⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8248757 | 0.78 | GPR3 (0.40) | — | |
| SCHEMBL4406314 | 0.76 | — | — | |
| SCHEMBL4404597 | 0.75 | MAPT (0.41) | — | |
| SCHEMBL4412489 | 0.75 | — | — | |
| SCHEMBL4413940 | 0.71 | ADORA2A (0.37) | — | |
| SCHEMBL4404584 | 0.71 | HSD17B10 (0.45) | — | |
| SCHEMBL8703598 | 0.66 | NQO2 (0.35) | — | |
| SCHEMBL4408162 | 0.64 | GBA1 (0.37) | — | |
| SCHEMBL9863892 | 0.63 | ACHE (0.30) | — | |
| SCHEMBL5510470 | 0.60 | PDE10A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325889-A1 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | CAMPBELL DAVID ALAN | 2009-12-31 | — | — | US | claimed |
| US-20090325889-A1 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | CAMPBELL DAVID ALAN | 2009-12-31 | — | — | US | disclosed |
| EP-1915382-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | Phenomix Corporation (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007016476-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |