Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818347 | 0.90 | AURKA (0.50) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL6280639 | 0.88 | AURKA (0.56) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL17121328 | 0.88 | AURKA (0.56) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL338441 | 0.88 | AURKA (0.46) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL31229289 | 0.88 | AURKA (0.46) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL30218795 | 0.88 | AURKA (0.42) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL3822788 | 0.88 | AURKA (0.42) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL29384070 | 0.88 | AURKA (0.46) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL2730921 | 0.86 | AURKA (0.50) | AURKAAURKBALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL572527 | 0.86 | AURKA (0.50) | AURKAAURKBALDH1A1HSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445292-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120107942-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2012-05-03 | — | — | US | disclosed |