SCHEMBL44051

SCHEMBL44051

NC(Cc1ccc(F)c(F)c1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.62
PTGS1 P23219 2/20 0.62
KDM4E B2RXH2 1/20 0.62
USP2 O75604 1/20 0.62
EGFR P00533 1/20 0.62
LCK P06239 1/20 0.62
FYN P06241 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
ALOX15 P16050 1/20 0.62
HTR2A P28223 1/20 0.62
PTGS2 P35354 1/20 0.62
RECQL P46063 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
PKM P14618 2/20 0.56
ALPI P09923 1/20 0.56
XIAP P98170 1/20 0.56
GRB2 P62993 1/20 0.53
PTPN1 P18031 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29481457 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL18511382 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL44052 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL1613644 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL29478416 1.00 SLC7A5 (0.62) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL23013168 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL29481456 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL28025299 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
Hydrochloric Acid SCHEMBL23013165 0.98 SLC7A5 (0.60) SLC7A5PTGS1KDM4EUSP2EGFR
SCHEMBL22557028 0.92 SLC7A5 (0.54) SLC7A5PTGS1KDM4EUSP2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304620-A1 ANTIMICROBIAL PEPTIDE AND APPLICATION THEREOF CHINA PHARMACEUTICAL UNIVERSITY (CN) 2025-10-02 US claimed
US-20250130224-A1 PHOTOREACTIVE ANTIBODY BINDING DOMAINS WITH EPITOPE TAGS FOR MULTIPLEXED ANTIBODY LABELING, DETECTION, AND PURIFICATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-04-24 US claimed
EP-4522221-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS Entrada Therapeutics, Inc. (US) 2025-03-19 EP claimed
US-20250073302-A1 CYCLIC PEPTIDES AS PROTEASOME STIMULATORS PURDUE RESEARCH FOUNDATION 2025-03-06 US claimed
US-20240368224-A1 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS OHIO STATE INNOVATION FOUNDATION 2024-11-07 US claimed
EP-4380620-A2 PHOTOREACTIVE ANTIBODY BINDING DOMAINS WITH EPITOPE TAGS FOR MULTIPLEXED ANTIBODY LABELING, DETECTION, AND PURIFICATION The Trustees of The University of Pennsylvania (US) 2024-06-12 EP claimed
EP-4358989-A2 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS Ohio State Innovation Foundation (US) 2024-05-01 EP claimed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN claimed
CN-117466974-B Antimicrobial peptide and application thereof 中国药科大学 2024-03-26 CN claimed
EP-4337676-A1 ANTIGEN-BINDING AND ANTIGEN DEGRADATION CONSTRUCTS Entrada Therapeutics, Inc. (US) 2024-03-20 EP claimed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO claimed
US-6858577-B1 Indole peptidomimetics as thrombin receptor antagonists ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2005-02-22 US claimed
US-20040063642-A1 Novel benzimidazolone peptidomimetics as thrombin receptor antagonists MILLENNIUM PHARMACEUTICALS, INC 2004-04-01 US claimed
US-20030224999-A1 Novel indole peptidomimetics as thrombin receptor antagonists ZHANG HAN-CHENG (US) 2003-12-04 US claimed
US-20030199455-A1 Novel indazole peptidomimetics as thrombin receptor antagonists MILLENNIUM PHARMACEUTICALS, INC. 2003-10-23 US claimed
US-6630451-B1 Benzimidazolone peptidometics as thrombin receptor antagonist ORTHOMCNEIL PHARMACEUTICAL, INC. 2003-10-07 US claimed
WO-2001000656-A2 NOVEL INDAZOLE PEPTIDOMIMETICS AS THROMBIN RECEPTOR ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-01-04 WO claimed
WO-2001000659-A1 BENZIMIDAZOLONE PEPTIDOMIMETICS AS THROMBIN RECEPTOR ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-01-04 WO claimed
WO-2001000657-A2 NOVEL INDOLE PEPTIDOMIMETICS AS THROMBIN RECEPTOR ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-01-04 WO claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250073302-A1 CYCLIC PEPTIDES AS PROTEASOME STIMULATORS PSMB11, PSME1, PSMC1 SLC7A5 4745/4885PTGS1 2657/4885KDM4E 3639/4885
US-20240368224-A1 BICYCLIC PEPTIDYL PAN-RAS INHIBITORS KRAS, HRAS, NRAS SLC7A5 2938/4885PTGS1 3299/4885KDM4E 4608/4885
US-20030224999-A1 Novel indole peptidomimetics as thrombin receptor antagonists PTAFR, F2R, F2RL1 SLC7A5 3680/4885PTGS1 365/4885KDM4E 4377/4885
US-20030199455-A1 Novel indazole peptidomimetics as thrombin receptor antagonists PTAFR, F2R, F2RL1 SLC7A5 4168/4885PTGS1 558/4885KDM4E 4657/4885
US-20040063642-A1 Novel benzimidazolone peptidomimetics as thrombin receptor antagonists PTAFR, BDKRB2, BDKRB1 SLC7A5 4336/4885PTGS1 688/4885KDM4E 4091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.