Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572527 | 0.96 | AURKA (0.50) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL29393812 | 0.96 | AURKA (0.50) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL28560090 | 0.95 | AURKA (0.49) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL2730921 | 0.93 | AURKA (0.50) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL31229289 | 0.91 | AURKA (0.46) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL29384070 | 0.91 | AURKA (0.46) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL338441 | 0.91 | AURKA (0.46) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL4402089 | 0.90 | AURKA (0.47) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL11524521 | 0.89 | AURKA (0.54) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL592094 | 0.89 | AURKA (0.45) | AURKAAURKBTTRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906432-B1 | RECOMBINANT ALPHA-2,3-SIALYLTRANSFERASES AND THEIR USES | CA NAT RESEARCH COUNCIL (CA) | 2004-06-09 | — | — | EP | disclosed |
| US-6210933-B1 | AMINO ACID SEQUENCE; FOR ADDING SIALIC ACIDS TO GLYCOPROTEINS, GLYCOLIPIDS, AND OTHER ACCEPTOR MOLECULES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2001-04-03 | — | — | US | disclosed |
| US-6096529-A | FROM NEISSERIA SPECIES; FOR SYNTHESIS OF DESIRED OLIGOSACCHARIDES WITH BIOLOGICAL ACTIVITY | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2000-08-01 | — | — | US | disclosed |
| EP-0906432-A1 | RECOMBINANT ALPHA-2,3-SIALYLTRANSFERASES AND THEIR USES | National Research Council of Canada (CA) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997047749-A1 | RECOMBINANT α-2,3-SIALYLTRANSFERASES AND THEIR USES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1997-12-18 | — | — | WO | disclosed |