SCHEMBL338441

SCHEMBL338441

Nc1cc(S(=O)(=O)O)c2ccc3c(S(=O)(=O)O)cc(S(=O)(=O)O)c4ccc1c2c43

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.46
AURKB Q96GD4 1/20 0.46
ALDH1A1 P00352 7/20 0.44
HSD17B10 Q99714 5/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CASP6 P55212 2/20 0.44
CYP1A2 P05177 1/20 0.44
TTR P02766 1/20 0.44
MEN1 O00255 3/20 0.43
MAPT P10636 3/20 0.43
THRB P10828 3/20 0.43
HPGD P15428 3/20 0.43
RECQL P46063 3/20 0.43
BLM P54132 3/20 0.43
KMT2A Q03164 3/20 0.43
TSHR P16473 3/20 0.43
KDM4E B2RXH2 2/20 0.43
TP53 P04637 2/20 0.43
CYP3A4 P08684 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31229289 1.00 AURKA (0.46) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL29384070 1.00 AURKA (0.46) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL26638157 0.98 AURKA (0.45) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL592094 0.98 AURKA (0.45) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL592096 0.98 ALDH1A1 (0.47) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL22280861 0.91 AURKA (0.41) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL6818347 0.91 AURKA (0.50) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL2730921 0.91 AURKA (0.50) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL3260824 0.89 AURKA (0.49) AURKAAURKBALDH1A1HSD17B10CYP2C9
SCHEMBL4402089 0.88 AURKA (0.47) AURKAAURKBALDH1A1HSD17B10CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 887 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679077-A1 OLIGOSACCHARIDE CHAIN-BASED DETECTION REAGENT FOR DETECTING INTESTINAL CANCER, PREPARATION METHOD, AND USE Xiansida Nanjing Biotechnology Co., Ltd. (CN) 2026-01-14 EP claimed
US-12510547-B2 Sample preparation by temperature gradient denaturation and scale-up for deep n-glycomic analysis of serum for capillary electrophoresis and CE-ESI-MS DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) 2025-12-30 US claimed
EP-3737753-B1 USE OF TRI- AND TETRA-HYDROXYL QUATERNARY AMMONIUM COMPOUNDS AS RESOLVING AGENTS FOR ELECTROPHORESITIC SEPARATIONS AGILENT TECHNOLOGIES INC (US) 2025-10-22 EP claimed
US-20250290918-A1 METHODS FOR ASSESSING CELL SURFACE GLYCOSYLATION JUNO THERAPEUTICS, INC. (US) 2025-09-18 US claimed
EP-3684941-B1 USE OF POLYAMINES AS RESOLVING AGENTS FOR CAPILLARY ELECTROPHORESIS OF LABELED GLYCANS USING GELS AGILENT TECHNOLOGIES INC (US) 2025-05-14 EP claimed
US-12286574-B2 Manipulating hydrophilicity of conventional dye molecules for tracer applications SAUDI ARABIAN OIL COMPANY (SA) 2025-04-29 US claimed
WO-2025070814-A1 SUGAR CHAIN PREPARATION METHOD AND SUGAR CHAIN ANALYSIS METHOD 住友ベークライト株式会社 2025-04-03 WO claimed
US-12210027-B2 Glycan sample preparation BECKMAN COULTER, INC. (US) 2025-01-28 US claimed
WO-2024183385-A1 OLIGOSACCHARIDE CHAIN-BASED DETECTION REAGENT FOR DETECTING INTESTINAL CANCER, PREPARATION METHOD, AND USE 先思达(南京)生物科技有限公司 2024-09-12 WO claimed
WO-2024183386-A1 OLIGOSACCHARIDE CHAIN-BASED DETECTION REAGENT FOR DETECTING PROSTATE CANCER, PREPARATION METHOD AND USE 先思达(南京)生物科技有限公司 2024-09-12 WO claimed
WO-2001092890-A1 METHOD FOR THE ANALYSIS OF PICOMOLE AMOUNTS OF CARBOHYDRATES VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) 2001-12-06 WO claimed
US-5964999-A Methods for profiling oligosaccharides released from glycoproteins BECKMAN INSTRUMENTS, INC. (US) 1999-10-12 US claimed
EP-0867722-A2 Method for measuring interaction between sugar and target TAKARA SHUZO CO. LTD. (JP) 1998-09-30 EP claimed
EP-0763197-A1 METHOD AND APPARATUS FOR AUTOMATED CARBOHYDRATE MAPPING AND SEQUENCING PERKIN-ELMER CORPORATION (US) 1997-03-19 EP claimed
WO-1995033989-A1 METHOD AND APPARATUS FOR AUTOMATED CARBOHYDRATE MAPPING AND SEQUENCING PERKIN-ELMER CORPORATION (US) 1995-12-14 WO claimed
EP-0397641-B1 Method for quantitatively determining a chemical parameter of a sample AVL MEDICAL INSTR AG (CH) 1995-07-05 EP claimed
US-5284558-A Treating a labelled and charged oligosaccharide with an exoglycosidase to remove the non-reducing monosaccharide; correlating the enzyme specificity with electrophoretic data UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1994-02-08 US claimed
US-5232858-A Selecting substances such that the emission spectrum of the fluorescent overlaps the absorption spectrum of the chromogen; absorption maximum shifted by analyte; fluorescence decay reduced by energy transfer AVL MEDICAL INSTRUMENTS AG (CH) 1993-08-03 US claimed
WO-1992002816-A1 ELECTROPHORESIS-BASED SEQUENCING OF OLIGOSACCHARIDES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1992-02-20 WO claimed
EP-0397641-A2 Method for quantitatively determining a chemical parameter of a sample AVL Medical Instruments AG (CH) 1990-11-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12510547-B2 Sample preparation by temperature gradient denaturation and scale-up for deep n-glycomic analysis of serum for capillary electrophoresis and CE-ESI-MS ANPEP, FUCA2, NPEPPS AURKA 1772/4885AURKB 1897/4885ALDH1A1 2398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.