⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL9077806 | 1.00 | ALDH1A1 (0.67) | — | |
| Methylene Chloride SCHEMBL27973738 | 0.96 | — | — | |
| Tetrahydrofuran SCHEMBL6848959 | 0.96 | — | — | |
| Methylene Chloride SCHEMBL537651 | 0.96 | ALDH1A1 (0.61) | — | |
| Cyclohexane SCHEMBL1742381 | 0.96 | ALDH1A1 (0.61) | — | |
| Dioxane SCHEMBL23167499 | 0.93 | ALDH1A1 (0.57) | — | |
| Tetrahydrofuran SCHEMBL2395526 | 0.89 | ALDH1A1 (0.53) | — | |
| Tetrahydrofuran SCHEMBL5106977 | 0.88 | — | — | |
| Tetrahydrofuran SCHEMBL6732479 | 0.87 | ALDH1A1 (0.50) | — | |
| Tetrahydrofuran SCHEMBL29225325 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1084 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946155-A | Metal complex, preparation method and application thereof, catalyst and application thereof and preparation method of asymmetric pinacol | 中国石油化工股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117752615-A | Nanoparticle based on chitosan-lecithin loaded curcumin and preparation method thereof | 广西大学 | 2024-03-26 | — | — | CN | claimed |
| US-20230125064-A2 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR,PREPARATION METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2023-04-20 | — | — | US | claimed |
| EP-3532673-B1 | DEFLECTION MEMBER FOR MAKING FIBROUS STRUCTURES | PROCTER & GAMBLE (US) | 2022-11-02 | — | — | EP | claimed |
| US-20220194934-A1 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR,PREPARATION METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2022-06-23 | — | — | US | claimed |
| EP-3939978-A1 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Transthera Sciences (Nanjing), Inc. (CN) | 2022-01-19 | — | — | EP | claimed |
| CN-111689958-B | Crystal forms of phosphodiesterase inhibitors, preparation method and uses thereof | 南京药捷安康生物科技有限公司 | 2021-11-19 | — | — | CN | claimed |
| CN-113402411-A | Oxidation reaction-based synthesis method of propyzamide | 深圳市谦陌通辰实验有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-110327856-B | Preparation method of microcapsule with meteorite crater structure | 武汉中科先进技术研究院有限公司 | 2021-08-10 | — | — | CN | claimed |
| US-20210188856-A1 | CRYSTAL FORM OF HYDROCHLORIDE OF PYRAZOLOHETEROARYL DERIVATIVE AND PREPARATION METHOD | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD (CN) | 2021-06-24 | — | — | US | claimed |
| US-20090069563-A1 | Rosuvastatin intermediates and their preparation | TEVA PHARMACEUTICALS USA, INC. | 2009-03-12 | — | — | US | claimed |
| WO-2009009152-A1 | ROSUVASTATIN INTERMEDIATES AND THEIR PREPARATION | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-01-15 | — | — | WO | claimed |
| WO-2008051489-A2 | SALT FORMS OF SUBSTITUTED BENZOTHIENYL COMPOUNDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-05-02 | — | — | WO | claimed |
| US-20080097110-A1 | Salt forms of substituted benzothienyl compounds | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-04-24 | — | — | US | claimed |
| US-7169460-B1 | Multilayer; core of thermoplastic resin and wood filler, print layer and protective coatings; is not susceptible to damage caused by moisture | MANNINGTON MILLS, INC. (US) | 2007-01-30 | — | — | US | claimed |
| US-20050234251-A1 | Process and new intermediates for the preparation of steroids with a progestogen activity | POLI INDUSTRIA CHEMICA SPA (IT) | 2005-10-20 | — | — | US | claimed |
| US-6800142-B1 | Method for removing photoresist and post-etch residue using activated peroxide followed by supercritical fluid treatment | NOVELLUS SYSTEMS, INC. | 2004-10-05 | — | — | US | claimed |
| US-5425854-A | Separation of methylene chloride from tetrahydrofuran by extractive distillation | Berg, Lloyd (US) | 1995-06-20 | — | — | US | claimed |
| EP-0199490-A1 | Penem derivatives | FARMITALIA CARLO ERBA S.r.l. (IT) | 1986-10-29 | — | — | EP | claimed |
| US-4344883-A | Production of N-chlorosulfinylcarbamate esters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1982-08-17 | — | — | US | claimed |