Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402540 | 0.91 | MET (0.66) | MET | |
| SCHEMBL4125302 | 0.91 | MET (0.90) | MET | |
| SCHEMBL4123635 | 0.91 | MET (0.79) | MET | |
| SCHEMBL2673485 | 0.89 | MET (0.77) | MET | |
| SCHEMBL2673288 | 0.88 | MET (0.83) | MET | |
| SCHEMBL2673152 | 0.88 | MET (0.83) | MET | |
| SCHEMBL2673105 | 0.88 | MET (1.00) | MET | |
| SCHEMBL2672939 | 0.88 | MET (0.88) | MET | |
| SCHEMBL4404311 | 0.88 | MET (0.72) | MET | |
| SCHEMBL2673290 | 0.88 | MET (0.87) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173653-B2 | Pyridiazinone derivatives for the treatment of tumours | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-08 | — | — | US | disclosed |