SCHEMBL44023

SCHEMBL44023

O=C(O)CC1CNCCC(O)C1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 4/20 0.69
SLC6A11 P48066 4/20 0.69
SLC6A13 Q9NSD5 4/20 0.69
GABRA5 P31644 3/20 0.69
GABRB2 P47870 3/20 0.69
SLC6A12 P48065 3/20 0.69
GABRA1 P14867 2/20 0.69
GABRA4 P48169 2/20 0.69
GABRR1 P24046 1/20 0.69
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CPN1 P15169 1/20 0.35
CPB2 Q96IY4 1/20 0.35
EPHX1 P07099 1/20 0.35
DPP4 P27487 1/20 0.34
TSHR P16473 2/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24478321 0.82
SCHEMBL374930 0.82
SCHEMBL2450833 0.82
Hydrochloric Acid SCHEMBL21774701 0.80 SLC6A1 (0.96) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL21774704 0.80 SLC6A1 (0.96) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Hydrochloric Acid SCHEMBL22655757 0.80 SLC6A1 (0.96) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
SCHEMBL30299155 0.78 SLC6A11 (0.75) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
SCHEMBL2918774 0.78 SLC6A11 (0.75) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
Acetic Acid SCHEMBL8859076 0.77 SLC6A1 (0.88) SLC6A1SLC6A11SLC6A13GABRA5GABRB2
SCHEMBL30793947 0.76 SLC6A1 (0.41) SLC6A1SLC6A11SLC6A13GABRA5GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011151436-A2 NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM EUROSCREEN S.A. (BE) 2011-12-08 WO claimed