Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404504 | 0.89 | MEN1 (0.45) | MEN1KMT2AMAP2K4MAPK1KDM4E | |
| SCHEMBL30189262 | 0.84 | MAP2K4 (0.47) | MAP2K4MAPK1KDM4EACACBACACA | |
| SCHEMBL2671667 | 0.84 | MAP2K4 (0.47) | MAP2K4MAPK1KDM4EACACBACACA | |
| SCHEMBL25139495 | 0.81 | ABL1 (0.51) | — | |
| SCHEMBL4137466 | 0.80 | ACACB (0.44) | MAP2K4MAPK1ACACBACACARAB9A | |
| SCHEMBL4407779 | 0.77 | GSK3B (0.47) | — | |
| SCHEMBL2300578 | 0.74 | MAPK1 (0.42) | MAPK1KDM4E | |
| SCHEMBL2300575 | 0.74 | MAPK1 (0.42) | MAPK1KDM4E | |
| SCHEMBL14038753 | 0.72 | KDR (0.41) | MAPK1 | |
| SCHEMBL2671776 | 0.72 | MAP2K4 (0.50) | MAP2K4MAPK1KDM4EACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |