Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 8/20 | 0.54 |
| ▸ | ACHE | P22303 | 8/20 | 0.54 |
| ▸ | CHKA | P35790 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12533274 | 1.00 | HTT (0.82) | HTTMEN1TP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL30903821 | 0.97 | HTT (0.78) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL12533280 | 0.97 | HTT (0.77) | HTTMEN1TP53CYP1A2CYP2D6 | |
| Iodide SCHEMBL1932275 | 0.94 | HTT (0.74) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL18234751 | 0.92 | HTT (0.70) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL1816189 | 0.91 | HTT (1.00) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL2330291 | 0.91 | HTT (1.00) | HTTMEN1TP53CYP1A2CYP2D6 | |
| Miripirium SCHEMBL3477808 | 0.91 | HTT (1.00) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL5305098 | 0.91 | HTT (1.00) | HTTMEN1TP53CYP1A2CYP2D6 | |
| SCHEMBL2870371 | 0.91 | HTT (1.00) | HTTMEN1TP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024169380-A1 | MONOMER M1 AND DIMER D1, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 东南大学 | 2024-08-22 | — | — | WO | claimed |
| CN-116239584-B | Monomer M1, dimer D1 and preparation method and application thereof | 东南大学 | 2024-06-11 | — | — | CN | claimed |
| CN-116239584-A | Monomer M1, dimer D1 and preparation method and application thereof | 东南大学 | 2023-06-09 | — | — | CN | claimed |
| WO-2024169380-A1 | MONOMER M1 AND DIMER D1, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 东南大学 | 2024-08-22 | — | — | WO | disclosed |
| CN-116239584-B | Monomer M1, dimer D1 and preparation method and application thereof | 东南大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-116239584-A | Monomer M1, dimer D1 and preparation method and application thereof | 东南大学 | 2023-06-09 | — | — | CN | disclosed |
| US-8178678-B2 | Bis-quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069432-A1 | Bis-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | CHRNA2, CHRNA5, CHRNA4 | HTT 603/4885MEN1 4255/4885TP53 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.