SCHEMBL4606854

SCHEMBL4606854

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@@H]1O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 7/20 0.46
▸ OGA O60502 1/20 0.43
▸ SLC2A1 P11166 1/20 0.42
▸ MAPK1 P28482 1/20 0.41
▸ PYGB P11216 1/20 0.41
▸ LGALS1 P09382 2/20 0.38
▸ LGALS3 P17931 2/20 0.38
▸ LGALS9 O00182 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ SLC5A1 P13866 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6589158 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL9348641 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL440314 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL7927733 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL1820900 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL23026283 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL7919319 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL8614599 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL15353147 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB
SCHEMBL8586429 1.00 LGALS8 (0.46) LGALS8OGASLC2A1MAPK1PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1305284-B1 PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES UNIV MICHIGAN STATE (US) 2008-11-12 — — EP claimed
EP-1305284-A4 PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES UNIV MICHIGAN STATE (US) 2005-08-03 — — EP claimed
EP-1305284-A1 PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES MICHIGAN STATE UNIVERSITY (US) 2003-05-02 — — EP claimed
US-6423867-B1 FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2002-07-23 — — US claimed
US-20020026071-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY 2002-02-28 — — US claimed
US-20020026073-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2002-02-28 — — US claimed
US-20020026072-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2002-02-28 — — US claimed
US-20020026074-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS 2002-02-28 — — US claimed
US-20020019542-A1 Process and intermediate compounds for the preparation of pyrrolidines MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING 2002-02-14 — — US claimed
US-20020019561-A1 Process and intermediate compounds for the preparation of pyrrolidines BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2002-02-14 — — US claimed
WO-2002010130-A1 PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES MICHIGAN STATE UNIVERSITY (US) 2002-02-07 — — WO claimed
US-5659022-A Oligonucleotide-cyclopropapyrroloindole conjugates as sequence specific hybridization and crosslinking agents for nucleic acids EPOCH PHARMACEUTICALS, INC. (US) 1997-08-19 — — US claimed
EP-1305284-B1 PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES UNIV MICHIGAN STATE (US) 2008-11-12 — — EP disclosed
EP-1947084-A2 2-Pyrrolidones as intermediates for the preparation of pyrrolidines MICHIGAN STATE UNIVERSITY (US) 2008-07-23 — — EP disclosed
EP-1947082-A2 Oximes or imines of 4-pentulosonic acid methyl esters as intermediates for the preparation of pyrrolidines MICHIGAN STATE UNIVERSITY (US) 2008-07-23 — — EP disclosed
EP-1305284-A4 PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES UNIV MICHIGAN STATE (US) 2005-08-03 — — EP disclosed
US-5955597-A NUCLEOSIDES WHICH HYBRIDIZE TO RNA TARGET SEQUENCES, DIMERS, TRIMERS OR TETRAMERS GENTA, INCORPORATED (US) 1999-09-21 — — US disclosed
EP-0731809-A1 CHIRALLY ENRICHED SYNTHETIC PHOSPHONATE OLIGOMERS GENTA INCORPORATED (US) 1996-09-18 — — EP disclosed
US-5459243-A Apparatus and processes for the large scale generation and transfer of diazomethane ISIS PHARMACEUTICALS, INC. (US) 1995-10-17 — — US disclosed
WO-1995014031-A1 CHIRALLY ENRICHED SYNTHETIC PHOSPHONATE OLIGOMERS GENTA INCORPORATED (US) 1995-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020026073-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD LGALS8 2666/4885OGA 182/4885SLC2A1 1454/4885
US-20020026071-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD LGALS8 2666/4885OGA 182/4885SLC2A1 1454/4885
US-20020019542-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD LGALS8 2666/4885OGA 182/4885SLC2A1 1454/4885
US-20020026074-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD LGALS8 2666/4885OGA 182/4885SLC2A1 1454/4885
US-20020026072-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD LGALS8 2666/4885OGA 182/4885SLC2A1 1454/4885
US-20020019561-A1 Process and intermediate compounds for the preparation of pyrrolidines UMPS, DUT, DPYD LGALS8 2666/4885OGA 182/4885SLC2A1 1454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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