL6095945 | 0.79 | CYP1A2 (0.50) | LMNACASP1CYP1A2POLBADORA3 | |
| Hydroxyamine SCHEMBL8577072 | 0.79 | LMNA (0.47) | LMNACASP1CYP1A2POLBADORA3 | |
| SCHEMBL175612 | 0.78 | CASP1 (0.50) | LMNACASP1CYP1A2POLBADORA3 | |
| SCHEMBL9583239 | 0.78 | CASP1 (0.50) | LMNACASP1CYP1A2POLBADORA3 | |
| SCHEMBL9579151 | 0.78 | CASP1 (0.50) | LMNACASP1CYP1A2POLBADORA3 | |
| SCHEMBL8465809 | 0.78 | CASP1 (0.50) | LMNACASP1CYP1A2POLBADORA3 | |
| SCHEMBL29900242 | 0.78 | — | — | |
| SCHEMBL29876207 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111560166-A | Halogen-free flame-retardant polyamide thermoplastic elastomer composition and preparation method thereof | 沧州旭阳科技有限公司 | 2020-08-21 | — | — | CN | claimed |
| EP-1787307-B1 | ARC-EXTINGUISHING COMPOSITION AND ARTICLES MANUFACTURED THEREFROM | S & C ELECTRIC CO (US) | 2015-01-28 | — | — | EP | claimed |
| CN-118183815-A | Method for preparing calcium peroxide based on dicyandiamide waste residues and application thereof | 河西学院 | 2024-06-14 | — | — | CN | disclosed |
| CN-112980207-A | Wood-plastic composite section and preparation method thereof | 浙江亚厦装饰股份有限公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-2096711-B1 | SHEET BODY FOR IMPROVING COMMUNICATION, ANTENNA DEVICE PROVIDED WITH SUCH SHEET BODY AND ELECTRONIC INFORMATION TRANSMITTING APPARATUS | NITTA CORP (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-8564472-B2 | Sheet member for improving communication, and antenna device and electronic information transmitting apparatus provided therewith | NITTA CORPORATION (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8101330-B2 | Two component developer and image forming method | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8039184-B2 | Two-component developer | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-7914964-B2 | Both-sided image forming method | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2011-03-29 | — | — | US | disclosed |
| CN-1926933-B | Electromagnetic wave absorbent | NITTA CORP | 2010-12-08 | — | — | CN | disclosed |
| CN-101069461-B | Electromagnetic interference suppressing body, antenna device, and electronic information transmission device | NITTA CORP | 2010-12-08 | — | — | CN | disclosed |
| CN-101069461-A | Electromagnetic interference suppressing body, antenna device, and electronic information transmission device | NITTA CORP (JP) | 2007-11-07 | — | — | CN | disclosed |
| US-20070252771-A1 | Electromagnetic Interference Suppressor, Antenna Device and Electronic Information Transmitting Apparatus | NITTA CORPORATION (JP) | 2007-11-01 | — | — | US | disclosed |
| CN-101032198-A | Electromagnetic wave absorber | NITTA CORP (JP) | 2007-09-05 | — | — | CN | disclosed |
| EP-1819211-A1 | ELECTROMAGNETIC INTERFERENCE INHIBITOR, ANTENNA DEVICE AND ELECTRONIC COMMUNICATION APPARATUS | Nitta Corporation (JP) | 2007-08-15 | — | — | EP | disclosed |
| EP-1806961-A1 | ELECTROMAGNETIC WAVE ABSORBER | Nitta Corporation (JP) | 2007-07-11 | — | — | EP | disclosed |
| CN-1926933-A | Electromagnetic wave absorbent | NITTA CORP (JP) | 2007-03-07 | — | — | CN | disclosed |
| EP-1722618-A1 | ELECTROMAGNETIC WAVE ABSORBER | Nitta Corporation (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-6136200-A | DOSING WATER FROM WASTE WATER SYSTEM WITHIN AN DETACKFYING AMOUNT OF INORGANIC AND ORGANIC POLYMER ADDUCT SYSTEM COMPRISING CATIONIC POLYMER UNIT, ANIONIC POLYER UNIT, ACRYLAMIDE UNITS AND ALUMINUM SULFATE OCTAHYDRATE | POLYMER RESEARCH CORPORATION (US) | 2000-10-24 | — | — | US | disclosed |
| US-5294352-A | Polymer alloy | WALDMANN JOHN J (US) | 1994-03-15 | — | — | US | disclosed |