⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405078 | 0.83 | — | — | |
| SCHEMBL11132397 | 0.78 | NPSR1 (0.30) | — | |
| SCHEMBL5674947 | 0.76 | — | — | |
| SCHEMBL28072143 | 0.73 | — | — | |
| SCHEMBL1079279 | 0.73 | — | — | |
| SCHEMBL29220303 | 0.70 | TSHR (0.44) | — | |
| SCHEMBL1955292 | 0.69 | — | — | |
| SCHEMBL27584891 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL28768593 | 0.68 | — | — | |
| SCHEMBL552046 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470095-A1 | INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF | Universidade do Minho (PT) | 2019-04-17 | — | — | EP | claimed |
| US-20060008506-A1 | Method for preparing therapeutic ophthalmic articles using compressed fluids | UNIVERSIDADE DE COIMBRA (PT) | 2006-01-12 | — | — | US | claimed |
| EP-1611877-A1 | Method for preparing sustained-release therapeutic ophthalmic articles using compressed fluids for impregnation of drugs | Universidade de Coimbra (PT) | 2006-01-04 | — | — | EP | claimed |
| US-11642439-B2 | Injectable and expandable composition, devices, kits, methods and uses thereof | UNIVERSIDADE DO MINHO (PT) | 2023-05-09 | — | — | US | disclosed |
| US-20210187159-A1 | INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF | ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEERING AND CELL BASED TECHNOLOGIES & THERAPIES (A4TEC) - ASSOCIAÇÃO (PT) | 2021-06-24 | — | — | US | disclosed |
| EP-3743122-A1 | INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF | Universidade do Minho (PT) | 2020-12-02 | — | — | EP | disclosed |
| WO-2019073463-A1 | INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF | UNIVERSIDADE DO MINHO (PT) | 2019-04-18 | — | — | WO | disclosed |
| EP-3470095-A1 | INJECTABLE AND EXPANDABLE COMPOSITION, DEVICES, KITS, METHODS AND USES THEREOF | Universidade do Minho (PT) | 2019-04-17 | — | — | EP | disclosed |
| US-20060008506-A1 | Method for preparing therapeutic ophthalmic articles using compressed fluids | UNIVERSIDADE DE COIMBRA (PT) | 2006-01-12 | — | — | US | disclosed |
| EP-1611877-A1 | Method for preparing sustained-release therapeutic ophthalmic articles using compressed fluids for impregnation of drugs | Universidade de Coimbra (PT) | 2006-01-04 | — | — | EP | disclosed |