Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405062 | 1.00 | SLC7A5 (0.55) | SLC7A5OPRD1OPRM1OPRK1ERAP2 | |
| SCHEMBL4407092 | 0.94 | SLC7A5 (0.62) | SLC7A5OPRD1OPRM1OPRK1ERAP2 | |
| SCHEMBL4409294 | 0.94 | SLC7A5 (0.62) | SLC7A5OPRD1OPRM1OPRK1ERAP2 | |
| SCHEMBL6047681 | 0.94 | SLC7A5 (0.62) | SLC7A5OPRD1OPRM1OPRK1ERAP2 | |
| SCHEMBL30053224 | 0.88 | MME (0.56) | SLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL1330246 | 0.88 | MME (0.56) | SLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL1330243 | 0.88 | MME (0.56) | SLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL30760629 | 0.88 | MME (0.56) | SLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL30865865 | 0.88 | OPRD1 (0.70) | OPRD1OPRM1OPRK1 | |
| SCHEMBL17430646 | 0.88 | OPRD1 (0.70) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3518 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001910-A1 | PEPTIDES AND USES THEREOF | PREVECEUTICAL MEDICAL INC (CA) | 2026-01-01 | — | — | US | claimed |
| US-12459989-B2 | Antibody therapies for human immunodeficiency virus (HIV) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2025-11-04 | — | — | US | claimed |
| US-12297293-B2 | Peptide compounds targeting PD-1 receptor as well as preparation and applications thereof | NANTONG UNIVERSITY (CN) | 2025-05-13 | — | — | US | claimed |
| CN-118878633-A | Application of multi-target peptide in preparing analgesic drug | 南通大学 | 2024-11-01 | — | — | CN | claimed |
| US-20240336652-A1 | Peptide compounds targeting PD-1 receptor as well as preparation and applications thereof | UNIV NANTONG (CN) | 2024-10-10 | — | — | US | claimed |
| EP-4433495-A1 | PEPTIDES AND USES THEREOF | Preveceutical Medical Inc. (CA) | 2024-09-25 | — | — | EP | claimed |
| WO-2023089542-A1 | PEPTIDES AND USES THEREOF | PreveCeutical Medical Inc. (CA) | 2023-05-25 | — | — | WO | claimed |
| WO-2022257831-A1 | POLYPEPTIDE COMPOUNDS USING PD-1 RECEPTORS AS TARGETS, PREPARATION METHOD THEREFOR AND USE THEREOF | 南通大学 | 2022-12-15 | — | — | WO | claimed |
| EP-4011914-A1 | ANTIBODIES DIRECTED AGAINST LYMPHOCYTE ACTIVATION GENE 3 (LAG-3) | AnaptysBio, Inc. (US) | 2022-06-15 | — | — | EP | claimed |
| CN-113416232-B | Polypeptide compounds with PD-1 receptor as target spot, preparation method and application thereof | 南通大学 | 2022-06-03 | — | — | CN | claimed |
| US-11344610-B2 | Prevention and reduction of blood loss | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-05-31 | — | — | US | claimed |
| US-20220025021-A1 | ANTIBODY THERAPIES FOR HUMAN IMMUNODEFICIENCY VIRUS (HIV) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2022-01-27 | — | — | US | claimed |
| EP-0635026-B1 | NOVEL LIPOPHILIC OLIGOPEPTIDES WITH IMMUNOMODULATING ACTIVITY | IAF BIOCHEM INT (CA) | 1999-11-10 | — | — | EP | claimed |
| EP-0597838-B1 | VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE INC (CA) | 1998-12-02 | — | — | EP | claimed |
| EP-0549617-B1 | IMPROVED VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE INC (CA) | 1996-03-27 | — | — | EP | claimed |
| EP-0597838-A1 | VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE, INC. (CA) | 1994-05-25 | — | — | EP | claimed |
| EP-0549617-A1 | IMPROVED VACCINE COMPOSITIONS. | NORTH AMERICAN VACCINE INC (CA) | 1993-07-07 | — | — | EP | claimed |
| WO-1992004915-A1 | IMPROVED VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE, INC. (CA) | 1992-04-02 | — | — | WO | claimed |
| WO-1991016926-A1 | VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE, INC. (CA) | 1991-11-14 | — | — | WO | claimed |
| CN-107513103-B | MASP isoforms as inhibitors of complement activation | OMEROS CORP. (US) | 2026-05-26 | — | — | CN | disclosed |
| CN-114761428-B | Anti-hemagglutinin antibodies and methods of use thereof | 瑞泽恩制药公司 | 2026-05-22 | — | — | CN | disclosed |
| CN-115433277-B | Preparation and application of anti-CD 38 rabbit recombinant monoclonal antibody | 苏州缔码生物科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-115335392-B | Inhibition of shade-avoidance response in plants | 成对植物服务股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-12617971-B2 | Anti-viral coating composition, and method for fixing anti-viral fusion protein to surfaces | AMOLIFESCIENCE CO., LTD. (KR) | 2026-05-05 | — | — | US | disclosed |
| WO-2026089754-A1 | COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES | Finitus, LLC (US) | 2026-04-30 | — | — | WO | disclosed |
| WO-2026089752-A1 | COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES | Finitus, LLC (US) | 2026-04-30 | — | — | WO | disclosed |
| US-20260108467-A1 | COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES | FINITUS LLC (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260108583-A1 | COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES | FINITUS LLC (US) | 2026-04-23 | — | — | US | disclosed |
| EP-4354146-B1 | IMMUNOASSAY FOR THE DETECTION OF CLEAVED HIGH MOLECULAR WEIGHT KININOGEN | TAKEDA PHARMACEUTICALS CO (JP) | 2026-04-15 | — | — | EP | disclosed |
| EP-4715064-A2 | RNA BIOMARKERS FOR HEREDITARY ANGIOEDEMA | Takeda Pharmaceutical Company Limited (JP) | 2026-03-25 | — | — | EP | disclosed |
| US-12583911-B2 | Human immunodeficiency virus GP120 binding proteins | VIIV Healthcare UK (No.5) Limited (GB) | 2026-03-24 | — | — | US | disclosed |
| CN-116023447-B | BmoR mutant-based wide-area biosensor | 北京理工大学 | 2026-02-27 | — | — | CN | disclosed |
| EP-3513196-B1 | PROTEIN BIOMARKERS FOR DISEASES ASSOCIATED WITH THE CONTACT ACTIVATION SYSTEM | TAKEDA PHARMACEUTICALS CO (JP) | 2026-02-25 | — | — | EP | disclosed |
| US-12534703-B2 | Cell culture substrate and manufacturing method therefor | AMOLIFESCIENCE CO., LTD. (KR) | 2026-01-27 | — | — | US | disclosed |
| US-20260001910-A1 | PEPTIDES AND USES THEREOF | PREVECEUTICAL MEDICAL INC (CA) | 2026-01-01 | — | — | US | disclosed |
| EP-3526236-B1 | SIGNATURE-BASED HUMAN IMMUNODEFICIENCY VIRUS (HIV) ENVELOPE (ENV) TRIMER VACCINES AND METHODS OF USING THE SAME | BETH ISRAEL DEACONESS MEDICAL CT INC (US) | 2025-12-10 | — | — | EP | disclosed |
| US-12493047-B2 | Cleaved high molecule weight kininogen (HMWK) antibodies and methods of using | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-12-09 | — | — | US | disclosed |
| EP-3513188-B1 | RNA BIOMARKERS FOR HEREDITARY ANGIOEDEMA | TAKEDA PHARMACEUTICALS CO (JP) | 2025-12-03 | — | — | EP | disclosed |
| US-12467025-B2 | Cell culture sheet and large-capacity cell culture device including same | AMOLIFESCIENCE CO., LTD. (KR) | 2025-11-11 | — | — | US | disclosed |
| WO-2025229018-A1 | NEUTRALIZING ANTIBODY CONSTRUCTS AGAINST HIV | VIIV Healthcare UK (No.5) Limited (GB) | 2025-11-06 | — | — | WO | disclosed |
| US-12459989-B2 | Antibody therapies for human immunodeficiency virus (HIV) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-20250333454-A1 | RECOMBINANT ADENOVIRUSES AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CT INC (US) | 2025-10-30 | — | — | US | disclosed |
| US-12442824-B2 | Assays for determining plasma kallikrein system biomarkers | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-10-14 | — | — | US | disclosed |
| US-12421485-B2 | Cell culture sheet assembly for large-capacity incubator, and large-capacity incubator comprising same | AMOGREENTECH CO., LTD. (KR) | 2025-09-23 | — | — | US | disclosed |
| EP-4611813-A1 | ANTIGEN BINDING PROTEINS | VIIV Healthcare UK (No.5) Limited (GB) | 2025-09-10 | — | — | EP | disclosed |
| US-20250250328-A1 | Antigen Binding Proteins | VIIV Healthcare UK (No.5) Limited (GB) | 2025-08-07 | — | — | US | disclosed |
| EP-4597115-A2 | PEPTIDE QUANTITATION ASSAY FOR DIFFERENTIATING FULL-LENGTH HIGH MOLECULAR WEIGHT KININOGEN (HMWK) AND CLEAVED HMWK | Takeda Pharmaceutical Company Limited (JP) | 2025-08-06 | — | — | EP | disclosed |
| US-20250230218-A1 | PDL1 PEPTIDES FOR USE IN CANCER VACCINES | IO BIOTECH APS (DK) | 2025-07-17 | — | — | US | disclosed |
| US-20250208143-A1 | p53 FRAGMENTS AS MARKERS FOR DIAGNOSIS AND PROGNOSIS OF NEURODEGENERATIVE DISEASE STATES | DIADEM SPA (IT) | 2025-06-26 | — | — | US | disclosed |
| EP-4574040-A2 | EVACUATED BLOOD COLLECTION TUBES CONTAINING PROTEASE INHIBITORS FOR THE ASSESSMENT OF CONTACT SYSTEM ACTIVATION | Takeda Pharmaceutical Company Limited (JP) | 2025-06-25 | — | — | EP | disclosed |
| CN-112236196-B | Atrial natriuretic peptide grafted antibodies | 拜耳公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-116234910-B | Antibodies that bind human IL-33, methods of making and uses thereof | 三生国健药业（上海）股份有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-114258399-B | Protein container, polynucleotide, vector, expression cassette, cell, method for producing container, method for identifying pathogen or diagnosing disease, use of container, and diagnostic kit | 奥斯瓦道·克鲁兹基金会 | 2025-06-24 | — | — | CN | disclosed |
| CN-114057869-B | Human antibodies against the middle east respiratory syndrome coronavirus spike protein | 瑞泽恩制药公司 | 2025-06-24 | — | — | CN | disclosed |
| US-20250199014-A1 | METABOLITE BIOMARKERS FOR DISEASES ASSOCIATED WITH THE CONTACT ACTIVATION SYSTEM | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-06-19 | — | — | US | disclosed |
| CN-111787951-B | IgM Fc and J chain mutations affecting IgM serum half-life | IGM生物科学股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-112261874-B | Inhibition of fungal growth by manganese depletion | 科·汉森有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-113444183-B | Fusion partners for peptide production | 佩利肯科技控股公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-113271972-B | Multimeric hybrid Fc proteins for IVIG substitution | JN生物科学有限责任公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-114835784-B | Anti-inflammatory peptides and uses thereof | 巴斯夫美容护理法国公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-107913398-B | Application of polypeptide in preventing or treating thrombotic diseases | 广东医科大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-114163531-B | Tissue factor pathway inhibitor antibodies and uses thereof | 辉瑞公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-114621937-B | Mutant of serine hydroxymethyl transferase and application thereof | 武汉远大弘元股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-114796452-B | Inflammatory skin disease biomarker DDX5 and/or sIL-36R and application thereof | 华东师范大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-114555817-B | Rhamnose polysaccharide | 敦提大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-113908268-B | Use of antibodies in the preparation of a medicament for the treatment or prevention of migraine | 美国安进公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-114207139-B | Method for uncoupling yield and productivity of non-catabolic compounds produced by host cells | 阿迈瑞斯公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-109721650-B | Application of silk gland incremental expression antibacterial peptide BmGlv2 in improvement of silk antibacterial performance and method | 西南大学 | 2025-06-10 | — | — | CN | disclosed |
| US-20250179199-A1 | ANTIBODIES TO CANINE INTERLEUKIN-4 RECEPTOR ALPHA | INTERVET INC. (US) | 2025-06-05 | — | — | US | disclosed |
| CN-114729024-B | Peptide antigens and uses thereof | 博爱米拉索勒股份公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-113710807-B | Microorganisms and methods for producing oxygenates from hexoses | 布拉斯科公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-114126646-B | Sequence-based high-throughput methods to generate camelid antibodies covering a broad range of epitopes with high resolution | 浙江纳米抗体技术中心有限公司 | 2025-05-30 | — | — | CN | disclosed |
| US-20250172567-A1 | PEPTIDE QUANTITATION ASSAY FOR DIFFERENTIATING FULL-LENGTH HIGH MOLECULAR WEIGHT KININOGEN (HMWK) AND CLEAVED HMWK | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-05-29 | — | — | US | disclosed |
| US-20250172555-A1 | DEVICE FOR DETECTION AND PROGNOSTIC ASSESSMENT OF NEURODEGENERATIVE DISORDERS | DIADEM SPA (IT) | 2025-05-29 | — | — | US | disclosed |
| CN-113038964-B | Ultra-long acting insulin-FC fusion proteins and methods of use | 德克拉有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-113993898-B | RET-binding human antibodies and methods of use thereof | 瑞泽恩制药公司 | 2025-05-27 | — | — | CN | disclosed |
| US-12312382-B2 | Recombinant adenoviruses and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| CN-109055386-B | Silkworm BmSCP gene and recombinant expression vector and application thereof | 西南大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-114008197-B | Metabolic engineering for simultaneous consumption of xylose and glucose to produce chemicals from second generation sugars | 布拉斯科公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-113950534-B | Method for producing L-type cyclic amino acid | 株式会社API | 2025-05-20 | — | — | CN | disclosed |
| US-12305193-B2 | Three-dimensional micro-environment structure for controlling cell behavior, three-dimensional surface for controlling cell behavior, and method for manufacturing array and three-dimensional micro-environment structure | AMOLIFESCIENCE CO., LTD. (KR) | 2025-05-20 | — | — | US | disclosed |
| CN-114507282-B | Human monoclonal anti-PD-L1 antibodies and methods of use | 达纳－法伯癌症研究所公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-113968912-B | Chimeric antigen receptor targeting G-protein coupled receptor and use thereof | 纪念斯隆-凯特琳癌症中心 | 2025-05-16 | — | — | CN | disclosed |
| CN-109789225-B | DNA monoclonal antibodies targeting checkpoint molecules | 宾夕法尼亚大学理事会 | 2025-05-13 | — | — | CN | disclosed |
| CN-113302207-B | Antibodies to CD38 and ICAM1 and uses thereof | 维尔托索宾科公司 | 2025-05-13 | — | — | CN | disclosed |
| US-12297293-B2 | Peptide compounds targeting PD-1 receptor as well as preparation and applications thereof | NANTONG UNIVERSITY (CN) | 2025-05-13 | — | — | US | disclosed |
| CN-115362259-B | Process for producing copolymerized polyhydroxyalkanoate mixture, and transformed microorganism | 株式会社钟化 | 2025-05-13 | — | — | CN | disclosed |
| CN-115558667-B | Gene for regulating zinc transport of north China camel hair and chenopodium quinoa and application thereof | 蒙草生态环境(集团)股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-112789684-B | Methods and systems for predicting response to PD-1 axis guided therapy | 文塔纳医疗系统公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-115232836-B | Gene editing system for constructing CRYGC gene mutation congenital cataract model pig nuclear transplantation donor cell and application thereof | 南京启真基因工程有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-113227122-B | Alphavirus-based replicons for administration of biotherapeutic agents | 杨森制药公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-112261949-B | Variant asparaginase polypeptides for medical use | 伊兰科美国公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-112538114-B | Anti-human CD38 antibodies and uses thereof | 上海普铭生物科技有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-111886336-B | CASZ compositions and methods of use | 加利福尼亚大学董事会 | 2025-05-02 | — | — | CN | disclosed |
| CN-113584015-B | Formation of synthons | 新英格兰生物实验室公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-113767115-B | Therapeutic interferon alpha 1 proteins | 奥里尼斯生物科学股份有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-112601808-B | Microorganism producing eicosapentaenoic acid and process for producing eicosapentaenoic acid | 协和发酵生化株式会社 | 2025-05-02 | — | — | CN | disclosed |
| CN-113271956-B | Matrix metalloproteinase cleavable and serine or cysteine proteinase cleavable substrates and methods of use thereof | 西托姆克斯治疗公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-114126665-B | Gene therapy for yellow spot disease of ocular fundus (ABCA 4) | 马萨诸塞大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-114126645-B | Modified S1 subunit of coronavirus spike protein | 勃林格殷格翰动物保健有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114174321-B | Modified S2 subunit of coronavirus spike protein | 勃林格殷格翰动物保健有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-112996536-B | H52 IBV vaccine with heterologous spike protein | 勃林格殷格翰动物保健有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-12281144-B2 | Methods and compositions for regenerating tissues | NellOne Therapeutics, Inc. (US) | 2025-04-22 | — | — | US | disclosed |
| CN-110945120-B | Determination of potency of receptor-ligand interactions in nanomedicines | 优迪有限合伙公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-115335526-B | Ribozyme-mediated RNA assembly and expression | 罗切斯特大学 | 2025-04-18 | — | — | CN | disclosed |
| CN-114096563-B | Antibodies that specifically bind to B7-H3 and uses thereof | Y生物股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-115851688-B | TrpCF mutant and application thereof | 胡丹 | 2025-04-18 | — | — | CN | disclosed |
| CN-113287013-B | Method for examining ulcerative colitis and primary sclerosing cholangitis | 国立大学法人京都大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116970289-B | Enzyme reaction water-soluble fluorescent dye based on oxygen control, preparation method and application | 中国科学院过程工程研究所 | 2025-04-15 | — | — | CN | disclosed |
| CN-112601811-B | Production of engineered cells and uses thereof | 泰莱托恩基金会第三部门组织 | 2025-04-15 | — | — | CN | disclosed |
| CN-114585637-B | MASP-inhibitory compounds and uses thereof | 拜耳公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114478780-B | Antibody recognizing multiple different epitopes of glypican 3 and application thereof | 华中农业大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-113195532-B | Compositions and methods for increasing body weight and lean muscle mass using antagonists directed to leptin receptor, GDF8 and activin A | 瑞泽恩制药公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-114729303-B | Electron mediator, method for producing electron mediator, and method for transferring electrons | 松下知识产权经营株式会社 | 2025-04-11 | — | — | CN | disclosed |
| CN-112740044-B | Method for diagnosis or prognosis of neurological disorders | 阿尔斯特创新有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-114634575-B | Development and application of complement inhibitor | 康诺亚生物医药科技（成都）有限公司 | 2025-04-11 | — | — | CN | disclosed |
| EP-3909509-B1 | EVACUATED BLOOD COLLECTION TUBES CONTAINING PROTEASE INHIBITORS FOR THE ASSESSMENT OF CONTACT SYSTEM ACTIVATION | TAKEDA PHARMACEUTICALS CO (JP) | 2025-04-09 | — | — | EP | disclosed |
| CN-114867739-B | Fusion polypeptides comprising GDF15 and a polypeptide domain capable of O-glycosylation | 株式会社LG化学 | 2025-04-08 | — | — | CN | disclosed |
| CN-109890412-B | Modified factor H binding proteins | 牛津大学创新有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-110945019-B | Combination of MHC class Ib molecules and peptides for targeted therapeutic immunomodulation | 尤利乌斯·马克西米利安维尔茨堡大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-115873820-B | Nicotinamide mononucleotide adenosine transferase mutant | 尚科生物医药（上海）有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-115851811-B | Application of receptor kinase PXY in controlling plant bud regeneration | 陕西师范大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-115916247-B | Human TIGIT specific single domain antibodies and uses thereof | 奥美药业有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-114075288-B | Anti-PD-L2 antibodies | 正大天晴药业集团股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-115247191-B | Gene editing system and application thereof in construction of double-gene mutated nevus basal cell carcinoma syndrome pig nuclear transfer donor cells | 南京启真基因工程有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-113891897-B | Composition and method for producing the same | 新加坡科技研究局 | 2025-03-25 | — | — | CN | disclosed |
| CN-112752872-B | Method for preparing protein fiber | 丝芭博株式会社 | 2025-03-25 | — | — | CN | disclosed |
| CN-113993903-B | Tetravalent bispecific antibody for resisting PD-1 and PD-L1 | 三生国健药业（上海）股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-114958797-B | Mutant DNA polymerase, coding gene, recombinant expression vector, recombinant bacterium and application thereof | 郑州思昆生物工程有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-111201237-B | HLAII-type restricted T cell receptor for mutated RAS | 美国卫生和人力服务部 | 2025-03-25 | — | — | CN | disclosed |
| CN-115068664-B | Bioadhesive composition comprising mussel adhesive proteins and method of making same | 浦项工科大学校产学协力团 | 2025-03-21 | — | — | CN | disclosed |
| CN-119661673-A | Cold-resistance negative regulation gene OsbHLH090 of rice and application thereof | 南京农业大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-114096666-B | Compositions and methods for treating heme lesions | 比姆医疗股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-114144519-B | Single base substitution proteins and compositions comprising the same | 株式会社图尔金 | 2025-03-18 | — | — | CN | disclosed |
| CN-112262215-B | Chimeric vectors | 美国卫生和人力服务部 | 2025-03-18 | — | — | CN | disclosed |
| CN-114652816-B | Compositions containing HC-HA/PTX3 complexes and methods of use thereof | 生物组织控股公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-114099424-B | Preparation of recombinant immunocytokine | 越海百奥药业(绍兴)有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-114751989-B | Antigen binding molecules comprising trimeric TNF family ligands | 豪夫迈·罗氏有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-112272560-B | Biologically relevant orthogonal cytokine/receptor pairs | 小利兰·斯坦福大学托管委员会 | 2025-03-14 | — | — | CN | disclosed |
| CN-114264814-B | Antibody detection kit of PD-1 biological agent and preparation method thereof | 苏州和锐生物科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-116003542-B | Microorganism for producing citric acid, construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2025-03-14 | — | — | CN | disclosed |
| US-20250082824-A1 | METHOD FOR MANUFACTURING YARN FOR A CELL CULTURE SCAFFOLD | AMOLIFESCIENCE CO LTD (KR) | 2025-03-13 | — | — | US | disclosed |
| US-20250084368-A1 | CELL CULTURE SCAFFOLD, AND PREPARATION METHOD THEREOF | AMOLIFESCIENCE CO., LTD. (KR) | 2025-03-13 | — | — | US | disclosed |
| EP-3390439-B1 | PEPTIDE QUANTITATION ASSAY FOR DIFFERENTIATING FULL-LENGTH HIGH MOLECULAR WEIGHT KININOGEN (HMWK) AND CLEAVED HMWK | TAKEDA PHARMACEUTICALS CO (JP) | 2025-03-12 | — | — | EP | disclosed |
| CN-111819197-B | Anti-NGF antibodies and methods thereof | 硕腾服务有限责任公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-112912404-B | Fusion proteins comprising IDS and uses thereof | 财团法人牧岩生命科学研究所 | 2025-03-11 | — | — | CN | disclosed |
| CN-114901679-B | Novel masked cytokines and uses thereof | 奥美药业有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-112292140-B | Chimeric antigen receptor targeting CD37 and CD19 | 综合医院公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-113784758-B | Non-plant host cells producing tropane alkaloids (TA) and methods of making and using the same | 小利兰·斯坦福大学托管委员会 | 2025-03-07 | — | — | CN | disclosed |
| CN-113164538-B | Modified oncolytic viruses, compositions and uses thereof | 上海锦斯生物技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-113412117-B | Chimeric antigens and T cell receptors and methods of use | 凯德药业股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-109069615-B | Compositions and methods for vaccinating against dengue virus in children and young people | 武田疫苗股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-113631574-B | Multispecific antibodies specific for TNFalpha and IL-17A, antibodies targeting IL-17A, and methods of use thereof | 努玛治疗有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-114599787-B | Sustainable production of cannabinoids from simple precursor feedstocks using Saccharomyces cerevisiae (Saccharomyces Cerevisiae) | 新加坡国立大学 | 2025-02-28 | — | — | CN | disclosed |
| CN-114127120-B | Anti-carbonic anhydrase IX antibodies | 纳维再生科技股份有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-114380922-B | Fusion proteins producing point mutations in cells, their preparation and use | 中国科学院上海营养与健康研究所 | 2025-02-28 | — | — | CN | disclosed |
| CN-115087464-B | Novel interleukin-15 (IL-15) fusion proteins and uses thereof | 科优基因公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114195894-B | Antibody targeting 4-1BB and application thereof | 普米斯生物技术(珠海)有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-112041342-B | Combination antagonists against IL-5/IL-5R and IL-4/IL-4R or IL-13/IL-13R | 阿根思公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-113557240-B | Norovirus-like particles with improved stability | 爱康遗传有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114945571-B | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114062670-B | Method, antibody set and kit for measuring virus antigen in sample | 希森美康株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-113474359-B | Novel fusion proteins specific for CD137 and GPC3 | 皮里斯制药有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-114096275-B | Novel BSSL antibodies | 利普姆股份制有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-119464313-A | Sorghum anthracnose susceptibility gene SbABCA, recombinant plasmid and application thereof | 贵州大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-114450023-B | Vaccine composition for severe fever with thrombocytopenia syndrome virus | 首尔大学校产业协力团 | 2025-02-18 | — | — | CN | disclosed |
| CN-113272421-B | Methods for producing tumor-infiltrating lymphocytes and their use in immunotherapy | 艾欧凡斯生物治疗公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113957088-B | Artificial design and application of intercellular communication system | 中国科学院微生物研究所 | 2025-02-18 | — | — | CN | disclosed |
| CN-112334486-B | Compositions and methods for treating cancer | 先天制药公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113166794-B | Method for quantifying phosphoethanolamine, oxidoreductase for quantification, composition for quantification, kit for quantification, and sensor for quantification | 龟甲万株式会社 | 2025-02-14 | — | — | CN | disclosed |
| CN-112516302-B | Anti-LAG-3 antibodies and anti-PD-1 antibodies in combination therapy for tumors | 百时美施贵宝公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-116745423-B | Heterologous peptide production based on fluorescent fusion | 斯坦陵布什大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-112823022-B | Multi-specific binding proteins that bind BCMA, NKG2D, and CD16 and methods of use | 蜻蜓治疗公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-116098986-B | Keratin 7 protein, recombinant plasmid expressing Keratin 7 protein, recombinant probiotics and application | 兰州大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-114525259-B | CD 7-targeting chimeric antigen receptor and uses thereof | 南京北恒生物科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-112739717-B | Trispecific antagonists | 璟尚生物制药公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-113015745-B | Antibodies to staphylococcus aureus leukotoxin | 免疫医疗有限责任公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-112708612-B | Redox enzyme electrode for enzyme electrocatalytic reduction, preparation method thereof and enzyme electrocatalytic reactor | 厦门大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-112390888-B | Stable formulations containing anti-PCSK 9 antibodies | 美国安进公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-108699541-B | Cancer of the human body | 神经生物有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-113248624-B | SYNTAC polypeptides and uses thereof | 阿尔伯特爱因斯坦医学院 | 2025-02-07 | — | — | CN | disclosed |
| CN-113272448-B | Large-scale parallel sequencing using unlabeled nucleotides | 深圳华大智造科技股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-113906140-B | A2/NY-ESO-1 specific T cell receptor and uses thereof | 路德维格癌症研究院 | 2025-01-28 | — | — | CN | disclosed |
| CN-113226472-B | Double immunocyte adapter | 雷维托普有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-114341179-B | Multimeric bispecific anti-CD 123 binding molecules and uses thereof | IGM生物科学股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-113301919-B | Bispecific antibodies that activate immune cells | JN生物科学有限责任公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-113166812-B | Preoperative risk stratification based on PDE4D7 and DHX9 expression | 皇家飞利浦有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-110612352-B | Recombinant host cells with altered membrane lipid composition | 贝林格尔·英格海姆RCV两合公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-116240246-B | Method for synthesizing calcitol by using peroxidase | 浙江金朗博药业有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-112292182-B | C-type natriuretic peptide grafted antibody | 勃林格殷格翰国际有限公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-112236197-B | Naolinatriuretic peptide grafted antibodies | 勃林格殷格翰国际有限公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-113121702-B | Multimeric delivery system for intracellular delivery of molecules | 厦门大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-112533948-B | Therapeutic antibodies that bind to double-antennal Lewis B and Lewis Y antigens | 台湾醣联生技医药股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-114206372-B | Pharmaceutical formulations of non-activated polypeptide TRP | 大都会生命科学有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-111344307-B | Bispecific antibodies that bind CD40 and EpCAM | 协和麒麟株式会社 | 2025-01-14 | — | — | CN | disclosed |
| CN-112218893-B | Anti-SIRPA antibodies and methods of use thereof | 艾利妥 | 2025-01-14 | — | — | CN | disclosed |
| CN-113652411-B | Cas9 protein, gene editing system containing Cas9 protein and application | 复旦大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-112908417-B | Gene excavation method combining functional sequence and structure simulation, NADH preference type glufosinate-ammonium dehydrogenase mutant and application | 浙江工业大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-112384532-B | Anti-SIRP-beta 1 antibodies and methods of use thereof | 艾利妥 | 2025-01-10 | — | — | CN | disclosed |
| CN-115109134-B | Application of alfalfa MsNRAMP protein in inhibiting tobacco mosaic virus | 哈尔滨师范大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-112840027-B | Enzymatic compositions for carbohydrate antigen cleavage, methods, uses, devices and systems related thereto | 不列颠哥伦比亚大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-114616326-B | Biosynthesis of cannabinoids from cannabigerolic acid using cannabinoid synthase | 新加坡国立大学 | 2025-01-10 | — | — | CN | disclosed |
| US-12187782-B2 | PDL1 peptides for use in cancer vaccines | IO BIOTECH APS (DK) | 2025-01-07 | — | — | US | disclosed |
| US-12188948-B2 | Metabolite biomarkers for diseases associated with the contact activation system | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-01-07 | — | — | US | disclosed |
| CN-113655228-B | Immunoassay method for detecting cleaved high molecular weight kininogen | 武田药品工业株式会社 | 2025-01-07 | — | — | CN | disclosed |
| CN-113166269-B | Multispecific binding constructs against checkpoint molecules and uses thereof | 指南针制药有限责任公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-109715189-B | Humanized monoclonal antibodies targeting VE-PTP (HPTP-beta) | 视点制药公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-112996814-B | Pharmaceutical combination of anti-CEACAM 6 and anti-PD-1 or anti-PD-L1 antibodies for the treatment of cancer | 拜耳公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-111527101-B | Photosynthetic organism gene regulation for improved growth | 合成基因组股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-114540316-B | Oncolytic virus and uses thereof | 上海荣瑞医药科技有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-111247249-B | DNA, polypeptide, anti-mesothelin antibody, tumor imaging agent and complex | 国立大学法人 冈山大学 | 2024-12-31 | — | — | CN | disclosed |
| US-12180288-B2 | Antibodies to canine interleukin-4 receptor alpha | INTERVET INC. (US) | 2024-12-31 | — | — | US | disclosed |
| CN-114907479-B | Anti-CD 112R antibodies and uses thereof | 上海君实生物医药科技股份有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113490747-B | Methods for improving genome engineering efficiency | 华威大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-114729041-B | High affinity nanobodies targeting B7H3 (CD 276) for the treatment of multiple solid tumors | 美国政府(由卫生和人类服务部的部长所代表) | 2024-12-31 | — | — | CN | disclosed |
| CN-119193339-A | Application of schizophyllum commune ergothioneine synthase genes ScEgt a and ScEgt b in synthesis of ergothioneine | 南京大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-113677403-B | Bispecific antigen binding molecules comprising lipocalin muteins | 豪夫迈·罗氏有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115896116-B | Subterranean termite gram negative bacteria recognition protein GNBP1 gene and application thereof | 南京林业大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-114901814-B | Monomeric polypeptides having hydrogenase activity, in particular recombinant monomeric polypeptides having hydrogenase activity | H2WIN 股份公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-113383072-B | Enzymatic production of hexoses | 博努莫斯股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-115380109-B | D-psicose 3-epimerase for bioconversion of D-fructose into D-psicose | 康纳根有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-110981957-B | Fc region variants with improved protein A binding | 豪夫迈·罗氏有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-117597451-B | Enhanced HMO formation by modifying intracellular lactose import | 帝斯曼知识产权资产管理有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-112567019-B | Microorganism producing polyunsaturated fatty acid and method for producing polyunsaturated fatty acid | 协和发酵生化株式会社 | 2024-12-20 | — | — | CN | disclosed |
| CN-113166245-B | SIRPalpha binding proteins and methods of use thereof | 细胞基因公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-109414426-B | Combination cancer immunotherapy with arginine depleting agents | 北极星药业集团股份有限公司 | 2024-12-20 | — | — | CN | disclosed |
| WO-2024257843-A1 | ZINC FINGER PROTEIN, ZINC FINGER NUCLEASE, VECTOR, AND GENOME EDITING METHOD USING SAID SUBSTANCES | 株式会社VC Gene Therapy | 2024-12-19 | — | — | WO | disclosed |
| CN-114621222-B | 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-112512581-B | Antibody constructs against CLDN18.2 and CD3 | 安进研发（慕尼黑）股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-111886246-B | Anti-TMEM 106B antibodies and methods of use thereof | 艾莱克特有限责任公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-113490506-B | Inactivated APXIA, APXIIA and APXIIIA toxins | 法国诗华大药厂 | 2024-12-13 | — | — | CN | disclosed |
| CN-115583995-B | Bispecific antibody and preparation method and application thereof | 立凌生物制药(苏州)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114945670-B | Base editing system and use method thereof | 苏州齐禾生科生物科技有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-112851808-B | IGF-1R antibodies and their use as targeting vectors for the treatment of cancer | 皮埃尔法布雷医药公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-113490850-B | Diagnostic and therapeutic methods for treating breast cancer | 基因泰克公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-115335120-B | Methods for inhibiting MASP-2 for the treatment and/or prevention of coronavirus-induced acute respiratory distress syndrome | 奥默罗斯公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-110856751-B | Therapeutic agents comprising nucleic acids and TCR-modified immune cells and uses thereof | 杭州康万达医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-113330033-B | Leukocyte immunoglobulin-like receptor 2 neutralizing antibodies | 先天制药公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114867751-B | 4-1BB and OX40 binding proteins, related compositions and methods, anti-4-1 BB antibodies, and anti-OX 40 antibodies | 阿帕特夫研究和发展有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114657166-B | Additional endoglucanase variants and methods | 福尼亚生物处理股份有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114502200-B | Antibody drug conjugates | 深圳康源久远生物技术有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-112739718-B | Anti-TNFRSF 9 antibodies and uses thereof | 祐和医药科技(北京)有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115073609-B | Recombinant protein based on African swine fever virus CD2v protein extracellular domain, construction method and application thereof | 湖南派智生物科技有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-114945594-B | Anti-LILRB 1 antibodies and uses thereof | 株式会社LG化学 | 2024-11-26 | — | — | CN | disclosed |
| CN-114173817-B | Cultured meat products using genetically modified cells | 塔夫茨大学信托人 | 2024-11-26 | — | — | CN | disclosed |
| CN-117377487-B | Transferrin binding antibodies and uses thereof | 领诺(上海)医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-116948030-B | Anti-ASGR 1 monoclonal antibody and application thereof | 武汉大学 | 2024-11-19 | — | — | CN | disclosed |
| CN-113166242-B | Combination therapy for cancer | 戊瑞治疗有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-110831669-B | Optogenetic induction of pathology of neurodegenerative diseases | 匹兹堡大学联邦高等教育系统 | 2024-11-19 | — | — | CN | disclosed |
| CN-114703167-B | Improved coagulation compositions | Q-塞拉有限公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-109844120-B | Resistance genes against plexiform root diseases | KWS种子欧洲股份公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-113637694-B | Compositions and methods for dengue virus chimeric constructs in vaccines | 武田疫苗股份有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-110959040-B | Base editor with improved precision and specificity | 通用医疗公司 | 2024-11-12 | — | — | CN | disclosed |
| US-12138295-B2 | Methods of treating Crohn's disease with anti-IL23 specific antibody | JANSSEN BIOTECH, INC. | 2024-11-12 | — | — | US | disclosed |
| CN-112786101-B | Preparation method of heat-stable antibody | 中国农业大学 | 2024-11-12 | — | — | CN | disclosed |
| US-12139535-B2 | Methods for upregulating immune responses using combinations of anti-RGMb and anti-PD-1 agents | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| CN-112334581-B | Method for biocatalytically producing terpene compounds | 弗门尼舍有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-112513092-B | DLL3/CD3 binding proteins for the treatment of cancer | 勃林格殷格翰国际有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-109988237-B | Checkpoint modulator antagonists | 璟尚生物制药公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-112972492-B | Inhibition of cytokine-induced SH2 proteins in NK cells | 沃尔特及伊莱萨霍尔医学研究院 | 2024-11-08 | — | — | CN | disclosed |
| CN-110573173-B | TERT immunogenic compositions and methods of treatment using the same | 宾夕法尼亚大学理事会 | 2024-11-08 | — | — | CN | disclosed |
| CN-111743923-B | Therapeutic agents comprising isolated recombinant oncolytic adenoviruses and immune cells and uses thereof | 北京康万达医药科技有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-12135329-B2 | Peptide quantitation assay for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-11-05 | — | — | US | disclosed |
| CN-111372950-B | VEGFR-antibody light chain fusion proteins | 免疫苏醒公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-114829402-B | Anti-ROR 1 antibody and preparation method and application thereof | 南京艾美斐生物医药科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-114045277-B | Base editor and construction method and application thereof | 复旦大学 | 2024-11-05 | — | — | CN | disclosed |
| CN-114929751-B | ROR1 specific chimeric antigen receptor and therapeutic application thereof | 南京艾美斐生物医药科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118878633-A | Application of multi-target peptide in preparing analgesic drug | 南通大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-114672553-B | Use of KRT15 in esophageal cancer auxiliary diagnosis and targeted therapy | 中国医学科学院肿瘤医院 | 2024-11-01 | — | — | CN | disclosed |
| CN-114901816-B | Lipase modified strains | 帝斯曼知识产权资产管理有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-114096672-B | WOX gene | 先正达农作物保护股份公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-112567042-B | Methods for enhancing genome engineering efficiency | 科沃施种子欧洲股份两合公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-113173990-B | Neutralizing anti-influenza b antibodies and uses thereof | 免疫医疗有限责任公司 | 2024-10-29 | — | — | CN | disclosed |
| US-12129489-B2 | Yarn for cell culture scaffold, ply yarn comprising same and fabric comprising the same | AMOGREENTECH CO., LTD. (KR) | 2024-10-29 | — | — | US | disclosed |
| CN-113899902-B | Method for identifying tyrosine phosphatase substrate | 上海科技大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118871122-A | Chaperones as autophagy receptors for clearing protein aggregates and/or aggregation-prone proteins | 清华大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-110997726-B | Compositions and methods for treating or preventing endocrine FGF-associated diseases | 耶鲁大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-112375145-B | Human anti-IFN-alpha antibody, IFN-alpha binding fragment, polynucleotide, composition, kit, application and preparation method | 因美诺克股份公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-114729049-B | Antigen binding proteins | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-112955547-B | Means and methods for increasing protein expression by using transcription factors | 贝林格尔·英格海姆RCV两合公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-110651189-B | Peptide vaccine | 特雷斯生物有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-113366112-B | Enzymatic production of tagatose | 博努莫斯股份有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-112358548-B | Human anti-IFN-alpha antibody, IFN-alpha binding fragment, polynucleotide, composition, kit, application and preparation method | 因美诺克股份公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-114957423-B | Application of ethylene insensitive protein GmEIN in improving phosphorus absorption and utilization rate of plants and promoting growth of plant root systems | 河南农业大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-118421604-B | Recombinant lysostaphin mutant and preparation method and application thereof | 小白鲸(中山)生物医药有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-112334168-B | Dermal fillers and uses thereof | 科尔普兰特有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-112074538-B | Antibodies and bispecific antigen binding molecules that bind HER2 and/or APLP2, conjugates and uses thereof | 瑞泽恩制药公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-114786773-B | Benzothiazaheterocycles Heptatriene compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-111936628-B | Alzheimer disease animal model and application thereof | 清华大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-114026226-B | Target-specific CRISPR mutants | 株式会社图尔金 | 2024-10-18 | — | — | CN | disclosed |
| CN-114058601-B | Enzyme with function of catalyzing glycolaldehyde to synthesize glycol and application thereof | 北京化工大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-112399854-B | Vaccine composition for preventing or treating diseases caused by severe fever with thrombocytopenia syndrome (SFTS) viral infection | 韩国科学技术院 | 2024-10-11 | — | — | CN | disclosed |
| CN-114478779-B | Humanized glypican 3 monoclonal antibody and application thereof | 华中农业大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-113637086-B | Compositions and methods for dengue virus chimeric constructs in vaccines | 武田疫苗股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113637693-B | Compositions and methods for dengue virus chimeric constructs in vaccines | 武田疫苗股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| US-20240336652-A1 | Peptide compounds targeting PD-1 receptor as well as preparation and applications thereof | UNIV NANTONG (CN) | 2024-10-10 | — | — | US | disclosed |
| CN-114072508-B | Novel lactic acid bacteria | 国际营养与健康丹麦有限公司 | 2024-10-08 | — | — | CN | disclosed |
| CN-112767998-B | Polypeptide vaccine composition aiming at targeted drugs of Darafenib, pembrolizumab, vemurafenib and semtinib and design method thereof | 杭州纽安津生物科技有限公司 | 2024-10-08 | — | — | CN | disclosed |
| US-20240327512-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF RETINAL DEGENERATION | DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN E.V. (DZNE) (DE) | 2024-10-03 | — | — | US | disclosed |
| CN-114555797-B | Biosynthesis of cannabinoid precursors using aromatic prenyl transferases | 新加坡国立大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-112759650-B | Modified J chain | IGM生物科学股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114921442-B | Enzyme variants and polynucleotides encoding same | 诺维信公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114716544-B | Complement component C5 antibodies | 阿勒根公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-113831417-B | Bispecific recombinant protein and application thereof | 上海津曼特生物科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-113614536-B | Detection of biomarkers for non-small cell lung cancer | 盛捷宁克斯私人有限公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-4433495-A1 | PEPTIDES AND USES THEREOF | Preveceutical Medical Inc. (CA) | 2024-09-25 | — | — | EP | disclosed |
| CN-112867799-B | Production of steviol glycosides by whole cell bioconversion | 马努斯生物合成股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-114450307-B | Genetically engineered cells and uses thereof | 苏州克睿基因生物科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-112543807-B | Fragmented GRS polypeptides, variants thereof and uses thereof | Curebio Therapeutics株式会社 | 2024-09-24 | — | — | CN | disclosed |
| CN-113637074-B | NKp46 antibody and preparation method and application thereof | 上海怀越生物科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-114040800-B | Killer lectin-like receptor subfamily G member 1 (KLRG 1) depleting antibodies | 阿波科有限责任公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-112534052-B | Novel IL-21 prodrugs and methods of use | 奥美药业有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-111094343-B | Antibody variants | 蒂洛特斯制药股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-111094347-B | Binding molecules that modulate biological activity expressed by cells | 美勒斯公司 | 2024-09-20 | — | — | CN | disclosed |
| US-20240310377-A1 | EVALUATION, ASSAYS AND TREATMENT OF PKALMEDIATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-09-19 | — | — | US | disclosed |
| CN-114585258-B | Bacterial compositions for controlling fungal spoilage and uses thereof | 科·汉森有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-111741976-B | FC binding fragments comprising PD-L1 antigen binding sites | 英沃克斯制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-111801109-B | Peptides capable of improving cognitive function | 一般财团法人粮食研究会 | 2024-09-17 | — | — | CN | disclosed |
| CN-110023331-B | Modified ligand-gated ion channels and methods of use | 霍华休斯医学研究院 | 2024-09-17 | — | — | CN | disclosed |
| CN-113666990-B | T cell vaccine immunogen for inducing broad-spectrum anti-coronavirus and application thereof | 复旦大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-114652853-B | Anti-IL-4R antibody-drug conjugate and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118647629-A | Immunoconjugates comprising TNF-alpha and methods and compositions related thereto | 苏州格治生物科技有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-109803981-B | Novel peptides and scaffolds for immunotherapy of squamous cell head and neck cancer and other cancers | 伊玛提克斯生物技术有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-112512550-B | TGF-beta receptor fusion protein pharmaceutical composition and application thereof | 苏州盛迪亚生物医药有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-20240301020-A1 | METHODS AND COMPOSITIONS FOR REGENERATING TISSUES | NellOne Therapeutics, Inc. (US) | 2024-09-12 | — | — | US | disclosed |
| US-20240301023-A1 | PEPTIDES AND USES THEREOF | PreveCeutical Medical Inc. (CA) | 2024-09-12 | — | — | US | disclosed |
| CN-116286562-B | Genetically engineered bacterium and preparation method and application thereof | 虹摹生物科技(上海)有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-109796532-B | Binding unit targeting fibroblast activation protein alpha and application thereof | 恺兴生命科技(上海)有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-110042114-B | Expression and secretion system | 弗·哈夫曼-拉罗切有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114107274-B | Preparation method of wool immobilized enzyme and wool immobilized enzyme column reactor | 厦门大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-112368012-B | Antibody variable domains targeting the NKG2D receptor | 蜻蜓疗法股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-109952112-B | CD123 binding proteins and related compositions and methods | 阿帕特夫研究和发展有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-115141806-B | Chimeric antigen receptor T cell targeting Her2 and expressing PD-L1 antibody, and preparation method and application thereof | 深圳宾德生物技术有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-113631582-B | Fusion protein and application thereof | 杭州尚健生物技术有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-111051332-B | Immunomodulators | 百时美施贵宝公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-111386282-B | T cell receptor recognizing mutated p53 | 美国卫生和人力服务部 | 2024-09-06 | — | — | CN | disclosed |
| CN-114269781-B | Combination of bispecific fusion proteins and anti-Her 2 antibodies for tumor treatment | 江苏康宁杰瑞生物制药有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-113151291-B | Methods for improving swine health by targeted inactivation of CD163 | 吉纳斯公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-115177728-B | Method for treating cancer caused by activation of MAPK/ERK pathway, application of cancer and CREPT-CDK9 complex | 清华大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-111133005-B | Programming cell death protein 1 antibodies | 奥古斯塔大学研究所公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-114712487-B | Use of disordered protein sequences for preventing biological contamination | 清华大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-113583131-B | Anti-TIGIT antibodies | 默沙东有限责任公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-111386284-B | Chimeric phagocytic receptor molecules and methods of use | 森罗治疗公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114364704-B | Modified PIGGYBAC transposase polypeptides, polynucleotides encoding same, introduction vectors, kits, methods of integrating target sequences into the genome of cells, and methods of producing cells | 株式会社东芝 | 2024-08-30 | — | — | CN | disclosed |
| CN-112805297-B | Anti-human PD-L1 antibodies and uses thereof | 财团法人生物技术开发中心 | 2024-08-30 | — | — | CN | disclosed |
| CN-115449521-B | Binary vector for simultaneously expressing insect-resistant gene and herbicide-resistant gene and application thereof | 杭州芳韵生物科技有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114423871-B | Template-free enzymatic synthesis of polynucleotides using poly (A) and poly (U) polymerases | DNA斯克瑞普特公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114470193-B | Antibody agents specific for human CD19 and uses thereof | 优瑞科生物技术公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-115667317-B | Fully human targeted CD19 and CD22 bispecific antigen chimeric receptor and application thereof | 南京驯鹿生物技术股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| US-20240287142-A1 | RECOMBINANT ADENOVIRUSES AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-08-29 | — | — | US | disclosed |
| CN-113652430-B | Light-operated RNA metabolism regulation and control system | 华东理工大学 | 2024-08-27 | — | — | CN | disclosed |
| CN-118556071-A | Saccharide binding polypeptides of sarcandra glabra | 化学、工艺学和冶金学院 | 2024-08-27 | — | — | CN | disclosed |
| CN-112175093-B | Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests | 孟山都技术有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-112142858-B | Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests | 孟山都技术有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-110290804-B | Capsular polysaccharide vaccine of Klebsiella pneumoniae | 王锦堂 | 2024-08-27 | — | — | CN | disclosed |
| CN-112175094-B | Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests | 孟山都技术有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-111433223-B | Freeze-dried preparation of antithyroid transthyretin monoclonal antibody | 诺和诺德A/S（股份有限公司） | 2024-08-27 | — | — | CN | disclosed |
| CN-112409483-B | Anti-PD-L1 nanobody | 浙江道尔生物科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-112142857-B | Chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests | 孟山都技术有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-110944667-B | Antibody-drug conjugate formulations and lyophilization thereof | 第一三共株式会社 | 2024-08-27 | — | — | CN | disclosed |
| CN-118541380-A | Protein conjugate with multiple loads and preparation method thereof | 岩唐生物科技(杭州)有限责任公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-111867628-B | Anti-CD 73 antibodies and uses thereof | 凡恩世制药(北京)有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-115335370-B | Fibroblast activator protein ligand for targeted delivery applications | 菲洛谢姆股份公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-113454100-B | HIV vaccine immunogens | 洛克菲勒大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-112912395-B | Anti-GDF 15 antibodies, compositions, and methods of use | 辉瑞公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-113677709-B | Antibodies to ligand-1 (PD-L1) of apoptosis protein and uses thereof | 斯克里普斯抗体研究所 | 2024-08-23 | — | — | CN | disclosed |
| US-20240277825-A1 | Recombinant Mycobacterium as an Immunotherapeutic Agent for the Second-Line Therapy of Bladder Carcinoma | SERUM LIFE SCIENCE EUROPE GMBH (DE) | 2024-08-22 | — | — | US | disclosed |
| CN-111108122-B | Antibody variants | 蒂洛特斯制药股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-113528483-B | SHP2 specific inactivating mutant proteins and their use in CAR-T therapy | 复星凯特生物科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-113403293-B | Polymerase compositions and methods of making and using the same | 生命技术公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20240271211-A1 | RNA BIOMARKERS FOR HEREDITARY ANGIOEDEMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-08-15 | — | — | US | disclosed |
| CN-113563462-B | Neutralizing anti-influenza b antibodies and uses thereof | 免疫医疗有限责任公司 | 2024-08-13 | — | — | CN | disclosed |
| US-12061206-B2 | Diagnosis and treatment of autoimmune diseases | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-08-13 | — | — | US | disclosed |
| CN-112225812-B | Novel antibodies that bind TFPI and compositions comprising same | 财团法人牧岩生命科学研究所 | 2024-08-13 | — | — | CN | disclosed |
| CN-113784728-B | Bispecific T cell conjugates with cleavable cytokines for targeted immunotherapy | 深圳康源久远生物技术有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-112424228-B | Novel bispecific agonistic 4-1BB antigen binding molecules | 豪夫迈·罗氏有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-112955468-B | Bispecific antigen binding molecules comprising anti-FAP clone 212 | 豪夫迈·罗氏有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-114716567-B | Preparation method and application of chimeric antigen and preparation for resisting bungarose venom | 上海赛伦生物技术股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-112513093-B | Novel antibody and preparation method and application thereof | 奥美药业有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-110462024-B | MR 1-restricted T cell receptor for cancer immunotherapy | 巴塞尔大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118440915-A | Manganese peroxidase ThMnP for degrading vomitoxin, coding gene and application | 四川农业大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-114341158-B | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-109862912-B | Adenovirus carrying dual specificity T cell adapter | 阿卡米斯生物公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118421604-A | Recombinant lysostaphin mutant and preparation method and application thereof | 小白鲸(中山)生物医药有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-111187338-B | Modulation of complement activity | RA制药公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-115216488-B | Method for creating large-long-grain novel germplasm of rice or large-long-grain novel germplasm of short stalk and application thereof | 中国种子集团有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-111542548-B | DPP3 binding agents directed against and binding to specific DPP3 epitopes and their use in the prevention or treatment of diseases/acute conditions associated with oxidative stress | 4TEEN4制药有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-113825774-B | Anti-CD 47/anti-PD-L1 multi-antigen binding proteins and methods of use thereof | 南京金斯瑞生物科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-115074372-B | Recombinant African swine fever virus J18L subunit protein and preparation method and application thereof | 浙江海隆生物科技股份有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-111235245-B | Method of | 牛津纳米孔科技公开有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114072673-B | Cell-based methods for determining botulinum toxin activity | 秀杰股份公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-111778263-B | Compositions and methods for dengue virus chimeric constructs in vaccines | 武田疫苗股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-113943745-B | Synthesis method and application of abnormal coccus lutein | 中国农业科学院生物技术研究所 | 2024-07-26 | — | — | CN | disclosed |
| CN-114456994-B | Recombinant staphylococcus aureus for preparing bacterial membrane vesicle multi-linked vaccine as well as preparation method and application thereof | 中国人民解放军陆军军医大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-115112892-B | Methods, uses and kits for determining surgical margins of cancer | 清华大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-114807175-B | Monosaccharide transgene OsSTP, transporter thereof, application of monosaccharide transgene OsSTP in improving rice yield and amplification primer | 湖南农业大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-113272330-B | Bispecific antibody | 南通壹宸生物医药科技有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-118401251-A | Recombinant mycobacterium as immunotherapeutic agent for two-line treatment of bladder cancer | 欧洲血清生命科学有限公司 | 2024-07-26 | — | — | CN | disclosed |
| US-20240247071-A2 | Compositions and Methods for Enhancing Body Weight and Lean Muscle Mass Using Antagonists Against Leptin Receptor, GDF8 and Activin A | REGENERON PHARMACEUTICALS, INC. | 2024-07-25 | — | — | US | disclosed |
| CN-114364793-B | HPPD mutant protein with herbicide resistance and application thereof | 江苏省农业科学院 | 2024-07-23 | — | — | CN | disclosed |
| CN-115212309-B | Methods, uses and medicaments for preventing cancer recurrence, inhibiting or reversing normal tissue inflammation and canceration | 清华大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-112135624-B | Anti-CD 63 antibodies, conjugates and uses thereof | 瑞泽恩制药公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-114748618-B | Pharmaceutical formulation comprising bispecific antibodies against rabies virus G protein and method for preparing same | 重庆智翔金泰生物制药股份有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-109715203-B | Means and methods for treating HSV | 雷德生物科技股份公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-114206930-B | Methods and compositions directed against anti-CD 73 antibodies and variants | 上海复宏汉霖生物技术股份有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-111279024-B | Dynamic human heavy chain antibody libraries | 天演药业公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-113853388-B | Anti-EGFRVIII antibodies and antigen binding fragments thereof | 加拿大国家研究委员会 | 2024-07-19 | — | — | CN | disclosed |
| CN-111303244-B | Personalized immunotherapy of several neuronal and brain tumors | 伊玛提克斯生物技术有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829610-B | Method for improving photosynthetic organisms | 农牧研究公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114786682-B | Fibronectin type III domain binding CD71 | ARO生物疗法公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114774384-B | Taq DNA polymerase mutant and screening method thereof | 浙江大学杭州国际科创中心 | 2024-07-16 | — | — | CN | disclosed |
| CN-111556751-B | Modified ligand-gated ion channels and methods of use | 霍华休斯医学研究院 | 2024-07-12 | — | — | CN | disclosed |
| CN-110536703-B | Combination therapy using anti-AXL antibody-drug conjugates | ADC治疗有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114585731-B | Mutant hydroxyphenylpyruvate dioxygenase polypeptide, encoding gene and application thereof | 北京大北农生物技术有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-112770769-B | Multispecific binding proteins that bind HER2, NKG2D and CD16 and methods of use thereof | 蜻蜓疗法股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114364695-B | Antibodies specifically recognizing C5A and uses thereof | 舒泰神（北京）生物制药股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-116554343-B | Long-acting recombinant human growth hormone and application thereof | 领诺(上海)医药科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-116135981-B | Method for synthesizing malonic acid and application | 中国科学院天津工业生物技术研究所 | 2024-07-12 | — | — | CN | disclosed |
| CN-114316045-B | Anti-PD-L1 antibodies and uses thereof | 英诺欧奇生物医药(苏州)有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-113166746-B | Fusion proteins | 生化酶股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114846136-B | Recombinant factor G derived from horseshoe crab and method for assaying beta-glucan using the same | 富士胶片株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-114787347-B | Novel MAD nucleases | 因思科瑞普特公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20240230678-A1 | P53 POST-TRANSLATIONAL MODIFICATIONS AS MARKERS IN THE DIAGNOSIS AND PROGNOSIS OF A NEURODEGENERATIVE DISEASE | Diadem S.p.A. (IT) | 2024-07-11 | — | — | US | disclosed |
| WO-2024148357-A2 | U-P53 PEPTIDES AS MARKERS IN THE RATE OF PROGRESSION OF COGNITIVE DECLINE TO ALZHEIMER'S DISEASE | DIADEM SPA (IT) | 2024-07-11 | — | — | WO | disclosed |
| CN-109843929-B | Proteolytically cleavable chimeric polypeptides and methods of use thereof | 加利福尼亚大学董事会 | 2024-07-05 | — | — | CN | disclosed |
| CN-112955463-B | Anti-CXCR 2 antibodies and uses thereof | 赛福伦有限责任公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113025597-B | Improved genome editing system | 中国科学院微生物研究所 | 2024-07-05 | — | — | CN | disclosed |
| CN-112805068-B | Antibodies targeting CD137 and methods of use thereof | 努玛治疗有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-111615555-B | Transformed microorganism for producing copolymerized PHA comprising 3HH monomer unit with high composition ratio, and method for producing PHA based on the transformed microorganism | 株式会社钟化 | 2024-07-05 | — | — | CN | disclosed |
| CN-112262156-B | Anti-HER 2 antibodies | 新加坡科技研究局 | 2024-07-05 | — | — | CN | disclosed |
| CN-111741979-B | Her 2-targeted antigen binding molecules comprising 4-1BBL | 豪夫迈·罗氏有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114423779-B | Foot-and-mouth disease virus vaccine composition | 株式会社准绳生命科学 | 2024-07-02 | — | — | CN | disclosed |
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| CN-112262130-B | Crystal modifier of ondoxicam | 阿尔比里奥公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115124621-B | PD-L1 targeted nano antibody and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-02 | — | — | CN | disclosed |
| CN-114699518-B | Foot-and-mouth disease vaccine | 硕腾服务有限责任公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114729031-B | Anti-oncolytic viral antigen antibodies and methods of use thereof | 艾德梅尔治疗协会 | 2024-07-02 | — | — | CN | disclosed |
| CN-112638415-B | Compositions and methods for imaging | 大有华夏生物医药集团有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114958682-B | Use of Rennoborn hol-de la in the preparation of a product for inducing systemic resistance in plants or seeds thereof | 慕恩（广州）生物科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114853911-B | Trefoil factor 2/interferon alpha 2 fusion and application thereof in preventing and treating viral infectious diseases | 复旦大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-114616247-B | OX40/PD-L1 bispecific antibodies | 江苏康宁杰瑞生物制药有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-116554324-B | Antibody capable of specifically recognizing 4-1BB, preparation method and application thereof | 三优生物医药(上海)有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114375342-B | Improved virus detection method | 东洋纺株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-113785052-B | Novel recombinant diamine oxidase and its use for treating diseases characterized by excess histamine | 维也纳兽医大学 | 2024-06-28 | — | — | CN | disclosed |
| EP-4388003-A1 | ANTIGEN-BINDING POLYPEPTIDES AGAINST CD39 | Universitätsklinikum Hamburg-Eppendorf (DE) | 2024-06-26 | — | — | EP | disclosed |
| CN-114410625-B | RNA-guided DNA cleavage by Cas9-crRNA complex | 维尔纽斯大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-111670051-B | Biomolecular conjugates and uses thereof | 亚飞（上海）生物医药科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-111032695-B | ADAMTS-binding immunoglobulins | 默克专利股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114269398-B | Method for isolating spider silk proteins by high shear dissolution | 保尔特纺织品公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118251420-A | Humanized chimeric bovine antibodies and methods of use | 米诺陶治疗公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117186224-B | Anti-CD 40 antibodies | 明济生物制药（北京）有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-112770767-B | Specific bifunctional BY-001 (active ingredient combined BY homo-multimers of chimeric protein PD-L1/Fc-gamma 1) for down-regulating activation of human immune cells and application thereof | 陆云彪 | 2024-06-25 | — | — | CN | disclosed |
| CN-114805496-B | Group of non-ribosomal polypeptide (NRPs) compounds, preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-113929782-B | Neutralization of inhibitory pathways in lymphocytes | 依奈特制药公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-111601883-B | Amplification of TIL from fine needle aspirates and small biopsies | 艾欧凡斯生物治疗公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-111534504-B | Method of ligating one or more polynucleotide binding proteins to a target polynucleotide | 牛津纳米孔科技公开有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-112513639-B | Compositions and methods for imaging | 大有华夏生物医药集团有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115010812-B | Multimeric of African swine fever antigen-mediated cellular immunity and application thereof | 河南省龙星生物科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118215409-A | Cell culture method | 国际营养与健康丹麦私人有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113785039-B | Polypeptides having beta-glucanase activity, polynucleotides encoding same and use thereof in cleaning and detergent compositions | 诺维信公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-114426962-B | T-PA purification method | 佛山汉腾生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113227151-B | Anti-HER 2/PD1 bispecific antibodies | 三生国健药业（上海）股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118215678-A | Combination dosage regimen of CD137 and PD-L1 binding agent | 健玛保 | 2024-06-18 | — | — | CN | disclosed |
| CN-111819278-B | Novel psicose-6-phosphate phosphatase and use thereof | CJ第一制糖株式会社 | 2024-06-18 | — | — | CN | disclosed |
| CN-114557450-B | Use of early picked rice fruits for preparing slimming and probiotic composition | 大江生医股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-110536901-B | Antibodies that bind myelin oligodendrocyte glycoprotein | 协和麒麟株式会社 | 2024-06-18 | — | — | CN | disclosed |
| CN-115073588-B | Method for improving safety of drugs containing immunoglobulin Fc fragment | 中山康方生物医药有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-110129344-B | Improved thymidine kinase gene | 吉恩维沃公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118201618-A | Combination therapy with BCMA-directed T cell therapy | 细胞基因公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-113481218-B | Construction method of giant virus or giant phage derived aminoacyl tRNA synthetase/tRNA orthogonal system and orthogonal system | 中国药科大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-113795502-B | CD80 variant proteins and uses thereof | 轩竹生物科技股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111868238-B | Efficient and effective incorporation of DNA polymerase for methylation-dNTPs | 豪夫迈·罗氏有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-110546277-B | Diagnostic and therapeutic methods for cancer | 豪夫迈·罗氏有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114214340-B | Rice grain weight related gene, protein, molecular marker and application | 中国水稻研究所 | 2024-06-11 | — | — | CN | disclosed |
| CN-106459206-B | Immune-activating antigen binding molecules | 中外制药株式会社 | 2024-06-07 | — | — | CN | disclosed |
| CN-111837039-B | Tumor marker and method for recovering and detecting tumor cells by distinguishing tumor cells from inclusion cells | 东曹株式会社 | 2024-06-07 | — | — | CN | disclosed |
| CN-113929757-B | Method for enhancing cold tolerance of rice by mutating calcium ion binding protein OsCIP1/2 | 中国科学院植物研究所 | 2024-06-07 | — | — | CN | disclosed |
| CN-115772507-B | Application of cytochrome P450 enzyme in synthesis of ganoderma lucidum triterpene | 中国科学院天津工业生物技术研究所 | 2024-06-07 | — | — | CN | disclosed |
| CN-111511766-B | Modified anti-SIRPa antibodies and uses thereof | OSE免疫疗法 | 2024-06-07 | — | — | CN | disclosed |
| CN-114129708-B | Application of INVS protein in preparing medicament for repairing heavy metal-induced testis injury | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 2024-06-07 | — | — | CN | disclosed |
| CN-114044827-B | Low ADCC/CDC functional monoclonal antibody and preparation method and application thereof | 北京天成新脉生物技术有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114478795-B | Fusion protein for improving stability of oral administration of polypeptide drugs and application thereof | 安徽新熙盟生物科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114174331-B | Antibodies that bind to human metapneumovirus fusion proteins and uses thereof | 佐治亚大学研究基金会有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114605509-B | YH 66-01475 protein and application of encoding gene thereof in regulating and controlling bacterial arginine yield | 宁夏伊品生物科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-111770993-B | Modulation of CSR systems to produce lysine and lysine-derived products | 上海凯赛生物技术股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118119706-A | Polypeptides having D-psicose 3-epimerase activity | 安布罗西亚生物公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-116023503-B | Fusion protein and preparation method and application thereof | 上海交通大学 | 2024-05-31 | — | — | CN | disclosed |
| EP-4373519-A1 | RECOMBINANT MYCOBACTERIUM AS AN IMMUNOTHERAPEUTIC AGENT FOR THE SECOND-LINE THERAPY OF BLADDER CARCINOMA | Serum Life Science Europe GmbH (DE) | 2024-05-29 | — | — | EP | disclosed |
| CN-115216455-B | Application of ENB1 gene and encoding protein thereof in regulation and control of plant grain size and grain weight | 中国农业大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118103523-A | Method of | 牛津纳米孔科技公开有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118076233-A | Preparation of a plant-based fermentation product employing a combination of a microorganism and a protease, preferably a metalloprotease | 国际N&H丹麦有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-110177571-B | Engineered antibodies and uses thereof | 加利福尼亚大学董事会 | 2024-05-24 | — | — | CN | disclosed |
| CN-114679910-B | Polypeptides for treating pathologic thrombosis | 免疫功坊股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-114716552-B | Humanized, mouse or chimeric anti-CD 47 monoclonal antibodies | 四十七公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113195542-B | CD 30-binding moieties, chimeric antigen receptors and uses thereof | 南京传奇生物科技有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-110168105-B | System and method for sequencing T cell receptors and uses thereof | 瑞泽恩制药公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240166728-A1 | ANTIGEN BINDING PROTEINS | VIIV Healthcare UK (No.5) Limited (GB) | 2024-05-23 | — | — | US | disclosed |
| CN-114645059-B | Caragana microphylla drought-tolerant gene Chr8.226 and application thereof in preparation of drought-tolerant transgenic plants | 内蒙古农业大学 | 2024-05-21 | — | — | CN | disclosed |
| CN-114829400-B | Anti-PD-L1 antibodies | 森特萨制药(英国)有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114107275-B | Enzyme immobilization carrier and preparation method thereof, immobilized enzyme and preparation method thereof | 辽宁凯莱英医药化学有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114349832-B | Application of calmodulin binding protein COLD13 in regulation and control of plant COLD tolerance | 中国科学院植物研究所 | 2024-05-17 | — | — | CN | disclosed |
| CN-115074331-B | PSCA-targeted chimeric antigen receptor | 希望之城公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-113969268-B | Glu/Leu/Phe/Val dehydrogenase mutant and application thereof in preparation of L-glufosinate | 永农生物科学有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-112442128-B | Anti-phospholipase D4 antibodies | SBI生物技术有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115322248-B | Potassium ion channel protein AlAKT1, coding gene and application thereof | 大连理工大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-106574239-B | Microorganism of the genus Escherichia producing L-tryptophan and method for producing L-tryptophan using the same | CJ第一制糖株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-112204137-B | Stabilized cellulase variants | 诺维信公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113122521-B | Polypeptides having lipase activity and uses thereof | 丰益国际有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-109837315-B | Method for producing target substance | 味之素株式会社 | 2024-05-14 | — | — | CN | disclosed |
| CN-112272701-B | Stabilized cellulase variants | 诺维信公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113667676-B | Corn event MIR162 | 先正达参股股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-112384629-B | Method for enzymatic sulfonylation of alcohols and amines using enterobacteriaceae | 味之素株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-118019762-A | Dosage regimen for protein therapeutics | 阿帕特夫研究和发展有限公司 | 2024-05-10 | — | — | CN | disclosed |
| WO-2024094690-A1 | ANTIGEN BINDING PROTEINS | VIIV Healthcare UK (No.5) Limited (GB) | 2024-05-10 | — | — | WO | disclosed |
| CN-114907271-B | Compositions of benzamide and active compounds and methods of use thereof | 转化药物开发有限责任公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-108430497-B | Sugar-targeted therapeutic agents | 洛桑聚合联合学院 | 2024-05-07 | — | — | CN | disclosed |
| CN-114807063-B | Aflatoxin hydrolase, encoding gene thereof, recombinant vector, recombinant bacterium and application | 江西省科学院生物资源研究所 | 2024-05-07 | — | — | CN | disclosed |
| CN-117999099-A | Compositions for inhibiting angiotensin converting enzyme 2 (ACE 2) and/or TMPRSS2 expression | 仿生技术支持有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-114341178-B | Antibodies and assays for CCL14 | 机敏医药股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-113912717-B | EGFL 6-specific monoclonal antibodies and methods of use thereof | 得克萨斯大学体系董事会 | 2024-05-03 | — | — | CN | disclosed |
| CN-110997714-B | Multispecific binding molecules with specificity for dystrophin proteoglycans and laminin-2 | 赛诺菲 | 2024-05-03 | — | — | CN | disclosed |
| CN-111699003-B | Anti-LRP 5/6 antibodies and methods of use | 瑟罗泽恩奥普瑞汀公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113249345-B | Herbicide-resistant polypeptide, nucleic acid and application thereof | 山东舜丰生物科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115521942-B | Construction method and application of BVDV epitope gene vaccine | 天津市农业科学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-113969269-B | D-amino acid oxidase mutant and application thereof in preparation of L-glufosinate | 永农生物科学有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113930457-B | Method for synthesizing (S) -citronellol by double enzyme coupling | 浙江工业大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-114540399-B | Method for preparing L-valine, and gene mutant and biological material used by same | 宁夏伊品生物科技股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114250237-B | Tyrosine phenol lyase mutant, engineering bacterium and application thereof in catalytic synthesis of levodopa | 浙江工业大学 | 2024-05-03 | — | — | CN | disclosed |
| US-20240142468-A1 | PROTEIN BIOMARKERS FOR DISEASES ASSOCIATED WITH THE CONTACT ACTIVATION SYSTEM | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-05-02 | — | — | US | disclosed |
| CN-117956903-A | Modified antimicrobial peptides | 唐纳德丹福斯植物科学中心 | 2024-04-30 | — | — | CN | disclosed |
| CN-111699252-B | Endoglucanase compositions and methods | 福尼亚生物处理股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-110799536-B | Anti-SIRP alpha antibodies | 拜奥迪斯私人有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115702926-B | Application of Versican protein in preparation of medicines for repairing after myocardial injury | 中国医学科学院阜外医院 | 2024-04-26 | — | — | CN | disclosed |
| CN-113249343-B | Polypeptides, nucleic acids having herbicide-resistant properties and uses thereof | 山东舜丰生物科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-110312523-B | Anti-PD 1 and anti-CTLA 4 antibodies | 齐鲁皮吉特湾生物治疗有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-114341159-B | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-111108126-B | Serum albumin binding agent | 非营利性组织佛兰芒综合大学生物技术研究所 | 2024-04-26 | — | — | CN | disclosed |
| CN-113957063-B | Preparation method of mannanase mixture and application of mannanase mixture in konjak beverage | 五峰杰成魔芋食品有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-114075558-B | WH54 polymerase and application thereof in RT-PCR | 深圳华大生命科学研究院 | 2024-04-26 | — | — | CN | disclosed |
| CN-117229409-B | Anti-phencyclidine antibody, reagent for detecting phencyclidine and kit | 东莞市朋志生物科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| US-11965884-B2 | Method of quantitating unbound C5 in a sample | ALEXION PHARMACEUTICALS, INC. (US) | 2024-04-23 | — | — | US | disclosed |
| CN-114656565-B | Anti-PD-L1 antibody and application thereof | 广东菲鹏制药股份有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-114206946-B | Coronavirus vaccine compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-113337488-B | Isolated Cas13 protein | 中国科学院分子细胞科学卓越创新中心 | 2024-04-19 | — | — | CN | disclosed |
| CN-117916382-A | Gene therapy for yellow spot disease of ocular fundus (ABCA 4) | 马萨诸塞大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-110650974-B | Radiolabeled anti-LAG 3 antibodies for immune-PET imaging | 瑞泽恩制药公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117915948-A | Anti-TGF-beta antibody formulations and uses thereof | 建新公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-112679590-B | Related protein AtMYBS1 for regulating and controlling plant heat resistance, and coding gene and application thereof | 河南省新乡市农业科学院 | 2024-04-19 | — | — | CN | disclosed |
| EP-4354146-A2 | IMMUNOASSAY FOR THE DETECTION OF CLEAVED HIGH MOLECULAR WEIGHT KININOGEN | Takeda Pharmaceutical Company Limited (JP) | 2024-04-17 | — | — | EP | disclosed |
| CN-114574459-B | Glycogen branching enzyme mutant with improved catalytic activity and application thereof | 中国科学院天津工业生物技术研究所 | 2024-04-16 | — | — | CN | disclosed |
| CN-111629761-B | Exosomes for target-specific delivery and methods for preparing and delivering the exosomes | 伊利亚斯生物制品有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-115038787-B | Novel branched-chain amino acid aminotransferase variant and leucine production method using the same | CJ第一制糖株式会社 | 2024-04-12 | — | — | CN | disclosed |
| CN-111601888-B | Composition for preparing tagatose and method for preparing tagatose using the same | CJ第一制糖株式会社 | 2024-04-12 | — | — | CN | disclosed |
| CN-110621698-B | Combination therapies targeting PD-1, TIM-3 and LAG-3 | 法国施维雅药厂 | 2024-04-12 | — | — | CN | disclosed |
| CN-113106114-B | Factor for regulating expression efficiency of trichoderma reesei protein, regulating method and application | 中国科学院分子植物科学卓越创新中心 | 2024-04-12 | — | — | CN | disclosed |
| CN-117881699-A | anti-SIRP alpha antibodies | 勃林格殷格翰国际有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114846146-B | Engineered guide RNAs for increasing efficiency of CRISPR/Cas12f1 systems and uses thereof | 基恩科雷有限责任公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-114671947-B | High-affinity nano antibody for surface S protein of different subtypes of hepatitis B virus and application thereof | 中国科学院生物物理研究所 | 2024-04-09 | — | — | CN | disclosed |
| CN-114774477-B | Method for producing ethanol using recombinant yeast | 丰田自动车株式会社 | 2024-04-09 | — | — | CN | disclosed |
| CN-117858721-A | Antibodies for the treatment of alpha-synucleinopathies | ABL生物公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117858719-A | Methods of dosing and treatment using a combination of checkpoint inhibitor therapy and CAR T cell therapy | 朱诺治疗学股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-112789505-B | Biosynthetic platforms for the production of cannabinoids and other prenylated compounds | 加利福尼亚大学董事会 | 2024-04-09 | — | — | CN | disclosed |
| CN-114786772-B | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117858945-A | Modification of HECT E3 ubiquitin ligase gene for improved yield traits | 成对植物服务股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-114806984-B | Genetically engineered bacterium EC01S7 for co-producing 3-hydroxypropionic acid and 1, 3-propanediol, construction method and application | 江苏大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117836308-A | Means and methods for selecting specific binding agents | 非营利性组织佛兰芒综合大学生物技术研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-111010875-B | Methods for modulating immune responses | 库尔生物制药有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-110945022-B | Plasmodium sporozoite NPDP peptides as vaccine and novel malaria vaccine and antibody binding targets | 生物医学研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-110650975-B | Bicistronic chimeric antigen receptor and uses thereof | 美国卫生和人力服务部 | 2024-04-05 | — | — | CN | disclosed |
| CN-110869488-B | Enhanced metabolite producing yeast | 安迪苏法国联合股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-110678757-B | Method for diagnosing or monitoring renal function or diagnosing renal dysfunction | 斯弗因高泰克有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-112795554-B | Low temperature resistant cellulase mutants | 潍坊康地恩生物科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117836322-A | Human neutralizing monoclonal antibodies against SARS-CoV-2 and uses thereof | 巴斯德研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-114540329-B | Lactase mutant | 潍坊康地恩生物科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117813111-A | Treatment of peanut allergy with tolerating nanoparticles | 库尔制药开发公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117813319-A | Nanocarriers based on extracellular vesicles | 俄亥俄州立创新基金会 | 2024-04-02 | — | — | CN | disclosed |
| CN-117813379-A | Gene editing system comprising CRISPR nucleases and uses thereof | 阿伯生物技术公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-110785180-B | Oncolytic viral therapy and immunotherapy | 贝勒医学院 | 2024-04-02 | — | — | CN | disclosed |
| US-11946031-B2 | Yarn for cell culture scaffold and fabric comprising the same | AMOGREENTECH CO., LTD. (KR) | 2024-04-02 | — | — | US | disclosed |
| CN-117795065-A | Gene editing in primary immune cells using cell penetrating CRISPR-CAS system | 宾夕法尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| CN-117794358-A | Methods and compositions for enhancing root development | 成对植物服务股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115261353-B | DNA polymerase with adjustable pyrophosphorylase activity and preparation method thereof | 厦门通灵生物医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114805600-B | VLPs of porcine circovirus type 2d frame chimeric antigen epitope of porcine foot-and-mouth disease virus, and preparation method and application thereof | 华南农业大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-117795062-A | Multimeric proteins of the peroxide reductase family as scaffold proteins | 卡萨丽泽公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115261351-B | Reverse transcription-polymerization bifunctional enzyme and preparation method and application thereof | 厦门通灵生物医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-111044725-B | Evaluation and treatment of bradykinin-mediated disorders | 武田药品工业株式会社 | 2024-03-29 | — | — | CN | disclosed |
| CN-111629752-B | Pharmaceutical composition for preventing or treating cell migration-related diseases, comprising antibody specifically binding to N-terminus of lysyl-tRNA synthetase as active ingredient | 塞梅蒂股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-111187799-B | Method for producing red algae glucoside and special engineering bacterium thereof | 南京盛德生物科技研究院有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110234661-B | Radiolabeled anti-PD-L1 antibodies for use in immunoPET imaging | 瑞泽恩制药公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110997903-B | Method of activating T cells for cancer treatment | 古德T细胞有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114085849-B | Herbicide resistance protein, gene and use | 青岛清原种子科学有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117795066-A | Systems, methods, and components for RNA-guided effector recruitment | 纽约市哥伦比亚大学理事会 | 2024-03-29 | — | — | CN | disclosed |
| CN-110546163-B | anti-TIGIT antigen binding proteins and methods of use thereof | 波坦察治疗学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114480465-B | Bacillus subtilis for producing 2' -fucosyllactose and application thereof | 江南大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-117769565-A | Fusion proteins and their use in the treatment of membranous nephropathy | 基洛米特罗罗索有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-114350631-B | Glufosinate dehydrogenase mutant, engineering bacteria, immobilized cells and application | 浙江工业大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-113646328-B | Immunocytokine and preparation and application thereof | 南通壹宸生物医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-113544265-B | Novel psicose-6-phosphatase, composition for preparing psicose comprising the same, and method for preparing psicose using the same | CJ第一制糖株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-117769596-A | Amylase polypeptides with improved properties | 杜邦营养生物科学有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115043947-B | Crimedes-Congo hemorrhagic fever virus Zera-Gn protein nanoparticle, preparation method and application thereof | 宁夏大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-112759647-B | anti-PD-L1 antibody and pharmaceutical application thereof | 上海宏成药业有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-110612113-B | Gene therapy for haploid insufficiency | 加利福尼亚大学董事会 | 2024-03-26 | — | — | CN | disclosed |
| CN-117769602-A | Recombinant microorganism and method for producing L-leucine using same | 绿色地球研究所株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-113316587-B | Bispecific molecule and preparation and application thereof | 南通壹宸生物医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-114507275-B | Application of OsOSM1 protein and encoding gene thereof in regulation and control of low-temperature tolerance of plants | 中国科学院植物研究所 | 2024-03-22 | — | — | CN | disclosed |
| CN-111183220-B | Tool for glycan analysis | 杰诺维斯公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117750978-A | Synthetic peptide shuttle bioconjugates for intracellular cargo delivery | 费尔丹生物公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116457463-B | anti-OX 40 antibodies, pharmaceutical compositions and uses thereof | 上海泰槿生物技术有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117750963-A | Novel cell therapy system | 生物权威(澳大利亚)有限责任公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-111465686-B | Animal cell, method for producing animal cell, and method for producing target protein | 富士胶片株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-114262377-B | Preparation method of anti-human CD70 nano antibody for blocking binding of CD70 and ligand CD27 thereof and coding sequence thereof | 新疆优迈生物技术有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116419970-B | Low toxicity anti-OX 40 antibodies, pharmaceutical compositions and uses thereof | 中山恒动生物制药有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-111601892-B | Method for producing protein | 花王株式会社 | 2024-03-19 | — | — | CN | disclosed |
| CN-112930195-B | Anti-human Fn14 antibodies | 安斯泰来制药株式会社 | 2024-03-19 | — | — | CN | disclosed |
| CN-117730096-A | Proteins that bind NKG2D, CD16 and EGFR | 蜻蜓疗法股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-109750052-B | Tree shrew xanthine oxidative dehydrogenase XDH/XO cDNA full-length sequence and application thereof | 中国医学科学院医学生物学研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-112533939-B | Tumor immunotherapy composition based on attenuated listeria activated antigen presenting cells, preparation method and application | 苏州若泰医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117730099-A | anti-TMPRSS 6 antibodies and uses thereof | 瑞泽恩制药公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-111433224-B | Single domain antibodies against PD-L1 and variants thereof | 南京传奇生物科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117730101-A | NECTIN 4-resistant antibodies and multispecific protein complexes comprising same | 艾佩斯瑞生物制药公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117729935-A | Recombinant chimeric bovine/human parainfluenza virus 3 expressing SARS-COV-2 spike protein and uses thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2024-03-19 | — | — | CN | disclosed |
| US-11932683-B2 | Cellular factors involved in the cytotoxicity of Staphylococcus aureus leukocidins: novel therapeutic targets | NEW YORK UNIVERSITY (US) | 2024-03-19 | — | — | US | disclosed |
| CN-112449637-B | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117730147-A | Biosynthesis of phenylpropanoids | B基因遗传学公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114058633-B | Hydrolase gene strH, protein coded by hydrolase gene strH and application of hydrolase gene strH | 南京农业大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-111094344-B | Antibody variants | 蒂洛特斯制药股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117715930-A | Antibodies to | 瑞乔生物科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117715654-A | Pharmaceutical combination comprising an anti-CD 205 antibody and an immune checkpoint inhibitor | 牛津生物疗法有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117715940-A | anti-TREM-1 antibodies | 伊诺特伦公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-111954680-B | IL2 Rbeta/common gamma chain antibodies | 新加坡科技研究局 | 2024-03-15 | — | — | CN | disclosed |
| CN-111344019-B | Monospecific and bispecific proteins that modulate immune checkpoints as cancer treatments | 圆祥生技股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-110078814-B | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117715648-A | Antigen recognizing receptor targeting uPAR and uses thereof | 纪念斯隆-凯特琳癌症中心 | 2024-03-15 | — | — | CN | disclosed |
| CN-111518208-B | anti-CD 47 antibodies and uses thereof | 启晨佰泰(北京)医药科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-110234658-B | Neisseria meningitidis compositions and methods of use thereof | 辉瑞大药厂 | 2024-03-12 | — | — | CN | disclosed |
| CN-116199766-B | Methods of screening TCRs and isolated TCRs thereof | 清华大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-117693508-A | Combination of T cell therapy and DGK inhibitors | 朱诺治疗学股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114262688-B | Method for preparing inhibitory interneurons retaining age characteristics from non-neural cell transformation | 宁波易赛腾生物科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114901259-B | Compositions comprising exosomes bearing NF-kB inhibitors and methods of use thereof | 伊利亚斯生物制品公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114805603-B | Fusion protein of CTB/LTB polypeptide and VP8 and rotavirus vaccine | 成都康华生物制品股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-11926874-B2 | Methods for identification, assessment, prevention, and treatment of cancer using PD-L1 isoforms | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-03-12 | — | — | US | disclosed |
| CN-117677287-A | Plant protection agent based on chitinase | 环球化学股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114574513-B | Multi-main corynespora CcTLS2 protein and coding gene and application thereof | 中国农业科学院蔬菜花卉研究所 | 2024-03-08 | — | — | CN | disclosed |
| CN-114085845-B | Tobacco nicotine metabolism related gene and application thereof | 云南中烟工业有限责任公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-113173993-B | Antagonistic anti-canine PD-1 antibodies | 英特维特国际股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-113917155-B | Biomarkers for diagnosis of neuromyelitis optica lineage diseases and uses thereof | 中国人民解放军总医院第一医学中心 | 2024-03-08 | — | — | CN | disclosed |
| CN-110582567-B | Genetically modified trehalase-expressing yeasts and fermentation methods using such genetically modified yeasts | 嘉吉公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-113621585-B | Taq DNA polymerase and endonuclease chimera, and preparation method and application thereof | 华南理工大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-117677394-A | Compositions of growth factors for the treatment of ocular disorders | 克拉里斯生物医疗股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-113861294-B | Antibodies to canine interleukin-4 receptor alpha | 英特维特国际股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114032228-B | Acid cellulase Cel-Bi and gene and application thereof | 武汉新华扬生物股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110291193-B | Production of desaturated fatty alcohols and desaturated fatty alcohol acetates in yeast | 丹麦科技大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-113557259-B | Biosynthesis of gamma-and delta-lactones using cytochrome P450 enzymes with subterminal hydroxylase activity | 科纳根公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-112851816-B | PD-L1 antibodies that bind canine PD-L1 | 英特维特国际股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-113754763-B | Isolated antigen binding proteins and uses thereof | 天辰生物医药(苏州)有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117677695-A | Monoclonal antibodies that specifically bind to GD2 | 拜奥卡德联合股份公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110343179-B | Antibodies that bind lymphocyte activation gene-3 (LAG-3) and uses thereof | 上海博威生物医药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114606227-B | High-precision adenine base editor and application thereof | 复旦大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-110325549-B | anti-SIRP alpha antibodies and methods of use thereof | 艾利妥 | 2024-03-08 | — | — | CN | disclosed |
| CN-117651709-A | Modified polypeptides having lysozyme activity | CJ第一制糖株式会社 | 2024-03-05 | — | — | CN | disclosed |
| CN-117651765-A | Universal re-targeting of oncolytic HSV | 詹森生物科技公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-114152754-B | ELISA kit for detecting human Dsg1 IgG antibody and application thereof | 钱华 | 2024-03-05 | — | — | CN | disclosed |
| CN-114867347-B | Storage or transport formulations of mesenchymal stem cells and methods of making and using the same | 细胞研究私人有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-111492058-B | Bacteria that constitutively produce monophosphoryl lipid a and method for producing monophosphoryl lipid a using the same | 韩国科学技术研究院 | 2024-03-05 | — | — | CN | disclosed |
| CN-117651568-A | Intracellular delivery compositions | 比昂生物制剂公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117651564-A | Treatment of cerebrovascular events and neurological disorders | 爱尔兰国立科克大学 | 2024-03-05 | — | — | CN | disclosed |
| CN-117642432-A | Synthetic proteins for inducing immune tolerance | 威斯康星校友研究基金会 | 2024-03-01 | — | — | CN | disclosed |
| CN-117642630-A | Fibrotic biomarkers for non-alcoholic fatty liver disease | 香港大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-117642190-A | Dimer-labeled precursor conjugated with a three-linker and radiotracer derived therefrom | 梅迪阿内泽有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117642176-A | PSG1 for the treatment of osteoarthritis | 爱尔兰国立科克大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-114107269-B | Modification of nitrile hydratase amino acid motif and application thereof | 江南大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-113412329-B | Phloroglucinol resistant cells, particularly yeasts | 米其林集团总公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117616042-A | Novel anti-MASP-2 antibodies | 苏州创胜医药集团有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-114222821-B | Microorganism having enhanced L-threonine-producing ability and method for producing threonine using the same | CJ第一制糖株式会社 | 2024-02-27 | — | — | CN | disclosed |
| CN-117616112-A | Improved methods and cells for increasing enzymatic activity and insect pheromone production | 富美实农业解决方案公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117615782-A | Compositions and methods comprising antibodies conjugated to covalent peptide conjugates | 纽约大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-114057855-B | Protein for causing aphid to fall off at high temperature and application thereof | 中国农业科学院深圳农业基因组研究所 | 2024-02-27 | — | — | CN | disclosed |
| CN-117615787-A | Neutralizing monoclonal antibodies against BK virus | 西奈山伊坎医学院 | 2024-02-27 | — | — | CN | disclosed |
| CN-117616050-A | Multispecific proteins that bind to NKP46, cytokine receptor, tumor antigen and CD16A | 先天制药公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-109890201-B | Insecticidal proteins | 先正达参股股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-112135630-B | Swine fever vaccine composition and preparation method thereof | 巴伊沃爱普有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117616128-A | Recombinant production of C-20 terpene alcohols | 艾瑟拜奥尼克斯公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-114409773-B | Nanobody for novel coronavirus and application thereof | 上海洛启生物医药技术有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117597150-A | Modulation of antibody dependent cellular cytotoxicity | 思进公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117589983-A | Kit for detecting foot-and-mouth disease virus antibody and/or vesicular stomatitis virus | 上海鸣捷生物科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-111423511-B | Antigen binding proteins that bind to PD-1 | 索伦托药业有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117597365-A | Multispecific FGF21 receptor agonist and application thereof | 再生元制药公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117597109-A | Single use of polymer vesicle-associated adjuvants for stimulating immune responses | ACM 生物实验室私人有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117597451-A | Enhanced HMO formation by modifying intracellular lactose import | 帝斯曼知识产权资产管理有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-113789317-B | Gene editing using campylobacter jejuni CRISPR/CAS system-derived RNA-guided engineered nucleases | 基因工具股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114634923-B | Adenosine deaminase, base editor fusion protein, base editor system and use | 尧唐(上海)生物科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117597147-A | Inhibitors of ubiquitin-specific peptidase 22 (USP 22) and uses thereof for the treatment of diseases and disorders | 西北大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-114195900-B | Anti-4-1 BB/PD-L1 bispecific antibody and application thereof | 普米斯生物技术(珠海)有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-113957085-B | Application of clematis isoprenoyl transferase PT1 gene, and overexpression Arabidopsis thaliana strain and construction method thereof | 浙江理工大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-117580477-A | Reducing viral infection | 福克斯生物有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117580861-A | Treatment of PD-L1 negative or low expression cancers with anti-ICOS antibodies | 凯玛布有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117581103-A | Method for analyzing antibodies | 株式会社岛津制作所 | 2024-02-20 | — | — | CN | disclosed |
| CN-111372606-B | Enhancement of ATP release | 先天制药公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-110753757-B | Modified guide RNAs, CRISPR-ribonucleoprotein complexes and methods of use | 威斯康星校友研究基金会 | 2024-02-20 | — | — | CN | disclosed |
| CN-112779233-B | Recombinant glufosinate dehydrogenase, genetically engineered bacterium and application thereof in preparation of L-glufosinate | 浙江工业大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-117580593-A | Anthracycline antibody conjugates | 思进公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-112592393-B | Rice premature senility control gene ES1-3 and application thereof | 浙江师范大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-113908266-B | Serially expressed foot-and-mouth disease virus VLP subunit vaccine | 嘉兴安宇生物科技有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-112996815-B | Human PD-L1 antibodies | 天境生物科技(上海)有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20240050512-A1 | REDUCTION OF VIRAL INFECTIONS | PHOXBIO LIMITED (IE) | 2024-02-15 | — | — | US | disclosed |
| US-20240052061-A1 | METHODS AND COMPOSITIONS FOR POTENTIATING ANTITUMORAL IMMUNE RESPONSES THROUGH TARGETING OF NTPDASE3 | Purinomia Biotech, Inc. | 2024-02-15 | — | — | US | disclosed |
| CN-117561449-A | Biomarkers for determining immune oncologic response | 维恩生物科学公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-114395573-B | Method for improving yield of itaconic acid produced by whole cell catalysis by utilizing aconitic acid decarboxylase | 南京工业大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-111670250-B | Variants of fungal cellulases | 生化酶股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-114073760-B | Application of RDR protein in tumor treatment | 北京大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-115315442-B | SARS-COV-2 antibody and its application | 上海济煜医药科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117561280-A | TGF-beta bearing antigen presenting polypeptide complexes and methods of use thereof | 库尔生物制药有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117561272-A | Compositions and methods for controlling insects | 先正达农作物保护股份公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117561329-A | Stem cells, methods of producing them and uses thereof | 亥姆霍兹慕尼黑中心-德国健康与环境中心 | 2024-02-13 | — | — | CN | disclosed |
| CN-112867797-B | Fructose-4-epimerase and method for producing tagatose using the same | CJ第一制糖株式会社 | 2024-02-13 | — | — | CN | disclosed |
| CN-114317483-B | Monosaccharide kinase for catalyzing and generating L-arabinose-1-phosphate and encoding gene and application thereof | 山东大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-109415418-B | Method for producing a molecule of interest by microbial fermentation comprising a gene encoding a sugar phosphotransferase system (PTS) | 代谢探索者公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114292324-B | Strain for producing alpha-lactalbumin by coexpression of molecular chaperonin and application of strain | 江南大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-112608876-B | Living cell labeling method of biotinylated Curli protein and application thereof | 江苏大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-117545768-A | Method for screening and expressing disulfide bond-bound binding polypeptides | 应用生物医学科学研究所 | 2024-02-09 | — | — | CN | disclosed |
| CN-115160415-B | BmoR protein mutant specifically responding to n-butanol and application thereof | 北京理工大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-110325545-B | Attenuated bacteria-based protein delivery | 巴塞尔大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113735945-B | Human rotavirus VP8 recombinant protein and human rotavirus vaccine using VP8 recombinant protein | 成都迈科康生物科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115181168-B | BmoR protein mutant insensitive to ethanol and specifically responsive to n-butanol | 北京理工大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-114438052-B | Nicotinamide mononucleotide adenyltransferase mutant and application thereof | 尚科生物医药（上海）有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117545764-A | Expression systems for alpha 2 alpha5 beta 2 nicotinic acetylcholine receptors and methods of use thereof | 詹森药业有限公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2024030982-A2 | DEVICE FOR DETECTION AND PROGNOSTIC ASSESSMENT OF NEURODEGENERATIVE DISORDERS | DIADEM SPA (IT) | 2024-02-08 | — | — | WO | disclosed |
| US-20240043541-A1 | METHODS FOR TREATING HEMATOLOGIC CANCERS | NOVARTIS AG (CH) | 2024-02-08 | — | — | US | disclosed |
| CN-117529493-A | Methods and compositions | 牛津大学创新有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-11892450-B2 | Evaluation, assays and treatment of pKal-mediated disorders | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-02-06 | — | — | US | disclosed |
| CN-111748544-B | Method for efficiently expressing lysostaphin | 广东溢多利生物科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-110461869-B | Design of therapeutic immunoglobulin G4 for improved bioassay and bioprocessing characteristics | 百时美施贵宝公司 | 2024-02-06 | — | — | CN | disclosed |
| US-11891424-B2 | Methods and compositions for regenerating tissues | NellOne Therapeutics, Inc. (US) | 2024-02-06 | — | — | US | disclosed |
| CN-113604561-B | Application of SF3B1 gene mutation in auxiliary diagnosis of hybrid PRL positive pituitary adenoma | 北京市神经外科研究所 | 2024-02-06 | — | — | CN | disclosed |
| CN-114457091-B | Gene Taxip affecting quality of wheat grains and application thereof | 山东农业大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-114437228-B | Double-function fusion protein composed of IL-2 and antibody subunit | 中国科学院生物物理研究所 | 2024-02-06 | — | — | CN | disclosed |
| CN-117529331-A | Klotho secretory splice variants for use in the treatment of bone disorders | 巴塞罗那自治大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-112079924-B | PD-L1 targeted binding agent and application thereof | 苏州工业园区唯可达生物科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117529332-A | Vaccine and immunoglobulin targeting African swine fever virus, preparation method and use method thereof | IGY免疫技术和生命科学公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117529494-A | Chimeric molecules comprising IL-12 agonist polypeptides | 奥美药业有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-114630903-B | Modified polypeptides of meso-diaminopimelate dehydrogenase and methods of producing L-threonine using the same | CJ第一制糖株式会社 | 2024-02-06 | — | — | CN | disclosed |
| CN-117529333-A | T cell therapy for patients previously undergoing stem cell transplantation | 细胞基因公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117500834-A | Use of sucrose, mannitol and glycine to reduce reconstitution time of high concentration lyophilized biologic drug products | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-112626042-B | Oxidoreductase as well as design, preparation method and application thereof | 厦门大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117500931-A | measles-HIV or measles-HTLV vaccine | 维洛克塞斯 | 2024-02-02 | — | — | CN | disclosed |
| CN-117500831-A | Cross-species single domain antibodies targeting PD-L1 for the treatment of solid tumors | 美国政府(由卫生和人类服务部的部长所代表) | 2024-02-02 | — | — | CN | disclosed |
| CN-115074380-B | Heading stage regulation gene Ehd5 and application thereof | 中国科学院分子植物科学卓越创新中心 | 2024-02-02 | — | — | CN | disclosed |
| CN-114716563-B | Fusion protein and preparation and application thereof | 中国科学院沈阳应用生态研究所 | 2024-02-02 | — | — | CN | disclosed |
| CN-113999857-B | Gene related to synthesis regulation of nicotine in tobacco and application thereof | 云南中烟工业有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117500823-A | Chimeric proteins in autoimmunity | 沙塔克实验室有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-110678198-B | Targeting modules to immune cells expressing universal chimeric antigen receptor and their use in the treatment of cancer, infections and autoimmune disorders | 阿文塞勒欧洲有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117500912-A | Recombinant microorganism having diamine-producing ability and process for producing diamine | 旭化成株式会社 | 2024-02-02 | — | — | CN | disclosed |
| CN-117501123-A | XX type collagen assay | 北欧生物科技公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117500927-A | Aptamer for treating coronaviridae infection | 柏林制药股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-111918876-B | anti-PD-L1 antibodies and methods of detecting PD-L1 using the same | 豪夫迈·罗氏有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117480245-A | Chimeric antigen receptor targeting oncolytic virus-derived proteins, immune cells expressing same and uses thereof | 拜耳诺克斯有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-114854708-B | Cordyceps militaris membrane protein beta-1, 3-glucan synthase and preparation method and application thereof | 江苏大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-113559239-B | Application of fusion protein in preparation of medicines for preventing and/or treating respiratory diseases | 复旦大学 | 2024-01-30 | — | — | CN | disclosed |
| US-11884979-B2 | RNA biomarkers for hereditary angioedema | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-01-30 | — | — | US | disclosed |
| CN-117479961-A | Purification method of polysaccharide and polypeptide conjugate thereof | VAXCYTE公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117480185-A | EpCAM-targeting agonistic CD28 antigen binding molecules | 豪夫迈·罗氏有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-113637661-B | Pear chitinase, coding gene thereof and application thereof in improving plant disease resistance | 南京农业大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-117480184-A | anti-DDR 2 antibodies and uses thereof | 中外制药株式会社 | 2024-01-30 | — | — | CN | disclosed |
| CN-107550748-B | Polishing paste containing staphylococcus aureus B-type enterotoxin protein and procyanidine and preparation and application thereof | 曾庆明 | 2024-01-30 | — | — | CN | disclosed |
| CN-114402105-B | Enzymatic treatment of pulp | 诺维信公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117480262-A | Biomarkers and methods for classifying subjects after viral exposure | 普尔贝格制药(英国)有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-112779238-B | DNA polymerase mixture for hepatitis C virus detection | 广州达安基因股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117460829-A | Modified alpha-isopropyl malate synthase | 绿色地球研究所株式会社 | 2024-01-26 | — | — | CN | disclosed |
| CN-117460529-A | Use of anti-ICOS antibodies | 凯玛布有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117460833-A | Oncolytic viruses expressing anti-ROR 1/anti-CD 3 bispecific antibodies | 索伦托药业有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117460744-A | Antibodies targeting AFP peptide/MHC complexes and uses thereof | 南京传奇生物科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-111465705-B | Method for removing and/or detecting nucleic acid having mismatched nucleotides | 新英格兰生物实验室公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-111065621-B | New method for preparing antibody-drug conjugate | 第一三共株式会社 | 2024-01-26 | — | — | CN | disclosed |
| CN-112687325-B | Polypeptide vaccine composition aiming at targeted drugs of alatinib, ceritinib and crizotinib and design method thereof | 杭州纽安津生物科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-110290801-B | anti-TAU antibodies and methods of use | 基因泰克公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114106144-B | TCR for identifying HLA-A 02/WT1 target and application thereof | 溧阳瑅赛生物医药有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114729338-B | Variant dihydropyridine dicarboxylic acid reductase polypeptides and methods of producing L-threonine using the same | CJ第一制糖株式会社 | 2024-01-26 | — | — | CN | disclosed |
| CN-113980939-B | Glucose-resistant beta-glucosidase, and expression gene and application thereof | 海南大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-117441008-A | Recombinant microorganism and method for producing C6 compound | 旭化成株式会社 | 2024-01-23 | — | — | CN | disclosed |
| CN-112135840-B | Single domain antibodies that bind to tetanus neurotoxin | 斯米维特公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117441024-A | Polynucleotide enzymatic synthesis using 3 '-O-amino-2' -deoxyribonucleoside triphosphate monomers | DNA斯克瑞普特公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-115976118-B | Method and carrier for biosynthesis of nocardomperidone | 武汉合生科技有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-110249043-B | Three-dimensional microenvironment structure for controlling cell behaviour, three-dimensional surface for controlling cell behaviour and method for manufacturing an array and a three-dimensional microenvironment structure | 阿莫生命科学有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-110603055-B | Antibodies that specifically bind to the N-terminal region of lysyl-tRNA synthetases exposed on cell membranes | 塞梅蒂股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112262207-B | Polypeptides comprising carbohydrate binding activity in detergent compositions and their use for reducing wrinkles in textiles or fabrics | 诺维信公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117425668-A | SARS-CoV-2 virus specific follicular helper T cell Tfh | 国立大学法人大阪大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-113874394-B | Antibodies to | 和铂抗体有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-117425670-A | Bispecific chimeric antigen receptors and genetically engineered immune cells expressing such bispecific chimeric antigen receptors | 细胞编辑有限责任公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-110300799-B | Method for producing fatty alcohols and derivatives thereof in yeast | 丹麦科技大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-117413066-A | Biological production of flavonoids and anthocyanins using a microbial host | 德比生物技术公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117413064-A | Seamless integration of engineered zinc fingers into endogenous transcription factors to take advantage of their natural function | 纽约大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-117413056-A | Modified levan sucrase for optimized production of fructooligosaccharides | 遗传工程与生物技术中心 | 2024-01-16 | — | — | CN | disclosed |
| CN-114480328-B | Taq DNA polymerase mutant | 厦门大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-114480327-B | Taq DNA polymerase mutant | 厦门大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-117412767-A | C-X-C motif chemokine receptor 6 (CXCR 6) binding molecules and methods of use thereof | 雪绒花免疫公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117412955-A | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117396518-A | Pharmaceutical composition for treating brain diseases comprising antibody specifically binding to ASM protein as active ingredient | 梨树爱博思股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396229-A | MHC class II T cell modulating polypeptides and methods of use thereof | CUE生物制药股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-116096757-B | anti-HLA-DQ 2.5 antibodies and their use in the treatment of celiac disease | 中外制药株式会社 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396500-A | Target proteins derived from viral vectors for anticancer therapy and binding molecules or fragments thereof specifically binding thereto | 拜耳诺克斯有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396757-A | Methods of tracking maintenance of immune tolerance | 库尔制药开发公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396230-A | Targeted conjugates with therapeutic agents and oligonucleotides and uses thereof | 上海联进生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396228-A | Up-conversion nanoparticle peptide conjugates | 创延生物医药科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-114774377-B | HPPD proteins, genes, vectors, cells, compositions, uses thereof and methods for increasing herbicide resistance in crops | 华中师范大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396225-A | Combination therapy for cancer | IO生物技术公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396517-A | Antibodies that specifically bind to acid sphingomyelinase proteins | 梨树爱博思股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117396509-A | Pharmaceutical composition comprising a bispecific antibody binding to B7H4 and CD3 | 健玛保 | 2024-01-12 | — | — | CN | disclosed |
| CN-110220961-B | L-arginine detection method and sensor based on polypeptide composite membrane modified electrode | 长沙理工大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-114773475-B | PD-1 binding molecules and methods of use thereof | 宏观基因有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-114891761-B | Tth DNA polymerase mutant and application thereof | 上海威高医疗技术发展有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117377682-A | Selective stimulation of T cells in solid tumors using oncolytic virus delivery of orthogonal IL-2 | 宾夕法尼亚大学董事会 | 2024-01-09 | — | — | CN | disclosed |
| CN-117377487-A | Transferrin binding antibodies and uses thereof | 领诺(上海)医药科技有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-111213059-B | Diagnostic and therapeutic methods for cancer | 豪夫迈·罗氏有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-108064283-B | Binding triggered transcription switches and methods of use thereof | 加利福尼亚大学董事会 | 2024-01-09 | — | — | CN | disclosed |
| CN-117377767-A | Immunomodulatory molecules and uses thereof | 免疫苏醒公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-110036105-B | Modified peptides | 萨西那帕斯有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-114854722-B | Off-cut beta-1, 3-glucanase of candida mongolica and mutant and application thereof | 成都普睿法药物研发有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-111182880-B | WNT compositions and process from serum-free culture conditions | 安卡萨再生疗法公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-114317730-B | Application of TTPAL as gastric cancer monitoring or prognosis judgment marker | 香港中文大学深圳研究院 | 2024-01-09 | — | — | CN | disclosed |
| CN-110300601-B | Pyrrolobenzodiazepine-antibody conjugates | ADC治疗有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-112004819-B | Vaccine composition for foot-and-mouth disease virus A | 株式会社准绳生命科学 | 2024-01-05 | — | — | CN | disclosed |
| CN-117355318-A | Gamma delta T cell co-stimulation | 沙塔克实验室有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117338917-A | Influenza vaccine | 斯微(上海)生物科技股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343198-A | Whitening peptide with repairing effect and preparation method and application thereof | 西安德诺海思医疗科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117355319-A | HER2/4-1BB bispecific fusion proteins for use in cancer treatment | 皮里斯制药有限责任公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113999863-B | Method for improving water utilization efficiency of tomato crops | 浙江大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-116083398-B | Isolated Cas13 proteins and uses thereof | 广州瑞风生物科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-111484987-B | Heat-resistant DNA polymerase mutant with high amplification activity | 广州达安基因股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117355605-A | Isopropyl malate synthase variants and methods of producing L-leucine using the same | CJ第一制糖株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-110092837-B | UTI fusion proteins | 武田有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-113604562-B | Application of SF3B1 gene mutation in auxiliary diagnosis of prolactin type pituitary adenoma | 北京市神经外科研究所 | 2024-01-02 | — | — | CN | disclosed |
| CN-117337305-A | Type 1 interferon receptor inhibitor steroid sparing in patients with systemic lupus erythematosus | 阿斯利康(瑞典)有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117337304-A | Combination of anti-PD 1 antibodies and anti-CTLA 4 antibodies | 齐鲁普吉湾生物治疗公司 | 2024-01-02 | — | — | CN | disclosed |
| US-11858917-B2 | Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus | YALE UNIVERSITY (US) | 2024-01-02 | — | — | US | disclosed |
| CN-117327176-A | anti-TSLP single domain antibody and application thereof | 南京融捷康生物科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117337301-A | Antibodies to | 瑞乔生物科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117337298-A | MHC class II T cell modulating polypeptides for treating type 1 diabetes (T1D) and methods of use thereof | CUE生物制药股份有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-112368388-B | Method for producing protease-resistant washing enzyme | 青岛蔚蓝生物集团有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117320744-A | Therapeutic combinations for the treatment of cancer | 耐考德治疗股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117321080-A | Combination therapy using anti-CD 38 antibodies and PARP or adenosine receptor inhibitors | 詹森生物科技公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-110022893-B | Immunogenic compounds for cancer therapy | 恩特罗姆公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117321417-A | Method for determining the efficacy of therapeutic cell compositions | 朱诺治疗学股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117321079-A | Bispecific epitope-binding proteins comprising anti-4-1 BB antibodies and PD-1 proteins or fragments thereof and uses thereof | 优特力克斯有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117321082-A | anti-KLRG 1 antibodies | 阿波科有限责任公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117321189-A | Single vessel expansion of lymphocytes | 泰根制药有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117305277-A | Novel glycosidase for degrading acarbose and application thereof | 中国科学院分子植物科学卓越创新中心 | 2023-12-29 | — | — | CN | disclosed |
| CN-117321077-A | Bispecific molecules and related compositions and methods | 小利兰·斯坦福大学理事会 | 2023-12-29 | — | — | CN | disclosed |
| CN-114591953-B | Construction method of CD163 gene pig-derived mouse model | 江苏集萃药康生物科技股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117321197-A | Background-dependent, double-stranded DNA-specific deaminase and uses thereof | 马奇疗法公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117295768-A | Glycospecific nanobodies and methods of use thereof | 洛克菲勒大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-117295766-A | Antibodies specific for sialic acid binding IG-like lectin 15 and uses thereof | 艾佩斯瑞生物制药公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-113943716-B | Intermolecular exo selective Diels-Alder reaction enzyme and application thereof | 北京大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-117295516-A | Vaccine compositions and methods for treating HSV | 雷德生物科技股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-110997698-B | Immunomodulatory agents acting as PD-1 antagonists | 百时美施贵宝公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117295765-A | Novel anti-CD 276 antibodies and uses thereof | 德琪(杭州)生物有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-113322288-B | Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycoside compounds and application thereof | 中国科学院分子植物科学卓越创新中心 | 2023-12-26 | — | — | CN | disclosed |
| CN-117285646-A | Fusion protein and application thereof in correction of GLA gene mutation | 四川大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-110719954-B | Therapeutic agent for glycogen storage disease type III | 奥特吉尼克斯制药公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117295823-A | Method for reconstitution of T cell selection and uses thereof | 得克萨斯大学体系董事会 | 2023-12-26 | — | — | CN | disclosed |
| CN-117279931-A | Combinations of PRAME specific T cell receptors and chimeric co-stimulatory receptors | 基因医疗免疫疗法有限责任公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117279952-A | Methods for treating cancer using subcutaneous administration of anti-PD 1 antibodies | 默沙东有限责任公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-114907458-B | Vip3A mutant protein with improved activity and application thereof | 山东大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-114302963-B | Flowering phase gene and method of use thereof | 未名生物农业集团有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-110382544-B | Compositions and methods for treating cancer | 先天制药公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117279706-A | Enhanced enzyme cleaner for membranes and cleaning method thereof | BL 科技公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-113373130-B | Cas12 protein, gene editing system containing Cas12 protein and application | 复旦大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-111542543-B | Antibodies to PD-L1 and variants thereof | 南京传奇生物科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-117279669-A | Hybrid AAV-finger loop vectors | 旗舰先锋创新V股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-20230408528-A1 | PEPTIDE QUANTITATION ASSAY FOR DIFFERENTIATING FULL-LENGTH HIGH MOLECULAR WEIGHT KININOGEN (HMWK) ANDCLEAVED HMWK | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-21 | — | — | US | disclosed |
| CN-111647074-B | HER3 dimerization interface antigen peptide, recombinant antigen peptide, encoding gene and application thereof | 皖南医学院 | 2023-12-19 | — | — | CN | disclosed |
| US-11845788-B2 | Antibody therapies for human immunodeficiency virus (HIV) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-12-19 | — | — | US | disclosed |
| CN-117255802-A | anti-CD 30L antibodies and uses thereof | 普罗米修斯生物科学公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-114786729-B | Antibody-STING agonist conjugates and their use in immunotherapy | 免疫传感器治疗股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-110062766-B | anti-LAG-3 antibodies and compositions | 正大天晴药业集团股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-111670198-B | Binding proteins for the human thrombin receptor PAR4 | 莫纳什大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-117229385-A | PD-1 variants and uses thereof | 北京卡替医疗技术有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117241841-A | anti-oxMIF radioimmunoconjugates | 翁科奥内研发有限责任公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117241787-A | Accelerated method for preparing lyophilized protein formulations | 安进公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117229409-A | Anti-phencyclidine antibody, reagent for detecting phencyclidine and kit | 东莞市朋志生物科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-110087682-B | Combination therapy with targeted 4-1BB (CD 137) agonists | 豪夫迈·罗氏有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117242096-A | Heterodimeric bispecific antibodies that bind PSMA and CD3 | 阿帕特夫研究和发展有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117241780-A | Biological delivery system | 帕帝塞拉公司 | 2023-12-15 | — | — | CN | disclosed |
| EP-3839514-B1 | IMMUNOASSAY TO DETECT CLEAVED HIGH MOLECULAR WEIGHT KININOGEN | TAKEDA PHARMACEUTICALS CO (JP) | 2023-12-13 | — | — | EP | disclosed |
| CN-114375308-B | Monoclonal antibodies against TFPI | 苏州康宁杰瑞生物科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222744-A | Method and kit for enzymatic synthesis of G4-explosive polynucleotides | DNA斯克瑞普特公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222430-A | Treatment of cutaneous lupus erythematosus | 阿斯利康(瑞典)有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222663-A | Methods of treating cancer using multi-specific binding proteins that bind NKG2D, CD16 and tumor-associated antigens | 蜻蜓疗法股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222421-A | T cell modulating polypeptides and methods of use thereof | CUE生物制药股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222672-A | anti-CLDN 4-anti-CD 137 bispecific antibodies | 安斯泰来制药株式会社 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222736-A | Cellular production of biological products | 因比奥斯公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222622-A | Polysubstituted galectin derivative and use method thereof | 恩维瑞克生物科学加拿大公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-113552269-B | Cashmere protein labeling method and peptide sequence of differential expression protein thereof | 内蒙古农业大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222671-A | ADAMTS-binding immunoglobulin administration method | 诺华股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222418-A | Methods of enhancing HLA haplotype expression diversity in tumors to expand sensitivity of tumor cells to TCR-T therapy | T-CURE生物科学公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117222664-A | Vaccine composition for disruption of self tolerance | 拜耳动物保健有限责任公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-113574072-B | Antibodies targeting C5aR | 莫佛塞斯公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117186222-A | PD-L1 binding molecules and uses thereof | 北京天广实生物技术股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117186237-A | Insulin hybrid peptide containing chymotrypsin inhibitory peptide and application thereof | 中国医学科学院药物研究所 | 2023-12-08 | — | — | CN | disclosed |
| CN-117187377-A | RNA biomarkers for hereditary angioedema | 武田药品工业株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-111886254-B | Single domain antibodies against LAG-3 and uses thereof | 南京传奇生物科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114349868-B | Novel coronavirus S protein receptor binding domain fusion protein containing oligomerization structural domain and application thereof | 中国医学科学院基础医学研究所 | 2023-12-08 | — | — | CN | disclosed |
| CN-117186224-A | anti-CD 40 antibodies | 明济生物制药（北京）有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-110036033-B | Chimeric phagocytic receptor molecules | 森罗治疗公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117202897-A | Combination therapy using RAF inhibitors and PD-1 axis inhibitors | 基因泰克公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117187279-A | Gu Weijun biosynthesis genes, gene clusters, proteins, application thereof and method for preparing Gu Weijun elements | 远大产业控股股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-110857319-B | Isolated T cell receptor, modified cell, encoding nucleic acid and application thereof | 杭州康万达医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-110087677-B | Broadly neutralizing antibodies targeting the inner fusion loop of ebola virus glycoprotein | 生物综合治疗有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117192130-A | Protein biomarkers for contact activation system related diseases | 武田药品工业株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-117202928-A | Protein-based nanoparticle vaccine for metapneumovirus | Icosavax股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117186238-A | Recombinant fusion protein targeting PD-L1 and VEGF, preparation and application thereof | 宜明昂科生物医药技术（上海）股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117203238-A | CD70 binding agents, conjugates thereof, and methods of use thereof | 普方生物制药美国公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112823025-B | Compositions and methods for treating diseases by inhibiting exosome release | 莫尔豪斯医学院 | 2023-12-08 | — | — | CN | disclosed |
| CN-117164708-A | Long-acting IL5 nanobody and application thereof | 上海洛启生物医药技术有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117178056-A | Method for producing seamless DNA vector | 南洋理工大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-110438090-B | Scale shedding disease (SDD) pathogenic virus and derivatives thereof | 英特维特国际股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-113402609-B | Canine antibodies with modified CH2-CH3 sequences | 英特维特国际股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117169508-A | Metabolite biomarkers for diseases associated with contact activation systems | 武田药品工业株式会社 | 2023-12-05 | — | — | CN | disclosed |
| CN-111372943-B | Adenovirus and use thereof | 扬森疫苗与预防公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117178189-A | Method for detecting neurofilament light chains in plasma and cerebrospinal fluid | 华盛顿大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164719-A | Bispecific antibody targeting SIRP alpha and PD-L1 or antigen binding fragment thereof and application | 启愈生物技术(上海)有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-114196642-B | Glutamate dehydrogenase variants and their use in the preparation of L-amino acids | 浙江大学杭州国际科创中心 | 2023-12-05 | — | — | CN | disclosed |
| CN-117177747-A | Targeted bifunctional degradants and methods of use thereof | 耶鲁大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-117165546-A | Method for improving fermentation yield of L-amino acid | 胡丹 | 2023-12-05 | — | — | CN | disclosed |
| CN-111295449-B | Adenovirus vector and use thereof | 扬森疫苗与预防公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117165545-A | Alpha-isopropyl malate synthase mutant, recombinant microorganism and application thereof | 胡丹 | 2023-12-05 | — | — | CN | disclosed |
| CN-111803478-B | Detection and use of low molecular weight modulators of cold menthol receptor TRPM8 | 巴斯夫欧洲公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117177994-A | Multispecific binding moieties comprising novel PD-1 binding domains | 美勒斯公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117165554-A | X chromosome linked DEAD box helicase 3 truncated protein, application and detection method | 上海交通大学医学院附属仁济医院 | 2023-12-05 | — | — | CN | disclosed |
| CN-114945598-B | Monoclonal antibody of matrix metalloproteinase 1, detection kit and detection method thereof | 世延生医股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-117157306-A | Immunomodulators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-117147851-A | Application of nerve Cong Su B2 and polypeptide fragment thereof as urine reference marker | 张曼 | 2023-12-01 | — | — | CN | disclosed |
| CN-117157386-A | Variant bacterial strains and methods for protein or biomass production | 太阳食物有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-117157326-A | anti-I INF receptor antibody anilurumab for treating lupus nephritis | 阿斯利康(瑞典)有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-117157058-A | Exosomes loaded with FAS-associated factor 1 (FAF 1) and their use as anticancer agents | 康佳诺医疗科技发展有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-117147850-A | Application of nerve guidance molecule 5A and polypeptide fragment thereof as urine reference marker | 张曼 | 2023-12-01 | — | — | CN | disclosed |
| CN-117157396-A | Cell production of sialylated di-and/or oligosaccharides | 因比奥斯公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-117157321-A | anti-TMEM 106B antibodies for the treatment and prevention of coronavirus infection | 艾莱克特有限责任公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-114621349-B | Targeting PD-L1/HSA/CCL5 trispecific nano-antibody, derivative thereof and application thereof | 青岛大学附属医院 | 2023-12-01 | — | — | CN | disclosed |
| CN-117157324-A | anti-CNTN 4 antibodies and uses thereof | 韩国亿诺生物有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-111560385-B | Axmi477, AXMI482, AXMI486, and AXMI525 toxin genes and methods of use | 巴斯夫农业解决方案种子美国有限责任公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-113880941-B | Recombinant humanized IxIII collagen, expression strain and application thereof | 江苏江山聚源生物技术有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114591939-B | High-heat-resistance D-psicose-3-epimerase mutant and application thereof | 天津科技大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-114790248-B | MUC1-PDL1-IgG1Fc tumor vaccine and preparation method and application thereof | 广州医科大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-117136009-A | Materials and methods for protein production | 非凡食品有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114805607-B | EGFRvIII-PDL1-GMCSF tumor vaccine and preparation method and application thereof | 广州医科大学 | 2023-11-28 | — | — | CN | disclosed |
| US-11826758-B2 | Evacuated blood collection tubes containing protease inhibitors for the assessment of contact system activation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-11-28 | — | — | US | disclosed |
| CN-115154419-B | Nanometer micelle precursor, nanometer micelle, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-11-28 | — | — | CN | disclosed |
| CN-114854728-B | Proline racemase and preparation and application thereof | 云南师范大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120479-A | SAP FC fusion proteins and methods of use thereof | 阿特拉斯公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120097-A | Selective drug release of internalized bioactive compound conjugates | 思进公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120622-A | Gene therapy for the treatment of beta-hemoglobinopathies | 上海科技大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-114437232-B | Cell surface macromolecule quantitative display system and preparation method and application thereof | 中国科学院分子细胞科学卓越创新中心 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120442-A | Tricyclic compounds useful for treating cancer, autoimmune disorders, and inflammatory disorders | 薛定谔公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-113683678-B | Recombinant I-type humanized collagen C1L2T and preparation method and application thereof | 山西锦波生物医药股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-112143719-B | Modified homoserine dehydrogenase and method for producing homoserine or L-amino acid derived from homoserine using the same | CJ第一制糖株式会社 | 2023-11-24 | — | — | CN | disclosed |
| CN-112481273-B | Colorectal cancer inhibiting gene and verification method for high DNA methylation of promoter region of colorectal cancer inhibiting gene | 南通大学附属医院 | 2023-11-24 | — | — | CN | disclosed |
| CN-117098849-A | Use of CD 8-targeting viral vectors | 萨那生物科技公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117098776-A | Use of anti-TGF-beta antibodies and other therapeutic agents for the treatment of proliferative diseases | 诺华股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114480322-B | Oat glycosyltransferase AsUGT73E5 and application thereof in steroid saponin synthesis | 东北林业大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-117098773-A | Antibodies specific for coronavirus spike proteins and uses thereof | 株式会社绿十字 | 2023-11-21 | — | — | CN | disclosed |
| CN-117098846-A | Norovirus-derived peptides, polynucleotides, antibodies, compositions, and methods of identifying neutralizing epitopes of norovirus | 电化株式会社 | 2023-11-21 | — | — | CN | disclosed |
| CN-115247185-B | OsAPL protein and application of encoding gene thereof in regulation and control of plant yield | 中国科学院植物研究所 | 2023-11-21 | — | — | CN | disclosed |
| CN-117089572-A | Low off-target base editor and construction thereof | 中国科学院天津工业生物技术研究所 | 2023-11-21 | — | — | CN | disclosed |
| CN-112088017-B | Freeze-dried pharmaceutical composition for naked deoxyribonucleic acid gene therapy | 赫利世弥斯株式会社 | 2023-11-21 | — | — | CN | disclosed |
| CN-110475569-B | EGFR-TKI-resistant non-small cell lung cancer therapeutic agent and application of anti-HER 3 antibody-drug conjugate | 第一三共株式会社 | 2023-11-21 | — | — | CN | disclosed |
| CN-117070477-A | Reprogrammed functional fragments of recombinant oncolytic viruses, combinations and uses thereof | 纽伦捷生物医药科技（上海）有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117083295-A | Neutralizing antibodies to IL-17A, fusion proteins thereof and uses thereof | 拉尼尔生物治疗公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117083370-A | Detergent compositions with reduced polymer content | 诺维信公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-110100003-B | Production of Minol | 弗门尼舍有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117083297-A | anti-PD-L1 monoclonal antibodies and fusion proteins with interleukin-15 (IL-15), interleukin-15 receptor 15 alpha or interleukin-2 | 艾佩斯瑞生物制药公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-114075559-B | 2-type CRISPR/Cas9 gene editing system and application thereof | 珠海舒桐医疗科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-113817711-B | Method for foam separation of beta-glucosidase fusion protein | 苏州健雄职业技术学院 | 2023-11-17 | — | — | CN | disclosed |
| CN-117083080-A | Antibody and taxane combination therapies | 健玛保 | 2023-11-17 | — | — | CN | disclosed |
| CN-113913378-B | T lymphocyte and application thereof | 深圳市菲鹏生物治疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-11815516-B2 | Protein biomarkers for diseases associated with the contact activation system | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-11-14 | — | — | US | disclosed |
| CN-117062914-A | Methods and compositions | 植物生物科学有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-117062624-A | Neutralizing monoclonal antibodies against COVID-19 | 瓦尔-查姆合伙有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-112074297-B | Antibodies that bind PD-1 and uses thereof | 深圳市亦诺微医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-117062911-A | Treatment of amyotrophic lateral sclerosis | 渤健马萨诸塞州股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-117062912-A | Fusion proteins for CRISPR-based transcriptional inhibition | 达尔马科恩有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-110582513-B | Bispecific binding molecules against TNF-related apoptosis-inducing ligand receptor 2 and anti-cadherin-17 for the treatment of cancer | 勃林格殷格翰国际有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-117050977-A | High activity cellulase mutant and composition thereof | 宜昌东阳光药业股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111057147-B | Monovalent blood brain barrier shuttle module | 豪夫迈·罗氏有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-117043330-A | Synthetic introns for targeted gene expression | 弗雷德哈钦森癌症中心 | 2023-11-10 | — | — | CN | disclosed |
| CN-117043327-A | Multiplex editing with CAS enzymes | 宏基因组学公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-117042798-A | Humanized anti-C5 antibody and factor H fusion protein and application thereof | 宾夕法尼亚大学理事会 | 2023-11-10 | — | — | CN | disclosed |
| CN-117042792-A | Compositions and methods involving tumor activating antibodies targeting PSMA and effector cell antigens | 佳努克斯治疗公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-117043185-A | Multispecific antibodies specific for ROR1 and CD3 | 努玛治疗有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-112251419-B | Method for generating new mutation in organism and application thereof | 青岛清原化合物有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-117043324-A | Therapeutic LAMA2 loading for the treatment of congenital muscular dystrophy | 庞培法布拉大学 | 2023-11-10 | — | — | CN | disclosed |
| US-20230355708-A1 | COMPOSITIONS FOR INHIBITING VIRAL ENTRY AND METHODS USING SAME | UNIV DREXEL (US) | 2023-11-09 | — | — | US | disclosed |
| CN-117015593-A | Use of enzymes for improving fragrance deposition | 诺维信公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-114621982-B | Biosynthesis method of geranyl diphosphate and application of geranyl diphosphate in preparation of cannabis compounds | 嘉兴欣贝莱生物科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-117015390-A | Ulinastat Ding Duotai for treating diseases | 代阿麦迪卡美国股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-117015399-A | Bispecific antibodies comprising anti-CD 137 binding molecules | 礼进生物医药科技（上海）有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-115052902-B | Lymphocyte-antigen presenting cell costimulatory factor and application thereof | 上海优替济生生物医药有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-117015374-A | Ionizable cationic lipids and lipid nanoparticles and methods of synthesis and use thereof | 潮汐疗法公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-114685685-B | Fusion protein for editing RNA and application thereof | 上海科技大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114621334-B | Application of potato StABI5 gene in drought resistance adjustment and method for adjusting drought resistance of potatoes based on gene | 安徽省农业科学院园艺研究所 | 2023-11-03 | — | — | CN | disclosed |
| CN-116997356-A | anti-ALPP/ALPPL 2 antibodies and antibody-drug conjugates | 思进股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116997654-A | Genes encoding chimeric receptors for anti-acetylcholine receptor autoantibodies | 第一三共株式会社 | 2023-11-03 | — | — | CN | disclosed |
| CN-116997354-A | Monoclonal antibodies against LILRB1 for diagnostic and therapeutic use | 德克萨斯大学体系董事会 | 2023-11-03 | — | — | CN | disclosed |
| CN-113683680-B | Recombinant I-type humanized collagen C1L1T and preparation method and application thereof | 山西锦波生物医药股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-115161301-B | High-specificity Taq DNA polymerase variant and application thereof | 山东大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-111148763-B | Antigen binding proteins that bind to 5T4 and 4-1BB and related compositions and methods | Aptevo研究与开发公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-109963586-B | Biological fusion proteins as anti-malarial vaccines | 维克芙奥私人有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116981448-A | Compositions comprising engineered plant-derived extracellular vesicles and their use as vaccines | 益生生物科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-110621699-B | BTLA agonist antibodies and uses thereof | 伊莱利利公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116981470-A | T cell modulating polypeptides and methods of use thereof | CUE生物制药股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116981696-A | anti-TMEM 106B antibodies and methods of use thereof | 艾莱克特有限责任公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116981775-A | Gene therapy for the treatment of neurodegenerative diseases | 爱博瑞株式会社 | 2023-10-31 | — | — | CN | disclosed |
| CN-113683679-B | Recombinant I-type humanized collagen C1L6T and preparation method and application thereof | 山西锦波生物医药股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-113788891-B | Recombinant I-type humanized collagen C1L4T and preparation method and application thereof | 山西锦波生物医药股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116981778-A | Method for producing cysteine knot protein | 住友制药株式会社 | 2023-10-31 | — | — | CN | disclosed |
| CN-116981692-A | Methods and compositions for delivering mRNA-encoded antibodies | 翻译生物公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116970289-A | Enzyme reaction water-soluble fluorescent dye based on oxygen control, preparation method and application | 中国科学院过程工程研究所 | 2023-10-31 | — | — | CN | disclosed |
| CN-109195991-B | Dual function antibodies specific for glycosylated PD-L1 and methods of use thereof | 斯特库比股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-113429469-B | Preparation method and application of silkworm antibacterial peptide BMGlvA2 recombinant protein | 中国海洋大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-116964197-A | Novel engineered and chimeric nucleases | 宏基因组学公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116964213-A | Method for producing fusion protein | 住友制药株式会社 | 2023-10-27 | — | — | CN | disclosed |
| CN-116963772-A | Monoclonal antibodies against human MAC-1 and uses thereof | 先知生物科技股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116949039-A | Imaging marking system based on CRISPR and application thereof | 西湖实验室(生命科学和生物医学浙江省实验室) | 2023-10-27 | — | — | CN | disclosed |
| CN-116964090-A | Conditional bispecific binding proteins | 武田药品工业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116964086-A | anti-SARS-CoV-2 antibodies and uses thereof | 艾佩斯瑞生物制药公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116963608-A | Method for selectively promoting animal welfare by modulating microbiota | 帝斯曼知识产权资产管理有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115058409-B | Triose phosphate isomerase as French phoenix tree pollen allergen and application thereof | 江苏省肿瘤医院 | 2023-10-27 | — | — | CN | disclosed |
| CN-116948030-A | anti-ASGR 1 monoclonal antibody and application thereof | 武汉大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-109072211-B | Antibacterial agent against salmonella | 莱桑多股份公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-111712257-B | Adenovirus carrying bispecific T cell adapter (BiTE) | 阿卡米斯生物公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-113769066-B | Composition for promoting wound healing and preparation method and application thereof | 成都英普博集生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-111094571-B | Effective preparation method of ambroxol | 国立大学法人新潟大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115011538-B | Escherichia coli for producing L-citrulline and construction method and application thereof | 江南大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-114395049-B | Modified peptide material of targeting SARS-CoV-2S protein RBD, preparation method and application thereof | 清华大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115232802-B | Beta-glucosidase mutant, engineering bacterium and application thereof | 浙江工业大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-116948038-A | Recombinant antigenic peptides and recombinant listeria for inducing tumor-specific immune responses | 苏州若泰医药科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-114195897-B | PD-L1 monoclonal antibody, heavy chain, light chain variable region, monoclonal cell strain, application and kit | 广州兆瑞医学生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-114908115-B | Application of chitosan binding domain amino acid sequence and method for preparing saccharomyces cerevisiae spore immobilized enzyme | 江南大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-116963747-A | Methods for identifying LILRB blocking antibodies | 德克萨斯大学体系董事会 | 2023-10-27 | — | — | CN | disclosed |
| CN-116964081-A | anti-CD 123 binding molecules and uses thereof | IGM生物科学股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116963785-A | Use of miRNA-485 inhibitors for treating diseases or conditions associated with aberrant NLRP3 expression | 生物欧赛加有限责任公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-110691794-B | anti-IGF-I receptor antibodies | 帝人制药株式会社 | 2023-10-27 | — | — | CN | disclosed |
| US-20230340402-A1 | CELL CULTURE SUBSTRATE AND MANUFACTURING METHOD THEREOF | AMOLIFESCIENCE CO., LTD. (KR) | 2023-10-26 | — | — | US | disclosed |
| EP-4262843-A1 | ANTIMICROBIAL PROTEIN, ANTIMICROBIAL RECOMBINANT PROTEIN WITH LYTIC PROPERTIES, EXPRESSION VECTOR, METHOD OF THEIR PREPARATION AND USE | Ustav Molekularnej Biologie SAV (SK) | 2023-10-25 | — | — | EP | disclosed |
| CN-111575252-B | Identification and application of rice fertility related gene OsLysRS | 先正达农作物保护股份公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116940239-A | Antibacterial methods and cells | 富利安食物科学有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-11795511-B2 | Methods and compositions for the prognosis and treatment of relapsed leukemia | NEW YORK UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| CN-116920114-A | Stable interferon fusion protein formulations and uses thereof | 珠海市丽珠单抗生物技术有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116940372-A | Haemophilus influenzae vaccine and methods of use | 罗切斯特综合医院 | 2023-10-24 | — | — | CN | disclosed |
| CN-116940687-A | Viral delivery of sialidases for the treatment of cancer | 巴塞尔大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-113943718-B | Glycosyltransferase and application thereof in marking, imaging and detection of Tn antigen | 北京大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116916959-A | Treatment or prevention of metastatic cancer | 牛津布鲁克斯大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-116917485-A | Recombinant microorganism expressing fucosyltransferase and method for producing 2' -fucosyllactose using the same | 株式会社三养社 | 2023-10-20 | — | — | CN | disclosed |
| CN-110573607-B | Multipotent stem cell assay | 洋蓟治疗有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113755518-B | Method for constructing recombinant yarrowia lipolytica and application thereof | 中国科学院天津工业生物技术研究所 | 2023-10-20 | — | — | CN | disclosed |
| CN-113917137-B | Liquid phase blocking ELISA antibody detection kit based on tandem expression of foot-and-mouth disease virus VLP | 嘉铭(固安)生物科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113584100-B | Application of lyase in preparation of oligomeric proanthocyanidins and method for preparing oligomeric proanthocyanidins by steam explosion combined with lyase | 威海百合生物技术股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113272439-B | Novel fructose-4-epimerase and method for producing tagatose using the same | CJ第一制糖株式会社 | 2023-10-20 | — | — | CN | disclosed |
| CN-116916956-A | FAP binding molecules and uses thereof | 博奥阿迪斯生物科技公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-115074369-B | Adeno-associated virus vector expressing full-length ABCA4 gene and application thereof | 成都金唯科生物科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-115261366-B | High-temperature-resistant cellobiose epimerase mutant, engineering bacterium and application thereof | 浙江工业大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-111542539-B | Recovery of T cell Activity by CD39/CD73 axis | 先天制药公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-109641968-B | Combinations of TIM-4 antagonists and PD-1 antagonists and methods of use thereof | 百时美施贵宝公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116917473-A | Prephenate dehydratase variants and methods of producing branched-chain amino acids using the same | CJ第一制糖株式会社 | 2023-10-20 | — | — | CN | disclosed |
| CN-110621695-B | anti-JAGGED 1 antigen binding proteins | 安进公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-114920833-B | New coronavirus RBD specific monoclonal antibody and application | 重庆医科大学 | 2023-10-17 | — | — | CN | disclosed |
| CN-114480323-B | Oat glycosyltransferase AsUGT73E1 and application thereof in steroid saponin synthesis | 东北林业大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-115043905-B | Peptide fragment composition for relatively quantitatively analyzing pig glycine guanyltransferase GATM and application thereof | 中国农业科学院北京畜牧兽医研究所 | 2023-10-13 | — | — | CN | disclosed |
| CN-115011569-B | Bose NemR-PS mutant and application thereof in preparation of (S) -citronellol | 浙江工业大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-116888148-A | Peptide markers for tracking genetically engineered cells | 荷兰商新基因治疗公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116888269-A | Enhancement of nitrile hydratase reactivity with aldehydes | 三菱化学株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-116887865-A | In vitro assembly of RNA-encapsulating finger ring viral capsids | 旗舰先锋创新V股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116887820-A | Adenovirus vectors and methods relating to the use of adenovirus vectors | 梅奥医学教育及研究基金会 | 2023-10-13 | — | — | CN | disclosed |
| CN-116888266-A | Method for producing target protein | 国立研究开发法人产业技术综合研究所 | 2023-10-13 | — | — | CN | disclosed |
| CN-116888141-A | GLXR protein variants or methods of producing threonine using same | CJ第一制糖株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-116887854-A | OMNI-103 CRISPR nuclease | 埃门多生物公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-111867630-B | Antibodies targeting CLDN18.2, bispecific antibodies, ADCs and CARs and uses thereof | 上海健信生物医药科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116888261-A | Synthetic viruses | 斯尼普生物群系有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-114807074-B | Aflatoxin hydrolase, encoding gene thereof, recombinant vector, recombinant bacterium and application | 江西省科学院生物资源研究所 | 2023-10-13 | — | — | CN | disclosed |
| US-20230322870-A1 | ACTINOBACILLUS PLEUROPNEUMONIAE VACCINES | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2023-10-12 | — | — | US | disclosed |
| CN-116868053-A | Methods for modulating host cell surface interactions with herpes viruses | 基因泰克公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-111690583-B | Shewanella expressing functional amyloid fibers and construction method and application thereof | 江苏大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-116867895-A | aroG aldolase variants and methods of producing branched-chain amino acids using the same | CJ第一制糖株式会社 | 2023-10-10 | — | — | CN | disclosed |
| CN-112725299-B | Mutant for improving Taq DNA polymerase tolerance, preparation method and application | 苏州白垩纪生物科技有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4250991-A1 | REDUCTION OF VIRAL INFECTIONS | Phoxbio Limited (IE) | 2023-10-04 | — | — | EP | disclosed |
| CN-116837035-A | Base editing natural killer cell and preparation method and application thereof | 上海贝斯昂科生物科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-109716129-B | RNA biomarkers for hereditary angioedema | 武田药品工业株式会社 | 2023-10-03 | — | — | CN | disclosed |
| US-11773142-B2 | Recombinant adenoviruses and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| CN-116836281-A | B7H3 antibody and bifunctional antibody comprising same | 英诺湖医药(杭州)有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116847872-A | Method for reducing pathogenic E.coli by intervention with a selective feed additive comprising an enzyme such as a muramidase | 帝斯曼知识产权资产管理有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-112661854-B | Bispecific antibody for resisting PD-L1 and TIGIT as well as preparation and application thereof | 安徽安科生物工程（集团）股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-110724697-B | Chimeric antigen receptor method and application of targeting GPC 3and CD19 double targets | 上海恒润达生生物科技股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-114591931-B | Clone expression of acetylxylan esterase and application of acetylxylan esterase in control of papermaking adhesives | 江南大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-116848134-A | Multispecific antibodies specific for IL-4R and IL-31 | 努玛治疗有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116848269-A | Multivalent particle compositions and methods of use | 阿奇洛伊斯生物制药公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116848410-A | TR-FRET based analysis for detecting antibodies in serological samples | 丹娜-法伯癌症研究公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113699163-B | Rice premature senility dwarf gene ESD1 and application thereof | 浙江师范大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-116848131-A | Engineered cells and uses thereof | 南京传奇生物科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116836293-A | Coronavirus vaccine compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116836294-A | Coronavirus vaccine compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-112930114-B | Amplification of TIL from cryopreserved tumor samples | 艾欧凡斯生物治疗公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113698498-B | polypeptide-Fc fusion protein and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2023-10-03 | — | — | CN | disclosed |
| CN-113583120-B | Monoclonal antibody against CK20 protein, cell strain, preparation method and application thereof | 福州迈新生物技术开发有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113683681-B | Recombinant I-type humanized collagen C1L3T and preparation method and application thereof | 山西锦波生物医药股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-109716138-B | Protein biomarkers for contact activation system related diseases | 武田药品工业株式会社 | 2023-10-03 | — | — | CN | disclosed |
| CN-116829183-A | Methods of treating cancer by administering therapeutic doses of bispecific T cell engagement molecules | 美国安进公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116829685-A | Lipase with low malodor production | 诺维信公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116829592-A | Therapeutic B7-H4 binding molecules | 免疫医疗有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-114540319-B | Alkene reductase mutant, engineering bacterium and application of alkene reductase mutant and engineering bacterium in preparation of (2R, 5R) -dihydrocarvone | 浙江工业大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-116829687-A | Genetically engineered yeast cells and methods of use thereof | 伯克利发酵科学公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-110760006-B | African swine fever immune system targeting genetic engineering vaccine | 河南省生物工程技术研究中心 | 2023-09-29 | — | — | CN | disclosed |
| CN-116829126-A | Hydrogel compositions and methods of use thereof | 小利兰·斯坦福大学托管委员会 | 2023-09-29 | — | — | CN | disclosed |
| CN-116829156-A | Treatment using tumor-infiltrating lymphocyte therapy in combination with CTLA-4 and PD-1 inhibitors | 艾欧凡斯生物治疗公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116829593-A | Dividing antibodies that bind to cancer cells and target radionuclides to said cells | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-106999587-B | Multivalent mimotopes, mimotope binding antibodies and uses thereof | 希望之城公司 | 2023-09-29 | — | — | CN | disclosed |
| US-20230301948-A1 | REDUCTION OF VIRAL INFECTIONS | PHOXBIO LIMITED (IE) | 2023-09-28 | — | — | US | disclosed |
| CN-116804188-A | Alkane monooxygenase, and coding gene and application thereof | 中国科学院微生物研究所 | 2023-09-26 | — | — | CN | disclosed |
| CN-116804178-A | Construction method of nucleoside producing engineering bacteria and method for producing nucleosides | 廊坊梅花生物技术开发有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-113710233-B | Composition, lipid particle manufacturing kit, substance delivery method and detection method | 国立大学法人信州大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-114478803-B | Construction and application of novel bispecific chimeric antigen receptor | 北京大学深圳研究生院 | 2023-09-26 | — | — | CN | disclosed |
| CN-114990132-B | Application of citrus CcLFY gene in regulation and control of shoot development | 华中农业大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-112724228-B | Keratin BD-14, its preparation method, its pharmaceutical composition and use | 中国医学科学院药物研究所 | 2023-09-26 | — | — | CN | disclosed |
| CN-112794894-B | Keratin BD-17, its preparation method, its pharmaceutical composition and use | 中国医学科学院药物研究所 | 2023-09-26 | — | — | CN | disclosed |
| CN-114685671-B | Monoclonal antibody specifically binding to Taq DNA polymerase and application thereof | 深圳华大生命科学研究院 | 2023-09-26 | — | — | CN | disclosed |
| CN-110167591-B | ADAM9 binding molecules and methods of using the same | 宏观基因有限公司 | 2023-09-26 | — | — | CN | disclosed |
| US-11766478-B2 | Methods for enhancing antigen-specific immune responses | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-09-26 | — | — | US | disclosed |
| CN-116806263-A | Method for producing 2, 4-dihydroxybutyric acid or L-threonine using microbial metabolic pathway | 德累斯顿科技大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-116801897-A | Homodimer and heterodimer proteins comprising a milk-philin protein | 沙塔克实验室有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116802307-A | African Swine Fever (ASF) virus vaccine | 威斯特有限责任公司,以梅德基因实验室名义营业 | 2023-09-22 | — | — | CN | disclosed |
| CN-112778413-B | Antibodies against varicella zoster virus | 珠海泰诺麦博制药股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116802201-A | Compositions and methods for neurological diseases | 特拉梅斯生物公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116790454-A | Construction method of nucleoside producing strain and method for producing nucleoside | 廊坊梅花生物技术开发有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-111073952-B | Method for constructing DNA library and application thereof | 浙江安诺优达生物科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116790555-A | Development of RNA-targeted Gene editing tools | 上海鲸奇生物科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116790556-A | Development of DNA-targeted gene editing tools | 中国科学院脑科学与智能技术卓越创新中心 | 2023-09-22 | — | — | CN | disclosed |
| CN-111518214-B | Bispecific antibody targeting CLDN18.2 as well as preparation method and application thereof | 上海健信生物医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114478720-B | Non-catalytic protein gene for promoting enzymolysis of lignocellulose and non-catalytic protein and application thereof | 淮阴工学院 | 2023-09-22 | — | — | CN | disclosed |
| CN-116802738-A | Selection of neoantigens for personalized cancer vaccines | 亚马逊科技公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116801895-A | Novel bifunctional multispecific antagonists capable of inhibiting more than one ligand of the TGF-beta family and uses thereof | 韩汇泉 | 2023-09-22 | — | — | CN | disclosed |
| CN-111426828-B | Duck egg yield-reduction syndrome virus antibody detection method and kit thereof | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 2023-09-22 | — | — | CN | disclosed |
| CN-114717213-B | N-terminal truncated mutant enzyme of dextran sucrase and preparation method thereof | 广西科学院 | 2023-09-22 | — | — | CN | disclosed |
| CN-116789777-A | Application of JAZ protein and its derivative in prevention and control of agricultural pests | 中国农业科学院棉花研究所 | 2023-09-22 | — | — | CN | disclosed |
| CN-112041348-B | anti-CD 73 anti-PD-L1 bispecific antibodies | 天境生物科技(上海)有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-111050795-B | Vaccine compositions based on synthetic polypeptide epitopes | 巴拉特生物技术国际有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116790636-A | Messenger nucleic acid molecule for encoding and expressing newcastle disease virus antigen | 苏州慧疗生物医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-111315866-B | Heterologous expression of carbohydrate binding modules and use thereof for cadaverine production | 上海凯赛生物技术股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114341180-B | Humanized antibodies against PD-L1 | 上海药明生物技术有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116789820-A | Development and application of novel immunomodulator | 北京天诺健成医药科技有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20230295220-A1 | C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2023-09-21 | — | — | US | disclosed |
| US-20230295277-A1 | UNIVERSAL CAR-NK CELL TARGETING VARIOUS EPITOPES OF HIV-1 GP160 | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2023-09-21 | — | — | US | disclosed |
| CN-111032862-B | Novel O-succinylhomoserine transferase mutant and method for producing O-succinylhomoserine using the same | CJ第一制糖株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-110770340-B | Optimization of serine protease expression in host cells | BRAIN生物科技股份公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116782937-A | anti-PD-1 antibodies and uses thereof | 优特力克斯有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116783281-A | Methods and compositions for preparing amide compounds | 基因组股份公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-109563171-B | Binding molecules that bind PD-L1 and LAG-3 | F-星治疗有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116782768-A | Control of nocturnal moth, meadow moth and borer moth pests | 先正达生物科技（中国）有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-108697779-B | Cancer vaccine and delivery method | 杜克大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-114934029-B | Taq DNA polymerase variant, its obtaining method and application in genome editing | 山东大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-116783284-A | Compositions, constructs and vectors for cell reprogramming | 阿斯加德治疗有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116782896-A | Nitrifying galectin derivatives and their use for modulating 5-HT2A receptors and treating psychotic disorders | 恩维瑞克生物科学加拿大公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116783219-A | T cell recruitment polypeptides based on TCR alpha/beta reactivity | 埃博灵克斯股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116782928-A | Lentiviral vectors capable of delivering antigen to the MHC-II pathway and inducing CD4+ and CD8+ T cell responses in a host | 赛拉福柯蒂斯公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113912685-B | Protein for regulating and controlling dark respiration of plant leaves and application thereof | 中国科学院分子植物科学卓越创新中心 | 2023-09-15 | — | — | CN | disclosed |
| CN-116761887-A | Bispecific antibodies targeting sirpa and PD-L1 | 上海礼新医药研发有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116761825-A | Multi-specific binding protein degradation agent platform and method of use | 基因泰克公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-114853901-B | Construction and application of engineering bacteria for expressing antibacterial peptide AFP1 fusion protein | 四川贝斯安贸易有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-113684197-B | Peanut chitinase and application thereof | 山东省花生研究所 | 2023-09-15 | — | — | CN | disclosed |
| CN-116762009-A | Method and kit for detecting presence and/or amount of enterobacteriaceae bacteria in food or beverage samples, environmental samples or biological samples | 旭化成株式会社 | 2023-09-15 | — | — | CN | disclosed |
| CN-116744976-A | HER3 Radioimmunotherapy for the Treatment of Solid Cancers | 锕医药有限责任公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745413-A | Composition for preparing fructose and preparation method | 庆尚国立大学校产学协力团 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745415-A | Engineered CRISPR-CAS proteins and methods of use thereof | 成对植物服务股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745430-A | Production of oligosaccharides comprising LN3 as core structure in host cells | 因比奥斯公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-110128509-B | Phage display foot-and-mouth disease particle, preparation method and vaccine | 石河子大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745410-A | Genetically engineered bacteria capable of producing cytokinins with isoprenoid side chains | 阿西耶斯生物公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-112673023-B | anti-SIRP alpha antibodies | 国立大学法人神户大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116732068-A | Gene for encoding chimeric antigen receptor, vector, modified cell and application thereof | 创新细胞治疗控股有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-113717915-B | Xanthomonas oryzae with ACC deaminase expressed on surface as well as construction method and application thereof | 中国科学院微生物研究所 | 2023-09-12 | — | — | CN | disclosed |
| CN-113801884-B | NtJAZ1 gene mutant for improving nicotine content of tobacco leaves and application thereof | 云南省烟草农业科学研究院 | 2023-09-12 | — | — | CN | disclosed |
| CN-111065727-B | Cell culture vessel | 阿莫生命科学有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745423-A | Heterologous peptide production based on fluorescent fusion | 斯坦陵布什大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-114058560-B | Process for the production of glycine | 中国科学院天津工业生物技术研究所 | 2023-09-12 | — | — | CN | disclosed |
| CN-116744981-A | combination therapy | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745313-A | Reprogramming immune cells by targeted integration of zeta-deficient chimeric antigen receptor transgenes | 柏林夏瑞蒂医科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745418-A | Compositions and methods for RNA-encoded DNA replacement of alleles | 成对植物服务股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-113382634-B | Engineered pesticidal proteins and methods of controlling plant pests | 先正达农作物保护股份公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-111315213-B | anti-transthyretin antibodies | 普罗塞纳生物科学有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-110423282-B | Chimeric antigen receptor and methods of use thereof | 加利福尼亚大学董事会 | 2023-09-08 | — | — | CN | disclosed |
| CN-114685663-B | Antibody for resisting cholesterol-dependent cytolysin and application thereof | 西南大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-116723852-A | Method for treating diabetes | 伊莱利利公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116724047-A | Anti-tumor response against cytokeratin | 斯坎塞尔有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-115746132-B | anti-IL-17A antibodies and uses thereof | 三优生物医药(上海)有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116723866-A | anti-PD-L1 immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116724049-A | Neutralizing antibodies against SARS-associated coronavirus | 科隆大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-114264828-B | Biomarker for identifying benign thyroid nodule and thyroid cancer and application thereof | 中国科学院基础医学与肿瘤研究所(筹) | 2023-09-08 | — | — | CN | disclosed |
| CN-114277045-B | Construction and application of amide compound biosensor | 江南大学 | 2023-09-08 | — | — | CN | disclosed |
| US-20230276828-A1 | ANIMAL FEED COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2023-09-07 | — | — | US | disclosed |
| CN-116710477-A | Protein matrix binding growth factors | 肿瘤微环境治疗有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116710552-A | Liver cell cancer treatment and preventive therapy and composition used for same | 修理生物科技公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113717910-B | Tri-enzyme co-expression recombinant bacterium and application thereof in (S) -citronellol synthesis | 浙江工业大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-116710080-A | Compounds for treatment of hemophilia | 格勒诺布尔大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-116710562-A | CYP81E gene conferring herbicide tolerance | 科罗拉多州立大学研究基金会 | 2023-09-05 | — | — | CN | disclosed |
| CN-116710143-A | Compounds for preventing or treating myasthenia gravis | 艾柏力维亚生技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-111961137-B | Fusion protein with bionic endothelial cell function and application thereof | 南开大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-116693630-A | African swine fever virus p34-p14 subunit protein, application and product thereof | 普莱柯生物工程股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116710120-A | Recombinant ACE2-FC fusion molecules and methods of making and using the same | 四川百利药业有限责任公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116710119-A | Method for treating diabetes | 伊莱利利公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116709908-A | Method for controlling grain size | 中国科学院遗传与发育生物学研究所 | 2023-09-05 | — | — | CN | disclosed |
| CN-108472347-B | Methods for treating conditions associated with MASP-2 dependent complement activation | 奥默罗斯公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116710132-A | Dosing regimen of anti-ILT 4 antibodies or combinations thereof with anti-PD-1 antibodies for the treatment of cancer | 默沙东有限责任公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-111699198-B | Single domain antibodies to TIGIT and variants thereof | 南京传奇生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116688125-A | Application of SEMA3G antibody in preparation of anti-tumor or immunity-regulating medicines | 复旦大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-116685204-A | Modulating antimicrobial peptide half-life | 辛格隆股份公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116685603-A | B and T lymphocyte attenuation factor (BTLA) modulators and methods of use thereof | 安奈普泰斯生物有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114874330-B | Neutralizing monoclonal antibodies targeting single chain antibodies | 南京驯鹿生物技术股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-112142842-B | anti-PD-L1 nano antibody, fc fusion protein thereof and application | 启愈生物技术(上海)有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116685325-A | Combination therapy of a PD-1 axis binding antagonist and an LRRK2 inhibitor | 豪夫迈·罗氏有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116685340-A | Low dose hepatocyte growth factor gene therapy for diabetes | 国立大学法人鹿儿岛大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-116685597-A | WW domain activated extracellular vesicles | 哈佛大学的校长及成员们 | 2023-09-01 | — | — | CN | disclosed |
| CN-114164129-B | Recombinant pichia pastoris for heterologously expressing myrosinase and application of recombinant pichia pastoris in preparation of sulforaphane | 江南大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-116670271-A | Novel OMNI-50CRISPR nuclease-RNA complex | 埃门多生物公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116670286-A | Human anti-TIGIT monoclonal antibodies for immune related diseases | 华辉安健（北京）生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114605536-B | Affinity purification method for reducing host cell protein content in production of anti-human thymus stroma lymphopoietin monoclonal antibody | 江苏荃信生物医药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115161302-B | High-specificity Taq DNA polymerase variant and obtaining method and application thereof | 山东大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-116656641-A | Caffeic acid O-methyltransferase mutant and application thereof | 中国科学院分子植物科学卓越创新中心 | 2023-08-29 | — | — | CN | disclosed |
| CN-114057878-B | Affinity purification method for reducing host cell protein content in monoclonal antibody production | 江苏荃信生物医药股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-113583122-B | Anti-human SEMA4D antibody and preparation method and application thereof | 武汉华美生物工程有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-111057729-B | (R) -2- (2, 5-difluorophenyl) pyrrolidine and preparation method and application thereof | 弈柯莱生物科技(上海)股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110381998-B | anti-LAIR 1 antibodies and uses thereof | 德克萨斯大学体系董事会 | 2023-08-29 | — | — | CN | disclosed |
| CN-113260368-B | Combination of anti-GPC 3 Chimeric Antigen Receptor (CAR) and trans-costimulatory molecules and therapeutic uses thereof | 舒迪安生物技术公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116670295-A | Amycolatopsis strain for producing vanillin with suppressed formation of vanillic acid | 巴斯夫欧洲公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116669557-A | Control of microorganisms in a microbial community | 辛格隆股份公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116669771-A | Compounds for sequestering unwanted anti-PEG antibodies in a patient | 艾柏力维亚生技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-113773972-B | Hexavalent chromium reduction strain, method and application thereof | 天津科技大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-114392345-B | Application and method of E199L protein in promoting apoptosis | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 2023-08-25 | — | — | CN | disclosed |
| CN-114107255-B | Panax japonicus saponin glycoside hydrolase and application thereof in production of ginger-like notoginsenoside R1 | 上海中医药大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116648463-A | CD47-CD38 bispecific antibodies | 伊克诺斯科学公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114958800-B | Taq DNA polymerase mutant capable of tolerating blood or blood product inhibition and application thereof | 北京脉道生物药品制造有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-110964109-B | anti-PD-L1 antibodies | 中美冠科生物技术（太仓）有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-113999831-B | GH11 family xylanase gene, clone expression thereof and ramie degumming application | 华中科技大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-113929787-B | Strategy for regulating and controlling biofilm to improve shikimic acid production performance | 江南大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116648623-A | Method for predicting and/or diagnosing a cortical condition of the scalp | 欧莱雅 | 2023-08-25 | — | — | CN | disclosed |
| CN-114277009-B | GTFB mutant and application thereof in preparing a series of isomaltose with different hydrolysis resistance | 江南大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-113527470-B | anti-pre-S1 HBV antibodies | 华辉安健（北京）生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-116648242-A | Reducing viral infection | 福克斯生物有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-113481177-B | Starch branching enzyme mutant with enhanced extracellular secretion capacity | 江南大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116635407-A | Nucleic acids encoding anchor modified antibodies and uses thereof | 瑞泽恩制药公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116617390-A | Use of ASGR1 inhibitors for promoting cholesterol efflux and for treating non-alcoholic fatty liver disease | 武汉大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-114381446-B | Heat-resistant acid-resistant arabinosidase gene, and expression protein, recombinant vector, recombinant bacterium and application thereof | 淮阴工学院 | 2023-08-22 | — | — | CN | disclosed |
| CN-116635401-A | Genetically modified methylobacterium with improved performance | 阿西耶斯生物公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116635087-A | Vaccine composition | 维罗治疗有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-109641959-B | Multispecific antibodies to CD40 and CD137 | 健玛保 | 2023-08-22 | — | — | CN | disclosed |
| CN-116635067-A | Extracellular vesicles targeting activation of the WW domain of coronaviruses | 哈佛大学的校长及成员们 | 2023-08-22 | — | — | CN | disclosed |
| CN-114507608-B | Recombinant filamentous fungus for producing ethanol in online granule body and construction and application thereof | 中国科学院天津工业生物技术研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-113476599-B | Vaccine immunopotentiator recombinant IFN gamma, IL-1 beta and TNF alpha, and preparation method and application thereof | 山东省淡水渔业研究院（山东省淡水渔业监测中心） | 2023-08-22 | — | — | CN | disclosed |
| CN-114807178-B | African swine fever virus P72 protein C-terminal multi-epitope recombinant antigen and application thereof | 广东省农业科学院动物卫生研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-113061192-B | PDL1 fusion protein with high affinity to PD-1 receptor and application thereof as T cell inhibitor | 佰思巢(上海)生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114958799-B | Taq DNA polymerase variant and application thereof in genome editing | 山东大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615208-A | Engineered cell adhesion molecules and methods of use thereof | 加利福尼亚大学董事会 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615554-A | Preparation of oxygen-containing diterpene compounds | 哥本哈根大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-110004180-B | Gene vector modified by functional peptide A25 and preparation method and application thereof | 上海海洋大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-112522175-B | Recombinant strain for producing L-glutamic acid by modifying gene BBD29_09525 as well as construction method and application thereof | 内蒙古伊品生物科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-112552412-B | A trifunctional fusion protein comprising TGF-beta inhibitor, VEGF inhibitor and anti-PDL 1 antibody | 启愈生物技术(上海)有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615439-A | Coli composition and method thereof | 辉瑞大药厂 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615458-A | Formulations of anti-CD 73 antibodies | 天境生物科技(上海)有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116606357-A | Application of GmTIFY10e protein and encoding gene thereof in regulation and control of salt tolerance of plants | 中国农业科学院作物科学研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615555-A | Enzymatic monocyclization of acyclic monoterpenes | 斯图加特大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615660-A | Chimeric anti-human BRAF V600E antibodies and methods of making and using the same | 安捷伦科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615459-A | anti-CD 94 antibodies and methods of use thereof | 德伦生物公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615227-A | Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof | 费尔丹生物公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-112687353-B | Polypeptide vaccine combination aiming at tyrosine kinase inhibitor of targeted drug EGFR (epidermal growth factor receptor) pathway and design method thereof | 杭州纽安津生物科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615256-A | Glycoconjugates | 乔治亚大学研究基金会 | 2023-08-18 | — | — | CN | disclosed |
| CN-111848793-B | Single domain antibodies against intracellular antigens | 辛格生物技术有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-114934030-B | High-specificity Taq DNA polymerase variant and application thereof in genome editing and/or gene mutation detection | 山东大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615214-A | Recombinant vaccinia virus | 公益财团法人东京都医学综合研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615523-A | Use of lipoxygenase | 诺维信公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-111053775-B | Physiologically cool active ingredient and use of substances containing such active ingredient | 西姆莱斯股份公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116615216-A | Compositions and methods for identifying and treating microparticle-related diseases and disorders | 生物保护医疗公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116601169-A | Broadly neutralizing binding molecules against marburg virus | 生物综合治疗有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-114634965-B | High-throughput screening method of malonate transporter mutant library and application of mutants and 3-hydroxypropionic acid synthesis | 青岛农业大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-112941094-B | Active mutant enzyme and method for producing soluble mutant protein | 公立大学法人 富山县立大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-115141787-B | Submarine microbial sensor and preparation method and application thereof | 青岛农业大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-116601293-A | Engineered Cas effector proteins and methods of use thereof | 中国科学院动物研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-111565747-B | Antigen fused to porcine FC fragment and vaccine composition comprising the same | 巴伊沃爱普有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-110577958-B | Nucleic acid, recombinant plasmid, transformant, acetylcholinesterase and preparation method thereof | 吾幫土智慧生活有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-113817763-B | Directed evolution method, mutant and application of beta-galactosidase family genes | 中国水产科学研究院黄海水产研究所 | 2023-08-15 | — | — | CN | disclosed |
| CN-113699131-B | Alpha-cyclodextrin glucosyltransferase mutant and application thereof | 江苏省奥谷生物科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-108048317-B | Continuous synthesis system and continuous synthesis method of unnatural amino acid | 凯莱英医药集团（天津）股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116601171-A | Combination therapy for cancer | 百时美施贵宝公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111556898-B | Recombinant vector comprising porcine FC fragment and method for preparing recombinant protein by using same | 巴伊沃爱普有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116601164-A | HIV-targeting WW domain activated extracellular vesicles | 哈佛大学的校长及成员们 | 2023-08-15 | — | — | CN | disclosed |
| CN-116583296-A | Universal influenza vaccine using nucleoside modified MRNA | 宾夕法尼亚大学理事会 | 2023-08-11 | — | — | CN | disclosed |
| CN-116583600-A | Antibodies that specifically bind to the 5 '. Fwdarw.3' exonuclease active domain of a DNA polymerase | 东洋纺株式会社 | 2023-08-11 | — | — | CN | disclosed |
| CN-109652423-B | Rice flowering phase regulating protein and application thereof in breeding | 沈阳农业大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-116583597-A | Immune checkpoint regulated VSV-NDV hybrid virus for oncolytic virus immunotherapy of cancer | 慕尼黑工业大学附属伊萨右岸医院 | 2023-08-11 | — | — | CN | disclosed |
| CN-116583504-A | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-116583605-A | Process for producing L-amino acid | 味之素株式会社 | 2023-08-11 | — | — | CN | disclosed |
| CN-108367066-B | Avian influenza vaccine compositions comprising viroids and novel adjuvants | 台湾地区“中央研究院” | 2023-08-11 | — | — | CN | disclosed |
| CN-112424225-B | anti-PD-L1 antibodies and uses thereof | 桂林三金药业股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| WO-2023148016-A1 | BIOMARKER FOR PLASMA KALLIKREIN INHIBITOR THERAPY RESPONSE | Oxurion NV (BE) | 2023-08-10 | — | — | WO | disclosed |
| CN-115181167-B | Screening method of ethanol production strain based on BmoR mutant | 北京理工大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-110337448-B | Immunotherapy using antibodies that bind to programmed death ligand 1 (PD-L1) | 瑞美德生物医药科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116554343-A | Long-acting recombinant human growth hormone and application thereof | 领诺(上海)医药科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116554324-A | Antibody capable of specifically recognizing 4-1BB, preparation method and application thereof | 三优生物医药(上海)有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116568307-A | LAG-3 antagonist therapy for lung cancer | 百时美施贵宝公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-111406104-B | Reduction of accumulation of imine/enamine for production of amino acid or amino acid derivative products | 上海凯赛生物技术股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-111315877-B | Novel O-succinylhomoserine transferase variants and methods of producing O-succinylhomoserine using the same | CJ第一制糖株式会社 | 2023-08-08 | — | — | CN | disclosed |
| CN-113512544-B | Mannose isomerase mutant with improved heat stability | 江南大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116568333-A | Use of miRNA-485 inhibitors for inducing hair growth | 生物欧赛加有限责任公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-116568806-A | Engineered guide RNAs for increasing efficiency of CRISPR/CAS12F1 (CAS 14 A1) systems and uses thereof | 基恩科雷有限责任公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-114277022-B | Nitrile hydratase mutant with high activity and high thermal stability | 江南大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116547263-A | Methods and cells for producing substituted cannabinoids and precursors using modified enzymes | 海牙森生物公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-113186175-B | Mutant Taq DNA polymerase, coding DNA sequence, recombinant vector, recombinant expression cell and application thereof | 翌圣生物科技(上海)股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-113666996-B | Tachypleus tridentatus antibacterial peptide and preparation method and application thereof | 华中农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-111072772-B | Peptide tag and application thereof in detection or purification of fusion protein | 上海良润生物医药科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-111902157-B | Composition for promoting local muscle growth, slowing down or preventing local muscle atrophy and application thereof | 松阳生技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116536353-A | Replication type efficient guide editing system | 华中农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-114805599-B | VLPs based on ADDOmer chimeric porcine O-type foot-and-mouth disease virus epitope and application | 华南农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-116536352-A | Efficient and accurate polygene editing system mediated by replication type guiding editor | 华中农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-114934033-B | Agarase mutant and encoding gene and application thereof | 青岛海洋生物医药研究院股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116547299-A | Prevention of neuronal axonal injury using antibodies that bind to amyloid beta 1-42 peptide | 米迪缪尼有限公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2023144030-A1 | PLASMA KALLIKREIN INHIBITOR THERAPY FOR ANTI-VEGF SENSITIZATION | Oxurion NV (BE) | 2023-08-03 | — | — | WO | disclosed |
| CN-116529257-A | Orthogonal IL-21 receptor/cytokine systems | 尼普图恩生物科学有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-112079928-B | anti-PD-L1 monoclonal antibody | 北京华大蛋白质研发中心有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116529256-A | Recombinant expression vector for producing capsule-based vaccine and preparation method thereof | 人太罗有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-109789191-B | Compositions and methods for inhibiting biofilm deposition and production | 宾夕法尼亚州立大学托管会 | 2023-08-01 | — | — | CN | disclosed |
| CN-110494448-B | Pharmaceutical combinations comprising anti-LY 75 antibodies | 柏林化学股份公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-114657192-B | EBNA1 truncated mRNA related vaccine and preparation method and application thereof | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2023-08-01 | — | — | CN | disclosed |
| CN-116510005-A | Combined medicine for treating tumor | 正大天晴药业集团股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116529267-A | ABCG2 efflux pump-cancer antigen multispecific antibodies and related compositions, reagents, kits and methods | 肯乔克蒂生物技术股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-109451741-B | anti-TIM-3 antibodies and compositions | 法国施维雅药厂 | 2023-07-28 | — | — | CN | disclosed |
| CN-112592905-B | DNA polymerase mixture for novel coronavirus detection | 广州达安基因股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-113817694-B | Glufosinate dehydrogenase mutant, coding gene, genetically engineered bacterium and application thereof | 浙江工业大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-116507638-A | Antigen binding proteins | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116507728-A | Leghemoglobin in soybeans | 先锋国际良种公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-107847591-B | Multivalent human immunodeficiency virus antigen binding molecules and uses thereof | IGM生物科学股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116496405-A | PD-L1 and CD47 targeted bifunctional fusion protein and application thereof | 泽达生物医药有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116507629-A | RNA scaffold | 地平线探索有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-113667010-B | Antibody against coronavirus and use of derivative thereof | 普米斯生物技术(珠海)有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-110139659-B | Peptides for the treatment of sjogren's syndrome | 耶达研究及发展有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-114107344-B | Insect-resistant fusion gene M2CryAb-VIP3A, expression vector, product and application thereof | 山东省农业科学院 | 2023-07-28 | — | — | CN | disclosed |
| CN-110869389-B | anti-ROR 1 antibodies and methods of making and using the same | 西雅图免疫公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-3831839-B1 | C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2023-07-26 | — | — | EP | disclosed |
| CN-112661843-B | Aldriterone recombinant rabbit monoclonal antibody and application thereof | 郑州伊美诺生物技术有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-114540323-B | GtfB enzyme with 4, 3/6-alpha-glucosyltransferase activity | 江南大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113862165-B | Method for directly producing low-molecular-weight xanthan gum by co-culture fermentation | 江南大学 | 2023-07-25 | — | — | CN | disclosed |
| US-11708412-B2 | Methods for treating hematologic cancers | NOVARTIS AG (CH) | 2023-07-25 | — | — | US | disclosed |
| CN-116479095-A | Ago protein/PIWI domain-containing protein-based nucleic acid polymerase reaction method and application | 杭州微编生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-112301018-B | Novel Cas protein, crispr-Cas system and use thereof in the field of gene editing | 深圳华大生命科学研究院 | 2023-07-25 | — | — | CN | disclosed |
| CN-116490521-A | Superantigen conjugates in methods and compositions for treating cancer | 尼奥克斯医疗有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-114350583-B | Method for producing 1, 2-butanediol by fermentation, recombinant microorganism and application thereof | 清华大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-109716137-B | Metabolite biomarkers for diseases associated with contact activation systems | 武田药品工业株式会社 | 2023-07-21 | — | — | CN | disclosed |
| CN-110914416-B | Microorganism and method for producing cannabinoids and cannabinoid derivatives | 加州大学董事会 | 2023-07-21 | — | — | CN | disclosed |
| CN-116472347-A | Recombinant host cell for production of anthranilic acid | 皮利公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116472059-A | Use of IL-18 antagonists for the treatment and/or prophylaxis of atopic dermatitis or related conditions | 诺华股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-110392692-B | Immunoconjugates of anti-PD-1 antibodies with mutant IL-2 or with IL-15 | 豪夫迈·罗氏有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114716541-B | Fully human broad spectrum neutralizing antibody 76E1 against coronavirus and application thereof | 中国科学院分子细胞科学卓越创新中心 | 2023-07-21 | — | — | CN | disclosed |
| CN-115011616-B | Acetaldehyde dehydrogenase gene RKALDH and application thereof | 昆明理工大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-112795555-B | High specific activity cellulase mutant and application thereof | 青岛蔚蓝生物集团有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-111105843-B | HLAI type molecule and polypeptide affinity prediction method | 杭州纽安津生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116472291-A | Multimerized CD45 binding molecules | UCB生物制药有限责任公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116463230-A | Construction method of saccharomyces cerevisiae for producing squalene | 万华化学集团股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023136608-A1 | CELL CULTURE SCAFFOLD, AND PREPARATION METHOD THEREOF | 주식회사 아모라이프사이언스 | 2023-07-20 | — | — | WO | disclosed |
| US-20230227694-A1 | ANTI-VIRAL COATING COMPOSITION, AND METHOD FOR FIXING ANTI-VIRAL FUSION PROTEIN TO SURFACES | AMOLIFESCIENCE CO., LTD. (KR) | 2023-07-20 | — | — | US | disclosed |
| EP-4210737-A1 | METHODS AND COMPOSITIONS FOR POTENTIATING ANTITUMORAL IMMUNE RESPONSES THROUGH TARGETING OF NTPDASE3 | Purinomia Biotech, Inc. (US) | 2023-07-19 | — | — | EP | disclosed |
| CN-114591978-B | Application of OsFLR14 gene in improving weed resistance of rice | 湖南大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-109777778-B | Genetically modified gamma delta T cells | 中国科学院广州生物医药与健康研究院 | 2023-07-18 | — | — | CN | disclosed |
| CN-113717960-B | Novel Cas9 protein, CRISPR-Cas9 genome directed editing vector and genome editing method | 电子科技大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-114163534-B | Bispecific chimeric antigen receptor targeting HIV-1 virus envelope protein and preparation method and application thereof | 复旦大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-114958934-B | Method for preparing L-glufosinate | 苏州百福安酶技术有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114807162-B | Method for improving photosynthetic efficiency and yield of rice | 武汉大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-110573524-B | Antibodies to PD-L1 | 健玛保 | 2023-07-18 | — | — | CN | disclosed |
| CN-116457372-A | Combination therapy | 努玛治疗有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-113817704-B | Cyclodextrin glucosyltransferase with improved organic solvent tolerance and preparation method thereof | 江南大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-113423736-B | Antibodies specific for MUC18 | 普众发现医药科技(上海)有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-116456841-A | Use of fructosyltransferase | 依纽洛克斯有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114686500-B | 1, 4-alpha-glucan branching enzyme, coding gene, engineering strain and application | 华东师范大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-116438302-A | System and method for indexing nucleotide sequences of cargo | 宏基因组学公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116437953-A | Methods and compositions for treating vascular leakage | 耶鲁大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-113481175-B | Active and stereoselectivity improved olefinic bond reductase mutant and encoding gene and application thereof | 华东理工大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-116438307-A | Aptamer against SARS-CoV-2 | 适体诊断有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-113564146-B | Heat-resistant beta-galactosidase and application thereof in lactose degradation | 青岛大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-112566933-B | anti-CD 40 antibodies and uses thereof | 祐和医药科技(北京)有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114107258-B | Thermophilic mannanase ManBK mutant and application thereof | 河北农业大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-111793613-B | Low-temperature cellulase mutant and application thereof | 青岛蔚蓝生物集团有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114539403-B | Rabbit recombinant monoclonal antibody targeting human BCMA protein and application thereof | 缔码生物科技(武汉)有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-109952380-B | Method for producing target substance | 味之素株式会社 | 2023-07-14 | — | — | CN | disclosed |
| CN-116426540-A | Af-ABC gene of aspergillus fumigatus ABC transport protein and application thereof | 荆州市中心医院(长江大学附属荆州医院) | 2023-07-14 | — | — | CN | disclosed |
| CN-114369583-B | Immobilized enzyme and application thereof in continuous production | 凯莱英生命科学技术(天津)有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116419673-A | Expression of IPT7 from TSS promoter to increase root mass and carbon sequestration | 索尔克生物研究所 | 2023-07-11 | — | — | CN | disclosed |
| CN-114410640-B | Aptamer for detecting measles virus, kit and application | 世通兰达(深圳)生物科技发展有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116410328-A | Recombinant canine PD-L1 fusion protein and preparation method and application thereof | 北京伟杰信生物科技有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116410940-A | Asymmetric reduction method for potential chiral carbon-carbon double bond by using alkene reductase and mutant thereof | 上海合全药业股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-113174378-B | Glutamate dehydrogenase mutant, encoding gene thereof, genetically engineered bacterium and application thereof in preparation of L-2-aminobutyric acid | 华东理工大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-115011619-B | Cassava MeGLYI-13 gene and application of encoding protein thereof in regulating and controlling stress resistance of eukaryotes | 中国热带农业科学院热带生物技术研究所 | 2023-07-07 | — | — | CN | disclosed |
| CN-116396381-A | Preparation and application of human adeno-associated virus (AAV) single domain antibody | 成都思柏沃生物技术有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-109182361-B | Cellulose endoenzyme gene, protein and application thereof | 怀化学院 | 2023-07-07 | — | — | CN | disclosed |
| CN-110964108-B | anti-PD-L1 antibodies | 中美冠科生物技术（太仓）有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-108882691-B | Rice grain with thickened aleurone layer | 联邦科学技术研究组织 | 2023-07-07 | — | — | CN | disclosed |
| CN-114921443-B | Application of streptococcus pneumoniae endopeptidase O in preparation of antitumor drugs | 重庆医科大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-116406420-A | Genetically modified microorganisms for producing 3-hydroxy adipic acid and/or alpha-hydrogenated hexadienoic acid and method for producing the same | 东丽株式会社 | 2023-07-07 | — | — | CN | disclosed |
| CN-116406377-A | anti-NOTCH 2 antibodies and methods of use thereof | 基因泰克公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-114369588-B | Neutral cellulase mutant and application thereof | 潍坊康地恩生物科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-108883180-B | CLEC9A binding agents and uses thereof | 奥里尼斯生物科学私人有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-109843923-B | Single domain antibodies and variants thereof against CTLA-4 | 南京传奇生物科技有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113584003-B | Beta-mannase mutant with improved heat resistance, and coding gene and application thereof | 河南省科学院生物研究所有限责任公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-116390939-A | Multispecific binding agents and uses thereof | 埃克塞里艾克西斯公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116390755-A | anti-PD-1/CD 40 bispecific antibodies and uses thereof | 祐和医药科技(北京)有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-113980948-B | High-activity tyrosine phenol lyase mutant | 天津大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116390948-A | Bifunctional molecules | 苏州创胜医药集团有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-114836451-B | Aryloxyphenoxy propionate herbicide hydrolytic esterase with chiral selectivity and application thereof | 淮北师范大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116391034-A | Optimized protein linkers and methods of use | 成对植物服务股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116390750-A | SARS-CoV-2 vaccine and antibody | 罗格斯新泽西州立大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-114410605-B | Method for promoting extracellular expression of recombinant protein by utilizing cutinase mutant | 江南大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-109071663-B | Bispecific signaling agents and uses thereof | 奥里尼斯生物科学私人有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-110494553-B | Process for producing theanine | 协和发酵生化株式会社 | 2023-07-04 | — | — | CN | disclosed |
| CN-116390651-A | Methods of modulating gastrointestinal metabolites | 帝斯曼知识产权资产管理有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116390951-A | PD-L1 binding agents and uses thereof | 埃克塞里艾克西斯公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-114702597-B | Construction and application of engineering bacteria for expressing plant antibacterial peptide Ct-AMP1 | 五康生物科技股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116355098-A | Trispecific antibodies and uses thereof | 上海健信生物医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116367734-A | Protein purification method at alkaline pH | 非凡食品有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-109937257-B | Method for producing target substance | 味之素株式会社 | 2023-06-30 | — | — | CN | disclosed |
| CN-113603792-B | Recombinant bone morphogenetic protein-2 and preparation method and application thereof | 深圳市人民医院 | 2023-06-30 | — | — | CN | disclosed |
| CN-116368233-A | Engineered biosynthetic pathway for the production of 4-aminophenylamine by fermentation | 齐默尔根公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116355095-A | Antibodies and bispecific antibodies targeting TIGIT and uses thereof | 上海健信生物医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113980101-B | Actinobacillus pleuropneumoniae subunit vaccine | 江苏南农高科技股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-111684057-B | Bacterial cellulose high-yield bacterial strain and preparation method of cellulose tablet by using bacterial cellulose high-yield bacterial strain | 株式会社现代百朗德 | 2023-06-30 | — | — | CN | disclosed |
| CN-110248959-B | anti-TAU antibodies and methods of use | 基因泰克公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-112195162-B | Rice leaf senescence control gene ES2 and application thereof | 浙江师范大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-112779237-B | DNA polymerase mixture for hepatitis B virus detection | 广州达安基因股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116368155-A | Multi-paratope anti-PD-1 antibodies and uses thereof | 潘迪恩运营公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116368153-A | ZIP12 antibodies | IP2IPO创新有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-109790215-B | Heterodimeric immunoglobulin constructs and methods of making the same | 北京韩美药品有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116355981-A | Method for preparing L-ascorbic acid-2-glucoside by cyclodextrin glycosyltransferase and application thereof | 弈柯莱生物科技(上海)股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-20230203749-A1 | ANTIVIRAL FABRIC | AMOGREENTECH CO., LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
| US-20230201405-A1 | ANTIVIRAL FILTER MEDIUM, AND AIR FILTER UNIT AND AIR CONDITIONER INCLUDING SAME | AMOGREENTECH CO., LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
| CN-110612310-B | anti-CLDN-5 antibodies and medicaments containing the same | 国立大学法人大阪大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-110062579-B | Engineered pesticidal proteins and methods of controlling plant pests | 先正达参股股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116348487-A | Anti-amyloid beta antibodies | 欧萨尔普罗席纳有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116334044-A | Tobacco nicotine accumulation related gene NtBGLU1, protein and application thereof | 湖南中烟工业有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116348599-A | PD-1 binding antibodies and uses thereof | 博奥信生物技术（南京）有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116348590-A | Poly-3-hydroxyalkanoates having vinyl moieties and process for producing the same | 普立费姆加拿大股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114381468-B | Methionine lyase and encoding gene and application thereof | 湖北工业大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-112813098-B | Artificial mutation for creating maize bhlh51 male sterile line | 北京科技大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116348106-A | Halogenated nupharicin derivatives and methods of use | 恩维瑞克生物科学加拿大公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-113846069-B | Amphetamine dehydrogenase mutant and application thereof in chiral amine synthesis | 华东理工大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116348478-A | HER2/4-1BB bispecific fusion proteins for use in cancer treatment | 皮里斯制药有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-110621338-B | Broad spectrum neutralizing anti-HIV-1 antibodies and methods of use thereof | 洛克菲勒大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116284412-A | anti-MASP-2 antibody and preparation method and application thereof | 沈阳三生制药有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323952-A | LYSM receptor motif | 奥尔胡斯大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116286562-A | Genetically engineered bacterium and preparation method and application thereof | 虹摹生物科技(上海)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323668-A | Therapeutic antibodies and uses thereof | 辉瑞公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323656-A | Gating adapter targeting receptors | 优莫佳生物制药股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-108174604-B | Bispecific CAR T cells for solid tumor targeting | 西雅图儿童医院（DBA西雅图儿童研究所） | 2023-06-23 | — | — | CN | disclosed |
| CN-116322738-A | Vasopressin-2 receptor antagonistic peptide and use thereof | 原子能与替代能源委员会 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323634-A | Modification of protein oligomers forming nanopores | 牛津纳米孔科技公开有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116322783-A | Conjugate of single domain antibody, saponin and effector molecule, pharmaceutical composition comprising same, therapeutic use of said pharmaceutical composition | 萨普雷米科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323646-A | Recombinant algae with high lipid productivity | 维里多斯公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116322785-A | Dual cytokine fusion proteins comprising IL-10 | 德卡生物科学公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116322725-A | Extracellular vesicles with immunomodulators | 变色龙生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114874316-B | Water-soluble collagen and application thereof | 重庆大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323641-A | Engineered AAV vectors | 路德维希-马克西米利安慕尼黑大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-114540385-B | Method for producing lysostaphin by using escherichia coli | 齐鲁工业大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-114657186-B | Phyllostachys pubescens leaf shape regulating gene PheLBD29 and application thereof | 安徽农业大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-114805481-B | Short peptide and slow release preparation with long-acting analgesic or/and long-acting local anesthetic effect by taking short peptide as carrier material | 四川大学华西医院 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323675-A | anti-CD 47 antibodies and methods of use | 上海复宏汉霖生物技术股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116323935-A | Enzymes and enzyme compositions for cleaning | 丹尼斯科美国公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20230192777-A1 | EPITOPIC VACCINE FOR AFRICAN SWINE FEVER VIRUS | ESCALATE CAPITAL V, LP | 2023-06-22 | — | — | US | disclosed |
| CN-114657199-B | Recombinant engineering bacterium and application thereof in preparation of D-pantothenic acid | 安徽华恒生物科技股份有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-111690586-B | Method for enhancing intracellular propionyl coenzyme A metabolism and improving steroid precursor production | 天津科技大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-108601825-B | Vaccine composition | 巴拉特生物技术国际有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114957490-B | PCV2-PCV3 fusion protein, and preparation method, gene, recombinant vector and application thereof | 龙湖现代免疫实验室 | 2023-06-20 | — | — | CN | disclosed |
| CN-113337476-B | Foot-and-mouth disease O-type PanASia-2 pedigree reserve vaccine strain, construction method and application thereof | 中国农业科学院兰州兽医研究所 | 2023-06-20 | — | — | CN | disclosed |
| CN-114657200-B | Recombinant engineering bacterium and method for preparing D-pantoic acid by using same | 安徽华恒生物科技股份有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114657198-B | Recombinant engineering bacterium and application thereof in preparation of panto-compound | 安徽华恒生物科技股份有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-113166258-B | Recombinant proteins targeting PD-L1 and VEGF | 宜明昂科生物医药技术（上海）股份有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-112390895-B | CK20 antigen, hybridoma cell strain, monoclonal antibody and application thereof | 河南赛诺特生物技术有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-116262787-A | Anti-human LAG-3 monoclonal antibody, and preparation method and application thereof | 博奥信生物技术（南京）有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-113061542-B | Pichia pastoris engineering bacteria capable of producing conjugated linoleic acid and application thereof | 江南大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-109641941-B | Methods for purifying and activating botulinum neurotoxin | 哈佛大学校长及研究员协会 | 2023-06-16 | — | — | CN | disclosed |
| CN-115044569-B | Taq DNA polymerase mutant and application thereof | 武汉爱博泰克生物科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-114703200-B | Apple drought-enduring negative regulation gene MdbHLH108 and application thereof | 河南农业大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-110658337-B | Diagnosis and treatment of autoimmune diseases | 武田药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| CN-113195530-B | Antibody fusion protein, preparation method and application thereof | 长春金赛药业有限责任公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-112574309-B | anti-PD-L1 nano antibody and application thereof | 启愈生物技术(上海)有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-116262921-A | Gene HHC4 for controlling rice grain length and yield and application thereof | 中国科学院植物研究所 | 2023-06-16 | — | — | CN | disclosed |
| US-20230182139-A1 | EVACUATED BLOOD COLLECTION TUBES CONTAINING PROTEASE INHIBITORS FOR THE ASSESSMENT OF CONTACT SYSTEM ACTIVATION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-06-15 | — | — | US | disclosed |
| US-20230180791-A1 | ANIMAL FEED COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2023-06-15 | — | — | US | disclosed |
| CN-109689688-B | anti-ICOS antibodies | 科马布有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-109475603-B | anti-PD-L1 antibodies | 科马布有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-116261469-A | Combinations comprising an ADC or AOC containing a VHH and a saponin or ligand-saponin conjugate | 萨普雷米科技有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-114395547-B | Mutant of beta-galactosidase and application of mutant in milk | 江南大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-116253802-A | Multispecific T cell cement comprising LRRC15 antigen binding domain | 苏州泽璟生物制药股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-116261597-A | Production of Fuc-a1,2-Gal-R in the alpha-1, 3 glycosylated form | 因比奥斯公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-112839512-B | Enzymatic compositions for carbohydrate antigen cleavage on donor organs, methods and uses related thereto | 不列颠哥伦比亚大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114539374-B | GmZTL3 protein, application of encoding gene thereof and method for cultivating soybeans | 东北农业大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-112852842-B | Alternan sucrase expression and method for preparing alternan by using same | 江南大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-111971060-B | Bifunctional molecules that recruit antibodies and target tumor cells | 江南大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-116254245-A | Application of protein OPAA114644 as organic phosphoric acid anhydrase | 中国科学院微生物研究所 | 2023-06-13 | — | — | CN | disclosed |
| CN-110559432-B | Eimeria acervulina nano subunit vaccine and preparation method and application thereof | 南京农业大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114645057-B | Caragana microphylla drought-tolerant gene Chr8.229 and application thereof in preparation of drought-tolerant transgenic plants | 兰州大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-113201513-B | Heat-resistant dextranase mutant as well as preparation method and application thereof | 广西产研院生物制造技术研究所有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114958807-B | Alkali-resistant lipase mutant and application thereof | 山东隆科特酶制剂有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114940997-B | Application of GmBBE-like43 gene in regulating and controlling plant to adapt to low-phosphorus and acid aluminum stress and promote growth | 华南农业大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-116249711-A | SARS-CoV-2 neutralizing antibodies or fragments thereof | 庆应义塾 | 2023-06-09 | — | — | CN | disclosed |
| CN-114349865-B | PD-1/LAG-3 tetravalent bispecific antibody, preparation method and application thereof | 三生国健药业（上海）股份有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116249709-A | Multimeric immunomodulators targeting 4-1BB | 皮里斯制药有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-112794888-B | BtSAMS1 protein from teosintes and application thereof in aphid-resistant plant breeding | 山西师范大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-114015665-B | Engineered NADPH-dependent phenylglycine dehydrogenase and application thereof | 中山大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-110382542-B | Bispecific antigen binding molecules to costimulatory TNF receptors | 豪夫迈·罗氏有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116240246-A | Method for synthesizing calcitol by using peroxidase | 浙江金朗博药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-113699132-B | Application of cyclodextrin glucosyltransferase from bacillus circulans and glycosylation method of ginsenoside compound | 上海中医药大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-116249559-A | Anti-idiotype compositions and methods of use thereof | 埃克苏马生物技术公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116249773-A | NBP-14 for use in the treatment of Alzheimer's disease associated with Down's syndrome | 神经生物有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116249781-A | Production of biological products containing GlcNAc in cells | 因比奥斯公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114990137-B | Arabidopsis thaliana calbindin gene AtCAREF and application thereof | 鲁东大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-116249778-A | Polynucleotides encoding amino acid sequences and encoding oxidoreductases | 赢创运营有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116249547-A | Brain-specific angiogenesis inhibitor 1 (BAI 1) antibodies and uses thereof | 代码生物疗法公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2023099927-A1 | METHOD FOR THE PREPARATION OF A RECOMBINANT TYPE II TRANSMEMBRANE PROTEASE SERINE FRAGMENT, SAID FRAGMENT, AND ITS USE | EVOLVERITAS BIOTECHNOLÓGIAI KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG (HU) | 2023-06-08 | — | — | WO | disclosed |
| EP-4189398-A1 | P53 POST-TRANSLATIONAL MODIFICATIONS AS MARKERS IN THE DIAGNOSIS AND PROGNOSIS OF A NEURODEGENERATIVE DISEASE | Diadem S.p.A. (IT) | 2023-06-07 | — | — | EP | disclosed |
| CN-116234583-A | ARRDC1 mediated microbubble-based delivery to the nervous system | 哈佛大学的校长及成员们 | 2023-06-06 | — | — | CN | disclosed |
| CN-116234567-A | Method for assembling two-component virus-like particles | Icosavax股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-114045230-B | Actinomycetes for promoting plant root growth and application thereof | 中国农业科学院农业环境与可持续发展研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-114231546-B | Neutral cellulase optimization gene and preparation method and application thereof | 武汉新华扬生物股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116235054-A | Method for determining a subject's predisposition from a light-medium COVID-19 disease course to a severe or critical disease course | 赛欧米克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116234913-A | Engineered microorganisms for diagnostic imaging | 微生物机器公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116234820-A | Methods and compositions for purifying trimeric fusion proteins | 四川三叶草生物制药有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-114478751-B | Application of diaphorina citri insulin receptor gene DcIR in prevention and treatment of diaphorina citri | 华南农业大学 | 2023-06-06 | — | — | CN | disclosed |
| US-11667684-B2 | Methods and compositions for regenerating tissues | NellOne Therapeutics, Inc. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11668718-B2 | Peptide quantitation assay for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-06-06 | — | — | US | disclosed |
| CN-116234558-A | Engineered T cells conditionally expressing recombinant receptors, related polynucleotides and methods | 朱诺治疗学有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116235055-A | Post-p 53 modification as a marker for diagnosis and prognosis of neurodegenerative diseases | 戴尔戴莫股份公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-109863244-B | GH9 endoglucanase variants and polynucleotides encoding same | 诺维信公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116209676-A | LAIR-1 binders and methods of use thereof | 恩格姆生物制药公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-115160419-B | Pichia glabra Thioredoxin secretory protein and application thereof | 西南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-109312312-B | HbA1c dehydrogenase | 龟甲万株式会社 | 2023-06-02 | — | — | CN | disclosed |
| CN-114349866-B | PD-1/TGF-beta tetravalent bispecific antibody, preparation method and application thereof | 三生国健药业（上海）股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-115160417-B | Pichia glabra Glyco_hydro secretion protein and application thereof | 西南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-116209674-A | KRAB fusion repressors and methods and compositions for repressing gene expression | 多伦多大学管理委员会 | 2023-06-02 | — | — | CN | disclosed |
| CN-114457117-B | Dendritic cell tumor vaccine and use thereof | 深圳市珈钰生物科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-113651889-B | anti-EphA 2 fully human bivalent recombinant antibody scFv-Fc | 西南医科大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114262379-B | PD-1/VEGF tetravalent bispecific antibody, preparation method and application thereof | 三生国健药业（上海）股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-115160418-B | Pichia glabra Peptidase secretion protein and application thereof | 西南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113603779-B | Antibody combined with human lymphocyte activation gene 3 (LAG-3) and application thereof | 深圳市元谷生物科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-110050064-B | Dengue virus-like particles, dengue virus antibodies and compositions containing same | 赵黛瑜 | 2023-06-02 | — | — | CN | disclosed |
| CN-116200362-A | Taq enzyme mutant and preparation method and application thereof | 广州达安基因股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-116200363-A | Taq enzyme mutant, preparation method and application thereof | 广州达安基因股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-116196995-A | Vaccum blood collection tubes containing protease inhibitors for assessing contact system activation | 武田药品工业株式会社 | 2023-06-02 | — | — | CN | disclosed |
| CN-116179372-A | Engineering bacterium for producing tetrahydroanthracene compound and method for producing anthraquinone compound | 上海中医药大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-116194480-A | Method for redirecting IL-2 to target cells of interest | 百时美施贵宝公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-114805519-B | Application of natural Qiya seed polypeptide in aspect of gonadal function regulation | 灶灶科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115322257-B | BCMA targeting antibody, chimeric antigen receptor and application thereof | 上海优替济生生物医药有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116194483-A | Methods of cancer treatment using anti-CD 73 antibodies | 先天制药公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116178560-A | Snake venom antigen epitope chimeric body, antibody, preparation method and application thereof | 上海赛伦生物技术股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-113249344-B | Herbicide-resistant muteins, nucleic acids and their use | 山东舜丰生物科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-112672759-B | Antitumor use of anti-apoptotic ligand-1 (PD-L1) antibodies | 四川科伦博泰生物医药股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-111500549-B | Enzyme for preparing C1, 2-dehydrogenation steroid compound and application thereof | 湖北工业大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-115466331-B | Chimeric antigen receptor targeting BCMA and application thereof | 合源生物科技(天津)有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-113105534-B | Application of WRKY55 transcription factor in plant salt resistance | 山东师范大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-116194132-A | Peptide adjuvants for their therapeutic use in the development of viral and tumor vaccines, in cancer immunotherapy and diagnosis and treatment of autoimmune diseases | 新加坡国立大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-114507284-B | Antibodies against TIGIT, methods of preparation and uses thereof | 华博生物医药技术（上海）有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-114752581-B | Alpha-galactosidase mutant and application thereof | 南京工业大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-116171168-A | Enhancing immune responses by targeting antigen expression | 罗特格斯新泽西州立大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-116171107-A | Nitro compound detection element | 住友化学株式会社 | 2023-05-26 | — | — | CN | disclosed |
| CN-111699200-B | Single domain antibodies and variants thereof against PD-1 | 南京传奇生物科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-116171322-A | Method for preparing purified rhabdovirus from cell culture | 勃林格殷格翰国际有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-113755478-B | Method for changing activity or function of 2, 3-oxidation squalene cyclase | 东北林业大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-112004411-B | Transgenic chicken producing human antibody | 晶体生物科学股份有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-108603219-B | Modified nucleotide reagents | 加利福尼亚太平洋生物科学股份有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-113896793-B | Monoclonal antibody for resisting human IL-17RC and application thereof | 港科鹏禾生物(苏州)有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-109793893-B | VISTA modulators for diagnosis and treatment of cancer | 达特茅斯大学理事会 | 2023-05-26 | — | — | CN | disclosed |
| WO-2023089542-A1 | PEPTIDES AND USES THEREOF | PreveCeutical Medical Inc. (CA) | 2023-05-25 | — | — | WO | disclosed |
| CN-107847574-B | PD-1 binding molecules and methods of use thereof | 宏观基因有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-113881700-B | Application of arabidopsis AtSR33 gene in inhibiting turnip mosaic virus infection | 中国农业科学院植物保护研究所 | 2023-05-23 | — | — | CN | disclosed |
| CN-113683690-B | Antibody for yellow fever virus NS1 protein and application thereof | 中国科学院微生物研究所 | 2023-05-23 | — | — | CN | disclosed |
| CN-116157125-A | Combination of T cell therapy and immunomodulatory compounds for BCMA | 朱诺治疗学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116157116-A | Methods and compositions for producing viral fusions | 旗舰先锋创新V股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116157141-A | Method for preparing freeze-dried protein formulation | 美国安进公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-114524866-B | Plant endogenous gene and protein for influencing feeding of lepidopteran insects | 沧州市农林科学院 | 2023-05-23 | — | — | CN | disclosed |
| CN-116143937-A | Immune cells with enhanced function and uses thereof | 立凌生物制药(苏州)有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-109476748-B | Methods for treatment and diagnosis of cancer | 豪夫迈·罗氏有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-113373159-B | SlTGLa10 gene related to low-temperature resistance of tomatoes, silencing vector and application thereof | 西北农林科技大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-113403289-B | Mutant p-hydroxyphenylpyruvate dioxygenase, nucleic acid encoding same, and use thereof | 青岛清原种子科学有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116157389-A | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116157514-A | Novel OMNI-59, 61, 67, 76, 79, 80, 81 and 82CRISPR nucleases | 埃门多生物公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-113621058-B | Yellow fever virus antibody and application thereof | 中国科学院微生物研究所 | 2023-05-23 | — | — | CN | disclosed |
| CN-113683691-B | Flavivirus antibodies and uses thereof | 中国科学院微生物研究所 | 2023-05-23 | — | — | CN | disclosed |
| CN-116135884-A | anti-TIGIT-anti-PD-L1 bispecific antibodies, pharmaceutical compositions and uses thereof | 普米斯生物技术(珠海)有限公司 | 2023-05-19 | — | — | CN | disclosed |
| CN-116135981-A | Method for synthesizing malonic acid and application | 中国科学院天津工业生物技术研究所 | 2023-05-19 | — | — | CN | disclosed |
| US-20230151081-A1 | CELLULAR FACTORS INVOLVED IN THE CYTOTOXICITY OF STAPHYLOCOCCUS AUREUS LEUKOCIDINS: NOVEL THERAPEUTIC TARGETS | UNIV NEW YORK (US) | 2023-05-18 | — | — | US | disclosed |
| EP-4178626-A2 | UNIVERSAL CAR-NK CELL TARGETING VARIOUS EPITOPES OF HIV-1 GP160 | University of Southern California (US) | 2023-05-17 | — | — | EP | disclosed |
| CN-116121258-A | Application of soybean ABC total transporter GmABCC3 coding gene | 南京农业大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-109468348-B | Adipic acid ester or thioester synthesis | 基因组股份公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-107691443-B | Compounds useful as alternative oxidase or cytochrome bc1 complexes | 萨塞克斯大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-114908068-B | Pear callose synthase PbrCalS5 and encoding gene and application thereof | 南京农业大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-113637068-B | Recombinant I-type humanized collagen C1L5T and preparation method and application thereof | 山西锦波生物医药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-110156892-B | anti-PD-L1 antibodies and their use as therapeutic and diagnostic agents | 百济神州有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116134133-A | Novel non-naturally occurring CRISPR-CAS nucleases for genome editing | BRAIN生物技术有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116134027-A | Heteroaryl-substituted 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116134046-A | Methods and compositions for protein sequencing | 宽腾矽公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116134143-A | Multiple disease resistance genes and genome stacks thereof | 先锋国际良种公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116134052-A | Multispecific antibodies | 努玛治疗有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-114875043-B | Betula alba BpPIF4 gene participating in adventitious root development and application thereof | 东北林业大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-115216456-B | Thermophilic ribonucleoside kinase mutant and application thereof | 华东理工大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-116113645-A | Modified nicotinamide riboside phosphate transferase | 三菱化学株式会社 | 2023-05-12 | — | — | CN | disclosed |
| CN-113330037-B | Bivalent bispecific antibody, preparation method thereof, encoding gene, host cell and composition | 长春金赛药业有限责任公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114085293-B | Recombinant protein for preventing poultry ankara disease, construction method and application | 吉林大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-116103239-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114736277-B | Forward regulatory factor for regulating salt tolerance of corn, inDel molecular marker thereof and application of forward regulatory factor | 河南农业大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-116098986-A | Keratin 7 protein, recombinant plasmid expressing Keratin 7 protein, recombinant probiotics and application | 兰州大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-110294807-B | anti-TIM-3 antibodies | 新加坡科技研究局 | 2023-05-12 | — | — | CN | disclosed |
| CN-114317565-B | Starch branching enzyme from myxobacteria, gene thereof, engineering bacteria containing gene and application of engineering bacteria | 南京农业大学 | 2023-05-12 | — | — | CN | disclosed |
| EP-4175503-A1 | REDUCTION OF VIRAL INFECTIONS | Phoxbio Limited (IE) | 2023-05-10 | — | — | EP | disclosed |
| CN-116082515-A | Foot-and-mouth disease virus capsid fusion protein soluble expressed in escherichia coli and preparation method thereof | 浙江海隆生物科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116096230-A | Method for controlling meristem size to improve crops | 成对植物服务股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116096757-A | anti-HLA-DQ 2.5 antibodies and their use in the treatment of celiac disease | 中外制药株式会社 | 2023-05-09 | — | — | CN | disclosed |
| CN-110615843-B | Chimeric antigen receptor containing third signal receptor and application thereof | 上海隆耀生物科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116096756-A | Antibodies against ILT2 and uses thereof | 比昂生物制剂公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114409770-B | Setaria fever virus humanized monoclonal antibody and application thereof | 中国科学院微生物研究所 | 2023-05-09 | — | — | CN | disclosed |
| CN-111019918-B | Glycosyltransferase mutant and application thereof | 广东广业清怡食品科技股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116096733-A | Antigen-specific immunotherapy of covd-19 fusion proteins and methods of use | 阿卡斯通生物科学公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116096485-A | Flow channel structure, method for stirring fluid, and method for producing lipid particles | 株式会社东芝 | 2023-05-09 | — | — | CN | disclosed |
| CN-116083398-A | Isolated Cas13 proteins and uses thereof | 广州瑞风生物科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114409769-B | Setaria fever virus humanized monoclonal antibody and application thereof | 中国科学院微生物研究所 | 2023-05-09 | — | — | CN | disclosed |
| CN-110312736-B | PD-L1 binding polypeptides or compounds | 苏州康宁杰瑞生物科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116082466-A | African swine fever virus CD2V epitope peptide, application thereof and anti-African swine fever virus CD2V monoclonal antibody | 郑州大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-116075523-A | Recombinant proteins with fused interferon-beta muteins and antibodies and pharmaceutical compositions comprising the same | 基因制药株式会社 | 2023-05-05 | — | — | CN | disclosed |
| CN-112961888-B | Application of recombinase in synthesis of glucan containing alpha- (1, 2) glycosidic bond | 东北师范大学 | 2023-05-05 | — | — | CN | disclosed |
| CN-113755505-B | Vaccine for treating and/or preventing African swine fever virus and preparation method thereof | 绵阳市游仙区创新科技产业技术研究院 | 2023-05-02 | — | — | CN | disclosed |
| CN-114645058-B | Caragana microphylla drought-tolerant gene Chr8.231 and application thereof in preparation of drought-tolerant transgenic plants | 兰州大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-113528490-B | Chitinase, coding gene and application thereof | 昆明理工大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-112239490-B | Method for screening lanthionin, cell-free protein synthesis system and lanthionin | 武汉合生科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-116056729-A | Method for degrading endogenous proteins | 南卡罗莱纳大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-116057181-A | Methods and compositions for modifying and delivering lymphocytes | 埃克苏马生物技术公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110862999-B | Rice inositol polyphosphate kinase gene OsIPK2 and application of encoded protein thereof | 中国水稻研究所 | 2023-05-02 | — | — | CN | disclosed |
| CN-113061541-B | Recombinant saccharomyces cerevisiae and application thereof in production of conjugated linoleic acid | 江南大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-116034168-A | Coronavirus diagnostic compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116024175-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116034163-A | Humic substances for producing erythritol | 康齐尔庄园有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023447-A | BmoR mutant-based wide-area biosensor | 北京理工大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115073599-B | Antibodies that bind PD-L1 and uses thereof | 北京天广实生物技术股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-108289933-B | Secreted splice variants of mammalian Klotho as cognitive and behavioral impairment drugs | 巴塞罗那自治大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-113316636-B | DNA polymerase with improved enzymatic activity and use thereof | 深圳华大生命科学研究院 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023503-A | Fusion protein and preparation method and application thereof | 上海交通大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-116033940-A | Activating endogenous antibacterial agent for treating SARS-COV-2 infection | 艾尔金制药有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112266923-B | Bacillus subtilis for expressing adenomethionine synthase and application thereof | 江南大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-111254170-B | Method for preparing (S) -1,2,3, 4-tetrahydroisoquinoline-3-formic acid by multienzyme coupling | 浙江大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-113249240-B | Saccharomyces cerevisiae for high yield of hydroxytyrosol and construction method thereof | 天津大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-116019916-A | Application of non-small cell lung cancer target ARID1A and inhibitor thereof in preparation of lung cancer treatment drugs | 蚌埠医学院第一附属医院 | 2023-04-28 | — | — | CN | disclosed |
| CN-109939227-B | Ragweed pollen allergen extract, extract liquid and preparation method thereof | 中国医学科学院北京协和医院 | 2023-04-28 | — | — | CN | disclosed |
| CN-109679992-B | Use of insecticidal proteins | 北京大北农生物技术有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112553183-B | Glycoside hydrolase CmChi3 and application thereof in degradation of hydrocolloid chitin | 南京工业大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-114040925-B | anti-SIRP alpha monoclonal antibody and application thereof | 礼新医药科技(上海)有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116034115-A | Vaccine compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-113748212-B | Enzymatic process for preparing GDP-fucose | 马克斯·普朗克科学促进学会 | 2023-04-25 | — | — | CN | disclosed |
| CN-116003542-A | Microorganism for producing citric acid, construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2023-04-25 | — | — | CN | disclosed |
| CN-113181350-B | Peptide vaccine based on activated fibroblast growth protein (FAP) and preparation method thereof | 浙江大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-111278865-B | Novel recombinant fusion proteins, their preparation and use | 盛禾(中国)生物制药有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-111961673-B | Rice grain type gene GS10 and application thereof | 中国水稻研究所 | 2023-04-25 | — | — | CN | disclosed |
| CN-113999807-B | Construction method of recombinant strain and application of recombinant strain in itaconic acid production | 南京工业大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-116018157-A | HIV vaccine compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-114836404-B | Composite heat-resistant cellulase and preparation method and application thereof | 陕西理工大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-116018407-A | Modified terpene synthases and their use for the production of pseudopterosin intermediates and/or pseudopterosins | 慕尼黑科技大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-112760297-B | Coronavirus pseudovirus packaging system, packaging method thereof and application of coronavirus pseudovirus in evaluating disinfection efficacy | 睿丰康生物医药科技(浙江)有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-112779273-B | Artificially synthesized high-toxicity insecticidal gene for spodoptera frugiperda and application thereof | 中国农业科学院生物技术研究所 | 2023-04-25 | — | — | CN | disclosed |
| CN-114621350-B | Chimeric immunoglobulins | 东莞市朋志生物科技有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115996756-A | Elastase substrate peptide linker immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115996693-A | Perfume delivery mechanism, method and use thereof | 米尼翁大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115997004-A | Low diacetyl yeast | 嘉士伯有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-114933649-B | Antibodies against varicella-zoster virus and uses thereof | 北京智仁美博生物科技有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115997051-A | Protein scaffold | 尼克法玛株式会社 | 2023-04-21 | — | — | CN | disclosed |
| CN-115141280-B | Taq DNA polymerase monoclonal antibody and application thereof | 广东和信健康科技有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-110713537-B | SEMA4D antibody and preparation method and application thereof | 江苏怀瑜药业有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115991747-A | BmoR mutant-based high-sensitivity biosensor | 北京理工大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115996760-A | Binding agents for central nervous system delivery and uses thereof | 阿鲁纳生物股份公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115996951-A | anti-CD 103 antibodies | 赛罗帕私人有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-114107340-B | Mevalonate kinase gene RKMK and application thereof | 昆明理工大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115991746-A | Bmor mutant specifically responding to isobutanol and application thereof | 北京理工大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-113166252-B | Fully human anti-GITR antibodies and methods of making same | 上海开拓者生物医药有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115991748-A | BmoR mutant-based high-sensitivity biosensor | 北京理工大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115996754-A | Prophylactic and therapeutic immunotherapy of propionibacterium acnes | 免疫之源生物技术有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-113698469-B | Method and reagent for capturing host cell membrane-associated protein of SVCV | 深圳大学 | 2023-04-21 | — | — | CN | disclosed |
| US-20230123357-A1 | USE OF DOWNSTREAM FACTORS IN THE KLOTHO PATHWAY TO ASSESS KLOTHO ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-04-20 | — | — | US | disclosed |
| US-20230121387-A1 | METHODS AND COMPOSITIONS FOR TREATING MUSCLE ATROPHY | NellOne Therapeutics, Inc. (US) | 2023-04-20 | — | — | US | disclosed |
| CN-115976118-A | Method and carrier for biologically synthesizing nootkatone | 武汉合生科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114686497-B | Gene MnGutB1 for improving DNJ biosynthesis of mulberry and application thereof | 西南大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115989036-A | RSV vaccine compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-109705213-B | Anti-staphylococcus aureus toxin antibody and application thereof | 上海长征医院 | 2023-04-18 | — | — | CN | disclosed |
| CN-115989412-A | Rapid and simple antibody detection using covalently immobilized self-assembled polypeptides | 西西欧艾(杭州)生物医药有限责任公司 | 2023-04-18 | — | — | CN | disclosed |
| US-11629321-B2 | Scaffold for cell culture or tissue engineering | AMOLIFESCIENCE CO., LTD. (KR) | 2023-04-18 | — | — | US | disclosed |
| CN-108350496-B | Polymerase compositions and kits, and methods of use and manufacture thereof | 生命技术公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113462676-B | Method for displaying lyase on cell surface and application thereof | 百葵锐(天津)生物科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113429468-B | Barley male sterility gene msg3002 and application thereof | 山东农业大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-111154767-B | Root length regulatory gene LOGL5, corresponding construct and application thereof | 未名生物农业集团有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113584054-B | DNA molecules encoding arginine deiminase and uses thereof | 河北远大九孚生物科技有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115975003-A | TCRs, polypeptides, expression vectors, host cells, pharmaceutical compositions, and methods for obtaining TCRs | 科士华(南京)生物技术有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-112538106-B | ELISA detection method and kit for mycoplasma synoviae antigen protein LP85 and corresponding antibody | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 2023-04-14 | — | — | CN | disclosed |
| CN-108976300-B | PD-1 binding molecules and methods of use thereof | 宏观基因有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-111788228-B | Anti-claudin 18.2 antibodies and uses thereof | 礼新医药科技(上海)有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-108368174-B | FGFR2 inhibitors alone or in combination with immunostimulants for cancer treatment | 戊瑞治疗有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-110343684-B | Pear fruit vacuole acidic invertase and application of activity inhibitor thereof | 南京农业大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-114560911-B | Antifungal peptide and preparation method thereof | 中国农业大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-109641947-B | CD229CAR T cells and methods of use thereof | 犹他大学研究基金会 | 2023-04-14 | — | — | CN | disclosed |
| CN-109844536-B | Predicting response to PD-1 axis inhibitors | 豪夫迈·罗氏有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115968410-A | Methods of characterizing polynucleotides moving through a nanopore | 牛津纳米孔科技公开有限公司 | 2023-04-14 | — | — | CN | disclosed |
| US-20230116082-A1 | METHODS AND COMPOSITIONS FOR TREATING TISSUE DAMAGE RESULTING FROM VIRAL INFECTIONS | NellOne Therapeutics, Inc. (US) | 2023-04-13 | — | — | US | disclosed |
| CN-115956090-A | Immobilized self-assembling protein multimers | 西西欧艾(杭州)生物医药有限责任公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-114106111-B | High-adhesion polypeptide and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-04-11 | — | — | CN | disclosed |
| CN-108883164-B | Antibodies to TIGIT | JN生物科学有限责任公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-113121704-B | Nanoparticle-based coronavirus vaccines | 昆山新蕴达生物科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-109415441-B | Antibodies and methods of making same | 英斯梅德股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-109734777-B | Novel peptides, peptide compositions and scaffolds for immunotherapy of various cancers | 伊玛提克斯生物技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115925891-A | Anti-influenza B virus antibody, reagent and kit for detecting influenza B virus | 东莞市朋志生物科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112063587-B | Application of super antigen or variant thereof in preparation of CAR immune cells | 中国科学院沈阳应用生态研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-115943155-A | TREM2 chimeric receptor | 圭尔医疗有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115044627-B | Method for efficiently producing L-homophenylalanine and strain for producing L-homophenylalanine | 江南大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-114107243-B | Methionine adenosyltransferase mutant | 江南大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115943160-A | anti-oxMIF/anti-CD 3 bispecific antibody constructs | 翁科奥内研发有限责任公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115943210-A | Ligand binding fusion proteins | 中外制药株式会社 | 2023-04-07 | — | — | CN | disclosed |
| CN-115943307-A | MR1 ligands and pharmaceutical compositions for immunomodulation | 巴塞尔大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115917003-A | Method for repeatedly moving double-stranded polynucleotide through nanopore | 牛津纳米孔科技公开有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916231-A | Recombinant rhabdovirus encoding CD80 ectodomain Fc fusion protein | 勃林格殷格翰国际有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916251-A | Peptide mixtures | 休博治疗有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115915927-A | Methods for inducing endogenous tandem replication events | 莱顿大学医学中心附属莱顿教学医院 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916961-A | T cells | 约奥罗波安图内斯分子医学研究所 | 2023-04-04 | — | — | CN | disclosed |
| CN-115917320-A | Method for determining free antigen of antibody in sample | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109311973-B | Antigen binding molecules comprising C-terminal fused TNF family ligand trimers | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916335-A | anti-GLP 1R antagonist antibodies and methods of use thereof | 瑞泽恩制药公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109071627-B | CD8 binding agents | 奥里尼斯生物科学私人有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-110678459-B | 2-heteroaryl-3-oxo-2, 3-dihydropyridazine-4-carboxamides for the treatment of cancer | 拜耳股份公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916199-A | Dosing regimens comprising 3- (1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives | 诺华股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916223-A | Methods and uses related to cell therapy engineered with chimeric antigen receptors targeting B cell maturation antigens | 朱诺治疗学股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916838-A | PCSK9 inhibitors and methods of their use for treating cholesterol-related disorders | 安进公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916182-A | Methods and compositions for treating triple negative breast cancer | 基因泰克公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916829-A | Compositions comprising IGE antibodies | 伦敦王室学院 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916348-A | Treatment with anti-TIGIT antibodies and PD-1 axis binding antagonists | 基因泰克公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916827-A | Immune activated Fc domain binding molecules | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916830-A | anti-CD 3/anti-CD 28 bispecific antigen binding molecules | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109689087-B | Targeted mutant interferon-beta and uses thereof | 奥里尼斯生物科学私人有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115896116-A | Termite formosana gram-negative bacteria recognition protein GNBP1 gene and application thereof | 南京林业大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916256-A | anti-SARS coronavirus type 2 spike protein antibody | 单细胞科技公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916973-A | Compositions for treating cancers with KRAS mutations and uses thereof | 阿迪根有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-109890970-B | Method for producing target substance | 味之素株式会社 | 2023-04-04 | — | — | CN | disclosed |
| CN-110121340-B | Formulation of pegylated arginine deiminase | 波拉里集团 | 2023-03-31 | — | — | CN | disclosed |
| CN-115884980-A | Peptide platinum complexes and methods of use thereof | 奥康维路士有限责任公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115873801-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115885039-A | Protein degradation | 敦提大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-113583140-B | Swine epidemic diarrhea virus Nsp10 protein, fusion protein containing Nsp10 protein, and preparation method and application thereof | 江西农业大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-114573714-B | Conjugate for target molecule modification and preparation method thereof | 北京大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-113061587-B | Antigen spectrum expanded O-type foot-and-mouth disease virus strain and construction method and application thereof | 中国农业科学院兰州兽医研究所 | 2023-03-31 | — | — | CN | disclosed |
| CN-110702913-B | Monoclonal antibody composition for quantitatively detecting coxiella burnetii I strain | 中国人民解放军军事科学院军事医学研究院 | 2023-03-31 | — | — | CN | disclosed |
| CN-113717864-B | Cellulase high-yield strain and application thereof | 青岛蔚蓝生物集团有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115884988-A | Nebulized mucus inhibiting nanobodies for the prevention of viral and microbial contamination in enclosed and semi-enclosed spaces | 小利兰·斯坦福大学托管委员会 | 2023-03-31 | — | — | CN | disclosed |
| CN-115885050-A | Methods and compositions for non-small cell lung cancer immunotherapy | 基因泰克公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-113088532-B | Gene expression switch for regulating and controlling red light and far-red light as well as construction method and application thereof | 华东师范大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-113151207-B | NAD (H) -dependent 3 alpha-hydroxysteroid dehydrogenase and gene encoding same | 重庆第二师范学院 | 2023-03-31 | — | — | CN | disclosed |
| CN-110669109-B | Enzyme-linked tag short peptide and application thereof | 上海科技大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-115873820-A | Nicotinamide mononucleotide adenyltransferase mutant | 尚科生物医药（上海）有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115873880-A | Recombinant nucleic acid sequence, recombinant expression vector and genetically engineered bacterium | 上海凯赛生物技术股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115873852-A | Recombinant nucleic acid sequence, genetic engineering bacteria and method for producing 1,5-pentanediamine | 上海凯赛生物技术股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-111218432-B | Tyrosinase precursor, encoding gene, preparation and application thereof | 中国科学院大连化学物理研究所 | 2023-03-31 | — | — | CN | disclosed |
| EP-4152945-A1 | ANIMAL FEED COMPOSITIONS | DSM IP Assets B.V. (NL) | 2023-03-29 | — | — | EP | disclosed |
| EP-4152946-A1 | ANIMAL FEED COMPOSITIONS | DSM IP Assets B.V. (NL) | 2023-03-29 | — | — | EP | disclosed |
| CN-113862280-B | Mutation site of rice ideal brittle stalk mutant IBC, control gene IBC and application thereof | 中国科学院合肥物质科学研究院 | 2023-03-28 | — | — | CN | disclosed |
| CN-115851811-A | Application of receptor kinase PXY in controlling plant bud regeneration | 陕西师范大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-115845137-A | Modified SIS (styrene-isoprene-styrene) membrane for tissue repair and preparation method and application thereof | 北京博辉瑞进生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115867565-A | Method for improving resistance to soybean rust | 成对植物服务股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115851822-A | Insect-resistant herbicide-resistant gene expression vector and application thereof | 杭州芳韵生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115851688-A | TrpCF mutant and application thereof | 胡丹 | 2023-03-28 | — | — | CN | disclosed |
| CN-114478769-B | anti-TIGIT antibody, and pharmaceutical composition and use thereof | 中山康方生物医药有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-110484545-B | Anti-mosaic virus GsCAD1 gene separated from wild soybean, encoding protein and application thereof | 东北师范大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-113493799-B | Aspergillus niger strain for high yield of acid lactase | 青岛蔚蓝生物股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115867575-A | Treatment of acute respiratory distress syndrome with IL-33 axis binding antagonists | 免疫医疗有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113493515-B | anti-CLDN 18A2 antibody and drug for treating tumor | 广东菲鹏制药股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115867649-A | TIE 2-BINDING AGENTS AND METHODS OF USE | 基因泰克公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115838707-A | Mannanase mutants | 青岛蔚蓝生物集团有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115843313-A | Recombinant herpes simplex virus for multiple targeting and uses thereof | 吉赛尔美德公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-109810999-B | Method for producing nerol by microbial fermentation | 湖北工业大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-114045305-B | Multi-swivel subsystem | 深圳市深研生物科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-114685633-B | Method for cultivating drought-resistance-changed plant, zmMADS27 protein and coding gene thereof | 中国农业大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-115838706-A | High temperature resistant mannanase mutant | 青岛蔚蓝生物集团有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115836084-A | Multispecific immunomodulators | 阿珀吉尼科斯股份公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115836129-A | Compositions and methods for treating TDP-43 proteinopathies | 索拉生物科学有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819545-A | Gene mutant and application thereof | 深圳华大生命科学研究院 | 2023-03-21 | — | — | CN | disclosed |
| CN-115836088-A | NKG 2D-, CD 16-and CLEC 12A-binding proteins | 蜻蜓疗法股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115835883-A | Method for screening antibody fragments, recombinant antibodies produced thereby and uses thereof | 刘扶东 | 2023-03-21 | — | — | CN | disclosed |
| CN-115836125-A | Use of cellulase for removing dust mites from textiles | 诺维信公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115836083-A | Yeast strain for reducing lactic acid bacteria pollution | 布鲁塞尔自由大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115811984-A | Antiviral structurally stable SARS-CoV-2 peptides and uses thereof | 丹娜法伯癌症研究院 | 2023-03-17 | — | — | CN | disclosed |
| CN-112321719-B | Drug carrier protein and application thereof | 磐石锦程生物科技(北京)有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115811987-A | Anti-ceramide antibodies | 纪念斯隆凯特琳癌症中心 | 2023-03-17 | — | — | CN | disclosed |
| CN-115812105-A | Modified filamentous fungi for production of foreign proteins | 二进国际有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115812151-A | Methods, arrays and uses thereof | 免疫媒介有限公司 | 2023-03-17 | — | — | CN | disclosed |
| WO-2023039450-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF RETINAL DEGENERATION | DUKE UNIVERSITY (US) | 2023-03-16 | — | — | WO | disclosed |
| CN-115803435-A | Method for targeted insertion of foreign sequences in the genome of a cell | 塞勒克提斯公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115803434-A | DNA polymerase variants with improved discrimination against genetic variation | 基诺泰科有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-113424797-B | Method for regulating blood brain barrier permeability and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-03-14 | — | — | CN | disclosed |
| CN-110520445-B | anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimer form bispecific antibody and preparation thereof | 北京韩美药品有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-109836480-B | Recombinant immunosuppressive protein | 陈松明 | 2023-03-14 | — | — | CN | disclosed |
| CN-115785279-A | Chimeric antigen receptor comprising novel costimulatory domains and uses thereof | 南京北恒生物科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115803054-A | Single chain antibodies and intrabodies to misfolded TDP-43 and methods of use thereof | 英属哥伦比亚大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-110592031-B | S protein fused HiBiT infectious bronchitis recombinant virus and preparation method and application thereof | 华南农业大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-115786268-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115803048-A | Compositions and methods for treating hair follicle related disorders | 亨利兹私人有限责任公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115803432-A | Recombinant herpes simplex virus with modified glycoprotein gH for retargeting and uses thereof | 吉赛尔美德公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115803324-A | Process for purifying (-) -ambrox | 奇华顿股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115772476-A | Application of filamentous fungus recombinant strain in cellulase production field | 山东大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-115772507-A | Application of cytochrome P450 enzyme in synthesis of ganoderma triterpene | 中国科学院天津工业生物技术研究所 | 2023-03-10 | — | — | CN | disclosed |
| CN-110564663-B | Controlled growth of microorganisms | 辛格隆股份公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-110724706-B | Application of Oct4 ubiquitination modified mutant in improving reprogramming efficiency of induced somatic cells | 中国科学院上海营养与健康研究所 | 2023-03-10 | — | — | CN | disclosed |
| CN-112533952-B | Compositions for treating diseases or conditions and uses thereof | 大有华夏生物医药集团有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115746143-A | Bispecific antibodies specific for co-stimulatory TNF receptors | 豪夫迈·罗氏有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115746132-A | anti-IL-17A antibodies and uses thereof | 三优生物医药(上海)有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115746125-A | Tuberculosis patient specific high-expression NK cell receptor and application thereof | 中国科学院微生物研究所 | 2023-03-07 | — | — | CN | disclosed |
| CN-115768786-A | Multispecific proteins | 分子合作伙伴股份公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115768895-A | Aptamers for the treatment of infections of the coronavirus family | 柏林制药股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115769076-A | DPP3 in patients infected with coronaviruses | 4TEEN4制药有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115768524-A | ILT binding agents and methods of use thereof | 恩格姆生物制药公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115768794-A | Methods of use of anti-TREM 2 antibodies | 艾利妥 | 2023-03-07 | — | — | CN | disclosed |
| CN-115768473-A | Bispecific antigen binding molecules targeting OX40 and FAP | 豪夫迈·罗氏有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115768791-A | Methods and treatments involving excess free LIGHT | 阿瓦洛治疗公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115768525-A | Compositions and methods for treating cancer | 天演药业(瑞士)公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-109563151-B | Methods and compositions for treating cancer | 瓦尔希伯伦私人肿瘤研究基金会 | 2023-03-07 | — | — | CN | disclosed |
| CN-115724984-A | Autoimmune B cell eliminator molecules and uses thereof | 拓创生物科技(苏州)有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-115725504-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-109072235-B | Tracking and manipulation of cellular RNA by nuclear delivery CRISPR/CAS9 | 加利福尼亚大学董事会 | 2023-02-28 | — | — | CN | disclosed |
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-113088501-B | Glutamic acid dehydrogenase mutant for producing L-glufosinate-ammonium and L-glufosinate-ammonium production method | 浙江大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-111705067-B | Wheat TaNBR1 gene and application thereof in powdery mildew resistant breeding | 天津师范大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-109563474-B | Integrated cells | 思百博技术股份公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115720521-A | Compositions and methods for preventing staphylococcus aureus infections | 安踏格尼斯公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-112695021-B | Alpha-glycosidase gene mutant and application thereof in preparation of 2-O-alpha-D-glucosyl-L-ascorbic acid | 南京工业大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-109476741-B | Molecules that bind to CD38 and PD-L1 | 拜奥穆尼克斯制药 | 2023-02-24 | — | — | CN | disclosed |
| CN-115715203-A | Methods of genetically modifying cells to deliver therapeutic proteins | 塞勒克提斯公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-113956339-B | Whitmania pigra anticoagulant factor XIa polypeptide and application thereof | 中国药科大学 | 2023-02-24 | — | — | CN | disclosed |
| US-20230056844-A1 | CELL CULTURE SUBSTRATE AND MANUFACTURING METHOD THEREFOR | AMOLIFESCIENCE CO., LTD. (KR) | 2023-02-23 | — | — | US | disclosed |
| WO-2023023560-A1 | NEW USES | CONTRAFECT CORPORATION (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023021185-A1 | ANTIGEN-BINDING POLYPEPTIDES AGAINST CD39 | Universitätsklinikum Hamburg-Eppendorf (DE) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023021151-A1 | BURDEN-ADDICTED PRODUCTION STRAINS | ENDURO GENETICS APS (DK) | 2023-02-23 | — | — | WO | disclosed |
| US-20230054852-A1 | p53 POST-TRANSLATIONAL MODIFICATIONS AS MARKERS IN THE DIAGNOSIS AND PROGNOSIS OF A NEURODEGENERATIVE DISEASE | DIADEM S.R.L. (IT) | 2023-02-23 | — | — | US | disclosed |
| CN-111607544-B | Recombinant microorganism capable of producing methyl anthranilate and method for producing methyl anthranilate using same | 韩国科学技术院 | 2023-02-21 | — | — | CN | disclosed |
| CN-109312350-B | Abiotic stress tolerant plants and methods | 未名生物农业集团有限公司 | 2023-02-21 | — | — | CN | disclosed |
| US-11584788-B2 | Compositions and methods for identification, assessment, prevention, and treatment of melanoma using PD-L1 isoforms | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| CN-109890960-B | Process for producing aldehyde | 味之素株式会社 | 2023-02-17 | — | — | CN | disclosed |
| CN-115704010-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115702926-A | Application of Versican protein in preparation of medicine for repairing damaged myocardium | 中国医学科学院阜外医院 | 2023-02-17 | — | — | CN | disclosed |
| CN-115703832-A | anti-CRR 9 monoclonal antibody with high blocking activity and application thereof | 博奥信生物技术（南京）有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115704039-A | Polynucleotides and modified cells comprising polynucleotides encoding antigen binding molecules and polynucleotides targeting ECM agents | 斯丹赛控股有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115702931-A | Application of anti-PD-L1/CD 47 bi-specific antibody in treating diseases | 百奥泰生物制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-112813049-B | Fusion protein for live cell RNA marking and application | 中国科学院分子细胞科学卓越创新中心 | 2023-02-17 | — | — | CN | disclosed |
| CN-114540324-B | DNA polymerase, aptamer, hot start DNA polymerase, and method and application | 中山大学 | 2023-02-17 | — | — | CN | disclosed |
| EP-4132956-A2 | METHODS AND COMPOSITIONS FOR TREATING TISSUE DAMAGE RESULTING FROM VIRAL INFECTIONS | Nellone Therapeutics Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115702168-A | Her 2-targeted agonistic CD28 antigen binding molecules | 豪夫迈·罗氏有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-115702247-A | Cell sorter circuit and method of use thereof | 瑞士苏黎世联邦理工大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-113684188-B | Melia azedarach leaf-shrinking virus whole genome sequence and detection method thereof | 中国计量大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-112839963-B | Novel cancer immunotherapy antibody compositions | 北京强新生物科技有限公司 | 2023-02-10 | — | — | CN | disclosed |
| CN-112924682-B | Application of urine fibrinogen alpha chain protein and polypeptide fragment thereof in normal pregnancy | 张曼 | 2023-02-10 | — | — | CN | disclosed |
| CN-111647577-B | Three-dimensional structure of RNA helicase and application thereof | 复旦大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-115698074-A | anti-CD 98 antibodies and uses thereof | 阿里亚达治疗公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114990129-B | Preparation and application of mesenchymal stem cells expressing alpha PDL1: fc fusion protein | 北京贝来生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115678913-A | Application of epigenetic factor in optimizing gene editing tool in eukaryotic cell | 中国科学院天津工业生物技术研究所 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698272-A | Production of geranyl diphosphate derived compounds | 哥本哈根大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698057-A | Antibodies against SARS-COV-2 and methods of use thereof | 维尔生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698718-A | Method and reagent for detecting pancreatic cancer | 公立大学法人横滨市立大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698719-A | Methods and compositions for cancer immunotherapy | 基因泰克公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-113265388-B | Tobacco system for producing ajmaline | 中国科学院分子植物科学卓越创新中心 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698070-A | CD5L binding antibodies and uses thereof | 德克萨斯大学系统董事会 | 2023-02-03 | — | — | CN | disclosed |
| CN-115677855-A | anti-TIGIT antibody | 山东新时代药业有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114250219-B | Balsamiferol synthase mutant and application thereof | 天津科技大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113528462-B | Phage composition and application thereof | 青岛诺安百特生物技术有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-108864276-B | NY-ESO-1-targeted T cell receptor combined expression PD 1antibody variable region and application thereof | 上海恒润达生生物科技股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115678872-A | Novel Cas13 protein and screening method and application thereof | 中国科学院脑科学与智能技术卓越创新中心 | 2023-02-03 | — | — | CN | disclosed |
| CN-115697397-A | Inoculation of polio vaccine against coronavirus | 谢七一 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698075-A | Combination therapy of cancer involving anti-ICOS and anti-PD 1 antibodies, optionally further involving anti-TIM 3 antibodies | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698717-A | Methods of treatment and diagnosis of cancer | 基因泰克公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115697077-A | Rebaudioside M sweetener compositions | 阿迈瑞斯公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115697419-A | Use of multimeric anti-DR 5 binding molecules in combination with cancer therapy to treat cancer | IGM生物科学股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698301-A | Active DNA transposable systems and methods of use thereof | 中国科学院动物研究所 | 2023-02-03 | — | — | CN | disclosed |
| CN-115698068-A | anti-TIGIT antibody | 艾库斯生物科学有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115697045-A | Method for controlling meristem size to improve crop plants | 成对植物服务股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115667523-A | Activatable cytokine constructs and related compositions and methods | 西托姆克斯治疗公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667515-A | Antibody neutralizing substance having coagulation factor VIII (F.VIII) function-replacing activity | 中外制药株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667538-A | Enzyme-mediated process for the preparation of ambroxol acetal or ambroxol acetal homologues | 奇华顿股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115666639-A | Methods and compositions for preventing adsorption of therapeutic proteins to drug delivery system components | 阿帕特夫研究和发展有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667302-A | Fusion antibody for presenting antigen-derived T cell epitope or peptide containing the epitope on cell surface, and composition containing the fusion antibody | 亚洲大学校产学协力团 | 2023-01-31 | — | — | CN | disclosed |
| CN-111850012-B | Soybean bacillus subtilis protease gene GmSub and application thereof | 吉林农业大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-109196104-B | Broad-spectrum vaccine for viral diseases | 生源霸科乌拉圭有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-106929531-B | Preparation and identification method of saccharomyces bayanus-transformed FZF1 gene sulfur-tolerant transformant | 西南林业大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667308-A | Methods of use of anti-TREM 2 antibodies | 艾利妥 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667505-A | Methods and compositions for targeted genome editing | 因特利亚治疗公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115666596-A | Combination therapy involving anti-CD 39 antibodies and adoptive cell therapy | 翠舒拉治疗股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115651931-A | Insect-resistant fusion gene M1CryAb-VIP3A, expression vector and product thereof, and application thereof | 山东省农业科学院 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667296-A | Use of anti-FAM 19A1 antagonists for the treatment of central nervous system disorders | 纽洛可科学有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113683687-B | Novel coronavirus Spike protein antibody and application thereof | 益科思特(北京)医药科技发展有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667312-A | anti-MUC 1-SEA antibodies | 生物修饰有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-111499758-B | Method for screening human potassium ion channel modulators | 中国科学院脑科学与智能技术卓越创新中心 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667298-A | Autonomous bulge domain peptides | UCB生物制药有限责任公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667537-A | Process for producing ethylene from carbon dioxide | 含氧低碳投资有限责任公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115666262-A | Animal feed composition | 帝斯曼知识产权资产管理有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667504-A | Methods and compositions for ocular cell therapy | 诺华股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115667506-A | Recombinant ACE2-FC fusion molecules and methods of making and using the same | 西雅图免疫公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2023001895-A1 | RECOMBINANT MYCOBACTERIUM AS AN IMMUNOTHERAPEUTIC AGENT FOR THE SECOND-LINE THERAPY OF BLADDER CARCINOMA | VAKZINE PROJEKT MANAGEMENT GMBH (DE) | 2023-01-26 | — | — | WO | disclosed |
| CN-112322596-B | 7 alpha-hydroxysteroid dehydrogenase mutant J-1-1 delta C6 and application thereof | 重庆大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-107586339-B | BLyS antibody and preparation method and application thereof | 尚华科创投资管理（江苏）有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-112625993-B | Preparation of alpha-ketoglutaric acid by microbial conversion method | 雅本化学股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-112851792-B | Preparation method and application of grass carp TNF-alpha recombinant protein | 山东省淡水渔业研究院（山东省淡水渔业监测中心） | 2023-01-20 | — | — | CN | disclosed |
| CN-113004422-B | Fusion protein, vaccine containing same and application thereof | 辽宁成大生物股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-114199848-B | High-throughput protein expression detection method based on protein ligase | 无锡佰翱得生物科学有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-111393531-B | Subunit fusion protein CD2V-Fc and preparation method and application thereof | 浙江海隆生物科技有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-109563157-B | Novel antibodies that specifically bind to epitopes of Zika virus and uses thereof | 胡默波斯生物医学公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-112924681-B | Application of urine KRT10 protein and polypeptide fragment thereof in normal pregnancy | 张曼 | 2023-01-17 | — | — | CN | disclosed |
| CN-112852817-B | Composition for RNA editing in III-A type CRISPR-Csm system and application | 西部(重庆)科学城种质创制大科学中心 | 2023-01-17 | — | — | CN | disclosed |
| CN-110506059-B | Bispecific antibodies that specifically bind PD1 and LAG3 | 豪夫迈·罗氏有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-111592600-B | Recombinant beta-galactosidase and construction method and application thereof | 江苏大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-114591988-B | Preparation method of genetically modified stem cells for activating tumor immunity | 北京贝来生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-111808871-B | Optimized recombination and application of 3-chlorocatechol degradation gene cluster | 上海市农业科学院（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605579-A | Metabolic engineering for the production of lipoic acid | 新加坡国立大学（SG） | 2023-01-13 | — | — | CN | disclosed |
| CN-111718910-B | FAD-dependent oxidase Ma-1 in Diels-Alder adduct anabolic pathway and application | 中国中医科学院中药研究所（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605500-A | Method for controlling meristem size to improve crop plants | 成对植物服务股份有限公司（US） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605589-A | Improved process for the production of isoprenoids | 巴斯夫欧洲公司（DE） | 2023-01-13 | — | — | CN | disclosed |
| CN-115594765-A | Bispecific antibodies specific for co-stimulatory TNF receptors | 豪夫迈·罗氏有限公司（CH） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605235-A | Collagen-based formulations useful as soft tissue fillers and/or implants | 科弗朗有限公司（IL） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605507-A | Anti-interleukin-33 antibodies and uses thereof | 基因泰克公司（US） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605504-A | Novel IL-21 prodrugs and methods of use thereof | 奥美药业有限公司（US） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605594-A | anti-IGF-1 receptor humanized antibodies | 帝人制药株式会社（JP） | 2023-01-13 | — | — | CN | disclosed |
| CN-115605494-A | Multimeric T cell modulating polypeptides and methods of use thereof | 株式会社LG化学（KR） | 2023-01-13 | — | — | CN | disclosed |
| EP-4114438-A1 | METHODS AND COMPOSITIONS FOR TREATING MUSCLE ATROPHY | Nellone Therapeutics Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| CN-110819714-B | Cancer suppressor gene and application thereof | 南方医科大学深圳医院 | 2023-01-10 | — | — | CN | disclosed |
| CN-112195170-B | Immobilized recombinant esterase and application thereof in preparing R-2, 6-dimethylphenyl aminopropionic acid | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-115583995-A | Bispecific antibody, preparation method and application thereof | 立凌生物制药(苏州)有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-114702569-B | PD-L1 related vaccine and application thereof | 深圳吉诺因生物科技有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-110208533-B | Evaluation, determination and treatment of PKAL-mediated disorders | 武田药品工业株式会社 | 2023-01-10 | — | — | CN | disclosed |
| CN-112004932-B | CRISPR/Cas effector protein and system | 中国农业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-108135547-B | Vacuum blood collection tube containing protease inhibitor for evaluating activation of contact system | 武田药品工业株式会社 | 2023-01-10 | — | — | CN | disclosed |
| CN-111979208-B | L-glutamate dehydrogenase mutant and application thereof | 弈柯莱生物科技(上海)股份有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-113214394-B | anti-IL 5 nano antibody and application thereof | 上海洛启生物医药技术有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-113307869-B | anti-IL 5 nano antibody and application thereof | 上海洛启生物医药技术有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-112391403-B | Application of TGW10 gene in improvement of crop grain type traits | 苏州今新生物科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-114516921-B | Fusion protein based on single-chain antibody fragment, nano assembly, preparation method and application thereof | 华南理工大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-111454371-B | PDL1-pHLIP, preparation method and application thereof in treatment of autoimmune disease | 北京泽勤生物医药有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-115558667-A | Gene for regulating zinc transport of chenopodium pusillum and application thereof | 内蒙古蒙草生态环境（集团）股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-110106188-B | Gene for controlling content of carotenoid in soybeans and application thereof | 中国科学院东北地理与农业生态研究所 | 2023-01-03 | — | — | CN | disclosed |
| CN-115551546-A | Coronavirus vaccine | 帝国理工创新有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115552026-A | Enzymatic method for preparing CMP-Neu5Ac | 马克斯·普朗克科学促进学会 | 2022-12-30 | — | — | CN | disclosed |
| CN-109071632-B | Targeted therapeutic agents and uses thereof | 奥里尼斯生物科学私人有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115552245-A | Bioinformatics | 赫尔辛基大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-111406069-B | anti-CTLA 4 antibodies and uses thereof | 祐和医药科技(北京)有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115536748-A | Monoclonal antibody for neutralizing Taq DNA polymerase polymerization activity and application thereof | 深圳华大生命科学研究院 | 2022-12-30 | — | — | CN | disclosed |
| CN-115551543-A | Method | 奥托路斯有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115551594-A | Cytokine-modified chimeric antibodies and methods of use thereof | 米诺陶治疗公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115551537-A | Tumor cell vaccine | 纽沃进公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115551884-A | Recombinant microalgae producing KTTKS peptides, polypeptides or proteins and their derivatives, and methods and uses related thereto | 赛德玛公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115551544-A | Cells | 奥托路斯有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115536749-A | Trispecific antibodies, methods of making and uses thereof | 三生国健药业（上海）股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115521917-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-115521942-A | BVDV epitope gene vaccine construction method and application thereof | 天津市农业科学院 | 2022-12-27 | — | — | CN | disclosed |
| CN-110678484-B | anti-PD-L1/anti-LAG 3 bispecific antibody and application thereof | 天境生物科技(杭州)有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-108472348-B | Attenuated bacteria for the treatment of malignant solid tumors | 巴塞尔大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-108866092-B | Production of herbicide-resistant genes and uses thereof | 中国科学院遗传与发育生物学研究所 | 2022-12-27 | — | — | CN | disclosed |
| CN-112646044-B | TFF2-Fc fusion protein and high-efficiency expression production method thereof | 山东睿鹰制药集团有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-114269389-B | Antibody drug conjugates targeting claudin 18.2 | 礼新医药科技(上海)有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-109593069-B | Method for synthesizing 4-substituted oxazolidinone compound through biocatalysis | 遵义医学院 | 2022-12-23 | — | — | CN | disclosed |
| CN-115515633-A | Administration and administration of activatable anti-CTLA-4 antibodies | 百时美施贵宝公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-113307870-B | anti-IL 5 nano antibody and application thereof | 上海洛启生物医药技术有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-113336837-B | Polypeptide and application thereof in preparing anti-neurodegenerative disease medicine | 中国药科大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-115505042-A | Monoclonal anti-IL-1 RACP antibodies | 赛诺菲生物技术公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-109415442-B | Humanized anti-IL-1R 3 antibodies | 赛诺菲生物技术公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115515628-A | Mumps and measles virus immunogens and uses thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2022-12-23 | — | — | CN | disclosed |
| CN-115515616-A | Ulinastatin polypeptide | 代阿麦迪卡美国股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115505045-A | Novel bispecific antibody targeting LAG-3 and PD-L1 and application thereof | 迈威(上海)生物科技股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-107847568-B | anti-CLL-1 antibodies and methods of use | 豪夫迈·罗氏有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-115491381-A | Rice copper stress response gene OsCORK1 and encoding protein and application thereof | 河南农业大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113337486-B | Recombinant microorganism and preparation method and application thereof | 廊坊梅花生物技术开发有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-109152835-B | Bispecific binding proteins and uses thereof | 免疫医疗有限责任公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-115475234-A | Application of plant JAZ protein and derivative polypeptide in preventing and treating human and animal tumors | 中国农业科学院棉花研究所 | 2022-12-16 | — | — | CN | disclosed |
| CN-115485031-A | Methods and compositions | 鳄鱼生物科学公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115485299-A | PD-1 agonist multimeric binding molecules | IGM生物科学股份有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-112399973-B | Dimers and uses thereof | 江苏康宁杰瑞生物制药有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115485559-A | Biomarkers predictive of response to checkpoint inhibitors | 中外制药株式会社 | 2022-12-16 | — | — | CN | disclosed |
| CN-115478041-A | Construction and application of engineering bacteria for efficiently synthesizing 5-methylpyrazine-2-carboxylic acid | 山东新时代药业有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115485289-A | Methods and compositions for gene delivery using engineered viral particles | 宾夕法尼亚大学董事会 | 2022-12-16 | — | — | CN | disclosed |
| CN-115478061-A | Cellulase mutants and compositions thereof | 宜昌东阳光药业股份有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115485552-A | Method for detecting an analyte in a medium containing light-scattering components | 伦敦国王学院 | 2022-12-16 | — | — | CN | disclosed |
| CN-115484980-A | Pharmaceutical formulations | 安进公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115485561-A | Predicting response to PD-1 axis inhibitors | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115485028-A | Immunoconjugates | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113527448-B | Application of protein in preventing and treating Spodoptera frugiperda and/or cotton bollworm | 中国农业科学院植物保护研究所 | 2022-12-16 | — | — | CN | disclosed |
| WO-2022257831-A1 | POLYPEPTIDE COMPOUNDS USING PD-1 RECEPTORS AS TARGETS, PREPARATION METHOD THEREFOR AND USE THEREOF | 南通大学 | 2022-12-15 | — | — | WO | disclosed |
| CN-113186238-B | 4,6-alpha-glucosyltransferase and application thereof in improving steamed bun quality | 江南大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-112575041-B | Engineering bacterium for producing PHB (polyhydroxybutyrate) by high-efficiency fermentation of mixed carbon source and application of engineering bacterium | 江南大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-111057146-B | Antibodies specific for enteroviruses that infect humans | MAB探索私人有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-110157746-B | Method for synthesizing auxin by microorganisms | 赣南师范大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-112608930-B | Application of BnaSVP gene in regulation of flowering phase of rape and preparation method of rape mutant material with different flowering phases | 华中农业大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-114729016-B | Enzyme mutant for producing 3-aminoisobutyric acid | 南京纽邦生物科技有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-115466331-A | BCMA-targeted chimeric antigen receptor and application thereof | 合源生物科技(天津)有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-111020039-B | Campylobacter jejuni species specific molecular target and rapid detection method thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2022-12-09 | — | — | CN | disclosed |
| CN-115461065-A | Compositions comprising probiotics for expression and secretion of Enterocin to control clostridium perfringens-induced necrotic enteritis in livestock and related methods | 普通益生菌股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115461362-A | Cancer combination therapy based on ICOS antibody and PD-L1 antibody TGF-beta receptor fusion protein | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115461080-A | Pharmaceutical formulations | 安进公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115449521-A | Binary vector for simultaneously expressing insect-resistant gene and herbicide-resistant gene and application thereof | 杭州芳韵生物科技有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115461460-A | Compositions and methods for inhibiting expression of transthyretin (TTR) | 阿尔尼拉姆医药品有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-115461082-A | Compositions and methods for treating hereditary macular degeneration | 萨利欧基因治疗公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-114540325-B | Method for targeted DNA demethylation, fusion protein and application thereof | 广州医科大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-112041448-B | Constructs and methods related to agronomic trait altered plants and abiotic stress tolerance genes under nitrogen limiting conditions | 未名生物农业集团有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-112725298-B | Machine learning gene mining method and glufosinate-ammonium dehydrogenase mutant for amino transposition | 浙江工业大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-115443151-A | anti-CD 137 antigen binding molecules for cancer therapy | 中外制药株式会社 | 2022-12-06 | — | — | CN | disclosed |
| CN-113214363-B | A group of special dietary proteins | 湖北康肽药业有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-113278053-B | A group of special dietary proteins | 湖北康肽药业有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115443140-A | Human ROR-1 antibodies and anti-ROR-1-CAR-T cells | 苏州恒康生命科学有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115433274-A | Nano antibody of targeted Human Serum Albumin (HSA) and application thereof | 北京科诺信诚科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-112105637-B | Nano antibody capable of combining SFTSV and application thereof | 源道隆（苏州）医学科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115433285-A | Coronavirus-targeting antibodies and uses thereof | 百奥泰生物制药股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-113264988-B | A group of special dietary proteins | 湖北康肽药业有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-115443291-A | Antibodies that bind CTLA4 and uses thereof | 博奥信生物技术（南京）有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-109251907-B | DNA polymerase with improved gene mutation specific amplification efficiency | 基因凯斯特有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-107109490-B | Analysis of polymers | 牛津楠路珀尔科技股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-109791131-B | LC/MS/MS analysis for meat species identification of raw and processed meat products | DH科技发展私人贸易有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-113444178-B | anti-CD 70 internalizing antibody, antibody conjugate and application thereof | 南京蓝盾生物科技有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115427435-A | Reconstituted silk solids and membranes | 保尔特纺织品公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-110402255-B | Novel bispecific antigen binding molecules capable of specifically binding to CD40 and FAP | 豪夫迈·罗氏有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115427440-A | Chimeric receptors for engineered cells | 圭尔医疗有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-108368491-B | Algal mutants with improved lipid productivity | 合成基因组股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115427071-A | Compositions comprising LTB and pathogenic antigens and uses thereof | 米加尔加利利研究所有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115427433-A | Protective staphylococcal exotoxin vaccine | 生物医学研究及生物制品公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115427451-A | Immune cell overexpressing externally introduced cell signal regulatory factor and use thereof | 北京永泰瑞科生物科技有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-20220380414-A1 | COMPOSITIONS AND METHODS BASED ON HIV GP120 MUTANTS | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. | 2022-12-01 | — | — | US | disclosed |
| CN-110904121-B | Application of susceptibility gene SR30 in improving crop resistance | 南京农业大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-107690482-B | Modified microorganism for optimized production of 2,4-dihydroxybutyric acid | 代谢探索者公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-109071480-B | Solid forms of (-) -ambrox formed by bioconversion of homofarnesol in the presence of a biocatalyst | 奇华顿股份有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-111321122-B | Duck egg laying-reduction syndrome virus and vaccine thereof | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 2022-11-29 | — | — | CN | disclosed |
| CN-114606215-B | Argonaute protein derived from eukaryote and application thereof | 湖北大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-115397463-A | Vaccine against African swine fever virus infection | 皮尔布莱特研究所 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397838-A | Compositions and methods of use of oncolytic virus-like vesicles | 卡罗根公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397866-A | DLL 3-targeted multispecific antigen-binding molecules and uses thereof | 中外制药株式会社 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397861-A | Combination therapy for cancer | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112538116-B | Group of 4-1BB monoclonal antibodies and medical application thereof | 东大生物技术(苏州)有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-111808838-B | Cinnamomum camphora linalool synthetase, molecular marker for identifying linalool type camphor tree and application of linalool type camphor tree molecular marker | 江西省林业科学院 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397459-A | Method for inducing new epitope-specific T cells using PD-1 axis binding antagonists and RNA vaccines | 基因泰克公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397448-A | Delivery of sialidases to cancer cells, immune cells and tumor microenvironment | 安迅生物制药公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397515-A | Human anti-CD 33 antibodies and uses thereof | 弗莱德哈钦森癌症中心 | 2022-11-25 | — | — | CN | disclosed |
| CN-115398546-A | Improved method for in vitro transcription of messenger RNA | 翻译生物公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397853-A | Antibody with specificity to CD47 and PD-L1 and application thereof | 辉瑞大药厂 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397855-A | Claudin-6 targeted multispecific antigen binding molecules and uses thereof | 中外制药株式会社 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397992-A | Collagenase and use thereof | 天野酶制品株式会社 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397854-A | anti-NKp 30 antibodies and methods of use | 百济神州有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115397461-A | Chimeric antigen receptor with CD28 mutation and application thereof | 纪念斯隆-凯特琳癌症中心 | 2022-11-25 | — | — | CN | disclosed |
| US-20220372108-A1 | PDL1 PEPTIDES FOR USE IN CANCER VACCINES | IO BIOTECH APS (DK) | 2022-11-24 | — | — | US | disclosed |
| CN-115380050-A | Antigen binding molecules to ALPPL2 and/or ALPP and uses thereof | 新加坡科技研究局 | 2022-11-22 | — | — | CN | disclosed |
| CN-113735282-B | Old yellow enzyme OYE2 protein and application thereof in chromium pollution | 江南大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-115380049-A | Treatment of physiological iron overload | 凯玛布有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-111182944-B | Bispecific 2+1 Contorsbody | 豪夫迈·罗氏有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-113549631-B | Blue grain character major gene of wild one-grain wheat and molecular marker and application thereof | 四川农业大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-114574500-B | Clone and application of rice sword-leaf sheath and panicle whitening trait gene OsWSSP | 中国农业科学院深圳农业基因组研究所 | 2022-11-22 | — | — | CN | disclosed |
| CN-112881692-B | Protein quantitative detection method for early screening of colorectal cancer and adenoma | 深圳华大基因股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-115380047-A | CD28 Single Domain antibodies and multivalent and multispecific constructs thereof | 印希比股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-115380109-A | D-psicose 3-epimerase for bioconverting D-fructose into D-psicose | 康纳根有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-109121420-B | Cold-resistant plant | KWS种子欧洲股份公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-115380111-A | Compositions, systems, and methods for base diversification | 成对植物服务股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-115361967-A | Cyclic peptides from the C-terminal end of acetylcholinesterase for the treatment of skin disorders and for cosmetic use | 神经生物有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115362175-A | anti-ACVR 1 antibodies and uses thereof | 瑞泽恩制药公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-110719732-B | Transgenic silkworms expressing spider silk | 犹他州立大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-115362260-A | Systems and methods for highly productive recombinant microorganisms and uses thereof | 克莱拉食品公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115361955-A | Chimeric antigen receptor T cell compositions against BCMA and methods and uses thereof | 朱诺治疗学股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-109251965-B | PCR buffer composition for enhancing DNA polymerase activity with increased gene mutation specificity | 基因凯斯特有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115362174-A | Bispecific antibodies comprising modified C-terminal crossfab fragments | 豪夫迈·罗氏有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115362259-A | Method for producing mixture of copolymerized polyhydroxyalkanoate, and transformed microorganism | 株式会社钟化 | 2022-11-18 | — | — | CN | disclosed |
| CN-115362177-A | Purification of saccharides | 辉瑞公司 | 2022-11-18 | — | — | CN | disclosed |
| US-20220364130-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-11-17 | — | — | US | disclosed |
| US-20220365101-A1 | METABOLITE BIOMARKERS FOR DISEASES ASSOCIATED WITH THE CONTACT ACTIVATION SYSTEM | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-11-17 | — | — | US | disclosed |
| CN-115340604-A | TIM-3 fully human monoclonal antibody and application thereof | 苏州博奥明赛生物制药有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-107708733-B | Anti-sortilin antibodies and methods of use thereof | 艾利妥 | 2022-11-15 | — | — | CN | disclosed |
| CN-111196855-B | anti-EGFR/PD-1 bispecific antibodies | 三生国健药业（上海）股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-112920959-B | Method for increasing yield of L-menthol in saccharomycetes | 江南大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-114196655-B | Heat-resistant Kunmu polysaccharide degrading enzyme OUC-SaLam66 and application thereof | 中国海洋大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-115335370-A | Fibroblast activation protein ligands for targeted delivery applications | 菲洛谢姆股份公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115322248-A | Potassium ion channel protein AlAKT1, coding gene thereof and application thereof | 大连理工大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-115335120-A | Method for inhibiting MASP-2 for the treatment and/or prevention of coronavirus induced acute respiratory distress syndrome | 奥默罗斯公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115335397-A | HBV-specific TCR libraries and their use as personalized medicine | 来恩生物医药私人有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115335087-A | Compositions and methods for reducing transplant rejection in allogeneic cell therapy | 南京传奇生物科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-106414755-B | Microbial pathway for the production of 5-hydroxytryptophan | 生物技术时代公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115317600-A | Foot and mouth disease vaccine | 硕腾服务有限责任公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115335530-A | Submerged fermentation method | 诺维信公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115335410-A | Method for producing multispecific antigen-binding molecules | 中外制药株式会社 | 2022-11-11 | — | — | CN | disclosed |
| CN-115334910-A | Materials and methods for protein production | 非凡食品有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115335525-A | Modified channelrhodopsins | 国立大学法人岩手大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-115335526-A | Ribozyme-mediated RNA assembly and expression | 罗切斯特大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-114250205-B | 7 alpha-hydroxysteroid dehydrogenase mutant with high thermal stability and application thereof | 宋建芳 | 2022-11-11 | — | — | CN | disclosed |
| CN-110669135-B | Bispecific antibody and application thereof | 上海健信生物医药科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-113307866-B | Antibody composition and application thereof | 中山大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-115322257-A | BCMA (brain cell adhesion antigen) targeted antibody, chimeric antigen receptor and application thereof | 上海优替济生生物医药有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-114591425-B | Specific antibody of new coronavirus S protein RBD region and preparation method and application thereof | 生物岛实验室 | 2022-11-11 | — | — | CN | disclosed |
| CN-109844117-B | Monophosphoryl lipid a-producing bacterium and method for producing monophosphoryl lipid a using bacterium | 韩国科学技术研究院 | 2022-11-11 | — | — | CN | disclosed |
| CN-112940130-B | Binding protein capable of specifically binding to MPO, use thereof, reagent, kit and method for detecting MPO | 菲鹏生物股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115315256-A | Methods of treating cancer with anti-TIGIT antagonist antibodies | 基因泰克公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115315527-A | Methods of treatment for subjects with at risk alleles in IL33 | 免疫医疗有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115315444-A | Use of an anti-IL-6 antibody, such as Clazazumab, for treating/preventing ARDS associated with coronavirus (COVID-19) infection | 维塔里斯股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115315443-A | anti-SARS-COV-2 antibodies and uses thereof | 腾盛华创医药技术(北京)有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-113430186-B | Fructokinase from fungus traditional Chinese medicine and coding gene and application thereof | 北京中医药大学深圳医院(龙岗)(深圳市龙岗区中医院) | 2022-11-08 | — | — | CN | disclosed |
| CN-112979799-B | Binding protein containing hemoglobin antigen structural domain | 东莞市朋志生物科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-108350055-B | Compositions and methods for adjoining type I and type II extracellular domains as heterologous chimeric proteins | 热生物制品有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115304678-A | Bifunctional nano antibody based on DC cell and construction method and application thereof | 江苏省农业科学院 | 2022-11-08 | — | — | CN | disclosed |
| CN-109890972-B | Method for producing target substance | 味之素株式会社 | 2022-11-08 | — | — | CN | disclosed |
| CN-111150833-B | Application of LTX-315 in preparation of product for inhibiting coronavirus | 中国科学院微生物研究所 | 2022-11-08 | — | — | CN | disclosed |
| CN-115304672-A | Coronavirus antibody and application thereof | 百奥泰生物制药股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115315272-A | Targeting difunctional degradation agent | 耶鲁大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-111406067-B | Binding agents that bind to PD-L1 and CD137 and uses thereof | 健玛保 | 2022-11-08 | — | — | CN | disclosed |
| CN-113481139-B | Recombinant bacillus subtilis for producing glycocyamine and construction method thereof | 江南大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-115315447-A | Immune-activated multispecific antigen-binding molecules and uses thereof | 中外制药株式会社 | 2022-11-08 | — | — | CN | disclosed |
| CN-110592050-B | Bifunctional enzyme for degrading heparan sulfate and hyaluronic acid and application thereof | 南通大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-111018991-B | anti-CA50 antibody and application thereof | 东莞市朋志生物科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115298217-A | NKG2D, CD and FLT3 binding protein | 蜻蜓疗法股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115297874-A | Immune cell delivery of sialidases to cancer cells, immune cells and tumor microenvironment | 安迅生物制药公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-113412818-B | Non-human animal having humanized cluster of differentiation 274 gene | 瑞泽恩制药公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-112574304-B | Antibody for resisting C-reactive protein | 东莞市朋志生物科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-109666973-B | Peptide library crossing blood brain barrier and screening method thereof | 北京大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-113039208-B | anti-PD-L1 antigen binding protein and application thereof | 和铂医药(上海)有限责任公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115298221-A | Antibodies that bind B7H4 | 健玛保 | 2022-11-04 | — | — | CN | disclosed |
| CN-115298328-A | Methods for determining responsiveness to IL-10 treatment using genetic markers, SNPs, and/or INDELs | 德卡生物科学公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115261353-A | DNA polymerase with adjustable pyrophosphorylase activity and preparation method thereof | 厦门通灵生物医药科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279716-A | Discovery and evolution of bioactive metabolites | 科罗拉多州立大学董事会（法人团体） | 2022-11-01 | — | — | CN | disclosed |
| CN-115279381-A | BCMA directed cellular immunotherapy compositions and methods | 恩卡尔塔公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279794-A | Expression of sequence engineered lambda antibody light chains | 科马布有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115261366-A | High-temperature-resistant cellobiose epimerase mutant, engineering bacterium and application thereof | 浙江工业大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279890-A | Genetically modified microorganism for producing 3-hydroxyadipic acid and/or alpha-hydrogenated adipic acid and method for producing the same | 东丽株式会社 | 2022-11-01 | — | — | CN | disclosed |
| CN-107001431-B | Bacteria-based protein delivery | 巴塞尔大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-112592958-B | Method for detecting D-2-hydroxyglutarate by using FAD-dependent D-2-hydroxyglutarate dehydrogenase and resazurin | 山东大学第二医院 | 2022-11-01 | — | — | CN | disclosed |
| CN-112852821-B | CD81 aptamer and application thereof | 苏州吉玛基因股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-109486837-B | High-temperature biological desulfurization genes and application | 南开大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107922496-B | IL2 Rbeta/Universal gamma chain antibodies | 新加坡科技研究局 | 2022-11-01 | — | — | CN | disclosed |
| CN-115261351-A | Reverse transcription-polymerization bifunctional enzyme, preparation method and application thereof | 厦门通灵生物医药科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279407-A | Targeting module comprising PD-L1 and/or PD-L2 for use in a method of stimulating a chimeric antigen receptor mediated immune response in a mammal | 阿文塞勒欧洲有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-111051350-B | Immunoconjugates comprising signal-modulating protein alpha | 苏州丁孚靶点生物技术有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114573704-B | PD-1/CTLA-4 binding protein and medical application thereof | 北京拓界生物医药科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-108610418-B | Anti-complement C1s antibodies and uses thereof | 美国比奥维拉迪维股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279418-A | Compositions, methods and uses of messenger RNA | 川斯勒佰尔公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279419-A | Compositions and methods for genome engineering | 美商圣加莫治疗股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279789-A | Antibodies that disrupt the interaction of GAL3 and insulin receptor or integrin and methods of use thereof | 真和制药有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115261367-A | Cellobiose epimerase mutant and application thereof | 浙江工业大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-115279406-A | Formulations of protein therapeutics | 阿帕特夫研究和发展有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115245144-A | Kit for preparing pig rich in omega-3fatty acid and preparation method and application thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-109575120-B | TCR for identifying PRAME antigen short peptide and coding sequence thereof | 香雪生命科学技术（广东）有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-112480262-B | Fusion protein and preparation and application thereof | 中国科学院沈阳应用生态研究所 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247174-A | Gene editing system for constructing congenital gamma globulin deficiency model pig nuclear transplantation donor cell and application thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247186-A | Gene editing system for constructing AF double-gene mutant atherosclerosis model pig nuclear transplantation donor cells and application thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247185-A | Application of OsAPL protein and coding gene thereof in regulation and control of plant yield | 中国科学院植物研究所 | 2022-10-28 | — | — | CN | disclosed |
| CN-115248317-A | Antigen of soybean allergy | 朋友股份有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247165-A | Cellulase mutant with improved specific activity and thermal stability | 宜昌东阳光生化制药有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247175-A | Gene editing system for constructing epigenetic dysregulation model pig nuclear transplantation donor cell of SETDB1 gene mutation and application thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247180-A | Kit and application thereof in construction of recombinant pig cells of hair follicle tissue specific expression human II type 5 alpha-reductase gene | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247164-A | Gene editing system for constructing adenomatous polyposis model pig and colorectal cancer model pig and application thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247181-A | Kit for preparing nuclear transplantation donor cells of alopecia model pigs and preparation method thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-109997041-B | Human leukocyte antigen-restricted gamma delta T cell receptors and methods of use thereof | 歌德塔有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-107743524-B | Method for prognosis of prostate cancer | 皇家飞利浦有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247153-A | Gene editing system for constructing diabetes model pig nuclear transplantation donor cells with HNF1A gene mutation and application thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247166-A | Protease mutant | 南京百斯杰生物工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247173-A | Gene editing system for constructing TMPRSS6 gene mutant iron deficiency anemia pig nuclear transplantation donor cells and application thereof | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115247191-A | Gene editing system and application thereof in construction of double-gene-mutation nevus basal cell carcinoma syndrome pig nuclear transplantation donor cell | 南京启真基因工程有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-110423738-B | Method for separating and purifying beta-glucosidase fusion protein | 江苏大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-111234036-B | African swine fever virus p72 fusion protein and preparation method and application thereof | 天康制药(苏州)有限公司 | 2022-10-28 | — | — | CN | disclosed |
| US-20220340947-A1 | PROKARYOTE-BASED CELL-FREE SYSTEM FOR THE SYNTHESIS OF GLYCOPROTEINS | UNIV CORNELL (US) | 2022-10-27 | — | — | US | disclosed |
| US-20220340852-A1 | CELL CULTURE SHEET AND LARGE-CAPACITY CELL CULTURE DEVICE INCLUDING SAME | AMOLIFESCIENCE CO., LTD. (KR) | 2022-10-27 | — | — | US | disclosed |
| US-20220340662-A1 | COMBINATION OF MASKED CTLA4 AND PD1/PDL1 ANTIBODIES FOR TREATING CANCER | Xilio Development, Inc. | 2022-10-27 | — | — | US | disclosed |
| CN-115244080-A | anti-Adrenomedullin (ADM) antibody or anti-ADM antibody fragment or anti-ADM non-Ig scaffold for the treatment or prevention of shock | 艾德里诺医药公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232817-A | Gene editing system for constructing three-gene combined mutant miniature pig nuclear transplantation donor cells and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-109486803-B | Engineered phenylalanine ammonia lyase polypeptides | 科德克希思公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112481245-B | Recombinant D-tagatose 3 epimerase DTE-CM and construction method and application thereof | 江苏大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-114214398-B | Mutant FBN1 gene and marfan syndrome detection kit | 百世诺(北京)医学检验实验室有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232836-A | Gene editing system for constructing congenital cataract model pig nuclear transplantation donor cell with CRYGC gene mutation and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232793-A | Gene editing system for constructing ALS model pig nuclear transplantation donor cells with SOD1 gene mutation and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232815-A | Gene editing system for constructing MIP gene mutation cataract disease model pig nuclear transplantation donor cell and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115244182-A | Enhanced expression yield of immunoglobulin a in eukaryotes | 文特里亚生物科学公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232794-A | Gene editing system and application thereof in construction of OCA-1B albinism model pig nuclear transplantation donor cells | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232814-A | Method and system for constructing congenital cataract disease model pig nuclear transplantation donor cells with CRYBB2 gene mutation | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115244401-A | DPP3 for therapy guidance, monitoring and stratification of NT-ADM antibodies in shock patients | 4TEEN4制药有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232802-A | Beta-glucosidase mutant, engineering bacteria and application thereof | 浙江工业大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232816-A | CRISPR system for constructing cataract model pig nuclear transplantation donor cells with YAP1 gene mutation and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115243713-A | Methods and compositions for delivering modified lymphocyte aggregates | 埃克苏马生物技术公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115244071-A | Multifunctional multispecific polymer biomolecule polymer for prolonging duration in organism | 株式会社原真生物技术 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232812-A | Method for constructing nuclear transplantation donor cells of MRAP2 gene mutation severe early obesity model pigs | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232797-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115244177-A | High fidelity SpCas9 nuclease for genome modification | 西格马-奥尔德里奇有限责任公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112480265-B | GNRH-I6 virus-like particle subunit vaccine | 深圳赫兹生命科学技术有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-113293148-B | Construction of H gene replaced chimeric measles attenuated strain | 上海青赛生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112830968-B | anti-VEGF single domain antibody, humanization thereof, fusion protein constructed by single domain antibody and IgG1-Fc and application | 北京纽安博生物技术有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112813040-B | Old yellow enzyme OYE1 mutant protein and application thereof in enzyme-catalyzed asymmetric reduction of 2-aryl acrylic acid derivatives | 沈阳药科大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-110951893-B | Molecular marker related to intramuscular fat and detection method of intramuscular fat content | 中国农业科学院北京畜牧兽医研究所 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232811-A | Method for constructing HBB gene mutant sickle cell anemia model pig nuclear transplantation donor cell and application | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232834-A | Gene editing system for constructing nuclear transplantation donor cells of OCA-1A albinism model pigs and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232813-A | Gene editing system for constructing von willebrand model pig nuclear transplantation donor cells with vWF gene mutation and application of gene editing system | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232818-A | Gene editing system for constructing congenital myasthenia model pig nuclear transplantation donor cells with DOK7 gene mutation and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232796-A | Gene editing system for constructing central precocity model pig nuclear transplantation donor cells with MKRN3 gene mutation and application thereof | 南京启真基因工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115243762-A | anti-TMPRSS6 antibodies and uses thereof | 迈威(美国)生物治疗有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-111349621-B | Recombinant baculovirus and application thereof in preparation of newcastle disease virus-like particles | 青岛易邦生物工程有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115216455-A | Application of ENB1 gene and encoding protein thereof in regulation and control of plant grain size and grain weight | 中国农业大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-107987156-B | TCR for recognizing SAGE1 antigen short peptide | 中国科学院广州生物医药与健康研究院 | 2022-10-21 | — | — | CN | disclosed |
| CN-114591400-B | Group of targeted FoxM1-DBD polypeptides and application thereof | 西南交通大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-113603777-B | IL17 antibodies and uses thereof | 原启生物科技(上海)有限责任公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112679587-B | Recombinant antigen protein easy to activate B cells and preparation method thereof | 龙湖现代免疫实验室 | 2022-10-21 | — | — | CN | disclosed |
| CN-115216488-A | Method for creating large-long-grain type new rice germplasm or large-long-grain type short-stalk new rice germplasm and application thereof | 中国种子集团有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112724223-B | Preparation and application of monoclonal antibody of spore wall protein of nosema enteromorpha | 华南农业大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-109929889-B | Preparation method of L-tyrosine | 安徽华恒生物科技股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-113603776-B | IL17 antibodies and uses thereof | 原启生物科技(上海)有限责任公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-115216456-A | Thermophilic nucleoside kinase mutant and application thereof | 华东理工大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-115216449-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-115212309-A | Method, application and medicament for preventing cancer recurrence and inhibiting or reversing inflammation and canceration of normal tissues | 清华大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-113101368-B | Application of SLC7A8 in auxiliary diagnosis, precancerous early warning and targeted therapy of esophageal squamous cell carcinoma | 中国医学科学院肿瘤医院 | 2022-10-21 | — | — | CN | disclosed |
| CN-110684102-B | SFTSV detection kit | 源道隆（苏州）医学科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112206310-B | Parasitic tapeworm polypeptides for inhibiting complement | 湖北医药学院 | 2022-10-21 | — | — | CN | disclosed |
| EP-3334343-B1 | EVACUATED BLOOD COLLECTION TUBES CONTAINING PROTEASE INHIBITORS FOR THE ASSESSMENT OF CONTACT SYSTEM ACTIVATION | TAKEDA PHARMACEUTICALS CO (JP) | 2022-10-19 | — | — | EP | disclosed |
| CN-109071640-B | Modified anti-tenascin antibodies and methods of use | 豪夫迈·罗氏有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114410650-B | Rice salt sensitive mutant gene SS2, mutant SS2 and application | 广东省农业科学院农业质量标准与监测技术研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-115210371-A | Carbohydrate binding module variants | 诺维信公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-112175849-B | Recombinant yeast with improved L-menthol yield | 江南大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-112921021-B | Aldolase mutant and application thereof in production of 1,3-propanediol | 北京化工大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-110577947-B | Beta-glucosidase mutant and application thereof | 广西师范大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-109563528-B | MBTH-like protein in eukaryotic NRPS catalytic process | 灿盛制药荷兰公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-112851789-B | Brain-targeted HIV entry inhibitor polypeptide and application thereof | 大理大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-108135976-B | Compounds targeting IL-23A and B cell activating factor (BAFF) and uses thereof | 博灵格英格尔海姆国际股份公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115197974-A | Method for improving conversion efficiency of biological butanol | 广州市乾相生物科技有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-107106590-B | Combination (I) | 阿斯利康(瑞典)有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115209909-A | Delivery compositions and methods | 伊迪生物治疗公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115209916-A | Vaccines and methods for detecting and preventing filariasis | 伊利诺伊大学理事会 | 2022-10-18 | — | — | CN | disclosed |
| CN-115210258-A | Antibody for specifically recognizing thymic stromal lymphopoietin and application thereof | 舒泰神（北京）生物制药股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115210379-A | Modified transglutaminase | 天野酶制品株式会社 | 2022-10-18 | — | — | CN | disclosed |
| CN-109790213-B | Methods for identifying LILRB blocking antibodies | 德克萨斯大学体系董事会 | 2022-10-18 | — | — | CN | disclosed |
| CN-108779474-B | FMDV vaccine using recombinant adenovirus as vector and application thereof | 勃林格殷格翰动物保健美国公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115197941-A | RNA with molecular chaperone function and application thereof | 中国科学院分子细胞科学卓越创新中心 | 2022-10-18 | — | — | CN | disclosed |
| CN-109942705-B | MSTN nano antibody, construction method and application thereof | 石河子大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-115210265-A | Protease-processed molecules | 赛诺菲 | 2022-10-18 | — | — | CN | disclosed |
| CN-113308426-B | Recombinant corynebacterium for modifying TK gene 5' terminal sequence and application thereof | 齐鲁工业大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-115209920-A | Thienoazepine immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115210256-A | Novel methods and compounds for prostate cancer diagnosis | 瑞典普洛医疗公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-108883191-B | Antibody-conjugates with improved therapeutic index for targeting CD30 tumors and methods for improving the therapeutic index of antibody-conjugates | 西纳福克斯股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-111808874-B | Encoding gene of phosphotriesterase 8047-PTE and application thereof | 中国科学院微生物研究所 | 2022-10-14 | — | — | CN | disclosed |
| CN-115181167-A | Screening method of ethanol production strain based on Bmor mutant | 北京理工大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-115181169-A | Method for improving adhesion of recombinant mussel protein | 南京工业大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-109652400-B | Molecular modification method of half-life period of anti-cancer drug arginine deiminase and mutant strain | 中国科学院天津工业生物技术研究所 | 2022-10-14 | — | — | CN | disclosed |
| CN-115181168-A | Ethanol-insensitive n-butanol specific response Bmor protein mutant | 北京理工大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-115177722-A | Recombinant cholinesterase preparation and application thereof | 上海桀蒙生物技术有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-115177728-A | Method for treating cancer caused by MAPK/ERK pathway activation, application of cancer and CREPT-CDK9 complex | 清华大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-109069658-B | Antibody-conjugates with improved therapeutic index for targeting HER2 tumors and methods for improving the therapeutic index of antibody-conjugates | 西纳福克斯股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-115190804-A | Compositions and methods for stabilizing targeted proteins by redirecting endogenous deubiquitinating enzymes | 纽约市哥伦比亚大学理事会 | 2022-10-14 | — | — | CN | disclosed |
| WO-2022215843-A1 | METHOD FOR PREDICTING THERAPEUTIC RESPONSE OF CANCER PATIENT TO ANTICANCER IMMUNOTHERAPY USING NATURAL KILLER CELLS | (주)에스엠티바이오 | 2022-10-13 | — | — | WO | disclosed |
| CN-110305220-B | Cancer-targeted enhanced anti-tumor fusion protein and preparation method and application thereof | 孙嘉琳 | 2022-10-11 | — | — | CN | disclosed |
| CN-112458086-B | Construction method and application of Hspg2 gene knock-in mouse animal model | 中国人民解放军总医院第一医学中心 | 2022-10-11 | — | — | CN | disclosed |
| CN-115175939-A | anti-PD-L1 antibodies | 博尔特生物治疗药物有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115175697-A | Group A streptococcus immunogenic compositions with polysaccharide-protein conjugates | VAXCYTE公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-111138546-B | Homodimer type bispecific antibody and preparation method and application thereof | 安源医药科技（上海）有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115175981-A | Cell culture substrate and preparation method thereof | 阿莫生命科学有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115176019-A | Recombinant microalgae capable of producing peptides, polypeptides or proteins of collagen, elastin and derivatives thereof in the chloroplasts of the microalgae and methods relating thereto | 藻类和细胞公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115175929-A | BCMA CAR-T cells with enhanced activity | 艾洛基治疗公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-113151345-B | Method for creating new germplasm of rice with low gelatinization temperature and application thereof | 中国种子集团有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115176020-A | Cells, tissues, organs and/or animals with one or more modified genes for enhancing xenograft survival and/or tolerance | E开创生物技术股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115175928-A | Novel mesothelin-specific Chimeric Antigen Receptor (CAR) for solid tumor cancer immunotherapy | 塞勒克提斯公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115154419-A | Nano micelle precursor, nano micelle, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-10-11 | — | — | CN | disclosed |
| CN-115161336-A | Pichia pastoris strain and application thereof in production of mannanase | 青岛蔚蓝生物集团有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-115160415-A | Bmor protein mutant specifically responding to n-butanol and application thereof | 北京理工大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-115161301-A | High-specificity Taq DNA polymerase variant and application thereof | 山东大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-115160418-A | Pichia capsulata Peptidase secretory protein and application thereof | 西南大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-115160419-A | Pichia pastoris Thioredoxin secretory protein and application thereof | 西南大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-115161325-A | Construction method and application of riboflavin reaction exercise intolerance mouse model | 广州市妇女儿童医疗中心 | 2022-10-11 | — | — | CN | disclosed |
| CN-115160417-A | Pichia anomala Glyco _ hydro secretory protein and application thereof | 西南大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-115161302-A | High-specificity Taq DNA polymerase variant and obtaining method and application thereof | 山东大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-108865913-B | Method for constructing recombinant bacterium capable of efficiently secreting and expressing chondroitin sulfate hydrolase | 江南大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-110305221-B | Enhanced anti-tumor fusion protein, preparation method and application | 孙嘉琳 | 2022-10-11 | — | — | CN | disclosed |
| CN-115175736-A | Hybrid antibodies | 艾普西洛根有限公司 | 2022-10-11 | — | — | CN | disclosed |
| US-11464824-B2 | Peptide capable of improving cognitive function | THE FOOD SCIENCE INSTITUTE FOUNDATION (JP) | 2022-10-11 | — | — | US | disclosed |
| US-11464790-B2 | Triterpenoids with HIV maturation inhibitory activity | ViiV Healthcare UK (No.4) Limited (GB) | 2022-10-11 | — | — | US | disclosed |
| CN-109970865-B | CD137 bidirectional activation costimulatory molecule receptor and application thereof | 上海细胞治疗研究院 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151258-A | Combination cancer therapy using PD-1 antagonists, ILT4 antagonists and lenvatinib or a salt | 默沙东有限责任公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151279-A | Cytokine-based bioactivatable agents and methods of use thereof | 科优基因公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115141806-A | Chimeric antigen receptor T cell targeting Her2 and expressing PD-L1 antibody, and preparation method and application thereof | 深圳宾德生物技术有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114736890-B | Application of rice chitinase and coding gene thereof in enhancing abiotic stress resistance of plants | 中国农业科学院作物科学研究所 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151569-A | CD163 antibodies or binding proteins | 埃科动物健康有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115141787-A | Submarine microbial sensor and preparation method and application thereof | 青岛农业大学 | 2022-10-04 | — | — | CN | disclosed |
| US-11458477-B2 | Evacuated blood collection tubes containing protease inhibitors for the assessment of contact system activation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| CN-115151636-A | Engineered erythroid cells comprising HLA-G polypeptides and methods of use thereof | 鲁比厄斯治疗法股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-108136012-B | Antigen binding constructs for targeting molecules | 伊麦吉纳博公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-112159769-B | Genetically engineered bacterium for producing L-menthol and construction method and application thereof | 江南大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151821-A | Method and reagent for detecting ovarian malignant tumor | 公立大学法人横滨市立大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151305-A | Anti- α v β 8 integrin antibodies for the treatment of kidney disease | 免疫医疗有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-113373127-B | Taq DNA polymerase mutant and application thereof | 中国农业科学院生物技术研究所 | 2022-10-04 | — | — | CN | disclosed |
| CN-115141280-A | Taq DNA polymerase monoclonal antibody and application thereof | 广东和信健康科技有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151559-A | Staphylococcal peptides and methods of use | 扬森疫苗与预防公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151308-A | anti-PD-L1 antibodies | 博尔特生物治疗药物有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115135302-A | IgG TGF beta RII fusion protein compositions | 阿雷斯贸易股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-115135344-A | Antibodies for use in therapy | 健玛保 | 2022-09-30 | — | — | CN | disclosed |
| CN-115135674-A | Dendritic cell activating chimeric antigen receptor and uses thereof | 深圳市珈钰生物科技有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-115124621-A | Nano antibody targeting PD-L1 and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-09-30 | — | — | CN | disclosed |
| CN-115135340-A | Vaccines against African swine fever virus and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2022-09-30 | — | — | CN | disclosed |
| CN-115135769-A | KDO-free production hosts for oligosaccharide synthesis | 因比奥斯公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-115128266-A | Methods and reagents for detecting autoantibodies | 欧蒙医学实验诊断股份公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-112638947-B | Chimeric antigen receptor cells for the treatment of solid tumors | 上海斯丹赛生物技术有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-115120716-A | Methods of treating cancer with PD-1 axis binding antagonists and RNA vaccines | 健泰科生物技术公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-115124627-A | MSLN-CAR-NK cell capable of autocrine IL2R beta gamma agonist and application thereof | 中国人民解放军海军军医大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-115125221-A | Mutant glucose dehydrogenase having improved thermostability and use thereof | 北卡罗来纳大学教堂山分校 | 2022-09-30 | — | — | CN | disclosed |
| CN-109970857-B | anti-PD-L1 antibodies and uses thereof | 信达生物制药(苏州)有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022203552-A1 | MONOCLONAL ANTIBODY THAT SPECIFICALLY BINDS TO GD2 | JOINT STOCK COMPANY "BIOCAD" (RU) | 2022-09-29 | — | — | WO | disclosed |
| CN-110195088-B | Arginine hydrolase, and coding gene and application thereof | 中国科学院分子植物科学卓越创新中心 | 2022-09-27 | — | — | CN | disclosed |
| CN-115109120-A | CD 8-specific capture agents, compositions and methods of use and preparation | 英蒂分子公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-111411099-B | Hemsleya amabilis acetyl transferase, coding gene thereof and application of hemsleya amabilis acetyl transferase in preparation of cucurbitacin | 云南农业大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-114702578-B | Novel coronavirus Omicron mutant strain specific antibody and application thereof | 百斯医学诊断科技(北京)有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-115109134-A | Application of alfalfa MsNRAMP2 protein in inhibition of tobacco mosaic virus | 哈尔滨师范大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-115109798-A | Improved CG base editing system | 上海蓝十字医学科学研究所 | 2022-09-27 | — | — | CN | disclosed |
| CN-115109766-A | High-temperature-resistant metalloprotease, and coding gene and application thereof | 上海理工大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-110234319-B | Compositions of benzamide and active compound and methods of use thereof | 转化药物开发有限责任公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114315982-B | Novel phage lysin LysDLn1 and application thereof | 暨南大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-115112889-A | Application of antigen combination in preparation of lung cancer detection reagent or kit | 基因科技（上海）股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-109196116-B | Method for characterizing target polynucleotide | 牛津纳米孔科技公开有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114806999-B | Genetically engineered bacterium and application thereof in preparing dihydrodaidzein | 华熙生物科技股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| US-11453715-B2 | Cellular factors involved in the cytotoxicity of Staphylococcus aureus leukocidins: novel therapeutic targets | NEW YORK UNIVERSITY (US) | 2022-09-27 | — | — | US | disclosed |
| CN-115119498-A | Tobacco mosaic virus-resistant tomato plant, method for producing tobacco mosaic virus-resistant tomato plant, method for imparting tobacco mosaic virus resistance to tomato plant, method for screening tobacco mosaic virus-resistant tomato plant, and method for detecting tobacco mosaic virus resistance of tomato plant | 国立研究开发法人农业·食品产业技术综合研究机构 | 2022-09-27 | — | — | CN | disclosed |
| CN-115112892-A | Method, application and kit for determining surgical incision margin of cancer | 清华大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-108699580-B | Heparan sulphate with a high 3-O-sulphation ratio in the glucosamine residue | 味之素株式会社 | 2022-09-23 | — | — | CN | disclosed |
| CN-112391389-B | Migratory locust C-type scavenger receptor gene and targeting dsRNA and application thereof | 山西大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-109234294-B | Method for synthesizing fatty alcohol acetate in microorganism based on fatty acyl-ACP | 赣南师范大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-115103852-A | PRAME TCR receptor and uses thereof | 德国生物新技术公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-115103856-A | HLA specific chimeric antigen receptor | UCL商务有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-113347994-B | Treatment and prevention of cancer using HER3 antigen binding molecules | 蜂鸟生物科技私人有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-115103685-A | Fusion proteins comprising programmed cell death ligand 1 protein and uses thereof | 格纳西尼有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-109234295-B | Method for synthesizing fatty alcohol acetate in microorganism body based on fatty acid | 赣南师范大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-115103709-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-115093479-A | CD20 binding molecules and uses thereof | IGM生物科学股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-113423826-B | Herbicide-resistant polypeptide, nucleic acid and application thereof | 山东舜丰生物科技有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-109071652-B | Antigen binding molecules comprising TNF family ligand trimers and tenascin binding modules | 豪夫迈·罗氏有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-108699153-B | Binding members of PD-L1 | 细胞医学瑞士公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-111909950-B | Gene for improving yield of spinosad in saccharosporium spinosum and application thereof | 中国科学院分子植物科学卓越创新中心 | 2022-09-23 | — | — | CN | disclosed |
| CN-115094036-A | Methods of treating cancer and infectious diseases using cell-based therapies | 爱默蕾大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-115103900-A | Yeast cells and methods for producing E8, E10-dodecadienyl coenzyme A, alexan and derivatives thereof | 费罗生物公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-115103857-A | Cell expressing immunoregulatory molecule and system expressing immunoregulatory molecule | 上海细胞治疗集团有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-109153703-B | Immunomodulator | 百时美施贵宝公司 | 2022-09-23 | — | — | CN | disclosed |
| WO-2022194042-A1 | PERIPHERAL BLOOD TCR MARKER FOR ACUTE MYELOID LEUKAEMIA, AND TEST KIT AND APPLICATION THEREOF | 成都益安博生物技术有限公司 | 2022-09-22 | — | — | WO | disclosed |
| WO-2022194039-A1 | PERIPHERAL BLOOD TCR MARKER FOR ACUTE B LYMPHOCYTIC LEUKEMIA, AND DETECTION KIT THEREOF AND USE THEREOF | 成都益安博生物技术有限公司 | 2022-09-22 | — | — | WO | disclosed |
| CN-114057840-B | Recombinant adeno-associated viral particles comprising variant AAV9 capsid proteins | 和元生物技术（上海）股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115087464-A | Novel interleukin-15 (IL-15) fusion proteins and uses thereof | 科优基因公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115074372-A | Recombinant African swine fever virus J18L subunit protein and preparation method and application thereof | 浙江海隆生物科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115074380-A | Heading stage regulation gene Ehd5 and application thereof | 中国科学院分子植物科学卓越创新中心 | 2022-09-20 | — | — | CN | disclosed |
| CN-115074331-A | Chimeric antigen receptor targeting PSCA | 希望之城公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-113024642-B | Protein based on mycoplasma pneumoniae and preparation method and application thereof | 珠海丽禾医疗诊断产品有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-113881650-B | Taq DNA polymerase mutant for probe method qPCR | 武汉爱博泰克生物科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068664-A | Bioadhesive compositions comprising mussel adhesive proteins and methods of making the same | 浦项工科大学校产学协力团 | 2022-09-20 | — | — | CN | disclosed |
| CN-109312401-B | Nanopore sequencing method for ligated nucleic acids | 牛津纳米孔科技公开有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-112321708-B | Peanut allergen Arah3 specific nano antibody and application thereof | 南开大学 | 2022-09-20 | — | — | CN | disclosed |
| US-11448657-B2 | Methods and kits for assessing Heparanase procoagulant activity, compositions comprising Heparanase, and methods for the treatment of coagulation-related disorders | RAMBAM MED-TECH (IL) | 2022-09-20 | — | — | US | disclosed |
| CN-115087749-A | Method and system for molecular disease assessment by analysis of circulating tumor DNA | 莱森特生物公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073609-A | Recombinant protein based on extracellular domain of African swine fever virus CD2v protein, and construction method and application thereof | 湖南派智生物科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073599-A | Antibodies that bind PD-L1 and uses thereof | 北京天广实生物技术股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115087740-A | Production of glycosylation products in host cells | 因比奥斯公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-112342224-B | Porphyra haitanensis glutamate dehydrogenase gene and application thereof | 中国科学院海洋研究所 | 2022-09-20 | — | — | CN | disclosed |
| CN-112390880-B | Lupin allergen Lupan1 specific nano antibody and application thereof | 南开大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-115074369-A | Adeno-associated virus vector for expressing full-length ABCA4 gene and application thereof | 成都金唯科生物科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073588-A | Method for improving safety of medicine containing immunoglobulin Fc fragment | 中山康方生物医药有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111154745-B | Chitin deacetylase, coding gene and application | 中国科学院大连化学物理研究所 | 2022-09-20 | — | — | CN | disclosed |
| CN-113512116-B | anti-IGF-1R antibody and application thereof | 苏州普乐康医药科技有限公司 | 2022-09-20 | — | — | CN | disclosed |
| US-11446365-B2 | Antimalarial enzyme conjugates, kits containing same, and methods of producing and using same | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-09-20 | — | — | US | disclosed |
| CN-115087461-A | Methods of treating cancer using combinations of PD-1 antagonists, ILT4 antagonists, and chemotherapeutic agents | 默沙东有限责任公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111433363-B | Plants having increased abiotic stress tolerance and polynucleotides and methods for increasing abiotic stress tolerance in plants | 未名生物农业集团有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-115066613-A | Diagnostic and therapeutic methods for treating hematologic cancers | 基因泰克公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-115066257-A | Treatment involving antigen vaccination and binding agents that bind to PD-L1 and CD137 | 生物技术公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-109608544-B | PD-L1 antibody, antigen binding fragment thereof and medical application thereof | 苏州盛迪亚生物医药有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-113661248-B | Inhibition of unintended mutations in gene editing | 上海科技大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-112409490-B | Taq enzyme 5 '-3' exonuclease activity blocking monoclonal antibody and application thereof | 翌圣生物科技(上海)股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-110945086-B | Coating for removing aldehydes and preparation method thereof | 陶氏环球技术有限责任公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-115058409-A | Mallotus japonicus pollen allergen triose phosphate isomerase and application thereof | 江苏省肿瘤医院 | 2022-09-16 | — | — | CN | disclosed |
| CN-115057931-A | Anti-human LAG-3 antibodies and uses thereof | 广州誉衡生物科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114767845-B | Recombinant influenza subunit vaccine | 天津中逸安健生物科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-115066235-A | Therapeutic combinations comprising ubiquitin-specific processing protease 1(USP1) inhibitors and poly (ADP-ribose) polymerase (PARP) inhibitors | KSQ治疗公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114807085-B | Taq enzyme mutant and application thereof | 翌圣生物科技(上海)股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| US-20220288204-A1 | DOSAGE AND ADMINISTRATION OF ANTI-ERBB3 (HER3) MONOCLONAL ANTIBODIES TO TREAT TUMORS ASSOCIATED WITH NEUREGULIN 1 (NRG1) GENE FUSIONS | ELEVATION ONCOLOGY, INC. | 2022-09-15 | — | — | US | disclosed |
| WO-2022191742-A1 | A METHOD FOR ASSESSMENT OF THE CELLULAR IMMUNE | DUKHOVLINOV ILYA VLADIMIROVICH (RU) | 2022-09-15 | — | — | WO | disclosed |
| US-20220291232-A1 | ASSAYS FOR DETERMINING PLASMA KALLIKREIN SYSTEM BIOMARKERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-09-15 | — | — | US | disclosed |
| CN-113444702-B | Enone reductase mutant and application thereof | 奥锐特药业股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052982-A | Squalene agamene cyclase (SHC) variants | 奇华顿股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-111748580-B | Method for detecting activity of immune checkpoint antibody | 百奥泰生物制药股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-110564771-B | Preparation method of cerebral calcification disease model | 中国科学院脑科学与智能技术卓越创新中心 | 2022-09-13 | — | — | CN | disclosed |
| CN-115043916-A | Methods and reagents for detecting antibodies against sesame nsLTP | 欧蒙医学实验诊断股份公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052662-A | Use of anti-TGF-beta antibodies and checkpoint inhibitors for treating proliferative diseases | 诺华股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115043943-A | Antagonistic anti-tumor necrosis factor receptor superfamily antibodies | 综合医院公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115043947-A | Krimeia-Congo hemorrhagic fever virus Zera-Gn protein nanoparticle, preparation method and application thereof | 宁夏大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-109880838-B | Recombinant virus for secretory expression of pig O-type foot-and-mouth disease virus multi-epitope gene and preparation method and application thereof | 华南农业大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-115044634-A | Application of Coprinus cinereus mannase | 南京师范大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-115040653-A | Compositions and methods for inhibiting MASP-1 and/or MASP-2 and/or MASP-3 | 奥默罗斯公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-108367004-B | CD3 binding polypeptides | 阿帕特夫研究和发展有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113508139-B | Antibodies that bind human LAG-3, methods of making, and uses thereof | 三生国健药业（上海）股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115043905-A | Peptide fragment composition for relatively quantitative analysis of porcine glycine amidine transferase GATM and application | 中国农业科学院北京畜牧兽医研究所 | 2022-09-13 | — | — | CN | disclosed |
| CN-112010975-B | LAG3 binding fragments and uses thereof | 山东博安生物技术股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-109929856-B | Application of rice fatty acid hydroxylase gene OsFAH2 | 华中农业大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-108473970-B | DNA polymerase variants | 国立大学法人九州大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052902-A | Lymphocyte-antigen presenting cell co-stimulating factor and application thereof | 上海优替济生生物医药有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115044627-A | Method for efficiently producing L-homophenylalanine and strain for producing L-homophenylalanine | 江南大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052884-A | Monospecific and multispecific antibodies | 北京烁星生物医药科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052604-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115044569-A | Taq DNA polymerase mutant and application thereof | 武汉爱博泰克生物科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052981-A | Mannanase variants and polynucleotides encoding same | 诺维信公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052887-A | LILRB 1-based chimeric antigen receptors | A2生物治疗公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115052862-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-106795484-B | Alpha (1,2) fucosyltransferase variants for use in the production of fucosylated oligosaccharides | 格里康辛有限责任公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115029377-A | Method for editing rice SSIIIa gene to cultivate high-resistance starch indica rice variety | 广东省农业科学院水稻研究所 | 2022-09-09 | — | — | CN | disclosed |
| CN-110577590-B | TCR capable of recognizing AFP antigen and encoding nucleic acid thereof | 香雪生命科学技术（广东）有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115038787-A | Novel branched-chain amino acid aminotransferase variants and leucine production methods using the same | CJ第一制糖株式会社 | 2022-09-09 | — | — | CN | disclosed |
| CN-113337536-B | Application of RS2Z32 gene as plant immune negative regulatory factor in improving crop resistance | 南京农业大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-115028727-A | MSLN-targeting trispecific proteins and methods of use | 哈普恩治疗公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115038786-A | Optimized tetrahydrocannabinolic acid (THCA) synthase polypeptides | 德美崔克斯公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115038789-A | Therapeutic editing | 塑造治疗公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-109562200-B | Spider silk coating of solid surfaces | 思百博技术股份公司 | 2022-09-09 | — | — | CN | disclosed |
| US-20220281932-A1 | METHODS AND COMPOSITIONS FOR REGENERATING TISSUES | NellOne Therapeutics, Inc. (US) | 2022-09-08 | — | — | US | disclosed |
| CN-115023437-A | Broadly neutralizing antibodies against HIV | 科隆大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-111303278-B | Human antibodies binding to RSV G protein | 扬森疫苗与预防公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-115011619-A | Application of cassava MeGLYI-13 gene and coding protein thereof in regulation and control of stress resistance of eukaryotes | 中国热带农业科学院热带生物技术研究所 | 2022-09-06 | — | — | CN | disclosed |
| CN-112028993-B | Nano antibody for resisting SARS-COV-2 virus N protein and its preparation method and use | 武汉华美生物工程有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114805580-B | Nano antibody targeting human LILRB2 and application thereof | 北京科诺信诚科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-112029001-B | Chimeric antigen receptors targeting NK activating receptors | 南京北恒生物科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-115010812-A | Multimer of African swine fever antigen-mediated cellular immunity and application | 河南省龙星生物科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-113501879-B | Bifunctional antibody for relieving immunosuppression in tumor immune microenvironment, and application and preparation method thereof | 拜盖特生物科技(上海)有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-115011616-A | Acetaldehyde dehydrogenase gene RKALDH and application thereof | 昆明理工大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-109825589-B | Application of LOC112268236 gene, nucleic acid composition for detecting methylation, kit and detection method thereof | 深圳市亚辉龙生物科技股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-115011569-A | Old yellow enzyme NemR-PS mutant and application thereof in preparation of (S) -citronellol | 浙江工业大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-115011572-A | Preparation method of variant tetraisopentenyl-beta-curcumene cyclase and ambroxol | 国立大学法人新潟大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-113151287-B | Pathogenic new gene of double kidney deficiency/double kidney dysplasia and application thereof | 中南大学湘雅医院 | 2022-09-06 | — | — | CN | disclosed |
| CN-112708649-B | Method for producing isomaltooligosaccharide by multi-enzyme coupling | 江南大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-115010810-A | anti-CTLA-4 antibodies and uses thereof | 南京圣和药业股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-115011579-A | Taq DNA polymerase mutant and preparation method and application thereof | 北京丹大生物技术有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-113201514-B | Polypeptides having aspartokinase activity and their use for producing amino acids | 中国科学院天津工业生物技术研究所 | 2022-09-06 | — | — | CN | disclosed |
| CN-115023443-A | anti-MDR 1 antibodies and uses thereof | 肯乔克蒂生物技术股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-108136025-B | A novel method of treating cancer using immunomodulation | 比奥克斯塞尔医疗股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-115011538-A | Escherichia coli for producing L-citrulline and construction method and application thereof | 江南大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-110072860-B | Compounds useful as immunomodulators | 百时美施贵宝公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-113234697-B | Glucose dehydrogenase variant and preparation method and application thereof | 遵义医科大学珠海校区 | 2022-09-02 | — | — | CN | disclosed |
| CN-115003790-A | Genetically modified bacteria with altered envelope integrity and uses thereof | 鲁汶大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-114606221-B | Immobilized enzyme, preparation method and application thereof | 凯莱英医药集团（天津）股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114984209-A | Combination therapy targeting PD-1, TIM-3 and LAG-3 | 西福根有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-115004030-A | Method | 牛津纳米孔科技公开有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-115003328-A | Recombinant neuraminidase and uses thereof | 西奈山伊坎医学院 | 2022-09-02 | — | — | CN | disclosed |
| CN-114990137-A | Arabidopsis thaliana calcium binding protein gene AtCAREF and application thereof | 鲁东大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-115003823-A | Biosynthetic platform for the production of cannabinoids and other prenylated compounds | 加利福尼亚大学董事会 | 2022-09-02 | — | — | CN | disclosed |
| CN-115003327-A | Methods of treating inflammatory or obstructive airway diseases using anti-TSLP antibodies | 诺华股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-115003699-A | Methods of use of anti-TREM 2 antibodies | 艾利妥 | 2022-09-02 | — | — | CN | disclosed |
| CN-114990132-A | Application of citrus CcLFY gene in regulation and control of shoot development | 华中农业大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-114990129-A | Preparation and application of mesenchymal stem cells expressing alpha PDL1 Fc fusion protein | 北京贝来生物科技有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-114350634-B | Glucoside glycosyl transferase for synthesizing epimedin and coding gene and application thereof | 湖北碳元本草生物科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114981448-A | Method for sequencing single cell proteins and nucleic acids | 宽腾矽公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-109897894-B | Pathogenic mutation of osteogenesis imperfecta disease and detection reagent thereof | 黄欢 | 2022-08-30 | — | — | CN | disclosed |
| CN-114958682-A | Application of Burkholderia renogel in preparation of products for inducing systemic resistance of plants or seeds thereof | 慕恩（广州）生物科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-109706171-B | Rice high photosynthetic efficiency gene HPE1 and application thereof | 中国农业科学院生物技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| CN-114957423-A | Application of ethylene-insensitive protein GmEIN3 in improving phosphorus absorption and utilization rate of plants and promoting root growth of plants | 河南农业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114958799-A | Taq DNA polymerase variant and application thereof in genome editing | 山东大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114981306-A | Multispecific antibodies | 努玛治疗有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114957490-A | PCV2-PCV3 fusion protein, and preparation method, gene, recombinant vector and application thereof | 龙湖现代免疫实验室 | 2022-08-30 | — | — | CN | disclosed |
| CN-114958797-A | Mutant DNA polymerase, coding gene, recombinant expression vector, recombinant bacterium and application thereof | 郑州思昆生物工程有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114958807-A | Alkali-resistant lipase mutant and application thereof | 山东隆科特酶制剂有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114949187-A | Methods of improving the benefit of a therapy or therapeutic agent | 汉莎生物制药股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-112898422-B | Tobacco ringspot virus monoclonal antibody and preparation method and application thereof | 中国计量大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114958800-A | Taq DNA polymerase mutant resistant to inhibition of blood or blood product and application thereof | 北京脉道生物药品制造有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114980871-A | Salmonella-based DNA vaccine in combination with antibiotics | 万科斯蒙股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-111548979-B | Recombinant escherichia coli for synthesizing lactoyl N-neotetraose and construction method and application thereof | 江南大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-111117987-B | High-specific-activity acidic mannase mutant | 青岛蔚蓝生物集团有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113088500-B | Glutamic dehydrogenase mutant, encoding gene and method for preparing L-glufosinate-ammonium | 浙江大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-109072216-B | Preparation method of mutant tetraisopentenyl-beta-curcumene cyclase and ambroxol | 国立大学法人新潟大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-112979819-B | Method for preparing kelp hydrolysate by using artificial enzyme | 山东宏业海洋科技股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-112760300-B | Aflatoxin degrading enzyme mutant and production strain thereof | 潍坊康地恩生物科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114958934-A | Method for preparing L-glufosinate-ammonium | 苏州百福安酶技术有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114591923-B | Cannabidiol synthetase mutant and construction method and application thereof | 森瑞斯生物科技(深圳)有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110511266-B | Small molecule polypeptide and application thereof | 南方医科大学南方医院 | 2022-08-30 | — | — | CN | disclosed |
| CN-114981443-A | Arenaviruses as vectors | 巴塞尔大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114981439-A | Non-viral transcriptional activation domains and methods and uses related thereto | 芬兰国家技术研究中心股份公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114945682-A | Biochemical reaction method and reagent containing inherent disorder region | 生物坩埚有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114945679-A | Method for double-strand sequencing | 牛津纳米孔科技公开有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114231605-B | Freeze-dried composition for nucleic acid amplification | 南京诺唯赞生物科技股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114940997-A | Application of GmBBE-like43 gene in regulation and control of plant adaptation to low phosphate and aluminum stress and growth promotion | 华南农业大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-114945571-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114945384-A | Highly sialylated multimeric binding molecules | IGM生物科学股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114945594-A | anti-LILRB 1 antibodies and uses thereof | 株式会社LG化学 | 2022-08-26 | — | — | CN | disclosed |
| CN-114945409-A | Methods of treating tumors with combinations of IL-7 proteins and bispecific antibodies | 新免疫技术有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114720645-B | Use of olfactory receptor for identifying 3-methylthiopropanal and method for detecting 3-methylthiopropanal | 汉王科技股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-108463103-B | Targeted mutagenesis of tobacco berberine bridge enzyme-like nucleic acids | 北卡罗来纳州立大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-112695024-B | Linoleic acid isomerase and application thereof in conjugated linoleic acid production | 江南大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-114933649-A | Anti-varicella-zoster virus antibody and application thereof | 北京智仁美博生物科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114716553-B | Nano antibody targeting human LILRB4 and application thereof | 北京科诺信诚科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-108368179-B | Methods of treating CEA positive cancers using PD-1 axis binding antagonists and anti-CEA/anti-CD 3 bispecific antibodies | 豪夫迈·罗氏有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114934033-A | Agarase mutant and coding gene and application thereof | 青岛海洋生物医药研究院股份有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-111411066-B | Double-way composite neuraminic acid-producing bacillus subtilis and construction method thereof | 江南大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-114934029-A | Taq DNA polymerase variant, obtaining method thereof and application thereof in genome editing | 山东大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-111094335-B | Broadly neutralizing anti-influenza monoclonal antibodies and uses thereof | 罗切斯特大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-112708570-B | Method for producing conjugated linoleic acid | 江南大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-114934030-A | High-specificity Taq DNA polymerase variant and application thereof in genome editing and/or gene mutation detection | 山东大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-114929888-A | Methods, kits and devices for preparing samples for multiplex polypeptide sequencing | 宽腾矽公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-111944023-B | Vaccine composition for resisting O-type foot-and-mouth disease and preparation method and application thereof | 普莱柯生物工程股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114921442-A | Enzyme variants and polynucleotides encoding same | 诺维信公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114924078-A | Detection method and application of cobratoxin and viperidae snake toxin | 上海赛伦生物技术股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114929734-A | Novel antigen binding molecules comprising 4-1BBL trimers | 豪夫迈·罗氏有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-112280723-B | Recombinant bacterium for co-production of 1, 3-propylene glycol and 1, 3-butanediol and application thereof | 清华大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114920840-A | Antibody molecules against PD-L1 and uses thereof | 诺华股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114917322-A | Immunopotentiator for micropterus salmoides | 湖州师范学院 | 2022-08-19 | — | — | CN | disclosed |
| CN-111925423-B | Vaccine composition for resisting O-type foot-and-mouth disease and preparation method and application thereof | 普莱柯生物工程股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114921443-A | Application of streptococcus pneumoniae endopeptidase O in preparation of antitumor drugs | 重庆医科大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-109790557-B | Controlling biofilm dispersion to produce amino acids or amino acid-derived products | 上海凯赛生物技术股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114929740-A | Insect prevention and control nano antibody and application thereof | IBI-AG创新生物杀虫剂有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114929887-A | Method for sequencing and reconstructing single polypeptide | 宽腾矽公司 | 2022-08-19 | — | — | CN | disclosed |
| US-20220257741-A1 | COMBINATION THERAPY FOR CANCER | IO BIOTECH APS (DK) | 2022-08-18 | — | — | US | disclosed |
| CN-114736891-B | Chitinase mutant ChiM-SS and application thereof | 深圳润康生态环境股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113166251-B | Anti-human TIM-3 monoclonal antibody and application thereof | 上海开拓者生物医药有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907271-A | Compositions of benzamide and active compound and methods of use thereof | 转化药物开发有限责任公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113493494-B | Epitope of EB virus BALF3 protein | 上海交通大学医学院附属瑞金医院 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907464-A | Peptides for promoting glucose transport | 努里塔斯有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907479-A | anti-CD 112R antibodies and uses thereof | 上海君实生物医药科技股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114908115-A | Application of chitosan binding domain amino acid sequence and saccharomyces cerevisiae spore immobilized enzyme method | 江南大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-112010973-B | Anti-4-1BB antibody, composition containing same and application thereof | 山东博安生物技术股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112646019-B | Mutant lysenin pore | 牛津纳米孔科技公开有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-110438212-B | Enzyme digestion PCR kit and method for enrichment detection of specific gene fragment | 黄种山 | 2022-08-16 | — | — | CN | disclosed |
| CN-114910653-A | Application of composition in preparation of kit for evaluating immunocompetence and related device | 珠海丽珠试剂股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114574589-B | Application of marker ZNF207 in preparation of lung adenocarcinoma diagnostic reagent and diagnostic kit | 深圳市第二人民医院(深圳市转化医学研究院) | 2022-08-16 | — | — | CN | disclosed |
| CN-114907458-A | Vip3A mutant protein with improved activity and application thereof | 山东大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907476-A | anti-TIGIT antibodies and uses thereof | 上海医药集团股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114910647-A | Application of filamin-A-IgG antibody in preparation of kit for detecting vascular endothelial injury | 浙江大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114908077-A | Phage lyase, chimeric substance and application thereof | 武汉乐斯吉生物科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-108884163-B | Neutralization of inhibitory pathways in lymphocytes | 依奈特制药公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114908068-A | Pear callose synthase PbrCalS5 and coding gene and application thereof | 南京农业大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114907478-A | LAG-3 binding antibodies and uses thereof | 迈威(上海)生物科技股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114901825-A | Production of sialylated oligosaccharides in host cells | 因比奥斯公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901826-A | Method for synthesizing coronatine II, method for synthesizing betaxanthin, beta-amyloid polymerization inhibitor or Alzheimer's disease therapeutic or preventive agent, amyloid peptide aggregation inhibitor, and HIV-1 protease activity inhibitor | 森正之 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901689-A | Treatment of cancer with ILT-2 inhibitors | 先天制药公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-110452894-B | High-temperature-resistant II-type restriction enzyme targeting AGCT (accelerated glycation-associated computed tomography) site and application thereof | 黄种山 | 2022-08-12 | — | — | CN | disclosed |
| CN-114895024-A | Kit for detecting anti-serine/arginine-rich splicing factor 9-IgG antibody | 浙江大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-110438103-B | Novel efficient normal-temperature II-type restriction endonuclease | 黄种山 | 2022-08-12 | — | — | CN | disclosed |
| CN-110387362-B | High-temperature-resistant restriction endonuclease capable of recognizing and cutting AGCT (accelerated glucose detection computed tomography) site | 黄种山 | 2022-08-12 | — | — | CN | disclosed |
| CN-110760532-B | Starch branching enzyme and gene thereof, engineering bacterium containing gene and application of engineering bacterium | 南京农业大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901816-A | Lipase-modified strains | 帝斯曼知识产权资产管理有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901691-A | ILT3 binding agents and methods of use thereof | 恩格姆生物制药公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901830-A | Method for producing plant growth promoter, and method for promoting plant growth | 松下知识产权经营株式会社 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901679-A | Brand-new masked cytokine and application thereof | 奥美药业有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114891761-A | Tth DNA polymerase mutant and application thereof | 上海威高医疗技术发展有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-113135995-B | anti-HER 3 monoclonal antibody and application thereof | 上海生物制品研究所有限责任公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-110923219-B | Mutants of cellobiohydrolases | 荣成市慧海创达生物科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901257-A | Protein 1(ARRDC1) constructs containing minimal arrestin domains | 哈佛大学的校长及成员们 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901814-A | Monomeric polypeptides having hydrogenase activity, in particular recombinant monomeric polypeptides having hydrogenase activity | H2WIN 股份公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901695-A | anti-GITR antibodies and uses thereof | 南京金斯瑞生物科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114901302-A | Compositions and methods for RNA-encoded DNA replacement alleles | 成对植物服务股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-112266420-B | Plant efficient cytosine single-base editor and construction and application thereof | 华南农业大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-111944024-B | Foot-and-mouth disease virus-like particle, preparation method, vaccine composition and application | 普莱柯生物工程股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111763261-B | Fusion protein and application thereof | 杭州尚健生物技术有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111394292-B | Multi-way composite neuraminic acid-producing bacillus subtilis and application thereof | 江南大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-113388040-B | African swine fever virus chimeric protein, vaccine composition, preparation method and application thereof | 普莱柯生物工程股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114875043-A | Betula platyphylla BpPIF4 gene participating in adventitious root development and application thereof | 东北林业大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-114874330-A | Neutralizing monoclonal antibodies targeting single chain antibodies | 南京驯鹿医疗技术有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111961655-B | Foot-and-mouth disease virus-like particle, preparation method, vaccine composition and application | 普莱柯生物工程股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-109718127-B | Nonionic bactericidal anti-inflammatory facial cleanser and preparation method thereof | 荣成市吉海生物科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110438100-B | Method for synthesizing glycerol glucoside through biocatalysis | 中国科学院天津工业生物技术研究所 | 2022-08-09 | — | — | CN | disclosed |
| CN-109219618-B | Monospecific and bispecific antibodies against epidermal growth factor receptor variants III and CD3 and uses thereof | 辉瑞大药厂 | 2022-08-09 | — | — | CN | disclosed |
| CN-112010974-B | Antibody specifically binding to human 4-1BB and application thereof | 山东博安生物技术股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114874990-A | Functional exosome and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2022-08-09 | — | — | CN | disclosed |
| CN-112921015-B | High-specificity Taq DNA polymerase variant and application thereof in genome editing and gene mutation detection | 山东大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-114874322-A | ILT7 binding molecules and methods of use thereof | 维埃拉生物股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114867751-A | 4-1BB and OX40 binding proteins and related compositions and methods, anti-4-1 BB antibodies, anti-OX 40 antibodies | 阿帕特夫研究和发展有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114853901-A | Construction and application of engineering bacteria for expressing antimicrobial peptide AFP1 fusion protein | 四川贝斯安贸易有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114853913-A | Fusion protein of plant antibacterial peptide AFP1 and bacillus secretory peptide SPamyQ and application | 五康生物科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114867852-A | V-type CRISPR-CAS base editor and method of use thereof | 成对植物服务股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114853868-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114867739-A | Fusion polypeptide comprising GDF15 and a polypeptide region capable of O-glycosylation | 株式会社LG化学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114854836-A | Method for monitoring marine environmental neurotoxic poison pollution | 浙江海洋大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114867738-A | Tumor targeting protein or fragment thereof, antibody binding thereto, and use thereof | 拜耳诺克斯有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114854722-A | Candida guilliermondii exo beta-1, 3-glucanase, mutant and application thereof | 成都普睿法药物研发有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111363775-B | Method for preparing L-glufosinate-ammonium by racemization removal with biological enzyme method, glufosinate-ammonium dehydrogenase mutant and application | 浙江工业大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114854708-A | Cordyceps militaris membrane protein beta-1, 3-glucan synthetase, and preparation method and application thereof | 江苏大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-110724677-B | Agarase and preparation method thereof | 中国海洋大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114867752-A | Degradation of surface proteins using bispecific binders | 加利福尼亚大学董事会 | 2022-08-05 | — | — | CN | disclosed |
| CN-114574465-B | Polymerase mutant and application thereof | 上海众启生物科技有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114854706-A | Alcohol dehydrogenase mutant and application thereof in production of beta-phenylethyl alcohol | 山东中酶生物科技有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114867347-A | Storage or transportation preparation of mesenchymal stem cells and preparation and use method thereof | 细胞研究私人有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114853862-A | Periplaneta americana GRP protein expression inhibitor and coding gene and application thereof | 岭南现代农业科学与技术广东省实验室 | 2022-08-05 | — | — | CN | disclosed |
| CN-114853900-A | Novel chimeric antigen receptor and use thereof | 南京北恒生物科技有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114853911-A | Trefoil factor 2/interferon alpha 2 fusion protein and application thereof in preventing and treating virus infectious diseases | 复旦大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114867744-A | Anti-yellow fever virus antibodies and methods of making and using same | 迈博洛克有限责任公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-110167967-B | Idiotypic antibodies directed against anti-PD-L1 antibodies and uses thereof | 豪夫迈·罗氏有限公司 | 2022-08-05 | — | — | CN | disclosed |
| WO-2022163852-A1 | COMPOSITION FOR INHIBITING EXPRESSION OF ANGIOTENSIN CONVERTING ENZYME 2 (ACE2) AND/OR TMPRSS2 | 株式会社 バイオミメティクスシンパシーズ | 2022-08-04 | — | — | WO | disclosed |
| US-20220244263-A1 | METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-04 | — | — | US | disclosed |
| CN-114846022-A | Enhancing disease resistance in crops by downregulation of repressor genes | 科沃施种子欧洲股份两合公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-111826366-B | Direct-amplification type hot-start DNA polymerase and preparation method and application thereof | 广州英赞生物科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114836404-A | Composite heat-resistant cellulase and preparation method and application thereof | 陕西理工大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-112175073-B | Neutralizing antibodies or antigen-binding fragments thereof to coronaviruses | 上海市公共卫生临床中心 | 2022-08-02 | — | — | CN | disclosed |
| CN-114846025-A | Ultra-long acting insulin-Fc fusion proteins and methods of use thereof | 阿卡斯通生物科学公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114846143-A | Expression of nitrogenase polypeptides in plant cells | 联邦科学技术研究组织 | 2022-08-02 | — | — | CN | disclosed |
| CN-113088529-B | Novel beta-glucan gene HG278 and application thereof | 温氏食品集团股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114846146-A | Engineered guide RNAs for increasing efficiency of CRISPR/Cas12f1 system and uses thereof | 基恩科雷有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114835784-A | Anti-inflammatory peptides and uses thereof | 努里塔斯有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114846136-A | Recombinant factor G derived from horseshoe crab and method for measuring beta-glucan using the same | 富士胶片株式会社 | 2022-08-02 | — | — | CN | disclosed |
| CN-114836427-A | Method for cultivating apoaequorin transgenic tomato and application thereof | 杭州师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114836457-A | Preparation and application of genetically engineered bacterium for producing chiral phenylglycine | 上海光玥生物科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-111378045-B | Bivalent and bispecific antibody, preparation method thereof, encoding gene, host cell and composition | 长春金赛药业有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-108368517-B | Methods and compositions for rapid plant transformation | 先锋国际良种公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114836451-A | Aryloxyphenoxy propionate herbicide hydrolysis esterase with chiral selectivity and application thereof | 淮北师范大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114829941-A | LAMA2, PLXDC2 and MLL4 as novel biomarkers for pre-diabetes and diabetes | 施明哲 | 2022-07-29 | — | — | CN | disclosed |
| CN-114828893-A | Engineered antibodies as molecular degradation agents through cellular receptors | 耶鲁大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114828888-A | Antibodies for binding plasminogen | 莫纳什大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805599-A | VLPs based on ADDomer chimeric swine O-type foot-and-mouth disease virus epitope and application thereof | 华南农业大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114828965-A | Antibodies that bind to HLA-A2/MAGE-A4 | 豪夫迈·罗氏有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829610-A | Method for improving photosynthetic organisms | 农牧研究公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805531-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805603-A | CTB/LTB polypeptide and VP8 fusion protein and rotavirus vaccine | 成都康华生物制品股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805607-A | EGFRvIII-PDL1-GMCSF tumor vaccine and preparation method and application thereof | 广州医科大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114806999-A | Genetically engineered bacterium and application thereof in preparing dihydrodaidzein | 华熙生物科技股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805580-A | Nano antibody targeting human LILRB2 and application thereof | 北京科诺信诚科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114807162-A | Method for improving photosynthetic efficiency and yield of rice | 武汉大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829400-A | anti-PD-L1 antibodies | 卡佩拉生物科学有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829942-A | Methods of assessing wound healing efficacy of a mesenchymal stem cell population and related methods of selecting mesenchymal stem cells and identifying tissues as starting materials for generating a mesenchymal stem cell population | 细胞研究私人有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114806984-A | Genetically engineered bacterium EC01S7 for co-production of 3-hydroxypropionic acid and 1, 3-propanediol, construction method and application | 江苏大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805583-A | Monoclonal antibody against HER2 | 根马布股份公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114807178-A | C-terminal multi-epitope recombinant antigen of African swine fever virus P72 protein and application thereof | 广东省农业科学院动物卫生研究所 | 2022-07-29 | — | — | CN | disclosed |
| CN-114807175-A | Monosaccharide transprotein gene OsSTP15, transporter thereof, application of transporter and amplification primer in increasing rice yield | 湖南农业大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805532-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114807074-A | Aflatoxin lyase, and coding gene, recombinant vector, recombinant bacterium and application thereof | 江西省科学院生物资源研究所 | 2022-07-29 | — | — | CN | disclosed |
| CN-114807085-A | Taq enzyme mutant and application thereof | 翌圣生物科技(上海)股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114807063-A | Aflatoxin lyase, and coding gene, recombinant vector, recombinant bacterium and application thereof | 江西省科学院生物资源研究所 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829618-A | Genetically engineered yeast cells and methods of use thereof | 伯克利发酵科学公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113462688-B | Blue light regulation promoter, fusion gene of blue light regulation promoter, blue light mediated regulation plasmid, construction method and application | 华中科技大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829592-A | Lactose-converting alpha-1, 2-fucosyltransferase | 因比奥斯公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114796452-A | Inflammatory skin disease biomarkers DDX5 and/or sIL-36R and uses thereof | 华东师范大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-107735098-B | Antimicrobial therapy | 加利福尼亚大学董事会 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805533-A | Modified FGF-21 polypeptides and uses thereof | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805519-A | Application of natural chia seed polypeptide in gonad function regulation | 广州金天芳颜化妆品有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114805496-A | Non-ribosomal polypeptide (NRPs) compounds, preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829595-A | Variants of CAS12A nuclease, methods of making and uses thereof | 成对植物服务股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113105554-B | Anti-tumor fusion protein and preparation method and application thereof | 广东泰禾医药科技有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-110511277-B | anti-HSP 90 monoclonal antibody and application thereof | 江苏莱森生物科技研究院有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114790248-A | MUC1-PDL1-IgG1Fc tumor vaccine as well as preparation method and application thereof | 广州医科大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-110835634-B | Novel base conversion editing system and application thereof | 华东师范大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-110982831-B | Application of gene AlgL23 with cold adaptability | 集美大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-111356702-B | anti-PD-L1 antibodies and antigen binding fragments thereof | 正大天晴药业集团南京顺欣制药有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-113842456-B | Anti-human 4-1BB monoclonal antibody preparation and application thereof | 上海齐鲁制药研究中心有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112251391-B | Construction method and application of lysine production strain | 中国科学院天津工业生物技术研究所 | 2022-07-26 | — | — | CN | disclosed |
| CN-112876570-B | African swine fever virus vaccine and preparation method thereof | 中国农业科学院生物技术研究所 | 2022-07-26 | — | — | CN | disclosed |
| CN-107106679-B | anti-TREM 2 antibodies and methods of use thereof | 艾利妥 | 2022-07-26 | — | — | CN | disclosed |
| CN-110835629-B | Construction method and application of novel base conversion editing system | 华东师范大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-107921111-B | Novel peptides, peptide compositions and scaffolds for immunotherapy of various cancers | 伊玛提克斯生物技术有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-111971062-B | Monoclonal antibody preparation against human PD-1, combined medicament and application thereof | 上海齐鲁制药研究中心有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114790242-A | Antibody capable of binding to human PD-L1 | 三生国健药业（上海）股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112979768-B | Antigen composition and kit for detecting mycoplasma synoviae antibody and application thereof | 山东绿都生物科技有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114786773-A | Benzothiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114773486-A | Immunomodulatory proteins with tunable affinity | 高山免疫科学股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114774394-A | Thermostable beta-galactosidase and application thereof in synthesizing glycerol galactoside | 南京工业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114787191-A | anti-PD-L1 antibody formulations | 基因泰克公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114774477-A | Method for producing ethanol using recombinant yeast | 丰田自动车株式会社 | 2022-07-22 | — | — | CN | disclosed |
| CN-113322195-B | Engineering bacterium for producing recombinant aspartic protease and application thereof | 江苏科技大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114786772-A | Benzothia (di) azepin compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114786722-A | Anti-chemokine receptor 1 humanized antibodies and therapeutic uses thereof | OSE免疫疗法公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114786709-A | IL-2 chimeric proteins for immunosuppression | 国家生物技术研究所公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114787347-A | Novel MAD nucleases | 因思科瑞普特公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114767846-A | Application of rotavirus NSP4 in improving immune function of recombinant rotavirus subunit vaccine | 中国医学科学院医学生物学研究所 | 2022-07-22 | — | — | CN | disclosed |
| CN-108431027-B | Charge-reversed N-terminal spider silk protein domains and uses thereof | 思百博技术股份公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114773475-A | PD-1 binding molecules and methods of use thereof | 宏观基因有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-113249397-B | Tabanus trehalase gene dsRNA and application thereof | 河北农业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114767833-A | Use of B7-H1 fusion polypeptide or polynucleotide for treating or preventing liver failure | 弗劳恩霍夫应用研究促进协会 | 2022-07-22 | — | — | CN | disclosed |
| CN-114767845-A | Recombinant influenza subunit vaccine | 天津中逸安健生物科技有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-111961656-B | Mutant of serine hydroxymethyl transferase and application thereof | 中国科学院上海高等研究院 | 2022-07-22 | — | — | CN | disclosed |
| CN-114774377-A | HPPD protein, gene, vector, cell, composition and application thereof, and method for improving herbicide resistance of crops | 华中师范大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-114774384-A | Taq DNA polymerase mutant and screening method thereof | 浙江大学杭州国际科创中心 | 2022-07-22 | — | — | CN | disclosed |
| CN-114787928-A | Methods and systems for identifying, classifying and/or ordering genetic sequences | 雷杰纳荣制药公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114099660-B | Trivalent gene engineering subunit vaccine composition for preventing duck infectious serositis and preparation method thereof | 扬州优邦生物药品有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-112996817-B | Homodimer type bispecific antibody and preparation method and application thereof | 安源医药科技（上海）有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-109943547-B | Tea tree sucrose synthase CsSUS587, preparation method and application | 安徽农业大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-113930405-B | Novel thermostable phosphorylation and adenylylation one-step catalytic enzyme, and preparation method and application thereof | 温州医科大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-107404924-B | Oxidized dextran | 营养与生物科学美国4公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-112010956-B | Wheat booting stage root depth related gene TaVSR1-B and encoding protein and application thereof | 中国农业科学院作物科学研究所 | 2022-07-19 | — | — | CN | disclosed |
| CN-114761803-A | Methods of diagnosing cancer using anti-BAG 2 antibodies | 株式会社麦迪帕克特 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761559-A | Method for capturing candidate substance capable of binding to complex of MR1 protein and β 2 microglobulin, method for producing candidate substance capable of binding to complex of MR1 protein and β 2 microglobulin, and method for producing ligand candidate substance for MAIT cell | 国立大学法人大阪大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-108700574-B | Antigens of soybean allergy | 朋友股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-112687352-B | Polypeptide vaccine combination aiming at targeted drug ibrutinib and design method thereof | 杭州纽安津生物科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-112063626-B | Corn gene ZmRAVL1 and functional site and application thereof | 中国农业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114748618-A | Pharmaceutical formulation comprising bispecific antibody against rabies virus G protein and method for the preparation thereof | 重庆智翔金泰生物制药股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114751989-A | Antigen binding molecules comprising trimeric TNF family ligands | 豪夫迈·罗氏有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761079-A | Benzothia (di) azepin compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761802-A | Method for identifying T cell receptor | 大学健康网络 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761080-A | Benzothia (di) azepin compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761033-A | Medicament for radical therapy of refractory hereditary nephrotic Alport syndrome | 国立大学法人熊本大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761430-A | Chimeric protein targeting PD-L1 and application thereof | 奥里尼斯生物科学股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114752581-A | Alpha-galactosidase mutant and application thereof | 南京工业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761018-A | Benzothiadiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-111378044-B | Antibody fusion protein, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-108778312-B | Methods of treating cancer and infectious diseases using cell-based therapies | 爱默蕾大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-113388595-B | High-efficiency terminal A-added mutant Taq DNA polymerase and encoding DNA thereof | 武汉翌圣生物科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761438-A | Recombinant polypeptides for programming extracellular vesicles | 麦克马斯特大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114761087-A | Hybrid antibodies | 艾普西洛根有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114751983-A | HER3 antigen binding molecules | 蜂鸟生物科技私人有限公司 | 2022-07-15 | — | — | CN | disclosed |
| US-20220220213-A1 | Compositions and Methods for Enhancing Body Weight and Lean Muscle Mass Using Antagonists Against Leptin Receptor, GDF8 and Activin A | REGENERON PHARMA (US) | 2022-07-14 | — | — | US | disclosed |
| CN-112852859-B | Method for improving synthesis capacity of filamentous fungi organic acid | 中国科学院天津工业生物技术研究所 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736275-A | Insecticidal polypeptides having an improved activity profile and uses thereof | 先锋国际良种公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736890-A | Application of rice chitinase and coding gene thereof in enhancing abiotic stress resistance of plants | 中国农业科学院作物科学研究所 | 2022-07-12 | — | — | CN | disclosed |
| CN-114732052-A | Methods and compositions for affecting flavor and odor characteristics of consumer products | 非凡食品有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114746450-A | Compositions and methods for neurological diseases | 科达生物治疗医药有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-108220246-B | Compounds for improving viral transduction | 蓝鸟生物公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112687354-B | Polypeptide vaccine composition of kinase inhibitor aiming at targeted drugs PI3K, AKT and mTOR pathways and design method thereof | 杭州纽安津生物科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-107614014-B | Affinity ligands and methods relating thereto | 生物辐射实验室股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114746110-A | Vaccine and immunoglobulin targeting African swine fever virus, and methods of making and using the same | IGY免疫技术和生命科学公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736891-A | Chitinase mutant ChiM-SS and application thereof | 深圳润康生态环境股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-111363028-B | Recombinant human type I collagen, expression strain and construction method thereof | 江苏江山聚源生物技术有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110204614-B | Anti-human LAG-3 monoclonal antibody and preparation method and application thereof | 广州誉衡生物科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736277-A | Forward regulation factor for regulating salt tolerance of corn, InDel molecular marker and application thereof | 河南农业大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-114746448-A | Bispecific fusion proteins for tumor therapy | 江苏康宁杰瑞生物制药有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736303-A | Bifunctional antibody for resisting PD-L1 and 4-1BB and medical application thereof | 英诺湖医药(杭州)有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114732017-A | Agrochemical composition comprising an antibody that binds to a sphingolipid | 阿格罗塞文公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112899257-B | Thermophilic chitinase Chi304 mutant and application thereof in degradation of chitin | 中国农业科学院生物技术研究所 | 2022-07-12 | — | — | CN | disclosed |
| CN-111926018-B | Application of substance for reducing USP1 expression in preparation of medicine for treating children T-line acute lymphoblastic leukemia | 首都医科大学附属北京儿童医院 | 2022-07-12 | — | — | CN | disclosed |
| CN-114746445-A | Methods of inhibiting or activating γ δ T cells | 墨尔本大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-114717213-A | N-terminal truncated mutant enzyme of dextran sucrase and preparation method thereof | 广西科学院 | 2022-07-08 | — | — | CN | disclosed |
| CN-110579608-B | Method for screening non-integrated attenuated Listeria strain with high-expression foreign protein | 苏州若泰医药科技有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716544-A | Complement component C5 antibody | 阿勒根公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729338-A | Mutant dihydrodipicolinate reductase polypeptide and method for producing L-threonine using the same | CJ第一制糖株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716563-A | Fusion protein and preparation and application thereof | 中国科学院沈阳应用生态研究所 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729030-A | Virus-like particle vaccine | 沃达瑞公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728072-A | TGF-beta polypeptides | 库尔生物制药有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729041-A | High affinity nanobodies targeting B7H3(CD276) for the treatment of various solid tumors | 美国政府(由卫生和人类服务部的部长所代表) | 2022-07-08 | — | — | CN | disclosed |
| CN-114716552-A | Humanized, mouse or chimeric anti-CD47 monoclonal antibodies | 四十七公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716567-A | Preparation method and application of chimeric antigen and anti-bungarus fasciatus snake venom preparation | 上海赛伦生物技术股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114720645-A | Use of olfactory receptor for recognizing 3-methylthiopropanal and method for detecting 3-methylthiopropanal | 汉王科技股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716541-A | Anti-coronavirus fully human broad-spectrum neutralizing antibody 76E1 and application thereof | 中国科学院分子细胞科学卓越创新中心 | 2022-07-08 | — | — | CN | disclosed |
| CN-114727583-A | Modified exopolysaccharide receptors for identifying and structuring microbial populations | 奥尔胡斯大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728066-A | Compositions and methods relating to human neutralizing antibodies to hepatitis b | 洛克菲勒大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728171-A | anti-TIGIT antibody and application thereof | 默克专利有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729024-A | Peptide antigens and uses thereof | 博爱米拉索勒股份公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113512541-B | Novel phosphorylated adenylyl acylase and preparation method and application thereof | 温州医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729285-A | Use of deoxyribonuclease in detergent compositions | 诺维信公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114712487-A | Use of disordered protein sequences for combating biological contamination | 清华大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729303-A | Electron mediator, method for producing electron mediator, and method for transferring electrons | 松下知识产权经营株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729049-A | Antigen binding proteins | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716514-A | Composition for colon cleansing and treatment of gastrointestinal disorders | 硬木药品公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729031-A | Anti-oncolytic antigen antibodies and methods of use thereof | 艾德梅尔治疗协会 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729016-A | Enzyme mutant for producing 3-aminoisobutyric acid | 南京纽邦生物科技有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114716553-A | Nano antibody targeting human LILRB4 and application thereof | 北京科诺信诚科技有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729343-A | Novel class 2 type II and type V CRISPR-CAS RNA-guided endonucleases | 科学方案有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729366-A | Extracellular vesicle-ASO constructs targeting CEBP/beta | 科迪亚克生物科学公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729327-A | Extracellular vesicles with STAT3 antisense oligonucleotides | 科迪亚克生物科学公司 | 2022-07-08 | — | — | CN | disclosed |
| US-20220211037-A1 | BIOSENSORS FOR DROUGHT STRESS IN PLANTS | UNIV CALIFORNIA (US) | 2022-07-07 | — | — | US | disclosed |
| CN-114699518-A | Foot and mouth disease vaccine | 硕腾服务有限责任公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-110483631-B | Apolygus intermedius reproduction related protein PG, coding gene thereof, dsRNA interference sequence and application | 华中农业大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112029671-B | Recombinant aspergillus terreus strain for producing trans-aconitic acid and preparation method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-114507658-B | Enzyme coexpression system and application thereof in synthesizing sialic acid | 深圳瑞德林生物技术有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114181310-B | anti-TIGIT antibody, and pharmaceutical composition and use thereof | 中山康方生物医药有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114702597-A | Construction and application of engineering bacteria for expressing plant antibacterial peptide Ct-AMP1 | 四川宜美康科技有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-108026504-B | Microorganisms with increased lipid production | 合成基因组股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-109735477-B | Preparation and application of three-gene deletion attenuated mutant strain of Listeria monocytogenes | 扬州大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-112011468-B | Recombinant aspergillus terreus for producing trans-aconitic acid and preparation method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-114703167-A | Improved blood clotting compositions | Q-塞拉有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-111411065-B | Recombinant bacterium for producing N-acetylneuraminic acid based on artificial double carbon sources | 江南大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-114703200-A | Apple drought-tolerant negative regulatory gene MdbHLH108 and application thereof | 河南农业大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-111875699-B | Method for improving bacillus subtilis ovalbumin expression level | 江南大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-114703144-A | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114560937-B | anti-FGL 1 antibody and application thereof | 山东博安生物技术股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-112011469-B | Recombinant aspergillus terreus strain for producing trans-aconitic acid and construction method and application thereof | 中国科学院青岛生物能源与过程研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-108350450-B | Agent for separating human serum-derived IgG polyclonal antibody, and method for separating human serum-derived IgG polyclonal antibody using same | 国立大学法人京都工艺纤维大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-114702578-A | Novel coronavirus Omicron mutant strain specific antibody and application thereof | 百斯医学诊断科技(北京)有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114702569-A | PD-L1 related vaccine and application thereof | 深圳吉诺因生物科技有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114686519-A | Method for preparing serine protease | 佛山汉腾生物科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-111139255-B | Propanil amidase gene pamD and coding protein and application thereof | 南京农业大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685663-A | Anti-cholesterol-dependent cytolysin antibody and application thereof | 西南大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685633-A | Method for cultivating drought-resistance-changed plant, ZmMADS27 protein and coding gene thereof | 中国农业大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114686497-A | Gene MnGutB1 for improving mulberry DNJ biosynthesis and application thereof | 西南大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685623-A | Virus-like particles of GII 2 type norovirus and use thereof | 远大赛威信生命科学(南京)有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685622-A | Norovirus virus-like particles and uses thereof | 远大赛威信生命科学(南京)有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685624-A | Virus-like particles of GII 17 type norovirus and uses thereof | 远大赛威信生命科学(南京)有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685685-A | RNA editing fusion protein and application thereof | 上海科技大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685625-A | Virus-like particles of GI 1 type norovirus and use thereof | 远大赛威信生命科学(南京)有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110327459-B | Fusion vaccine targeting immune checkpoint PD-L1 for combating pathogen infection | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 2022-07-01 | — | — | CN | disclosed |
| CN-114686500-A | 1, 4-alpha-glucan branching enzyme, coding gene, engineering strain and application | 华东师范大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685620-A | Norovirus virus-like particles and uses thereof | 远大赛威信生命科学(南京)有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-111560389-B | Tobacco mitogen-activated protein kinase gene NtMAPK8 and application thereof | 云南中烟工业有限责任公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114680126-A | Control of noctuid, snout moth's larva and snout moth's larva harmful organism | 先正达生物科技（中国）有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-111733140-B | Hybridoma cell strain resisting canine matrix metalloproteinase, preparation method thereof, monoclonal antibody and application thereof | 华中农业大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-109734806-B | Fully human anti-huTIGIT monoclonal antibody and application thereof | 安徽安科生物工程（集团）股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-112010976-B | anti-LAG3 antibodies and uses thereof | 山东博安生物技术股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685621-A | Norovirus immune composition or kit | 远大赛威信生命科学(南京)有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-20220204600-A1 | THERAPEUTIC PROTEIN FORMULATIONS COMPRISING ANTI-DNABII ANTIBODIES AND USES THEREOF | TRELLIS BIOSCIENCE, INC. (US) | 2022-06-30 | — | — | US | disclosed |
| CN-114679909-A | MAdCAM-targeted immune tolerance | 潘迪恩运营公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-108350443-B | Polypeptides having xanthan degrading activity and polynucleotides encoding same | 诺维信公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-107428804-B | Immunomodulator | 百时美施贵宝公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-112639086-B | Herbicide-resistant gene, polypeptide and application thereof in plant breeding | 山东舜丰生物科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-114671947-A | High-affinity nano antibody for different subtype surface S proteins of hepatitis B virus and application thereof | 中国科学院生物物理研究所 | 2022-06-28 | — | — | CN | disclosed |
| CN-114679910-A | Polypeptides for the treatment of pathological thrombosis | 免疫功坊股份有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-113249346-B | Herbicide-resistant polypeptide, nucleic acid and application thereof | 山东舜丰生物科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| US-11369624-B2 | Salts of prodrugs of piperazine and substituted piperidine antiviral agents | VIIV HEALTHCARE UK (NO. 4) LIMITED | 2022-06-28 | — | — | US | disclosed |
| US-11372002-B2 | Assays for determining plasma kallikrein system biomarkers | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-06-28 | — | — | US | disclosed |
| CN-114672553-A | Application of KRT15 in auxiliary diagnosis and targeted therapy of esophageal cancer | 中国医学科学院肿瘤医院 | 2022-06-28 | — | — | CN | disclosed |
| CN-111718911-B | FAD-dependent oxidase Ma-2 in Diels-Alder adduct anabolic pathway and application | 中国中医科学院中药研究所 | 2022-06-28 | — | — | CN | disclosed |
| CN-114657192-A | EBNA1 truncated mRNA related vaccine and preparation method and application thereof | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2022-06-24 | — | — | CN | disclosed |
| CN-114656565-A | anti-PD-L1 antibody and application thereof | 广东菲鹏制药股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114657166-A | Additional endoglucanase variants and methods | 福尼亚生物处理股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114652853-A | anti-IL-4R antibody-drug conjugate and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114657198-A | Recombinant engineering bacterium and application thereof in preparing pan-compound | 安徽华恒生物科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114652813-A | Macrocyclic peptides as immunomodulators | 百时美施贵宝公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114667343-A | Escherichia coli composition and method thereof | 辉瑞大药厂 | 2022-06-24 | — | — | CN | disclosed |
| CN-112521500-B | Affinity maturation binding proteins that bind to CXCR4 and uses thereof | 暨南大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114667336-A | Use of cellulase for improving detergent sustainability | 诺维信公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-111909279-B | Staphylococcus aureus and streptococcus agalactiae immunogen fusion expression and application thereof | 石河子大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114657173-A | Modular polypeptide libraries and methods of making and using the same | 加利福尼亚大学董事会 | 2022-06-24 | — | — | CN | disclosed |
| CN-114657075-A | Aspergillus niger strain for producing itaconic acid, method and application | 天津科技大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114657199-A | Recombinant engineering bacterium and application thereof in preparation of D-pantothenic acid | 安徽华恒生物科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114652816-A | Compositions containing HC-HA/PTX3 complexes and methods of use thereof | 组织技术公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-112675297-B | Polypeptide vaccine composition for targeted drugs abiraterone, enzalutamide, flutamide and ketoconazole and design method thereof | 杭州纽安津生物科技有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114657186-A | Phyllostachys pubescens leaf shape regulating gene PheLBD29 and application thereof | 安徽农业大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114657200-A | Recombinant engineering bacterium and method for preparing D-pantoic acid by using same | 安徽华恒生物科技股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| WO-2022132059-A1 | ANTIMICROBIAL PROTEIN, ANTIMICROBIAL RECOMBINANT PROTEIN WITH LYTIC PROPERTIES, EXPRESSION VECTOR, METHOD OF THEIR PREPARATION AND USE | USTAV MOLEKULARNEJ BIOLOGIE SAV (SK) | 2022-06-23 | — | — | WO | disclosed |
| CN-108431217-B | Method for producing lipase | 诺维信公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-112661845-B | Affinity maturation binding protein bound with CXCR4 and application thereof | 暨南大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-113736800-B | Pigeon-derived Newcastle disease virus recombinant vaccine strain and construction method and application thereof | 中国动物卫生与流行病学中心 | 2022-06-21 | — | — | CN | disclosed |
| CN-109180815-B | anti-CEACAM 5 antibodies and uses thereof | 赛诺菲 | 2022-06-21 | — | — | CN | disclosed |
| CN-112209357-B | Metal cobalt phosphate and preparation method and application thereof | 江苏大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-113924316-B | anti-CD 25 antibodies and uses thereof | 山东博安生物技术股份有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114645057-A | Caragana korshinskii drought-tolerant gene Chr8.229 and application thereof in preparation of drought-tolerant transgenic plants | 兰州大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-114380913-B | Fully human anti-PD-L1 antibody and application thereof | 上海济煜医药科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114651004-A | Novel interleukin-2 variants for cancer treatment | 科优基因公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-111454341-B | Gene for promoting plant floral organ enlargement and application thereof | 北京林业大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-109692130-B | Mask liquid containing defensins and preparation method thereof | 威海同丰海洋生物科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114645058-A | Caragana korshinskii drought-tolerant gene Chr8.231 and application thereof in preparation of drought-tolerant transgenic plants | 兰州大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-108602887-B | Bispecific antibodies specific for co-stimulatory TNF receptors | 豪夫迈·罗氏有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114651060-A | Modified cyanobacterium, method for producing modified cyanobacterium, and method for producing protein | 松下知识产权经营株式会社 | 2022-06-21 | — | — | CN | disclosed |
| CN-112608383-B | Single-chain antibody for resisting paralichthys rhabdovirus | 青岛农业大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-114645059-A | Caragana korshinskii drought-tolerant gene Chr8.226 and application thereof in preparation of drought-tolerant transgenic plants | 内蒙古农业大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-109692129-B | Shaving cream containing defensins and preparation method thereof | 威海同丰海洋生物科技有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114072422-B | Neutralizing antibody of SARS-CoV-2 virus and its application | 山东博安生物技术股份有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114645065-A | Novel photo-chemical small molecule double-induction gene expression system | 华东理工大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-114650844-A | anti-CD 47 antibodies, activatable anti-CD 47 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114642726-A | Stable anti-PD-1/PD-L1 bispecific antibody liquid preparation | 三生国健药业（上海）股份有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114650842-A | anti-TIM-3 antibodies | 单细胞技术股份有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-109182370-B | Plant polygene expression vector, transformant and application thereof | 浙江大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634923-A | Adenosine deaminase, base editor fusion protein, base editor system and use | 尧唐(上海)生物科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-109312375-B | Preparation method of hesperetin, preparation method of hesperetin intermediate and biological enzyme for preparing hesperetin | 邦泰生物工程(深圳)有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634575-A | Development and application of complement inhibitor | 康诺亚生物医药科技（成都）有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114641496-A | Multispecific binding proteins for cancer therapy | 勃林格殷格翰国际有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-112921013-B | Soybean cyst nematode chitin synthetase gene and application thereof | 中国农业科学院植物保护研究所 | 2022-06-17 | — | — | CN | disclosed |
| CN-109867723-B | Anti-human IL6 monoclonal antibody and preparation method and application thereof | 南京金斯瑞生物科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634557-A | Modified Factor H Binding Proteins (FHBP) and methods of use thereof | 奥克兰儿童医院及研究中心 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634572-A | Meditope and meditope binding antibodies and uses thereof | 希望之城公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634573-A | Antibodies against lymphocyte activation gene 3(LAG-3) | 安奈普泰斯生物有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114641307-A | anti-CD 19 antibodies and uses thereof | 艾佩斯瑞生物制药公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634965-A | High-throughput screening method of malonate transporter mutant library, mutant and application of mutant in synthesis of 3-hydroxypropionic acid | 青岛农业大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-110404066-B | Monoclonal antibody preparation for resisting human PD-1, combined medicament and application thereof | 齐鲁制药有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114641311-A | anti-TNFR 2 antibodies and methods of use thereof | 埃派斯进有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634561-A | Tumor specific polypeptide, T cell receptor for recognizing tumor specific polypeptide and application of tumor specific polypeptide and T cell receptor | 深圳华大生命科学研究院 | 2022-06-17 | — | — | CN | disclosed |
| CN-114641571-A | Treatment and prevention of WWP2 mediated diseases | 新加坡国立大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-111004791-B | Beta-agarase and application thereof in agar quantitative detection | 中国海洋大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113912709-B | Novel coronavirus monoclonal antibody and application thereof | 深圳国家感染性疾病临床医学研究中心 | 2022-06-17 | — | — | CN | disclosed |
| EP-4011914-A1 | ANTIBODIES DIRECTED AGAINST LYMPHOCYTE ACTIVATION GENE 3 (LAG-3) | AnaptysBio, Inc. (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-111235081-B | Microorganism for biosynthesis of Corcarpine and method thereof | 赣南师范大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621350-A | Chimeric immunoglobulins | 东莞市朋志生物科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-108431036-B | Antibodies neutralizing human respiratory syncytial virus | 默沙东公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621222-A | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114630676-A | Human anti-PD-L1 peptide vaccines and methods of use thereof | 俄亥俄州创新基金会 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621940-A | Protein with DNA polymerase activity and application thereof | 厦门大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114630903-A | Modified polypeptide of meso-diaminopimelate dehydrogenase and method for producing L-threonine using same | CJ第一制糖株式会社 | 2022-06-14 | — | — | CN | disclosed |
| US-11359020-B2 | Agents that modulate immune cell activation and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| CN-107475216-B | Recombinant heat-resistant DNA polymerase and application thereof | 北京擎科生物科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114624445-A | Method and reagent for diagnosing membranous nephropathy | 欧蒙医学实验诊断股份公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-108289494-B | Polypeptides capable of producing glucans with alpha-1, 2 branching and uses thereof | 营养与生物科学美国4公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621349-A | Targeting PD-L1/HSA/CCL5 trispecific nanobody, and derivative and application thereof | 青岛大学附属医院 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621347-A | Antibodies that bind AXL | 根马布股份公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114630842-A | Pharmaceutical formulations and dosage regimens of multispecific binding proteins that bind HER2, NKG2D and CD16 for cancer therapy | 蜻蜓疗法股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114630905-A | Biocatalytic process for controlled degradation of terpene compounds | 弗门尼舍有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621937-A | Mutant of serine hydroxymethyl transferase and application thereof | 武汉远大弘元股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621982-A | Biosynthesis method of geranyl diphosphate and application of geranyl diphosphate in preparation of cannabis compounds | 嘉兴欣贝莱生物科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114601933-A | Antibody drug conjugate, intermediate thereof, preparation method and application | 上海复旦张江生物医药股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-113527497-B | anti-Trop 2 nano antibody and application thereof | 上海洛启生物医药技术有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114616326-A | Biosynthesis of cannabinoids from cannabigerolic acid using novel cannabinoid synthase | 新加坡国立大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114605509-A | YH 66-01475 protein and application of encoding gene thereof in regulation and control of bacterial arginine yield | 宁夏伊品生物科技股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114606227-A | High-precision adenine base editor and application thereof | 复旦大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-114616031-A | Multimeric antibodies with enhanced selectivity for cells with high target density | IGM生物科学股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114606221-A | Immobilized enzyme, preparation method and application thereof | 凯莱英医药集团（天津）股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114605536-A | Affinity purification method for reducing host cell protein content in production of anti-human thymic stromal lymphopoietin monoclonal antibody | 江苏荃信生物医药股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114616318-A | Cell culture piece reaches large capacity cell culture case including it | 阿莫生命科学有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-108650889-B | Immunoassay for diagnosing viral infections | 欧蒙医学实验诊断股份公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114605547-A | Affinity entities with TCR-like antibody binding domains and uses thereof | 阿迪塞特生物公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114605507-A | Mutant CSGG pore | 弗拉芒区生物技术研究所 | 2022-06-10 | — | — | CN | disclosed |
| CN-114606215-A | Argonaute protein derived from eukaryote and application thereof | 湖北大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-108546302-B | Composite multi-epitope expression cassette, recombinant virus composed of same and application thereof | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 2022-06-10 | — | — | CN | disclosed |
| CN-114616333-A | Abiotic stress tolerant plants and methods | 未名生物农业集团有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-111138533-B | Single domain antibody against hepatitis A virus and derived protein thereof | 南京融捷康生物科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| WO-2022119481-A1 | VACCINE FOR PREVENTING AND TREATING A CORONAVIRUS INFECTION | ОРЛОВ, Антон Иосифович | 2022-06-09 | — | — | WO | disclosed |
| CN-114591923-A | Cannabidiol synthetase mutant and construction method and application thereof | 森瑞斯生物科技(深圳)有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108431220-B | Polypeptides having beta-glucanase activity, polynucleotides encoding same and use thereof in cleaning and detergent compositions | 诺维信公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591405-A | Feline calicivirus vaccine | 英特维特国际股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-110903371-B | Tobacco cellobiose-related protein NtCRP1 and application thereof | 中国烟草总公司郑州烟草研究院 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599787-A | Sustainable production of cannabinoids from simple precursor materials using Saccharomyces Cerevisiae | 新加坡国立大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-112011497-B | Recombinant lactococcus lactis for secretory expression of swine-derived enterotoxigenic escherichia coli K88 pilus single-chain antibody and preparation method thereof | 上海交通大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113444155-B | MERS-CoV membrane protein receptor binding domain dimer, and coding gene and application thereof | 清华大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-108848669-B | ROR1 antibody compositions and related methods | 斯克利普斯研究所 | 2022-06-07 | — | — | CN | disclosed |
| CN-114316062-B | Multispecific antibody targeting HIV gp120 protein and human CD3 molecule and application thereof | 珠海臻谱基因科技有限公司北京分公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591400-A | FoxM1-DBD targeting polypeptide and application thereof | 西南交通大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-108271357-B | Molecular constructs for treatment of transplant rejection | 免疫功坊股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599373-A | DDX17 and NLRC4 targeting inflammatory diseases | 弗吉尼亚大学专利基金会 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599786-A | Immobilized enzyme composition for producing hexose | 博努莫斯股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599674-A | T cell modulating chimeric molecules and methods of use thereof | 库尔生物制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599779-A | Strains and methods for single cell protein or biomass production | 太阳食物有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599394-A | Compositions and methods for minimizing protein loss at low protein concentrations | 安进公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599392-A | anti-CD 47 and anti-CD 20 based treatment of leukemia | 四十七公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591931-A | Acetylxylan esterase cloning expression and application thereof in papermaking stickies control | 江南大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591953-A | Construction method of CD163 gene swine mouse model | 江苏集萃药康生物科技股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114369586-B | Taq DNA polymerase mutant and application thereof, product, gene, plasmid and genetic engineering bacteria | 南京巨匠生物科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114599665-A | Compositions, formulations and interleukin production and purification | 应用分子转运公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591425-A | Specific antibody of new coronavirus S protein RBD region and preparation method and application thereof | 生物岛实验室 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591978-A | Application of OsFLR14 gene in improving resistance of rice to weeds | 湖南大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-108779169-B | Antibodies to immune complexes comprising cyanobacterial cyclopeptide hepatotoxin | 图尔库大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591988-A | Preparation method of genetically modified stem cells for activating tumor immunity | 北京贝来生物科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-107531806-B | Fusion proteins | 伊莱利利公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591939-A | High-heat-resistance D-psicose-3-epimerase mutant and application thereof | 天津科技大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-114588256-A | Development and application of porcine infectious pleuropneumonia subunit vaccine | 牧原食品股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114574459-A | Glycogen branching enzyme mutant with improved catalytic activity and application thereof | 中国科学院天津工业生物技术研究所 | 2022-06-03 | — | — | CN | disclosed |
| CN-114573714-A | Conjugate for target molecule modification and preparation method thereof | 北京大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585645-A | Cell surface receptors responsive to loss of heterozygosity | A2生物治疗公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114574465-A | Polymerase mutant and application thereof | 上海众启生物科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585637-A | MASP inhibiting compounds and uses thereof | 拜耳公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113416232-B | Polypeptide compounds with PD-1 receptor as target spot, preparation method and application thereof | 南通大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-111763683-B | Cryptomeria fortunei CfICE1 gene and application thereof | 南京林业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-114574513-A | Polysorium CcTLS2 protein, coding gene and application thereof | 中国农业科学院蔬菜花卉研究所 | 2022-06-03 | — | — | CN | disclosed |
| CN-114574589-A | Application of marker ZNF207 in preparation of lung adenocarcinoma diagnostic reagent and diagnostic kit | 深圳市第二人民医院(深圳市转化医学研究院) | 2022-06-03 | — | — | CN | disclosed |
| CN-114585726-A | Trichoderma fungal strains modified for production of complex enzymes | 能源与材料国家研究中心 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585258-A | Bacterial compositions for controlling fungal spoilage and uses thereof | 科·汉森有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113425852-B | Conjugate capable of penetrating blood labyrinth barrier and preparation method thereof | 北京大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113265401-B | Method for improving resistance of rice to HPPD inhibitor herbicide through gene editing and special sgRNA thereof | 江苏里下河地区农业科学研究所 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585390-A | Aminobenzazepine compounds, immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114573704-A | PD-1/CTLA-4 binding protein and medical application thereof | 北京拓界生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114574500-A | Clone and application of rice sword-leaf sheath and panicle whitening trait gene OsWSSP | 中国农业科学院深圳农业基因组研究所 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585730-A | Engineering regulatory T cells | 伦敦国王学院 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585731-A | Mutant hydroxyphenylpyruvate dioxygenase polypeptide, coding gene and application thereof | 北京大北农生物技术有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-108929886-B | Method for producing target substance | 味之素株式会社 | 2022-06-03 | — | — | CN | disclosed |
| US-20220170936-A1 | EVALUATION AND TREATMENT OF BRADYKININ-MEDIATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-06-02 | — | — | US | disclosed |
| WO-2022112430-A1 | REDUCTION OF VIRAL INFECTIONS | PHOXBIO LIMITED (IE) | 2022-06-02 | — | — | WO | disclosed |
| EP-4005600-A1 | CYTOTOXIC-DRUG DELIVERING MOLECULES TARGETING HIV (CDM-HS), CYTOTOXIC ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF USE | Yale University (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-108368177-B | Antigen binding proteins that activate leptin receptor | 瑞泽恩制药公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-112661829-B | Bioactive peptide GGYGSGGGSGGYGSRRF, and preparation method and application thereof | 浙江辉肽生命健康科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114560937-A | anti-FGL 1 antibody and application thereof | 山东博安生物技术股份有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113082221-B | Preparation method of Tyr/Ang dual-modified artesunate nano-targeting preparation and application of preparation in craniocerebral tumor treatment | 中国人民解放军陆军特色医学中心 | 2022-05-31 | — | — | CN | disclosed |
| US-11344610-B2 | Prevention and reduction of blood loss | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-05-31 | — | — | US | disclosed |
| CN-112724237-B | Bioactive peptide GGSDGYGSGRGF, and preparation method and application thereof | 浙江辉肽生命健康科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114560911-A | Antifungal peptide and preparation method thereof | 中国农业大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-114557450-A | Use of early harvested rice fruits for preparing weight-reducing and probiotic-promoting composition | 大江生医股份有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-108290953-B | anti-PD-1 antibodies and compositions | 西福根有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-112439056-B | Self-assembly ferritin-based nano antigen particle, O-type foot-and-mouth disease vaccine prepared from same and application | 中国农业科学院生物技术研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-113045676-B | Antibody for resisting CD19 protein molecule and application thereof | 北京荣瑷医学生物科技有限责任公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-109734786-B | Plant pollen fertility restorer related protein TaDMT25, and coding gene and application thereof | 北京市农林科学院 | 2022-05-31 | — | — | CN | disclosed |
| CN-108948195-B | anti-EGFR/PD-L1 double-targeting antibody, preparation method and application thereof | 胡毅 | 2022-05-31 | — | — | CN | disclosed |
| CN-110106181-B | Migratory locust low density lipoprotein receptor related gene 2LmLRP2And application of dsRNA thereof in locusta migratoria control | 山西大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113774040-B | B-family fumonisin degrading enzyme, construction method and application thereof | 中国科学院上海营养与健康研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-111214667-B | Electric response micelle magnetic resonance probe with core-shell structure and preparation method and application thereof | 复旦大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-114561406-A | Gene participating in synthesis of cationic peptide compound and application thereof | 北京工商大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-111321173-B | Application of mannase in alcohol fermentation | 南京百斯杰生物工程有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-112195188-B | Application of rice gene OsDES1 | 中国水稻研究所 | 2022-05-31 | — | — | CN | disclosed |
| CN-109735547-B | Promoter for improving pichia pastoris exogenous protein expression quantity and application thereof | 青岛蔚蓝生物集团有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-109071630-B | Endo-S2 mutant as glycoside synthase, method for production and use for glycoengineering of glycoproteins | 马里兰大学帕克分校 | 2022-05-31 | — | — | CN | disclosed |
| CN-107847596-B | anti-ROR 1 antibodies | 优瑞科生物技术公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114555780-A | Production of a biological product in a host cell | 因比奥斯公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555779-A | Recombinant microorganism and process for producing diamine compound | 旭化成株式会社 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540324-A | DNA polymerase, aptamer, hot start DNA polymerase, and method and application | 中山大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555792-A | Recombinant engineered, lipase/esterase deficient mammalian cell lines | 伊莱利利公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555817-A | Rhamnose polysaccharide | 敦提大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-108456697-B | Application of lentiviral vector EF1 alpha promoter to optimized expression of ABCD1 gene for treating adrenoleukodystrophy | 成都优娃生物科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555797-A | Biosynthesis of cannabinoid precursors using novel aromatic prenyltransferases | 新加坡国立大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539374-A | GmZTL3 protein, application of coding gene thereof and method for cultivating soybean | 东北农业大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-107454906-B | Combination therapy using coagulation factors and multispecific antibodies | 豪夫迈·罗氏有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540399-A | Method for preparing L-valine and gene mutant and biological material used by same | 宁夏伊品生物科技股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114556100-A | Therapy guidance and/or therapy monitoring for treatment of shock | 4TEEN4制药有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540385-A | Method for producing lysostaphin by using escherichia coli | 齐鲁工业大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-110438055-B | Whole-cell catalyst containing phenylpyruvate decarboxylase mutant and application of whole-cell catalyst in production of phenethyl alcohol | 湖北大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540329-A | Lactase mutant | 潍坊康地恩生物科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539403-A | Rabbit recombinant monoclonal antibody of targeted human BCMA protein and application | 缔码生物科技(武汉)有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539418-A | Bispecific antibodies and uses thereof | 上海华奥泰生物药业股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-113234160-B | anti-PD-1 antibody and application thereof | 广州爱思迈生物医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-110913908-B | MSLN-targeting trispecific proteins and methods of use | 哈普恩治疗公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540316-A | Oncolytic virus and uses thereof | 上海荣瑞医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112877345-B | Gene of cysteine desulfurization enzyme TP0614, recombinant protein thereof and application | 中南大学湘雅三医院 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555637-A | Antibodies to ILT2 and uses thereof | 比昂生物制剂公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555816-A | Improved process for the production, recovery and secretion of hydrophobic compounds in fermentation | 佰欧菲洛公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540304-A | Cell-based methods for determining botulinum toxin activity | 秀杰股份公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540323-A | GtfB enzyme with 4, 3/6-alpha-glucosyltransferase activity | 江南大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555820-A | Kinase activity signatures for predicting non-small cell lung cancer patient response to PD-1 or PD-L1 immune checkpoint inhibitors | 帕姆基因有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555113-A | Method for preventing dengue fever and hepatitis A | 武田疫苗股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555116-A | Administration for anti-TIGIT and anti-PD-L1 antagonist antibody therapy | 豪夫迈·罗氏有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555796-A | Compositions and methods for modifying plant characteristics without modifying the genome of a plant | 由农业部部长代表的美利坚合众国 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555119-A | Prophylactic and/or therapeutic agent for inflammatory lung disease | 国立大学法人冈山大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-111278861-B | PD-L1 antibody, antigen binding fragment thereof and medical application | 江苏恒瑞医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555812-A | Materials and methods for protein production | 非凡食品有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540325-A | Method for targeted DNA demethylation, fusion protein and application thereof | 广州医科大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114540319-A | Alkene reductase mutant, engineering bacteria and application of alkene reductase mutant in preparation of (2R,5R) -dihydrocarvone | 浙江工业大学 | 2022-05-27 | — | — | CN | disclosed |
| US-11340237-B2 | Metabolite biomarkers for diseases associated with the contact activation system | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-05-24 | — | — | US | disclosed |
| CN-114531878-A | Novel ICOS antibodies and tumor-targeted antigen-binding molecules comprising same | 豪夫迈·罗氏有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-114028562-B | Liquid formulation comprising anti-human Thymic Stromal Lymphopoietin (TSLP) monoclonal antibody | 江苏荃信生物医药股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-109734790-B | Human Agrin antigen, human Agrin antibody detection kit, preparation method and application thereof | 武汉明德生物科技股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-107074917-B | Insecticidal polypeptides having an improved activity profile and uses thereof | 先锋国际良种公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-111893122-B | Gene related to rice leaf color variation, premature senility and stress tolerance, protein coded by gene and application of protein | 中国水稻研究所 | 2022-05-24 | — | — | CN | disclosed |
| CN-114524866-A | Plant endogenous gene influencing feeding of lepidoptera insects and protein thereof | 沧州市农林科学院 | 2022-05-24 | — | — | CN | disclosed |
| CN-111676182-B | Method for producing refined ketone mixture by utilizing recombinant corynebacterium crenatum through fermentation | 江南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-111454918-B | Enol reductase mutant and application thereof in preparation of (R) -citronellal | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-111909907-B | Aspartate oxidase mutant, engineering bacteria and application of aspartate oxidase mutant in preparation of refined glufosinate-ammonium through oxidation-reduction coupling | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114525259-A | Chimeric antigen receptor targeting CD7 and uses thereof | 南京北恒生物科技有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110256583-B | Fusion protein of IL-2 mutant and antibody and application thereof | 中国科学院生物物理研究所 | 2022-05-20 | — | — | CN | disclosed |
| CN-109867725-B | PD-1-Fc fusion protein and preparation method and application thereof | 香雪生命科学技术（广东）有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-112239505-B | Method for capturing recombinant anti-CD 171 octavalent antibody and nerve-derived exosome | 上海良润生物医药科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111303286-B | anti-CD19 fully human antibody or antibody fragment, chimeric antigen receptor thereof and application thereof | 常州费洛斯药业科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516921-A | Fusion protein based on single-chain antibody fragment, nano assembly, preparation method and application thereof | 华南理工大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-114028561-B | Preparation method of anti-human Thymic Stromal Lymphopoietin (TSLP) monoclonal antibody concentrated solution | 江苏荃信生物医药股份有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516922-A | Chimeric antigen receptor containing third signal receptor and application thereof | 上海隆耀生物科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111041009-B | Short-chain dehydrogenase, mutant thereof, preparation and application of gene | 沈阳药科大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-111138532-B | Use of single domain antibodies against hepatitis a virus | 南京融捷康生物科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-113897376-B | HN protein mutated gene VII type Newcastle disease virus recombinant vaccine strain | 中国动物卫生与流行病学中心 | 2022-05-20 | — | — | CN | disclosed |
| CN-114507282-A | Human monoclonal anti-PD-L1 antibodies and methods of use | 达纳－法伯癌症研究所公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-111575260-B | Application of SAM dependent methyltransferase DmtMT2-1 | 中国海洋大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-114514317-A | Production of lactase using a strain with altered regulation | 科·汉森有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114507658-A | Enzyme coexpression system and application thereof in sialic acid synthesis | 深圳瑞德林生物技术有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114504651-A | Antibodies, uses and methods | 科马布有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114504652-A | Antibodies, uses and methods | 科马布有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-111349645-B | Method for improving safety of non-integrated attenuated listeria vaccine | 上海若泰医药科技有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-110846294-B | Recombinant pectinase, gene thereof, recombinant vector, preparation method and application | 怀化学院 | 2022-05-17 | — | — | CN | disclosed |
| CN-111971303-B | anti-CD 27 antibodies and uses thereof | 苏州丁孚靶点生物技术有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114507284-A | anti-TIGIT antibody, preparation method and application thereof | 华博生物医药技术（上海）有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114507275-A | Application of OsOSM1 protein and coding gene thereof in regulation and control of low-temperature tolerance of plants | 中国科学院植物研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-114507608-A | Recombinant filamentous fungus for producing ethanol in mitochondria and construction and application thereof | 中国科学院天津工业生物技术研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-114507647-A | Spartina alterniflora salt-tolerant protein P5CS2 and coding gene and application thereof | 自然资源部第一海洋研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-114106182-B | Antibodies against TIGIT and uses thereof | 中山康方生物医药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-110592189-B | Multi-site genotyping method for Listeria monocytogenes | 北京市食品安全监控和风险评估中心（北京市食品检验所） | 2022-05-17 | — | — | CN | disclosed |
| CN-114507285-A | VISTA antigen binding molecules | 蜂鸟生物科技私人有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-112094837-B | Recombinant arginine deiminase mutant, preparation method and application thereof | 浙江大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-108138167-B | Method for preparing linalool | 味之素株式会社 | 2022-05-17 | — | — | CN | disclosed |
| CN-110846332-B | Pectinase artificial sequence, and expression method and application thereof | 怀化学院 | 2022-05-17 | — | — | CN | disclosed |
| CN-109475617-B | anti-LAG-3 antibodies and uses thereof | 天境生物科技(杭州)有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-112266887-B | Bacillus thuringiensis | 中国农业科学院植物保护研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-110747212-B | Gene of novel pectinase, protein expression, vector and application thereof | 怀化学院 | 2022-05-17 | — | — | CN | disclosed |
| CN-108603185-B | Enzyme variants and polynucleotides encoding same | 诺维信公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-112011545-B | Gene for regulating flowering time and biomass of plant and use thereof | 中国科学院分子植物科学卓越创新中心 | 2022-05-17 | — | — | CN | disclosed |
| CN-114478803-A | Construction and application of novel bispecific chimeric antigen receptor | 北京大学深圳研究生院 | 2022-05-13 | — | — | CN | disclosed |
| CN-114502588-A | anti-PD-L1 single-domain antibody and derivative and application thereof | 普米斯生物技术(珠海)有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114502200-A | Antibody drug conjugates | 深圳康源久远生物技术有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-113683694-B | Anti-human TSLP monoclonal antibody and application thereof | 江苏荃信生物医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114480322-A | Oat glycosyltransferase AsUGT73E5 and application thereof in synthesis of steroid saponin | 东北林业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478769-A | anti-TIGIT antibody, and pharmaceutical composition and use thereof | 中山康方生物医药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478779-A | Humanized phosphatidylinositolglycan 3 monoclonal antibody and application thereof | 华中农业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478780-A | Antibody for recognizing multiple different epitopes of glypican 3 and application thereof | 华中农业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114502720-A | Bacteria comprising a myo-inositol to propanoic acid pathway | 瓦格宁根大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-111893098-B | Phenylalanine dehydrogenase and preparation method and application thereof | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478751-A | Application of diaphorina citri insulin receptor gene DcIR in preventing and treating diaphorina citri | 华南农业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478720-A | Non-catalytic protein gene for promoting enzymolysis of lignocellulose and non-catalytic protein and application thereof | 淮阴工学院 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478791-A | Constructs targeting AFP peptide/MHC complexes and uses thereof | 优瑞科生物技术公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114480328-A | Taq DNA polymerase mutant | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114470193-A | Antibody agents specific for human CD19 and uses thereof | 优瑞科生物技术公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114502733-A | Flowering phase genes and methods of use thereof | 未名生物农业集团有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-107602696-B | Humanized universal light chain mice | 瑞泽恩制药公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114502191-A | Method of eliciting an immune response by administering a population of polymersomes with associated antigens and a population of polymersomes with associated adjuvants and composition comprising both populations of polymersomes | ACM生物实验室私人有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114480327-A | TaqDNA polymerase mutant | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114480323-A | Oat glycosyltransferase AsUGT73E1 and application thereof in synthesis of steroid saponin | 东北林业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478790-A | Antibodies that specifically bind to PD-1 and TIM-3 and uses thereof | 詹森生物科技公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114480465-A | Bacillus subtilis for producing 2' -fucosyllactose and application thereof | 江南大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-111848798-B | Nanometer antibody capable of combining BCMA and application thereof | 源道隆（苏州）医学科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114470192-A | Antibody agents specific for human CD19 and uses thereof | 优瑞科生物技术公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478795-A | Fusion protein for improving oral administration stability of polypeptide medicine and application thereof | 安徽新熙盟生物科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114457117-A | Dendritic cell tumor vaccine and uses thereof | 深圳市珈钰生物科技有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456272-A | Constructs targeting AFP peptide/MHC complexes and uses thereof | 优瑞科生物技术公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456994-A | Recombinant staphylococcus aureus for preparing bacterial membrane vesicle multi-vaccine and preparation method and application thereof | 中国人民解放军陆军军医大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-112322602-B | Method for promoting extracellular expression of protein in bacillus subtilis by coexpression phospholipase | 江南大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-114466930-A | Method for transactivating a gene homologous to a target gene and in vitro method for diagnosing a disease | 维格内罗有限责任公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114466934-A | Production of fucosyllactose in host cells | 因比奥斯公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-112280757-B | Application of anthrax fatty acid hydroxylase CsSCS7 | 海南大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-110951754-B | Tamarix hispida COL transcription factor coding gene and application thereof | 东北林业大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-111808897-B | Method for biologically preparing mannan oligosaccharide | 中国科学院天津工业生物技术研究所 | 2022-05-10 | — | — | CN | disclosed |
| CN-114457091-A | Gene TaXip influencing wheat grain quality and application thereof | 山东农业大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-114438147-A | Enzyme and use thereof | 奇华顿股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-112300291-B | High-specific-activity fusion xylanase mutant and application thereof | 南京工业大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-114450392-A | Advanced microbiome therapy engineered to produce serotonin in vivo | 丹麦技术大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437227-A | Bispecific antibodies and uses thereof | 百奥泰生物制药股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437217-A | Affinity entities with TCR-like antibody binding domains and uses thereof | 阿迪塞特生物公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114450307-A | Genetically engineered cells and uses thereof | 苏州克睿基因生物科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114450023-A | Vaccine composition against severe fever with thrombocytopenia syndrome virus | 首尔大学校产业协力团 | 2022-05-06 | — | — | CN | disclosed |
| CN-113980971-B | Mutant Marfan syndrome pathogenic gene FBN1 and application thereof | 百世诺（北京）医疗科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114438053-A | DNA polymerase mutant and application thereof | 厦门大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437232-A | Cell surface macromolecule quantitative display system and preparation method and application thereof | 中国科学院分子细胞科学卓越创新中心 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437228-A | Bifunctional fusion protein formed by IL-2 and antibody subunit | 中国科学院生物物理研究所 | 2022-05-06 | — | — | CN | disclosed |
| CN-114450303-A | MHC class II molecules and methods of use thereof | 大学健康网络 | 2022-05-06 | — | — | CN | disclosed |
| CN-114450305-A | anti-CD 137L antibodies and methods of use thereof | 天演药业公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-108495863-B | Humanized, mouse or chimeric anti-CD 47 monoclonal antibodies | 四十七公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-112029751-B | Production method and application of thermophilic fungus mannase | 中国农业大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-111172173-B | Method for reducing plant height of corn or delaying flowering | 未米生物科技(江苏)有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-108753798-B | Preparation method and application of candidate outer membrane protein of aeromonas hydrophila vaccine | 福建农林大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-111057151-B | Monovalent blood brain barrier shuttle modules | 豪夫迈·罗氏有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-109415747-B | Preparation method of enzyme modified stevioside, enzyme for preparation and application | 邦泰生物工程(深圳)有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-114426962-A | t-PA purification process | 佛山汉腾生物科技有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-107548418-B | Method for separating and purifying ambrox | 奇华顿股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-113186190-B | Blue light mediated regulation plasmid and construction method and application thereof | 华中科技大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-108367067-B | Fusion protein of FMDV and E2 and application thereof | 勃林格殷格翰动物保健美国公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-111621482-B | Glufosinate-ammonium dehydrogenase mutant, gene engineering bacteria and one-pot multi-enzyme synchronous directed evolution method | 浙江工业大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-108026172-B | Monoclonal anti-IL-1 RACP antibodies | 赛诺菲生物技术公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114409769-A | Rift valley fever virus humanized monoclonal antibody and application thereof | 中国科学院微生物研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-114409773-A | Nanobodies against novel coronaviruses and uses thereof | 上海洛启生物医药技术有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410606-A | Neurodegenerative disorders | 神经生物有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114423862-A | Production of oligosaccharides | 银杏生物制品公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410605-A | Method for promoting recombinant protein extracellular expression by using cutinase mutant | 江南大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-112300987-B | Screening method of single plasma cell and application of screening method in preparation of small molecule monoclonal antibody | 中国农业大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-114423783-A | anti-VEGF protein composition and preparation method thereof | 瑞泽恩制药公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-112143746-B | Gene GmAP5 for improving disease resistance of plants and application thereof | 南京农业大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-107108698-B | Macrocyclic peptides as immunomodulators | 百时美施贵宝公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410650-A | Rice salt sensitive mutant gene SS2, mutant SS2 and application | 广东省农业科学院农业质量标准与监测技术研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410677-A | Method for creating low-nicotine tobacco mutant by using CRISPR/Cas9 to knock out NtBBBLs and application | 云南中烟工业有限责任公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114423871-A | Template-free enzymatic synthesis of polynucleotides using poly (A) and poly (U) polymerases | DNA斯克瑞普特公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114423779-A | Foot and mouth disease virus vaccine composition | 株式会社准绳生命科学 | 2022-04-29 | — | — | CN | disclosed |
| CN-114409770-A | Rift valley fever virus humanized monoclonal antibody and application thereof | 中国科学院微生物研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410625-A | RNA-guided DNA cleavage by Cas9-crRNA complex | 维尔纽斯大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-114423497-A | Modified cytotoxic T cells and methods of use thereof | 库尔生物制药有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-109554433-B | Rapid drug screening method based on CD47/SIRP alpha blocking function and biological effect thereof | 杭州科兴生物科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114409783-A | Anti-human transferrin receptor antibodies across the blood brain barrier | JCR制药股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114423861-A | Expression of modified proteins in peroxisomes | 起源生物有限责任公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410640-A | Aptamer for detecting measles virus, kit and application | 世通兰达(深圳)生物科技发展有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114410610-A | Cyclomaltodextrinase and preparation method and application thereof | 自然资源部第三海洋研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-114423283-A | Animal model for neurodegenerative disorders | 神经生物有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114392345-A | Application and method of E199L protein in promoting apoptosis | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 2022-04-26 | — | — | CN | disclosed |
| CN-111732658-B | GITR monoclonal antibodies and medical application thereof | 英诺湖医药(杭州)有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-108025045-B | Affinity entities for TCR-like antibody binding domains with high affinity and excellent specificity and uses thereof | 阿迪塞特生物公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114402105-A | Enzymatic treatment of pulp | 诺维信公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114395624-A | Methods for treatment and diagnosis of cancer | 基因泰克公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-108285483-B | Human antibodies and specific binding sequences thereof for use in stroke and ischemic or ischemic conditions | 梅奥医学教育和研究基金会 | 2022-04-26 | — | — | CN | disclosed |
| CN-114401994-A | anti-VEGF protein composition and preparation method thereof | 瑞泽恩制药公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-107849142-B | Antagonistic anti-tumor necrosis factor receptor superfamily antibodies | 综合医院公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114402070-A | Novel L-threonine dehydratase variants and methods of producing L-isoleucine using same | CJ第一制糖株式会社 | 2022-04-26 | — | — | CN | disclosed |
| CN-114401992-A | Antibodies to IGSF11(VSIG3) that bind IGC2 and uses thereof | 艾欧麦克斯治疗股份公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114395500-A | Oleic acid production in yeast | 银杏生物制品公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-114395049-A | Modified peptide material of targeting SARS-CoV-2S protein RBD, preparation method and application thereof | 清华大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-114395573-A | Method for improving yield of itaconic acid produced by whole cell catalysis by using aconitate decarboxylase | 南京工业大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-114395547-A | Mutant of beta-galactosidase and application of mutant in milk | 江南大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-110225770-B | Fibronectin type III domain binding to CD8A | 杨森生物科技公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-111748531-B | Application of USP33 as medication target in preparation of medicines | 中国科学院北京基因组研究所(国家生物信息中心) | 2022-04-26 | — | — | CN | disclosed |
| CN-114381468-A | Methionine lyase and coding gene and application thereof | 湖北工业大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-114380913-A | Fully human anti-PD-L1 antibody and application thereof | 上海济煜医药科技有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114380922-A | Fusion protein for generating point mutation in cell, preparation and application thereof | 中国科学院上海营养与健康研究所 | 2022-04-22 | — | — | CN | disclosed |
| CN-112375754-B | Severe acute respiratory syndrome coronavirus 2 affinity polypeptide based on human angiotensin converting enzyme 2 | 清华大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-114390937-A | Methods and compositions for treating smith-magenis syndrome | 加利福尼亚大学董事会 | 2022-04-22 | — | — | CN | disclosed |
| CN-114381446-A | Heat-resistant and acid-resistant arabinosidase gene and expression protein, recombinant vector, recombinant bacterium and application thereof | 淮阴工学院 | 2022-04-22 | — | — | CN | disclosed |
| CN-114380909-A | Antibodies specific for glycosylated PD-L1 and methods of use thereof | 斯特库比股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114365792-A | Methods and compositions for generating ovalbumin | 克莱拉食品公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114375304-A | Protein composition and food thereof | 克莱拉食品公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-111424006-B | Recombinant cell and application thereof in synthesizing alpha, beta-unsaturated aldehyde | 浙江工业大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-114369586-A | Taq DNA polymerase mutant and application thereof, product, gene, plasmid and genetic engineering bacteria | 南京巨匠生物科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-113490517-B | Chimeric peptide modified SIS membrane, preparation method and application thereof | 北京博辉瑞进生物科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-112239756-B | Group of cytosine deaminases from plants and their use in base editing systems | 科稷达隆(北京)生物技术有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114369166-A | Bifunctional fusion protein formed by anti-PD-L1 antibody and IL-2 | 苏州泽璟生物制药股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114375342-A | Improved virus detection method | 东洋纺株式会社 | 2022-04-19 | — | — | CN | disclosed |
| CN-114375199-A | African swine fever vaccine | 皮尔布莱特研究所 | 2022-04-19 | — | — | CN | disclosed |
| CN-112143764-B | Method for preparing intermediate compound of brivaracetam by using biological enzyme catalysis | 奥锐特药业股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114369167-A | Bifunctional fusion protein composed of anti-PD-L1 antibody and IL-7 | 苏州泽璟生物制药股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-113447648-B | Kit for detecting anti-serine/arginine-rich splicing factor 9-IgG antibody | 浙江大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-107075523-B | Cannabichromenic acid synthase from cannabis | 加拿大国家研究委员会 | 2022-04-19 | — | — | CN | disclosed |
| CN-114369169-A | Compositions for preventing or treating viral and other microbial infections | 优瑞科生物技术公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114369583-A | Immobilized enzyme and application thereof in continuous production | 凯莱英生命科学技术(天津)有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114369588-A | Neutral cellulase mutant and application thereof | 潍坊康地恩生物科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114375335-A | Optimized protein linkers and methods of use | 成对植物服务股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114375310-A | Several heterodimers and several methods of use thereof | 卡尔医学有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-108138121-B | High-level production of long-chain dicarboxylic acids by microorganisms | 纳幕尔杜邦公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-107073095-B | Acinetobacter baumannii vaccine based on lipopolysaccharide-deleted cell components | 瓦克斯丁公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114364695-A | Antibody specifically recognizing C5A and application thereof | 舒泰神（北京）生物制药股份有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114364984-A | A method of diagnosing or monitoring renal function or diagnosing renal dysfunction in a pediatric patient | 思芬构技术有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114350631-A | Glufosinate-ammonium dehydrogenase mutant, engineering bacteria, immobilized cell and application | 浙江工业大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349866-A | PD-1/TGF-beta tetravalent bispecific antibody, preparation method and application thereof | 丹生医药技术(上海)有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-112625994-B | Recombinant vibrio natriegens and application thereof | 清华大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-112410315-B | Method for producing long-chain glycosylated sophoricoside | 江南大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-113402596-B | RR-2 family epidermal protein of scarab beetle, coding nucleotide sequence and application thereof | 中国农业科学院农业基因组研究所 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349868-A | Novel coronavirus S protein receptor binding domain fusion protein containing oligomerization structural domain and application thereof | 中国医学科学院基础医学研究所 | 2022-04-15 | — | — | CN | disclosed |
| CN-109234307-B | Use of insecticidal proteins | 北京大北农生物技术有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114364703-A | Anti-merk antibodies and methods of use thereof | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349832-A | Application of calmodulin binding protein COLD13 in regulating and controlling COLD tolerance of plants | 中国科学院植物研究所 | 2022-04-15 | — | — | CN | disclosed |
| CN-114350634-A | Glucoside glycosyl transferase for synthesizing epimedin and coding gene and application thereof | 湖北碳元本草生物科技有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-112940095-B | Bombyx mori BmSPI51 mutant protein BmSPI51M and preparation method and application thereof | 西南大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-114349865-A | PD-1/LAG-3 tetravalent bispecific antibody, preparation method and application thereof | 丹生医药技术(上海)有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-111303257-B | Positive regulation gene AtMIF1 for oil content of plant seeds and application thereof | 武汉大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-112391365-B | Starch branching enzyme mutant with improved catalytic activity and application thereof | 江南大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-114350583-A | Method for producing 1, 2-butanediol through fermentation, recombinant microorganism and application of recombinant microorganism | 清华大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-114364793-A | HPPD mutant protein with herbicide resistance and application thereof | 江苏省农业科学院 | 2022-04-15 | — | — | CN | disclosed |
| CN-114364700-A | Antibodies that bind NKG2D | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-109385447-B | Use of insecticidal proteins | 北京大北农生物技术有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114350726-A | Method for synthesizing trehalose by taking cellulose as substrate | 华南理工大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-110628732-B | Herbicide tolerance protein, coding gene and application thereof | 北京大北农生物技术有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114364704-A | Modified PIGGYBAC transposase polypeptides, polynucleotides encoding them, introduction vectors, kits, methods of integrating target sequences into the genome of a cell, and methods of producing a cell | 株式会社东芝 | 2022-04-15 | — | — | CN | disclosed |
| CN-111718946-B | Codon-optimized lipase gene, engineering bacterium and textile application thereof | 中国科学院天津工业生物技术研究所 | 2022-04-15 | — | — | CN | disclosed |
| CN-111424047-B | 4, 6-alpha-glucosyltransferase and application thereof in production of resistant dextrin | 江南大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341179-A | Multimeric bispecific anti-CD 123 binding molecules and uses thereof | IGM生物科学股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-108633305-B | Immunoassay for diagnosing viral infection | 欧蒙医学实验诊断股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114306596-A | Topical application of anti-HSV antibodies | 海德堡免疫疗法有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341158-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114340682-A | Immune microbubble complexes and uses thereof | 艾姆戈特株式会社 | 2022-04-12 | — | — | CN | disclosed |
| CN-114317565-A | Starch branching enzyme from myxobacteria, gene thereof, engineering bacterium containing gene and application thereof | 南京农业大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114340671-A | Antibodies specific for GPC3 and methods of use thereof | R.P.谢勒技术有限责任公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114316067-A | Anti-cancer fusion polypeptides | 皮里斯制药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114317483-A | Monosaccharide kinase for catalytically generating L-arabinose-1-phosphate and coding gene and application thereof | 山东大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341178-A | Antibodies and detection of CCL14 | 机敏医药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341188-A | Antibodies that bind to cancer cells and target radionuclides to said cells | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341359-A | Abiotic stress tolerant plants and methods thereof | 未名生物农业集团有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112538105-B | Stable coronavirus spike (S) protein antigens and related vaccines | 斯克里普斯研究院 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341351-A | Strains and methods for producing hemoprotein | 非凡食品有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-113831394-B | Recombinant virus combination of African swine fever virus ASFV gene and vaccine prepared from recombinant virus combination | 中国人民解放军军事科学院军事医学研究院 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341180-A | Humanized antibodies against PD-L1 | 上海药明生物技术有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341356-A | Flowering phase genes and methods of use thereof | 未名生物农业集团有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341344-A | Engineered microorganisms and methods for improving aldehyde dehydrogenase activity | 基因组股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114317730-A | Application of TTPAL as gastric cancer monitoring or prognosis judgment marker | 香港中文大学深圳研究院 | 2022-04-12 | — | — | CN | disclosed |
| CN-113521276-B | Liquid formulations comprising anti-human interferon alpha receptor 1(IFNAR1) monoclonal antibodies | 江苏荃信生物医药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-109486852-B | Use of insecticidal proteins | 北京大北农生物技术有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114306593-A | Methods for inhibiting fibrosis in a subject in need thereof | 莱斯特大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114341159-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114317471-A | Means and methods for detoxifying mycotoxins | 艾尔柏股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114315982-A | Novel phage lysin LysDLn1 and application thereof | 暨南大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114316062-A | Multispecific antibody targeting HIV gp120 protein and human CD3 molecule and application thereof | 珠海臻谱基因科技有限公司北京分公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-113150093-B | Loquat flowering inhibitor EjFLC gene and encoding protein and application thereof | 西南大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114316045-A | anti-PD-L1 antibodies and uses thereof | 锋宏生物医药科技(昆山)有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114340679-A | Methods and medicaments for treating cancers that are non-responsive to inhibitors of PD-1/PD-L1 signaling | 基因泰克公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-109959788-B | Coating antigen and enzyme-labeled antibody for detecting porcine pseudorabies virus gE antibody and blocking method kit | 洛阳普泰生物技术有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-114292824-A | Construction method and application of recombinant chimeric newcastle disease virus expressing chicken infectious bursal disease virus variant VP2 gene | 河南农业大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-114292330-A | Antibody molecules that bind CD45 | UCB生物制药有限责任公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-114302963-A | Flowering phase genes and methods of use thereof | 未名生物农业集团有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-114292331-A | Anti-human BDCA-2 antibody, method for producing same, polynucleotide, expression vector, host cell and pharmaceutical composition | 安斯泰来制药株式会社 | 2022-04-08 | — | — | CN | disclosed |
| CN-113234154-B | Rheumatoid factor IgG, IgM and IgA composite quality control product and preparation method and application thereof | 四川携光生物技术有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-114302962-A | TCR constructs specific for EBV-derived antigens | 马克思-德布鲁克-分子医学中心亥姆霍兹联合会 | 2022-04-08 | — | — | CN | disclosed |
| CN-110724182-B | Marker combination for improving detection sensitivity of bacterial scrotum infection and application thereof | 上海交通大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-114292324-A | Strain for producing alpha-lactalbumin by co-expressing chaperone protein and application thereof | 江南大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-114292823-A | Recombinant LaSota vaccine strain carrying genes VII type Newcastle disease virus F and HN genes and construction method and application thereof | 河南农业大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-110028564-B | Rice salt-tolerant transcription factor OsC3H38 and coding gene and application thereof | 河北师范大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-112904017-B | Detection system based on covalent connection for interaction between known molecules and proteins and identification or verification method thereof | 上海交通大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-110194790-B | Plant immune activator protein FoPII1 secreted by fusarium oxysporum and application thereof | 南京农业大学 | 2022-04-08 | — | — | CN | disclosed |
| CN-111961126-B | Application of TaVQ25 gene in regulation and control of resistance of wheat to powdery mildew and banded sclerotial blight | 中国农业科学院作物科学研究所 | 2022-04-08 | — | — | CN | disclosed |
| WO-2022072469-A1 | COMPOSITIONS FOR INHIBITING VIRAL ENTRY AND METHODS USING SAME | DREXEL UNIVERSITY (US) | 2022-04-07 | — | — | WO | disclosed |
| CN-114277022-A | Nitrile hydratase mutant with high activity and high thermal stability | 江南大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-111333708-B | Gene derived from corn and having function of delaying flowering phase and application thereof | 广西大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-112940124-B | Humanized monoclonal antibody targeting Claudin18.2 and preparation method and application thereof | 南京凯地医疗技术有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-112028994-B | Antibody for resisting staphylococcus aureus enterotoxin B, detection test paper and kit | 北京弘进久安生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-114277045-A | Construction and application of amide compound biosensor | 江南大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-114272371-A | Combination therapy comprising anti-PD-1 antibody molecules | 诺华股份有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-111808193-B | Nanobody capable of binding human CD38 and application thereof | 源道隆（苏州）医学科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-108138168-B | Linalool composition and preparation method thereof | 味之素株式会社 | 2022-04-05 | — | — | CN | disclosed |
| CN-114276459-A | Fusion peptides for forming viroid particles | 台湾中山大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-114277009-A | GTFB mutant and application thereof in preparation of a series of isomaltulose with different hydrolysis resistance | 江南大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-114269380-A | IgM sugar variants | IGM生物科学股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110093331-B | High-temperature-resistant wide-pH-stability mannase Man gold, gene and application | 武汉轻工大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-113150136-B | Preparation of novel coronavirus N protein monoclonal antibody | 杭州贤至生物科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110511272-B | Corn ZmbHLH55 transcription factor and application thereof | 南通大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269398-A | Method for isolating spider silk proteins by high shear solubilization | 保尔特纺织品公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114262379-A | PD-1/VEGF tetravalent bispecific antibody, preparation method and application thereof | 丹生医药技术(上海)有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-107002151-B | Method of delivering an analyte to a transmembrane pore | 牛津纳米孔技术公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114262377-A | Preparation method of anti-human CD70 nano antibody for blocking combination of CD70 and ligand CD27 thereof and coding sequence thereof | 新疆优迈生物技术有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110616203-B | Mutant p-hydroxyphenylpyruvate dioxygenase, nucleic acid encoding same and use thereof | 青岛清原化合物有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114264828-A | Biomarker for identifying benign thyroid nodule and thyroid cancer and application thereof | 中国科学院基础医学与肿瘤研究所(筹) | 2022-04-01 | — | — | CN | disclosed |
| CN-112500480-B | Nanobodies against novel coronaviruses and uses thereof | 上海洛启生物医药技术有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269376-A | Methods of treating cancer with anti-PD-L1 antibodies | 豪夫迈·罗氏有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114262688-A | Method for preparing age-characteristic-retaining inhibitory interneuron from non-nerve cell transformation | 宁波易赛腾生物科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-107921093-B | B7-H1 fusion polypeptides for the treatment and prevention of organ failure | 弗劳恩霍夫应用研究促进协会 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269947-A | Method | 牛津纳米孔科技公开有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269779-A | anti-BAG 2 antibodies and methods of treating cancer | 株式会社麦迪帕克特 | 2022-04-01 | — | — | CN | disclosed |
| CN-114264814-A | Antibody detection kit for PD-1 biological agent and preparation method thereof | 苏州和锐生物科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269781-A | Combination of bispecific fusion proteins with anti-Her 2 antibodies for tumor therapy | 江苏康宁杰瑞生物制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269908-A | Engineered trans-enoyl COA reductase and preparation method and using method thereof | 基因组股份公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269785-A | Immunostimulatory multimeric binding molecules | IGM生物科学股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-112673025-B | Chimeric antigen receptor containing third signal receptor and application thereof | 上海隆耀生物科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-111978400-B | Rift valley fever virus humanized monoclonal antibody and application thereof | 中国科学院微生物研究所 | 2022-04-01 | — | — | CN | disclosed |
| CN-112402597-B | FAP (FAP-modified exosome-like nano-vesicle tumor vaccine | 四川大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269767-A | System, method and composition for in vitro transcription and translation recombination using thermophilic proteins | 自然工具箱公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269765-A | Klebsiella vaccine and methods of use | 康奈尔大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269389-A | Antibody drug conjugates targeting claudin 18.2 | 礼新医药科技(上海)有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-111876396-B | Double-coenzyme-dependent glufosinate-ammonium dehydrogenase mutant and application thereof in catalytic synthesis of L-glufosinate-ammonium | 浙江工业大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-114258399-A | Protein container, polynucleotide, vector, expression cassette, cell, method for producing container, method for identifying pathogen or diagnosing disease, use of container, and diagnostic kit | 奥斯瓦道·克鲁兹基金会 | 2022-03-29 | — | — | CN | disclosed |
| CN-107840888-B | Mediterranean and mesomeric binding antibodies and uses thereof | 希望之城公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-114252618-A | Application of urine alpha-1-microglobulin/trypsin inhibitor precursor and polypeptide fragment thereof in allergic diseases | 张曼 | 2022-03-29 | — | — | CN | disclosed |
| CN-106459160-B | ASX-specific protein ligases | 南洋理工大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-114250205-A | 7 alpha-hydroxysteroid dehydrogenase mutant with high thermal stability and application thereof | 宋建芳 | 2022-03-29 | — | — | CN | disclosed |
| CN-108138362-B | Modular polypeptide libraries and methods of making and using the same | 加利福尼亚大学董事会 | 2022-03-29 | — | — | CN | disclosed |
| CN-114250219-A | Balsamiferol synthase mutant and application thereof | 天津科技大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-114258305-A | Type III NKT cells and related compositions and methods | 阿克索治疗公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-109069638-B | Trispecific inhibitors for cancer therapy | 璟尚生物制药公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-114250237-A | Tyrosine phenol lyase mutant, engineering bacteria and application of tyrosine phenol lyase mutant in catalytic synthesis of levodopa | 浙江工业大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-112898393-B | TaAOS gene and application of protein coded by same | 河南农业大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-113005113-B | Heat-resistant beta-mannase mutant ManAK-5 and coding gene and application thereof | 中国海洋大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-108040482-B | Composition for colon cleansing and treatment of gastrointestinal disorders | 硬木药品公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-114252607-A | Application of urine V-ATPASE subunit S1 and polypeptide fragment thereof in allergic diseases | 首都医科大学附属北京世纪坛医院 | 2022-03-29 | — | — | CN | disclosed |
| CN-111205371-B | Antibody for resisting lymphocyte activating gene 3 and application | 北京吉尔麦迪生物医药科技有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-114249825-A | Antibodies that bind human IL-33, methods of making, and uses thereof | 三生国健药业（上海）股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-111100194-B | Application of antibacterial peptide PD-L4 in inhibition of avian influenza virus | 佛山科学技术学院 | 2022-03-25 | — | — | CN | disclosed |
| CN-111534498-B | Cyclodextrin glucosyltransferase mutant with improved disproportionation specific activity and AA-2G yield | 江南大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-114231546-A | Neutral cellulase optimized gene and preparation method and application thereof | 武汉新华扬生物股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-112899258-B | Heat-resistant beta-mannase mutant ManAK-10 and coding gene and application thereof | 中国海洋大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-111087468-B | PRRSV broad-spectrum neutralizing monoclonal antibody 5D9 and application thereof | 西北农林科技大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-111138535-B | Immunopotentiator and application thereof in vaccine preparation | 西北农林科技大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-114245824-A | Plants and methods having increased abiotic stress tolerance | 未名生物农业集团有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-113005112-B | Heat-resistant beta-mannase mutant ManAK-9 and coding gene and application thereof | 中国海洋大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-114231605-A | Freeze-dried composition for nucleic acid amplification | 南京诺唯赞生物科技股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-108341873-B | Antibodies to epidermal growth factor receptor 3(HER3) | 诺华股份有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-107106662-B | Improved blood coagulation compositions | Q-塞拉有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-109608530-B | Soybean low-phosphorus response gene for promoting lateral root formation, protein and application thereof | 华南农业大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-114231489-A | Functional fragments for reprogramming, combinations and applications thereof | 纽伦捷生物医药科技（苏州）有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-112521473-B | Wheat male sterility related protein TaMYB97, and coding gene and application thereof | 北京市农林科学院 | 2022-03-25 | — | — | CN | disclosed |
| US-20220089579-A1 | BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS | UNIV YALE (US) | 2022-03-24 | — | — | US | disclosed |
| CN-112159480-B | Chicken infectious bursal disease virus multi-antigen epitope protein and application thereof | 福建农林大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-112941055-B | Heat-resistant beta-mannase mutant ManAK-4 and coding gene and application thereof | 中国海洋大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-107109370-B | Recombinant glycoproteins sialylated with O-glycans and cell lines for the production thereof | 塞维克制药有限责任公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-109021116-B | Chimeric antigen receptor for anti-BCMA antigen and application thereof | 重庆精准生物技术有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-112048011-B | Method for improving salt tolerance of rice | 南昌大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-107810193-B | Novel peptides and peptide compositions and scaffolds thereof for immunotherapy of colorectal cancer (CRC) and other cancers | 伊玛提克斯生物技术有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114214339-A | Hemp THCSAS2 gene, terpene phenolic acid oxidative cyclase as coded product thereof and application of terpene phenolic acid oxidative cyclase | 福建农林大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-114222821-A | Microorganism having enhanced L-threonine-producing ability and method for producing threonine using the same | CJ第一制糖株式会社 | 2022-03-22 | — | — | CN | disclosed |
| CN-110894220-B | Application of seed-related protein in regulating and controlling plant seed size | 中国科学院遗传与发育生物学研究所 | 2022-03-22 | — | — | CN | disclosed |
| CN-114214398-A | Mutant FBN1 gene and marfan syndrome detection kit | 百世诺(北京)医学检验实验室有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114214299-A | M-MLV reverse transcriptase and preparation method thereof | 苏州译酶生物科技有限公司 | 2022-03-22 | — | — | CN | disclosed |
| US-11279959-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2022-03-22 | — | — | US | disclosed |
| CN-111434679-B | Application of plant type related protein in regulation and control of plant type | 中国科学院遗传与发育生物学研究所 | 2022-03-22 | — | — | CN | disclosed |
| CN-114196655-A | Heat-resistant Kunmu polysaccharide degrading enzyme OUC-SaLam66 and application thereof | 中国海洋大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195897-A | PD-L1 monoclonal antibody, heavy chain and light chain variable regions, monoclonal cell strain, application and kit | 广州兆瑞医学生物科技有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114207108-A | Genetically modified host cells producing glycosylated cannabinoids | 奥克塔林生物制剂公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-107922492-B | Antibody molecules that bind CD79 | UCB生物制药有限责任公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206907-A | anti-VEGF protein composition and preparation method thereof | 瑞泽恩制药公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206925-A | anti-VEGF protein composition and preparation method thereof | 瑞泽恩制药公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206914-A | anti-VEGF protein composition and preparation method thereof | 瑞泽恩制药公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195894-A | Antibody targeting 4-1BB and application thereof | 普米斯生物技术(珠海)有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114199848-A | High-throughput protein expression detection method based on protein ligase | 无锡佰翱得生物科学有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113248618-B | anti-PD-L1/anti-LAG 3 bispecific antibodies and uses thereof | 天境生物科技(杭州)有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206946-A | Coronavirus vaccine compositions, methods and uses thereof | 四川三叶草生物制药有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195900-A | Anti-4-1 BB/PD-L1 bispecific antibody and application thereof | 普米斯生物技术(珠海)有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206924-A | anti-VEGF protein composition and preparation method thereof | 瑞泽恩制药公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206939-A | Dosage regimen for administration of LAG-3/PD-L1 bispecific antibodies | F-星治疗有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-113004386-B | Grass carp anaphylactic toxin C5a recombinant protein and polyclonal antibody thereof | 湖南农业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-114196642-A | Glutamate dehydrogenase variants and their use in the preparation of L-amino acids | 浙江大学杭州国际科创中心 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195901-A | Bispecific recombinant proteins and uses thereof | 上海霖羲致企业管理有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206372-A | Pharmaceutical formulations of unactivated polypeptide TRP | 大都会生命科学有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-111304270-B | Method for producing maltodextrin with single polymerization degree by multi-enzyme coupling | 江南大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-111004311-B | Plant storage protein synthesis related protein F690 and coding gene and application thereof | 中国农业科学院作物科学研究所 | 2022-03-18 | — | — | CN | disclosed |
| CN-114206371-A | Klebsiella for controlling Klebsiella | 诺麦生物科学有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-111848756-B | Insect-resistant protein mVIP3An18, coding gene and application | 九圣禾种业股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| WO-2022056200-A1 | METHODS AND COMPOSITIONS FOR POTENTIATING ANTITUMORAL IMMUNE RESPONSES THROUGH TARGETING OF NTPDASE3 | Purinomia Biotech, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |
| US-20220081474-A1 | Nucleic Acids for Treatment of Allergies | Immunomic Therapeutics, Inc (US) | 2022-03-17 | — | — | US | disclosed |
| CN-111876431-B | Rice OsSDY1 gene, biological material, method, expression vector transformation host and application thereof in stress resistance and stable yield | 武汉大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-107864654-B | Novel peptides and peptide compositions for immunotherapy and methods for the generation of scaffolds for pancreatic and other cancers | 伊玛提克斯生物技术有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-113214358-B | Short peptide, detection kit and method for detecting vascular endothelial growth factor | 青岛大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-113004383-B | Application of corn gene ZmEREB102 in improving corn yield | 华中农业大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-108546300-B | Molecules that bind EGFR and C-MET fibronectin type III domain | 詹森生物科技公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-113201512-B | Inulin sucrase mutant for producing kestose | 江南大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-111333723-B | Monoclonal antibody aiming at rabies virus G protein and application thereof | 北京智仁美博生物科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-114181306-A | Bovine-derived single-chain antibody for resisting staphylococcus aureus virulence factor Hlb, preparation method and application | 上海交通大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-111333724-B | Monoclonal antibody YG11-1 for resisting staphylococcus aureus enterotoxin B and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-03-15 | — | — | CN | disclosed |
| CN-108137676-B | gp120 neutralizing antibodies and uses thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2022-03-15 | — | — | CN | disclosed |
| CN-112592392-B | Application of pleiotropic gene SbSnf4 in improvement of cane sugar yield, plant height, fresh weight of stems and/or juice amount | 安徽科技学院 | 2022-03-15 | — | — | CN | disclosed |
| CN-112608371-B | Pleiotropic gene SbSnf4 and application thereof in improving sugar content and biological yield of sorghum stalks | 安徽科技学院 | 2022-03-15 | — | — | CN | disclosed |
| CN-112266907-B | Sclerotium rolfsii endogenous sclerotium rolfsii hydrolase and application thereof | 江南大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-114181310-A | anti-TIGIT antibody, and pharmaceutical composition and use thereof | 中山康方生物医药有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-113215125-B | Inulin sucrase mutant with improved thermal stability and enzyme activity | 江南大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-109072246-B | Microorganism for producing putrescine and method for producing putrescine by using same | CJ第一制糖株式会社 | 2022-03-15 | — | — | CN | disclosed |
| CN-114174321-A | Modified S2 subunit of coronavirus spike protein | 勃林格殷格翰动物保健有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114174518-A | Abiotic stress tolerant plants and methods | 未名生物农业集团有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114173813-A | anti-B7-H3 antibodies and methods of use thereof | 晶体生物科学股份有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-110628750-B | Beta-1, 3-1, 4-glucan glucohydrolase and application thereof | 广西大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-110982891-B | Paroxysmal supraventricular tachycardia screening kit | 四川省人民医院 | 2022-03-11 | — | — | CN | disclosed |
| CN-111434687-B | Antibody and application thereof | 南京赛新生物科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114173823-A | Use of anti-CEACAM 5 immunoconjugates for treating lung cancer | 赛诺菲 | 2022-03-11 | — | — | CN | disclosed |
| CN-107253992-B | Monoclonal antibody against HER2 | 根马布股份公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114174517-A | Biotic stress tolerant plants and methods | 未名生物农业集团有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114163531-A | Tissue factor pathway inhibitor antibodies and uses thereof | 辉瑞公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114174519-A | Method for producing enzyme composition comprising recombinant endopeptidase | 内米西斯有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114174829-A | Selection of T cell receptors | 磨石生物公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111995683-B | anti-PD-L1 protein monoclonal antibody, cell strain, preparation method and application thereof | 福州迈新生物技术开发有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114164129-A | Recombinant pichia pastoris for heterologous expression of myrosinase and application of recombinant pichia pastoris in preparation of sulforaphane | 江南大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-114174331-A | Antibodies that bind human metapneumovirus fusion proteins and uses thereof | 佐治亚大学研究基金会有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114163532-A | Chimeric antigen receptor comprising novel costimulatory domains and uses thereof | 南京北恒生物科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2022049409-A1 | EXPRESS DIAGNOSTICUM FOR SARS-COV-2 | SIA TERRAGEN (LV) | 2022-03-10 | — | — | WO | disclosed |
| EP-3072527-B1 | IMMUNOSUPPRESSANT | UNIV HOKKAIDO NAT UNIV CORP (JP) | 2022-03-09 | — | — | EP | disclosed |
| CN-112029780-B | Salvia miltiorrhiza transcription factor SmNAC78 gene and application of expression vector thereof | 广州中医药大学(广州中医药研究院) | 2022-03-08 | — | — | CN | disclosed |
| CN-112513095-B | HER3 antigen binding molecules | 蜂鸟生物科技控股有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-109806388-B | Immunomodulatory vaccines | S-目标疗法有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-107828671-B | Compositions and methods for producing 3-hydroxypropionic acid | 卡吉尔公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-114149502-A | Antibody of alpha 3, detection kit and application of antibody | 杭州百凌生物科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-108513615-B | Antibodies that bind to the human cannabinoid 1(CB1) receptor | 鸟石生物公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-111995681-B | anti-TIGIT antibody, preparation method and application thereof | 华博生物医药技术（上海）有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-112280722-B | Recombinant bacterium for producing optically pure 1, 3-butanediol and application thereof | 清华大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-110950956-B | Polypeptide capable of binding PD1 and application thereof | 源道隆（苏州）医学科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-114129708-A | Application of INVS (insulin-dependent versus-insulin-dependent) protein in preparation of drug for repairing heavy metal-induced testicular injury | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 2022-03-04 | — | — | CN | disclosed |
| CN-114144527-A | Expression of nitrogenase polypeptides in plant cells | 联邦科学技术研究组织 | 2022-03-04 | — | — | CN | disclosed |
| CN-111154740-B | Husky microvesicle bacterium beta-galactosidase and coding gene and application thereof | 中国农业大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-109806387-B | Immunomodulatory vaccines | S-目标疗法有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-108472364-B | anti-CD 43 antibodies and their use in cancer therapy | 阿普洛根医药株式会社 | 2022-03-04 | — | — | CN | disclosed |
| CN-109666682-B | Rice serine hydroxymethyl transferase coding gene OsSHM4 mutant and application thereof | 南京农业大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-109154111-B | Yarn for cell culture scaffold, and cell culture scaffold fabric comprising same | 阿莫生命科学有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-112702927-B | Method and product for promoting smoker to switch to tobacco heating product or electronic cigarette | 卡巴斯有限责任公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-114144519-A | Single base replacement proteins and compositions comprising the same | 株式会社图尔金 | 2022-03-04 | — | — | CN | disclosed |
| CN-112301015-B | Method for promoting extracellular expression of protein in bacillus subtilis by using cutinase | 江南大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-113527496-B | anti-Trop 2 nano antibody and application thereof | 上海洛启生物医药技术有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-108026152-B | Cyclic RGD cell binding motifs and uses thereof | 思百博技术股份公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114107274-A | Preparation method of wool immobilized enzyme and wool immobilized enzyme column reactor | 厦门大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-114107243-A | Methionine adenosyltransferase mutant | 江南大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-114106111-A | High-adhesion polypeptide and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-03-01 | — | — | CN | disclosed |
| CN-114107269-A | Modification and application of nitrile hydratase amino acid motif | 江南大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-114099660-A | Trivalent gene engineering subunit vaccine composition for preventing duck infectious serositis and preparation method thereof | 扬州优邦生物药品有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114099423-A | Preparation of targeting CD47 and PD-L1 bifunctional fusion protein | 泰州迈博太科药业有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114106174-A | Low toxicity anti-OX 40 antibodies, pharmaceutical compositions and uses thereof | 苏州景涞医疗科技有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113527490-B | Preparation method of anti-human IFNAR1 monoclonal antibody concentrated solution | 江苏荃信生物医药股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114107275-A | Enzyme immobilization carrier and preparation method thereof, immobilized enzyme and preparation method thereof | 辽宁凯莱英医药化学有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114127120-A | Anti-carbonic anhydrase IX antibodies | 纳维再生科技股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114126645-A | Modified S1 subunit of coronavirus spike protein | 勃林格殷格翰动物保健有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114106182-A | Antibodies against TIGIT and uses thereof | 中山康方生物医药有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114126646-A | Sequence-based high throughput method for generating camelid antibodies to cover broad epitopes with high resolution | 浙江纳米抗体技术中心有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114107340-A | Mevalonate kinase gene RKMK and application thereof | 昆明理工大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-114127305-A | Ligand discovery and gene delivery via retroviral surface display | 麻省理工学院 | 2022-03-01 | — | — | CN | disclosed |
| CN-114107457-A | Method of delivering an analyte to a transmembrane pore | 牛津纳米孔技术公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-111349640-B | Trans-4-hydroxy-L-proline production strain and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-03-01 | — | — | CN | disclosed |
| CN-114107255-A | Panax japonicus glycoside hydrolase and application thereof in production of zingiber officinale-shaped notoginsenoside R1 | 上海中医药大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-108026170-B | anti-CD 71 antibodies, activatable anti-CD 71 antibodies, and methods of use thereof | 西托姆克斯治疗公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-110029122-B | Mannase high-yield strain and application thereof | 青岛蔚蓝生物集团有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-110804634-B | Process for preparing 2,4-diaminobutyric acid by enzyme catalysis method | 深圳瑞德林生物技术有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-107001419-B | Neurodegenerative disorders | 神经生物有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114085845-A | Gene related to nicotine metabolism of tobacco and application thereof | 云南中烟工业有限责任公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114096672-A | WOX gene | 先正达农作物保护股份公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114085800-A | Novel isopropylmalate synthase variants and method for producing L-leucine using same | CJ第一制糖株式会社 | 2022-02-25 | — | — | CN | disclosed |
| CN-114085849-A | Herbicide resistance protein, gene and use | 青岛清原化合物有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114096563-A | Antibodies that specifically bind to B7-H3 and uses thereof | Y生物股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-107207579-B | Antigen binding molecules comprising trimeric TNF family ligands | 豪夫迈·罗氏有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114073775-A | Combination therapy for delivery across the blood brain barrier | 比奥阿赛斯技术有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-114073760-A | Application of RDR protein in tumor treatment | 北京大学 | 2022-02-22 | — | — | CN | disclosed |
| CN-109456393-B | Application of streptococcus pneumoniae protein in resisting streptococcus pneumoniae infection | 重庆医科大学 | 2022-02-22 | — | — | CN | disclosed |
| CN-114075288-A | anti-PD-L2 antibody | 正大天晴药业集团股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-111808179-B | Phytophthora sojae 4 NCR protein and its coding gene and application | 中国农业大学 | 2022-02-22 | — | — | CN | disclosed |
| CN-111154735-B | Preparation method of ketene reductase and brivaracetam intermediate | 宁波酶赛生物工程有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-114075559-A | Type 2 CRISPR/Cas9 gene editing system and application thereof | 珠海舒桐医疗科技有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-114075550-A | Engineered immune cells and uses thereof | 南京北恒生物科技有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-114057855-A | Protein for aphid falling caused by high temperature and application thereof | 中国农业科学院深圳农业基因组研究所 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057877-A | anti-PD-L1 antibody and application thereof | 百奥泰生物制药股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-107912043-B | Novel peptides and peptide compositions for immunotherapy of esophageal and other cancers | 伊玛提克斯生物技术有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114053396-A | Application of INVS protein in preparation of medicine for repairing damage of testicular supporting cells | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 2022-02-18 | — | — | CN | disclosed |
| CN-114057879-A | PD-L1 monoclonal antibody, heavy chain and light chain variable regions, monoclonal cell strain, application and kit | 广州兆瑞医学生物科技有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114072423-A | Combination therapy involving anti-CD 39 antibodies and anti-PD-1 or anti-PD-L1 antibodies | 翠舒拉治疗股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114072673-A | Cell-based methods for determining botulinum toxin activity | 秀杰股份公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114072168-A | Chimeric Zika-Japanese encephalitis virus | 勒芬天主教大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-114058560-A | Method for producing glycine | 中国科学院天津工业生物技术研究所 | 2022-02-18 | — | — | CN | disclosed |
| CN-114058633-A | Hydrolase gene strH and protein coded by same and application | 南京农业大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-114058601-A | Enzyme with function of catalyzing glycolaldehyde to synthesize ethylene glycol and application thereof | 北京化工大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-113215109-B | Construction of African swine fever polygene combined deletion attenuated strain and application of attenuated strain as vaccine | 中国农业科学院兰州兽医研究所 | 2022-02-18 | — | — | CN | disclosed |
| CN-114072508-A | Novel lactic acid bacterium | 杜邦营养生物科学有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-112391393-B | Application of Zmcps gene in preparation of male sterile line of corn | 吉林省农业科学院 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057878-A | Affinity purification method for reducing content of host cell protein in monoclonal antibody production | 江苏荃信生物医药股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114072677-A | Reagents and methods for cancer detection, prognosis and therapy monitoring | 美国桑福德医疗集团 | 2022-02-18 | — | — | CN | disclosed |
| CN-114045277-A | Base editor and construction method and application thereof | 复旦大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-114045305-A | Multi-swivel subsystem | 深圳市深研生物科技有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-113308427-B | Genetically engineered bacterium capable of efficiently adsorbing lead ions and application thereof | 江南大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-109470858-B | Protein chip and kit for lung cancer diagnosis | 广州市丹蓝生物科技有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-114045230-A | Actinomycetes for promoting plant root growth and application thereof | 中国农业科学院农业环境与可持续发展研究所 | 2022-02-15 | — | — | CN | disclosed |
| US-11248201-B2 | Cell culture vessel | AMOLIFESCIENCE CO., LTD. (KR) | 2022-02-15 | — | — | US | disclosed |
| CN-108064277-B | Novel thermolysin-derived keratinase and use thereof | 庆北大学校产学协力团 | 2022-02-11 | — | — | CN | disclosed |
| CN-108350412-B | Method for producing aldehyde | 味之素株式会社 | 2022-02-11 | — | — | CN | disclosed |
| CN-107406864-B | Method for producing L-serine using genetically engineered microorganisms lacking serine degradation pathway | 化学生物有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-112063610-B | Tyrosine phenol lyase mutant, engineering bacterium and application | 浙江工业大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-114040927-A | Polypeptide binding to CD33 and application thereof | 印希比股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114040971-A | CRISPR-Cas effector polypeptides and methods of use thereof | 加利福尼亚大学董事会 | 2022-02-11 | — | — | CN | disclosed |
| CN-114040800-A | Killer cell lectin-like receptor subfamily G member 1(KLRG1) depleting antibodies | 阿波科有限责任公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-107750166-B | PD-L1 antagonist combination therapy | 默克专利股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-107208088-B | Oleic acid production in yeast | 银杏生物制品公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114031686-A | Antibody of alpha 5 collagen IV, detection kit and application thereof | 杭州百凌生物科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-108603179-B | Eukaryotic cells with increased production of fermentation products | 帝斯曼知识产权资产管理有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-114026239-A | MUT-methanol nutritional yeast | 维也纳自然资源与生命科学大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-109266664-B | Method for improving stability of glutamate oxidase by using fusion truncated expression strategy | 南京工业大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-114015665-A | Engineered NADPH-dependent phenylglycine dehydrogenase and application thereof | 中山大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-114026116-A | RAS neoantigen specific binding proteins and uses thereof | 弗雷德哈钦森癌症研究中心 | 2022-02-08 | — | — | CN | disclosed |
| CN-114026226-A | Target-specific CRISPR mutants | 株式会社图尔金 | 2022-02-08 | — | — | CN | disclosed |
| WO-2022023964-A1 | P53 POST-TRANSLATIONAL MODIFICATIONS AS MARKERS IN THE DIAGNOSIS AND PROGNOSIS OF A NEURODEGENERATIVE DISEASE | DIADEM S.R.L. (IT) | 2022-02-03 | — | — | WO | disclosed |
| US-20220034912-A1 | p53 POST-TRANSLATIONAL MODIFICATIONS AS MARKERS IN THE DIAGNOSIS AND PROGNOSIS OF A NEURODEGENERATIVE DISEASE | DIADEM S.R.L. (IT) | 2022-02-03 | — | — | US | disclosed |
| CN-113999319-A | GPC 3-targeted chimeric antigen receptor expressing PD-L1 single-chain antibody, T cell, preparation method and application | 深圳先进技术研究院 | 2022-02-01 | — | — | CN | disclosed |
| CN-113999807-A | Construction method of recombinant strain and application of recombinant strain in production of itaconic acid | 南京工业大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-113999863-A | Method for improving water utilization efficiency of tomato crops | 浙江大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-113999857-A | Gene related to tobacco nicotine synthesis regulation and control and application thereof | 云南中烟工业有限责任公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-111733152-B | Escherichia coli expressing inclusion body of activity of tyrosine phenol lyase and application of escherichia coli | 江南大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-114008197-A | Metabolic engineering for simultaneous consumption of xylose and glucose to produce chemicals from second generation sugars | 布拉斯科公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-109196151-B | Yarn for cell culture scaffold, twisted yarn comprising same, and fabric comprising same | 阿莫绿色技术有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-111394410-B | High-catalytic-activity neuraminic acid synthase and application thereof | 江南大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-110713997-B | Agarase with uniform degradation products and application thereof | 江南大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-113980922-A | Recombinant lipoxygenase, induction expression method and application thereof | 广东省农业科学院蚕业与农产品加工研究所 | 2022-01-28 | — | — | CN | disclosed |
| CN-113975285-A | Application of GGPP (gas-gas phase plasma) combination and allosteric activation of humanized FBP1 in preparation of anti-hepatocellular carcinoma drugs | 南京大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113980939-A | Glucose-resistant beta-glucosidase, and expression gene and application thereof | 海南大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113993898-A | Human antibodies that bind RET and methods of use thereof | 瑞泽恩制药公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-107074948-B | Antibodies that bind AXL | 根马布股份公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-113980948-A | High-activity tyrosine phenol lyase mutant | 天津大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113980932-A | Site-directed mutagenesis alpha-glucosidase | 暨南大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-113502255-B | Engineered microorganisms for the production of olivetol and olivetol | 北京蓝晶微生物科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| CN-111856024-B | Method for detecting interaction between biological membrane proteins and kit used in method | 清华大学 | 2022-01-28 | — | — | CN | disclosed |
| US-20220025021-A1 | ANTIBODY THERAPIES FOR HUMAN IMMUNODEFICIENCY VIRUS (HIV) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2022-01-27 | — | — | US | disclosed |
| CN-113969269-A | D-amino acid oxidase mutant and application thereof in preparation of L-glufosinate-ammonium | 永农生物科学有限公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-113969268-A | Glu/Leu/Phe/Val dehydrogenase mutant and application thereof in preparation of L-glufosinate-ammonium | 永农生物科学有限公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-107429255-B | Methods for introducing multiple expression constructs into eukaryotic cells | 诺维信公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-113967195-A | anti-HER 2/PD1 bispecific antibody lyophilized preparation and preparation method thereof | 三生国健药业（上海）股份有限公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-107847592-B | Antibodies against human CSF-1R for inducing lymphocytosis in lymphomas or leukemias | 豪夫迈·罗氏有限公司 | 2022-01-21 | — | — | CN | disclosed |
| CN-113957088-A | Artificial design and application of intercellular communication system | 中国科学院微生物研究所 | 2022-01-21 | — | — | CN | disclosed |
| CN-113957061-A | Administration of kynurenine depleting enzymes for tumor therapy | 得克萨斯大学体系董事会 | 2022-01-21 | — | — | CN | disclosed |
| CN-110470779-A | The method for building up and its finger-print of four taste treasure's layer ice boron eye drops finger-print | JIANGXI ZHENSHIMING PHARMACEUTICAL CO LTD | 2019-11-19 | — | — | CN | disclosed |
| US-7632818-B2 | Method for treating conditions associated with the Metabolic Syndrome (Syndrome X) | GOTTLIEB MARISE S | 2009-12-15 | — | — | US | disclosed |
| US-7419776-B1 | Method of reducing pathogen load | GOTTLIEB LEGAL REPRESENTATIVE | 2008-09-02 | — | — | US | disclosed |
| CN-100333787-C | YG and YGG for use as medicaments for maintaining and improving immune response | GAUTRIBE M (US) | 2007-08-29 | — | — | CN | disclosed |
| WO-2006097774-A1 | SYNTHETIC PEPTIDES CONTAINING UNNATURAL ADAMANTANE-RELATED AMINO ACIDS FOR USE AS ANTITUMOUR DRUGS | RUDJER BOSKOVIC INSTITUTE (HR) | 2006-09-21 | — | — | WO | disclosed |
| CN-1644214-A | YG and YGG for use as medicaments for maintaining and improving immune response | GAUTRIBE M (US) | 2005-07-27 | — | — | CN | disclosed |
| US-20040186059-A1 | Method for treating conditions associated with the Metabolic Syndrome (Syndrome X) | GOTTLIEB MARISE S (US) | 2004-09-23 | — | — | US | disclosed |
| WO-2000068695-A2 | REAGENT AND PROCESS FOR PEPTIDE/PROTEIN DIFFERENTIATION USING CIRCULAR DICHROISM DETECTION | UNIV OKLAHOMA STATE (US) | 2000-11-16 | — | — | WO | disclosed |
| EP-0597838-B1 | VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE INC (CA) | 1998-12-02 | — | — | EP | disclosed |
| US-5773007-A | BACTERIA POLYSACCHARIDE PROTEIN COMPLEX | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1998-06-30 | — | — | US | disclosed |
| EP-0609255-B1 | METHOD AND COMPOSITION FOR DETERMINING THE IMMUNOLOGICAL ACTIVITY OF BIOACTIVE SUBSTANCES | TORF ETS (LI) | 1997-05-28 | — | — | EP | disclosed |
| EP-0549617-B1 | IMPROVED VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE INC (CA) | 1996-03-27 | — | — | EP | disclosed |
| EP-0597838-A1 | VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE, INC. (CA) | 1994-05-25 | — | — | EP | disclosed |
| EP-0230052-B1 | Immunoamplifiers and related Compositions | GOTTLIEB ARTHUR A (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0549617-A1 | IMPROVED VACCINE COMPOSITIONS. | NORTH AMERICAN VACCINE INC (CA) | 1993-07-07 | — | — | EP | disclosed |
| EP-0522203-A1 | Protein from lactic acid bacteria | PROBICOM RESEARCH B.V. (NL) | 1993-01-13 | — | — | EP | disclosed |
| EP-0238851-B1 | A METHOD AND MEANS OF ASSAYING AN IMMUNE SYSTEM | Imreg, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |
| WO-1992004915-A1 | IMPROVED VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE, INC. (CA) | 1992-04-02 | — | — | WO | disclosed |
| US-5100663-A | Tyrosine-glycine dipeptide immune system stimulant useful in AIDS treatment | IMREG, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| US-5093321-A | Dialysates for treating aids and arc and for otherwise increasing immune response | IMREG, INC. (US) | 1992-03-03 | — | — | US | disclosed |
| US-5081108-A | Method of showing progression of AIDS in an ARC patient by treating with Tyr-Gly compositions | IMREG, INC. (US) | 1992-01-14 | — | — | US | disclosed |
| WO-1991016926-A1 | VACCINE COMPOSITIONS | NORTH AMERICAN VACCINE, INC. (CA) | 1991-11-14 | — | — | WO | disclosed |
| US-4906615-A | Substituted dipeptides as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0103077-B1 | SUBSTITUTED DIPEPTIDES, METHODS FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, METHOD FOR MAKING SUCH PHARMACEUTICAL COMPOSITIONS | SCHERING CORPORATION (US) | 1988-05-18 | — | — | EP | disclosed |
| US-4721726-A | ANALGESICS | SCHERING CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| EP-0238851-A2 | A method and means of assaying an immune system | Imreg, Inc. (US) | 1987-09-30 | — | — | EP | disclosed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| US-4610816-A | ANALGESICS | SCHERING CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0077274-B1 | 3-AMINO-2-HYDROXY-4-PHENYLBUTANOIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-08-28 | — | — | EP | disclosed |
| US-4474764-A | ANALGESICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |
| EP-0066956-B1 | ENKEPHALINASE ENZYME INHIBITING COMPOUNDS | PFIZER INC. (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0103077-A2 | Substituted dipeptides, methods for their production, pharmaceutical compositions containing them, method for making such pharmaceutical compositions | SCHERING CORPORATION (US) | 1984-03-21 | — | — | EP | disclosed |
| EP-0077274-A1 | 3-Amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-04-20 | — | — | EP | disclosed |
| EP-0066956-A1 | Enkephalinase enzyme inhibiting compounds | PFIZER INC. (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4329495-A | USEFUL AS ANALGESICS OR ANTICONVULSANTS, CHIRAL 2-(2-BENZYL-3-MERCAPTOPROPIONYLAMINO)-THIOBUTYRIC ACIDS, OR ALKANOL DERIVATIVES | PFIZER INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4051025-A | Preparative countercurrent chromatography with a slowly rotating helical tube array | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1977-09-27 | — | — | US | disclosed |
| US-4051025-A | Preparative countercurrent chromatography with a slowly rotating helical tube array | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1977-09-27 | — | — | US | disclosed |