Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536216 | 0.93 | — | — | |
| SCHEMBL15567757 | 0.91 | TDP1 (0.47) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL31443227 | 0.85 | TDP1 (0.43) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL3459899 | 0.83 | TDP1 (0.44) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| Lactic Acid SCHEMBL27586439 | 0.81 | TP53 (0.46) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL6476278 | 0.79 | TDP1 (0.48) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL8461367 | 0.79 | TDP1 (0.39) | TDP1TSHRCYP3A4MAPTALDH1A1 | |
| SCHEMBL6368830 | 0.78 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL35945 | 0.77 | — | — | |
| SCHEMBL366726 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883690-B1 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | BATTELLE MEMORIAL INSTITUTE (US) | 2012-01-25 | — | — | EP | disclosed |
| US-20110269982-A1 | USE OF FATTY ACIDS AS FEED MATERIAL IN POLYOL PROCESS | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269979-A1 | Preparation of Esters and Polyols by Initial Oxidative Cleavage of Fatty Acids Followed by Esterification Reactions | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269978-A1 | Solvent-less Preparation of Polyols by Ozonolysis | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269981-A1 | Pre-Esterification Of Primary Polyols To Improve Solubility In Solvents Used In The Polyol Process | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| EP-2382177-A1 | Preparation of esters and polyols by initial oxidative cleavage of fatty acids followed by esterification reactions | Battelle Memorial Institute (US) | 2011-11-02 | — | — | EP | disclosed |
| EP-2382294-A1 | USE OF FATTY ACIDS AS FEED MATERIAL IN POLYOL PROCESS | Battelle Memorial Institute (US) | 2011-11-02 | — | — | EP | disclosed |
| EP-2382292-A1 | PRE-ESTERIFICATION OF PRIMARY POLYOLS TO IMPROVE SOLUBILITY IN SOLVENTS USED IN POLYOL PROCESS | Battelle Memorial Institute (US) | 2011-11-02 | — | — | EP | disclosed |
| EP-2382293-A1 | SOLVENT-LESS PREPARATION OF POLYOLS BY OZONOLYSIS | Battelle Memorial Institute (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20110237812-A1 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | BATTELLE MEMORIAL INSTITUTE (US) | 2011-09-29 | — | — | US | disclosed |
| US-7994354-B2 | Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2011-08-09 | — | — | US | disclosed |
| EP-2308955-A1 | Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2011-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269979-A1 | Preparation of Esters and Polyols by Initial Oxidative Cleavage of Fatty Acids Followed by Esterification Reactions | FASN, ELOVL1, ACSL1 | TDP1 2222/4885TSHR 4586/4885CYP3A4 337/4885 |
| US-20110269978-A1 | Solvent-less Preparation of Polyols by Ozonolysis | MGLL, PUF60, DAGLA | TDP1 642/4885TSHR 4522/4885CYP3A4 1367/4885 |
| US-20110269982-A1 | USE OF FATTY ACIDS AS FEED MATERIAL IN POLYOL PROCESS | FASN, ACSL1, ELOVL1 | TDP1 3957/4885TSHR 3468/4885CYP3A4 2377/4885 |
| US-20110237812-A1 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | FASN, MGLL, PUF60 | TDP1 1641/4885TSHR 4494/4885CYP3A4 1333/4885 |
| US-20110269981-A1 | Pre-Esterification Of Primary Polyols To Improve Solubility In Solvents Used In The Polyol Process | MGLL, FASN, ELOVL1 | TDP1 2252/4885TSHR 4652/4885CYP3A4 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.