SCHEMBL440469

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL441511	0.90	EPHX2 (0.53)	EPHX2KCNH2DGAT1CACNA1CTUBB4A
	SCHEMBL442980	0.85	TSHR (0.51)	DGAT1
	SCHEMBL442251	0.84	MEN1 (0.51)	EPHX2KCNH2DGAT1CACNA1CTUBB4A
	SCHEMBL438045	0.83	EPHX1 (0.54)	EPHX2KCNH2DGAT1TUBB4ATUBB
	SCHEMBL442386	0.82	DGAT1 (0.56)	DGAT1
	SCHEMBL443339	0.82	DGAT1 (0.49)	EPHX2KCNH2DGAT1CACNA1C
	SCHEMBL443338	0.82	DGAT1 (0.49)	EPHX2KCNH2DGAT1CACNA1C
	SCHEMBL440819	0.80	DGAT1 (0.56)	DGAT1
	SCHEMBL438158	0.80	DGAT1 (0.53)	DGAT1
	SCHEMBL438954	0.79	DGAT1 (0.49)	DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.