SCHEMBL4404793

SCHEMBL4404793

CO[C@H]1OC(CO[C@H]2OC(CO)[C@@H](O)[C@H](O)C2O)[C@@H](O)[C@H](O)C1O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.58
▸ CDK1 P06493 1/20 0.55
▸ CCNB1 P14635 1/20 0.55
▸ ACHE P22303 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ CA2 P00918 2/20 0.47
▸ LGALS8 O00214 2/20 0.47
▸ MAPT P10636 1/20 0.46
▸ CD209 Q9NNX6 1/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4527554 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL18650671 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL17254874 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL20050054 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL4275422 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL18654187 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL25142231 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL18650646 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL4275427 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1
SCHEMBL18650637 1.00 GAA (0.58) GAACDK1CCNB1ACHEL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9486441-B2 Compounds, compositions and methods for making the same SIGNUM BIOSCIENCES, INC. (US) 2016-11-08 — — US disclosed
US-8173606-B2 Sulfated oligosaccharide derivatives PROGEN PHARMACEUTICALS LIMITED (AU) 2012-05-08 — — US disclosed
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LIMITED (AU) 2011-06-02 — — US disclosed
US-7875592-B2 inhibitors of heparan sulfate-binding proteins and inhibitors of the enzyme heparanase; antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment, lowering of blood triglyceride levels and inhibition of cardiovascular disease PROGEN PHARMACEUTICALS LIMITED (AU) 2011-01-25 — — US disclosed
US-20070185037-A1 Sulfated oligosaccharide derivatives PROGEN INDUSTRIES LIMITED (AU) 2007-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185037-A1 Sulfated oligosaccharide derivatives HPSE, APOB, LIPG GAA 216/4885CDK1 3761/4885CCNB1 3703/4885
US-20110130354-A1 SULFATED OLIGOSACCHARIDE DERIVATIVES HPSE, APOB, LIPG GAA 216/4885CDK1 3761/4885CCNB1 3703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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