Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.77 |
| ▸ | THRB | P10828 | 8/20 | 0.77 |
| ▸ | BLM | P54132 | 7/20 | 0.77 |
| ▸ | RECQL | P46063 | 6/20 | 0.77 |
| ▸ | TOP2A | P11388 | 5/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 4/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.77 |
| ▸ | FYN | P06241 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620307 | 0.95 | MEN1 (0.79) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL9178542 | 0.94 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL30239106 | 0.94 | MEN1 (0.77) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL26961130 | 0.94 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL27393066 | 0.93 | MEN1 (0.77) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL25228806 | 0.93 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL20307182 | 0.93 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL10014019 | 0.93 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL30465123 | 0.93 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL16622415 | 0.93 | MEN1 (0.80) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720575-B1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS INC (US) | 2015-05-20 | — | — | EP | disclosed |
| US-8158573-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20120063993-A1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-7405320-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| EP-1720575-A2 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | Immunomedics Inc. (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005077071-A2 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS, INC. (US) | 2005-08-25 | — | — | WO | disclosed |
| US-20050002945-A1 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050002945-A1 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | TST, GLUL, TGM3 | MEN1 1321/4885KMT2A 1001/4885THRB 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.