Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672982 | 0.90 | MET (0.69) | MET | |
| SCHEMBL2673339 | 0.89 | MET (0.75) | MET | |
| SCHEMBL2672869 | 0.89 | MET (0.91) | MET | |
| SCHEMBL4404447 | 0.88 | MET (0.79) | MET | |
| SCHEMBL2672833 | 0.88 | MET (0.79) | MET | |
| SCHEMBL2672939 | 0.87 | MET (0.88) | MET | |
| SCHEMBL12463380 | 0.87 | MET (0.70) | MET | |
| SCHEMBL13247309 | 0.86 | MET (0.69) | MET | |
| SCHEMBL2673288 | 0.84 | MET (0.83) | MET | |
| SCHEMBL2673105 | 0.84 | MET (1.00) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173653-B2 | Pyridiazinone derivatives for the treatment of tumours | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-08 | — | — | US | disclosed |