Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.45 |
| ▸ | OXTR | P30559 | 8/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148592 | 0.87 | HTR6 (0.49) | HTR6OXTRCTSSCHRM1DRD2 | |
| SCHEMBL3153461 | 0.78 | HTR6 (0.66) | HTR6OXTR | |
| SCHEMBL3152642 | 0.78 | HTR6 (0.55) | HTR6OXTRCTSSCHRM1DRD2 | |
| SCHEMBL3152985 | 0.78 | HTR6 (0.56) | HTR6 | |
| SCHEMBL3157767 | 0.77 | HTR6 (0.54) | HTR6 | |
| SCHEMBL3152690 | 0.77 | HTR6 (0.49) | HTR6OXTR | |
| SCHEMBL5697915 | 0.77 | HTR6 (0.37) | HTR6 | |
| SCHEMBL5781747 | 0.77 | CHRM1 (0.36) | CHRM1DRD2 | |
| SCHEMBL3144598 | 0.77 | HTR6 (0.52) | HTR6CTSSCHRM1DRD2 | |
| SCHEMBL3148130 | 0.76 | MBTD1 (0.56) | HTR6OXTRCTSSCHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |