SCHEMBL4405078

SCHEMBL4405078

C=CCOC(=O)C(=C)C1([SiH3])CCCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5672242 0.83
SCHEMBL27584891 0.82 ALDH1A1 (0.34)
SCHEMBL28665336 0.81
SCHEMBL28173078 0.81
SCHEMBL28665208 0.79 TSHR (0.33)
SCHEMBL20955910 0.78 TSHR (0.45)
SCHEMBL28072143 0.78
SCHEMBL2289336 0.77 ALDH1A1 (0.36)
SCHEMBL28318688 0.76
SCHEMBL5674947 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3470095-A1 INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF Universidade do Minho (PT) 2019-04-17 EP claimed
US-20060008506-A1 Method for preparing therapeutic ophthalmic articles using compressed fluids UNIVERSIDADE DE COIMBRA (PT) 2006-01-12 US claimed
EP-1611877-A1 Method for preparing sustained-release therapeutic ophthalmic articles using compressed fluids for impregnation of drugs Universidade de Coimbra (PT) 2006-01-04 EP claimed
US-11642439-B2 Injectable and expandable composition, devices, kits, methods and uses thereof UNIVERSIDADE DO MINHO (PT) 2023-05-09 US disclosed
US-20210187159-A1 INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEERING AND CELL BASED TECHNOLOGIES & THERAPIES (A4TEC) - ASSOCIAÇÃO (PT) 2021-06-24 US disclosed
EP-3743122-A1 INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF Universidade do Minho (PT) 2020-12-02 EP disclosed
WO-2019073463-A1 INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF UNIVERSIDADE DO MINHO (PT) 2019-04-18 WO disclosed
EP-3470095-A1 INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF Universidade do Minho (PT) 2019-04-17 EP disclosed
EP-1671124-A4 FILM LAYER FOR DETECTION OF IMMOBILIZED ANALYTES ZYOMYX INC (US) 2009-03-04 EP disclosed
EP-1671124-A1 FILM LAYER FOR DETECTION OF IMMOBILIZED ANALYTES Zyomyx, Inc. (US) 2006-06-21 EP disclosed
US-20060008506-A1 Method for preparing therapeutic ophthalmic articles using compressed fluids UNIVERSIDADE DE COIMBRA (PT) 2006-01-12 US disclosed
EP-1611877-A1 Method for preparing sustained-release therapeutic ophthalmic articles using compressed fluids for impregnation of drugs Universidade de Coimbra (PT) 2006-01-04 EP disclosed
WO-2005022151-A1 FILM LAYER FOR DETECTION OF IMMOBILIZED ANALYTES ZYOMYX, INC. (US) 2005-03-10 WO disclosed
US-20050048493-A1 Film layer for detection of immobilized analytes ZYOMYX, INC. (US) 2005-03-03 US disclosed
US-4182822-A VINYL AMIDES, ESTERS OF SILANE COMPOUNDS, CONTACT LENSES CHANG SING HSIUNG 1980-01-08 US disclosed