SCHEMBL440420

SCHEMBL440420

CC(C)OC(=O)c1cc[c]c(OC(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.50
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA7 P43166 6/20 0.50
CA9 Q16790 6/20 0.50
CA14 Q9ULX7 6/20 0.50
SMN1; SMN2 Q16637 4/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
HTT P42858 3/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
JMJD6 Q6NYC1 1/20 0.39
ALDH1A1 P00352 5/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6950001 0.80 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL6134999 0.79 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL129051 0.73 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL676545 0.73 ALDH1A1 (0.40) HTTMEN1KMT2AALDH1A1KDM4E
SCHEMBL15474744 0.72 ICAM1 (0.36) CA12CA1CA2CA7CA9
SCHEMBL8772807 0.72 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL1817014 0.72 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL43683 0.71 NPC1 (0.65) CA12CA1CA2CA7CA9
SCHEMBL701832 0.70 CA12 (0.83) CA12CA1CA2CA7CA9
SCHEMBL16606258 0.70 CA12 (0.75) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703202-B2 Coated tablets JAGOTEC AG (CH) 2014-04-22 US disclosed
EP-1276465-B1 IMPROVED WATER-INSOLUBLE DRUG PARTICLE PROCESS JAGOTEC AG (CH) 2014-03-12 EP disclosed
US-8586094-B2 Coated tablets JAGOTEC AG (CH) 2013-11-19 US disclosed
US-20120064160-A1 Fibrate-statin Combinations with Reduced Fed-fasted Effects JAGOTEC AG (CH) 2012-03-15 US disclosed
EP-1320362-B1 STABILISED FIBRATE MICROPARTICLES JAGOTEC AG (CH) 2011-08-31 EP disclosed
EP-2228060-A1 Oral dosage forms comprising fenofibrate SKYEPHARMA CANADA INC. (CA) 2010-09-15 EP disclosed
EP-1796625-A4 NOVEL FENOFIBRATE FORMULATIONS AND RELATED METHODS OF TREATMENT TRANSFORM PHARMACEUTICALS INC (US) 2009-07-15 EP disclosed
US-20090149533-A1 NOVEL FENOFIBRATE FORMULATIONS AND RELATED METHODS OF TREATMENT TRANSFORM PHARMACEUTICALS, INC. (US) 2009-06-11 US disclosed
EP-1322289-B1 SPRAY DRYING PROCESS OF COMPOSITIONS CONTAINING FENOFIBRATE JAGOTEC AG (CH) 2007-07-25 EP disclosed
EP-1796625-A2 NOVEL FENOFIBRATE FORMULATIONS AND RELATED METHODS OF TREATMENT Transform Pharmaceuticals, Inc. (US) 2007-06-20 EP disclosed
US-6534088-B2 Dosage form of a statin and microparticles of fenofibrate stabilized by a phospholipid surface active substrance; bioavailability unaffected by food intake SKYEPHARMA CANADA INC. (CA) 2003-03-18 US disclosed
EP-1276465-A2 IMPROVED WATER-INSOLUBLE DRUG PARTICLE PROCESS RTP Pharma Inc. (US) 2003-01-22 EP disclosed
US-20020161032-A1 Fibrate-statin combinations with reduced fed-fasted effects SKYEPHARMA AG (CH) 2002-10-31 US disclosed
WO-2002067901-A1 FIBRATE-STATIN COMBINATIONS WITH REDUCED FED-FASTED EFFECTS SKYEPHARMA CANADA INC. (CA) 2002-09-06 WO disclosed
US-20020058065-A1 Insoluble drug particle compositions with improved fasted-fed effects JAGO RESEARCH AG (CH) 2002-05-16 US disclosed
US-20020056206-A1 Spray drying process and compositions of fenofibrate RTP PHARMA INC. (CA) 2002-05-16 US disclosed
WO-2002024169-A1 SPRAY DRYING PROCESS AND COMPOSITIONS OF FENOFIBRATE SKYEPHARMA CANADA INC. (CA) 2002-03-28 WO disclosed
WO-2002024193-A1 STABILISED FIBRATE MICROPARTICLES SKYEPHARMA CANADA INC. (CA) 2002-03-28 WO disclosed
US-20020012704-A1 Water-insoluble drug particle process JAGO RESEARCH AG (CH) 2002-01-31 US disclosed
WO-2001080828-A2 IMPROVED WATER-INSOLUBLE DRUG PARTICLE PROCESS RTP PHARMA INC. (US) 2001-11-01 WO disclosed