SCHEMBL43683

SCHEMBL43683

CC(C)OC(=O)c1cccc(C(=O)OC(C)C)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.65
RAB9A P51151 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
HTT P42858 2/20 0.65
MAPT P10636 2/20 0.65
CA12 O43570 6/20 0.63
CA1 P00915 6/20 0.63
CA2 P00918 6/20 0.63
CA7 P43166 6/20 0.63
CA9 Q16790 6/20 0.63
CA14 Q9ULX7 6/20 0.63
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
PDCD1 Q15116 1/20 0.58
CD274 Q9NZQ7 1/20 0.58
ALDH1A1 P00352 3/20 0.55
LMNA P02545 2/20 0.54
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
JMJD6 Q6NYC1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27683331 0.92 RAB9A (0.62) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL30678268 0.92 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL6233392 0.92 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL23471093 0.91 NPC1 (0.56) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL820795 0.89 NPC1 (0.55) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL161684 0.88 CA12 (0.67) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL6057062 0.88 RAB9A (0.58) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL161683 0.88 NPC1 (0.58) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL16077013 0.87 SMN1; SMN2 (0.56) NPC1RAB9ASMN1; SMN2HTTMAPT
SCHEMBL6569149 0.87 NPC1 (0.56) NPC1RAB9ASMN1; SMN2HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478563-B Method for rapidly crystallizing isosorbide 国科温州研究院(温州生物材料与工程研究所) 2023-09-29 CN claimed
CN-114478563-A Method for quickly crystallizing isosorbide 国科温州研究院(温州生物材料与工程研究所) 2022-05-13 CN claimed
US-20080171659-A1 Insecticidally Coated Fertilizer Solids ETIGRA 2008-07-17 US claimed
US-6703339-B2 COORIDNATION CATALYST CHINA PETRO-CHEMICAL CORPORATION (CN) 2004-03-09 US claimed
US-20020010081-A1 Components and catalysts for the (co) polymerization of olefins BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, SINOPEC, JOINTLY (CN) 2002-01-24 US claimed
EP-2658541-B2 TOPICAL LOCALIZED ISOXAZOLINE FORMULATION COMPRISING GLYCOFUROL INTERVET INT BV (NL) 2025-12-17 EP disclosed
EP-4613096-A2 ANTIPARASITIC COMPOUNDS Intervet International B.V. (NL) 2025-09-10 EP disclosed
US-12390450-B2 Antiparasitic pour-on compositions INTERVET INC. (US) 2025-08-19 US disclosed
EP-2658542-B2 TOPICAL LOCALIZED ISOXAZOLINE FORMULATION INTERVET INT BV (NL) 2025-06-04 EP disclosed
EP-4559482-A2 ANTIPARASITIC POUR-ON COMPOSITIONS Intervet International B.V. (NL) 2025-05-28 EP disclosed
EP-3727375-B1 ANTIPARASITIC POUR-ON COMPOSITIONS INTERVET INT BV (NL) 2025-03-19 EP disclosed
US-20240315993-A1 ANTIPARASITIC COMPOUNDS INTERVET INC. (US) 2024-09-26 US disclosed
EP-0039155-B1 POLYESTER MOLDING COMPOSITION, PRODUCTION THEREOF AND MOLDED ARTICLES PRODUCED THEREFROM Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-10-09 EP disclosed
US-4524191-A AN AROMATIC POLYAMIDE NUCLEATING AGENT TO ACCELERATE THE CRYSTALLIZATION OF POLYT YLENE TEREPHTLATE DURING INJECTION MOLDING ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-06-18 US disclosed
US-4440920-A ISOPHTHALIC OR TEREPHTHALIC ACID WITH BIS/HYDROXYPHENYL/ SULFONE AND 2,2-BIS/4-HYDROXYPHENYL/PROPANE MITSUI TOATSU CHEMICALS, INC. (JP) 1984-04-03 US disclosed
US-4417021-A POLYAMIDES, POLYHYDRAZIDES AS NUCLEATION AGENTS, MOLDING ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-11-22 US disclosed
EP-0077834-A1 AROMATIC POLYESTER MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-05-04 EP disclosed
EP-0039155-A1 Polyester molding composition, production thereof and molded articles produced therefrom Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1981-11-04 EP disclosed
US-4107150-A High impact terephthalate copolyesters using 1,4-butanediol and 1,4-cyclohexanedimethanol PHILLIPS PETROLEUM COMPANY (US) 1978-08-15 US disclosed
US-4049635-A TRANSESTERIFICATION PHILLIPS PETROLEUM COMPANY (US) 1977-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390450-B2 Antiparasitic pour-on compositions PIGS, ARG1, ARG2 NPC1 1722/4885RAB9A 3227/4885SMN1; SMN2 2465/4885
US-20240315993-A1 ANTIPARASITIC COMPOUNDS PIGO, CAT, CYP51A1 NPC1 733/4885RAB9A 1543/4885SMN1; SMN2 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.