Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 7/20 | 0.46 |
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PYGB | P11216 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589158 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL9348641 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL4606854 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL7927733 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL1820900 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL23026283 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL7919319 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL8614599 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL15353147 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB | |
| SCHEMBL8586429 | 1.00 | LGALS8 (0.46) | LGALS8OGASLC2A1MAPK1PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4481375-A2 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | F. Hoffmann-La Roche AG (CH) | 2024-12-25 | — | — | EP | disclosed |
| EP-3523639-B1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | HOFFMANN LA ROCHE (CH) | 2024-12-18 | — | — | EP | disclosed |
| US-20240327892-A1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | ROCHE DIABETES CARE, INC. | 2024-10-03 | — | — | US | disclosed |
| US-12024735-B2 | Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same | ROCHE DIABETES CARE, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| EP-4152003-A1 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS | Roche Diabetes Care GmbH (DE) | 2023-03-22 | — | — | EP | disclosed |
| EP-3757574-B1 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS | ROCHE DIABETES CARE GMBH (DE) | 2022-12-07 | — | — | EP | disclosed |
| US-20220098636-A1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | ROCHE DIABETES CARE, INC. (US) | 2022-03-31 | — | — | US | disclosed |
| US-11230727-B2 | Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same | ROCHE DIABETES CARE, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| US-11220674-B2 | Stabilization of dehydrogenases with stable coenzymes | ROCHE DIABETES CARE, INC. (US) | 2022-01-11 | — | — | US | disclosed |
| EP-3757574-A1 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS | Roche Diabetes Care GmbH (DE) | 2020-12-30 | — | — | EP | disclosed |
| WO-2010094426-A1 | METHOD FOR PRODUCING AN ANALYTICAL MAGAZINE | ROCHE DIAGNOSTICS GMBH (DE) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010094427-A2 | COMPACT STORAGE OF AUXILIARY ANALYTICAL DEVICES IN A CARTRIDGE | ROCHE DIAGNOSTICS GMBH | 2010-08-26 | — | — | WO | disclosed |
| US-20090246818-A1 | COMPOUNDS, METHODS, COMPLEXES, APPARATUSES AND USES RELATING TO STABILE FORMS OF NAD/NADH | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |
| WO-2009103540-A1 | STABILIZATION OF DEHYDROGENASES USING STABLE COENZYMES | F. HOFFMANN - LA ROCHE AG (CH) | 2009-08-27 | — | — | WO | disclosed |
| EP-2093284-A1 | Stabilisation of dehydrogenases with stable coenzymes | F.HOFFMANN-LA ROCHE AG (CH) | 2009-08-26 | — | — | EP | disclosed |
| US-7553615-B2 | Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080213809-A1 | Coenzyme substrates; kits; nicotinamide adenine dinucleotide; biochemical detection | ROCHE DIABETES CARE, INC. | 2008-09-04 | — | — | US | disclosed |
| EP-1907408-A1 | STABLE NAD/NADH DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| US-20070026476-A1 | COMPOUNDS, METHODS, COMPLEXES, APPARATUSES AND USES RELATING TO STABILE FORMS OF NAD/NADH | ROCHE DIABETES CARE, INC. | 2007-02-01 | — | — | US | disclosed |
| WO-2007012494-A1 | STABLE NAD/NADH DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070026476-A1 | COMPOUNDS, METHODS, COMPLEXES, APPARATUSES AND USES RELATING TO STABILE FORMS OF NAD/NADH | NQO1, NADK, NAMPT | LGALS8 4315/4885OGA 397/4885SLC2A1 1581/4885 |
| US-20080213809-A1 | Coenzyme substrates; kits; nicotinamide adenine dinucleotide; biochemical detection | NQO1, NADK, NAMPT | LGALS8 4320/4885OGA 950/4885SLC2A1 1356/4885 |
| US-20090246818-A1 | COMPOUNDS, METHODS, COMPLEXES, APPARATUSES AND USES RELATING TO STABILE FORMS OF NAD/NADH | NQO1, NADK, NAMPT | LGALS8 4315/4885OGA 397/4885SLC2A1 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.