SCHEMBL4402172

SCHEMBL4402172

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=Cc3cccc(C=Cc4ccc(N(c5ccc(C)cc5)c5ccc(C)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.59
APP P05067 5/20 0.50
RELA Q04206 4/20 0.47
ALOX5 P09917 1/20 0.44
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
CYP19A1 P11511 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4405003 0.95 NFE2L2 (0.54) NFE2L2APPRELACYP19A1
SCHEMBL13898807 0.95 NFE2L2 (0.54) NFE2L2APPRELACYP19A1
SCHEMBL16790481 0.93 NFE2L2 (0.56) NFE2L2APPRELAALOX5PTGS1
SCHEMBL16790471 0.93 NFE2L2 (0.56) NFE2L2APPRELAALOX5PTGS1
SCHEMBL19863795 0.93 RELA (0.57) NFE2L2APPRELAALOX5PTGS1
SCHEMBL14526441 0.93 NFE2L2 (0.56) NFE2L2APPRELAALOX5PTGS1
SCHEMBL9395024 0.93 NFE2L2 (0.56) NFE2L2APPRELAALOX5PTGS1
SCHEMBL9395031 0.93 NFE2L2 (0.56) NFE2L2APPRELAALOX5PTGS1
SCHEMBL10039798 0.90 NFE2L2 (0.50) NFE2L2APPRELAALOX5PTGS1
SCHEMBL13308456 0.90 NFE2L2 (0.50) NFE2L2APPRELAALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8192905-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090058270-A1 PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-05 US disclosed
US-20090058270-A1 PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-05 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
EP-1926159-A1 ASYMMETRIC FLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 2008-05-28 EP disclosed
US-20070248901-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-25 US disclosed
US-20070248901-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-25 US disclosed